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effectivehealthcare-admin.ahrq.gov/sites/default/files/grading.ppt
January 01, 2013 - Additional Domains
Four “discretionary” domains:
Dose-response association
Plausible confounders … If dose-response association is present, the reviewer may upgrade the strength of evidence. … Additional Domains: Dose-Response Scores
Three scores are possible for dose-response:
Present: dose-response … Not present: no dose-response pattern observed (dose-response relationship not present)
Not applicable … for dose response.
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effectivehealthcare-admin.ahrq.gov/products/effect-dietary-digestible/research
March 01, 2025 - risk of stroke was not significantly associated with carbohydrate intake and had a less defined dose-response … Random-effects dose-response meta-analyses were conducted when feasible. Results. … Dose-response meta-analyses suggest a nonlinear relationship between the intake of digestible carbohydrates
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effectivehealthcare-admin.ahrq.gov/products/immunity-after-covid/protocol
June 01, 2021 - Condition or Domain Being Studied
Uncertainty exists regarding the immune response in individuals infected … Antibody development in response to infection (adaptive immunity) is only a part of the overall immune … response (also comprised of innate immunity), and there is limited understanding of the contribution … Do antibodies to SARS-CoV-2 confer active natural immunity (i.e. immunity due to acquired antibody response … Do antibodies to SARS-CoV-2 confer active natural immunity (i.e. immunity due to acquired antibody response
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effectivehealthcare-admin.ahrq.gov/health-topics/antidepressants
October 01, 2018 - Systematic Review Archived April 26, 2012
Treatment for Depression After Unsatisfactory Response … Research Protocol Archived June 15, 2010
Depression Treatment after Unsatisfactory Response
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effectivehealthcare-admin.ahrq.gov/products/hepatitis-c-treatment-adherence/research
December 01, 2019 - In the eight studies reporting sustained viral response (SVR), two showed a statistically significantly … Conclusions
Adherence interventions might improve patient adherence and viral response in patients
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
March 10, 2010 - Source: www.effectivehealthcare.ahrq.gov
Published Online: March 10, 2010
2
Section Comment Response … Source: www.effectivehealthcare.ahrq.gov
Published Online: March 10, 2010
3
Section Comment Response … Source: www.effectivehealthcare.ahrq.gov
Published Online: March 10, 2010
4
Section Comment Response … Source: www.effectivehealthcare.ahrq.gov
Published Online: March 10, 2010
5
Section Comment Response … Source: www.effectivehealthcare.ahrq.gov
Published Online: March 10, 2010
6
Section Comment Response
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/mental-illness-disparities_research-protocol.pdf
July 01, 2015 - to access to accurate diagnosis, health care services, and treatment; quality of
health care; and response … health care coverage;
(c) improving quality of health care; and (d) improving adherence to treatment, response … health care, including health care coverage;
(c) improving quality of health care; and (d) improving response … health care coverage; (c) improving quality of health care; and (d) improving
adherence to treatment, response … In instances where evidence from empirical studies informs the response, we will first
provide a summary
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/deprescribing-protocol.pdf
July 01, 2023 - Deprescribing to Reduce Medication Harms in Older Adults
1
Evidence-based Practice Center Rapid Response … Purpose of the Review
The overall purpose of this rapid response is to summarize the most relevant and … Methodologic Approach
For this rapid response, strategic adjustments will be made to streamline traditional … Final Report on Prioritization of Patient Safety Practices for a New
Rapid Review or Rapid Response. … procedure-manual-appendix-vi-criteria-assessing-internal-validity-individual-studies
Evidence-based Practice Center Rapid Response
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
January 07, 2016 - # Commentator
and Affiliation
Section Comment Response … # Commentator
and Affiliation
Section Comment Response … # Commentator
and Affiliation
Section Comment Response … # Commentator
and Affiliation
Section Comment Response … # Commentator
and Affiliation
Section Comment Response
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0262_05-11-2007.pdf
January 01, 2007 - Does this make a clinical difference in response to treatment?
8. … Are there clinical predictors of response to the (above) interventions?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_research-2011.pdf
January 01, 2011 - Contact individual stakeholders and document results of
individual responses for calculation of overall response … stakeholder group
Document recruitment dates
Report invitation and
participation rates (similar to
response
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effectivehealthcare-admin.ahrq.gov/sites/default/files/interactive_media_epstein_respondent.pdf
January 01, 2009 - Program
Web
site
(http://www.effectivehealthcare.ahrq.gov/index.cfm)
Slide
1:
Response … enacted
Slide
12:
How
can
IM
promote
disclosure,
clarification
and
response
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
April 01, 2013 - Additional domains were used when appropriate: dose-
response association, impact of plausible residual … changes in median
values in response to therapy. … Eight studies assessed mean
or median change from baseline in response to therapy. … – Consider further development of data on the use of
echocardiography to measure exercise response … Long-term response to calcium
channel blockers in idiopathic pulmonary arterial hypertension.
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effectivehealthcare-admin.ahrq.gov/products/major-depressive-disorder/research-protocol
December 01, 2019 - Several recent studies have highlighted differences in response to pharmacotherapy based on baseline … to two types of antidepressants (imipramine or paroxetine) begins to outpace placebo response only when … In response to that advice, we modified KQs 1b, 2b, and 3b to include moderate MDD, and we removed the … SGA + other pharmacotherapies
Outcomes
Efficacy: response, remission, speed of response … Severity of depression and response to antidepressants and placebo: an analysis of the Food and Drug
-
effectivehealthcare-admin.ahrq.gov/products/registries-guide-4th-edition/users-guide
September 01, 2020 - Since the publication of the first edition, registries have evolved significantly in response to technical … outcomes, such as patient-reported outcomes or other outcome measures, to the registry data collection in response
-
effectivehealthcare-admin.ahrq.gov/products/arthritis-psoriatric/research
December 01, 2019 - No difference in treatment response was found between the combination of an anti-tumor necrosis factor … Services in Persons With Autoimmune Disease Treated With Biologics and Other Immunosuppressants: A Rapid Response
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effectivehealthcare-admin.ahrq.gov/products/insomnia/research
December 01, 2019 - Outcome reporting and intervention effect sizes varied, and a large placebo response was often observed … Effect sizes vary, and a large placebo response is sometimes observed.
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effectivehealthcare-admin.ahrq.gov/products/plasma-cell-dyscrasias-sflc-assay-future/research
December 01, 2019 - cells in the bone marrow and produce immunoglobulins that constitute the body's normal humoral immune response … The assay could allow for quantitative monitoring of response and remission after treatment and provide
-
effectivehealthcare-admin.ahrq.gov/products/antidepressants-update/research
December 01, 2019 - data were sufficient, we conducted meta-analyses of head-to-head trials of the relative benefit of response … Statistically significant differences in response rates between some drugs are small and likely not clinically
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
January 01, 2007 - The evidence is insufficient to determine factors that
can reliably predict response or nonresponse in … The relative risk (RR) of response was
statistically significantly greater for escitalopram
than for … Speed of response. … Response to a second agent. … Maintenance of Response or Remission (KQ
2a)
Efficacy and effectiveness.