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401. Disposition of comments for CER 169 Low Back Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_disposition-comments.pdf
     February 29, 2016 - The majority of studies reported pain (rather than function). … We relied on pooled results are reported in published systematic reviews. … In some cases they were reported as WMD’s and in others as SMD’s. … We reported outcomes as reported in the systematic reviews and primary trials not included in systematic … Harms are reported separately and we reported whether outcomes were short- or long-term.

402. Crosscutting-Horizon-Scan-High-Impact-1406 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Among the 496 patients receiving Sedasys-delivered propofol, no serious adverse events were reported … No definitive marker-related adverse effects were reported.”23 Another report from a clinical trial … Study authors reported, “The median duration from hospitalization to first visit was 7 days in the … Study authors reported, “During the pilot period, we had a 70% show rate, with 78 patients seen in … Holy Cross Hospital (Silver Spring, MD) reported in January 2012 that about 11% of patients of the

403. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
     September 01, 2011 - Peer Reviewer #9 Results It appears that the literature reported is comprehensive and the authors … The following 2010 publication reported the results of a multicenter clinical trial that utilized a … The durability of effect reported following an acute response to TMS, including the relapse rates in … In that study, the authors reported a significant difference in relapse rates favoring active drug ( … This analysis is reported in Lisanby, et al (2009).

404. Disposition of Comments: Comparative Effectiveness Review 235_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: An Update of the PTSD-Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-comments.pdf
     November 04, 2020 - These data are not presented in Table 3 with other lack of reporting data because many studies reported … Suggest providing an example of what outcomes in those studies were reported and perhaps rewording … If these diagnoses were not the primary aim of a given study, they may not have been reported in the … We have updated and expanded the findings reported in this revised report. … We also list if this information is not reported or unclear.

405. Disposition of Comments: CER 227 Noninvasive Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-227-noninvasive-nonpharm-chronic-pain-comments.pdf
     April 16, 2020 - Data were abstracted as reported in the studies. … VAS or NRS on 0-10 scale (or 0-100) was most commonly reported. … CBT) are used as reported in the included studies. … As you point out, included studies rarely reported on these. … As you point out, included studies rarely reported on these.

406. #14 SUBSTANCE ABUSE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - Recently completed unphased, phase II, and phase IV clinical studies reported that daily oral zonisamide … A 2015 followup survey reported that these results were sustained 6 months after the intervention, … high intervention tolerance and acceptability.13,18 A 2013 Swiss study reported 3-month outcomes … Additionally, after 3 months, significantly fewer SA+F group patients reported any binge drinking days … A 2011 Pew Research Center study reported that 83% of adult Americans own a mobile phone, and 73% of

407. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1406.pdf
     June 01, 2014 - Phase III trials conducted to obtain FDA approval reported that patients with SBS treated with teduglutide … The researchers also reported that the most common adverse events “included headache (35%), nausea … The most commonly reported (≥10%) adverse reactions in patients treated…across all clinical studies … Many of these adverse reactions were reported in association with the underlying disease and/or use … controlled trial with an open-label extension, at week 24, patients who received teduglutide were reported

408. Transparency of Reporting Requirements: Tympanostomy Tubes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
     September 02, 2016 - Information about the design or results of studies may be reported in publications or in registry records … will capture basic intervention, outcome, study design, sample size, and whether results have been reported … When results are reported in registry records, we will describe whether registry records and publications … We will also describe which outcome- instantiations are reported in the registry record, the publication … For outcome instantiations that are reported in both, we will record whether the quantitative results

409. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
     March 10, 2010 - Trials generally reported rates of hysterectomy and other uterine outcomes based on women who had a … This information was generally not available in the published papers, and outcomes were not reported … We reported data available from the published trials. … These details are provided in Figure 24 for studies that reported them. Results P30, line 6. … as reported in Table 3, and in the text on Key Points on p. 15.

410. Patient-Centered-Medical-Home Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_executive.pdf
     July 01, 2012 - Outcomes assessed (if reported): a. Patient experiences b. Staff experiences c. … Economic outcomes No outcomes of interest reported. 7 Table A. … Summary estimates were calculated 9 using Comprehensive Meta-Analysis software and are reported … Studies varied widely in the range of outcomes reported and the specific measures used. … summary effect estimates reported in this table.

411. Disposition of Comments for Treatments for Seasonal Allergic Rhinitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/allergy-seasonal_disposition-comments.pdf
     July 17, 2013 - However, on page 242 line 41 the Authors reported restricting search to English language. … Blinding of outcome assessors seems more important when interpreting patient-reported outcomes. … Because patients are the assessors in patient-reported outcomes, we concluded that proper blinding … on a given outcome, and if each study reported variance estimates for group-level treatment effects … Does that mean that variance was not reported at all or that it was reported in different ways (e.g

412. Cer-238-Cervical-Ripening-Appendix-E-1 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-238-cervical-ripening-appendix-e-1.xlsx
     January 01, 2009 - Nonprofit Baseline data reported for those who received intervention (n=87) Herabutya, 1988 USA Poor … Nonprofit Baseline data reported for those who received intervention (n=128) Lien, 1998 USA Fair Age … NR Baseline data reported for those who received intervention (n=174) PonMalar, 2017 India Good Age … NR Baseline data reported for those who received intervention (n=80) Smith, 1996 USA Good Age, mean … NR Baseline data reported for those included in the analysis (n=273) as 12 participants were dropped

413. The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
     September 19, 2014 - We noted discrepancies between calculated and reported results when present. … We noted discrepancies between calculated and reported results when present. … In patients with chronic pain prescribed long-term opioid therapy, observational studies reported an … Three studies reported sensitivities for the Opioid Risk Tool that ranged from 0.20 to 0.99 (three … Although a number of large observational studies reported harms based on analyses of administrative

414. Comparative Effectiveness of Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
     February 01, 2012 - This specificity reported in our tables were calculated for CRC and CRC plus advanced adenomas, the … specificity reported in the Imperiale study was for any lesion. … specificity reported in the Imperiale study was for any lesion. … While they were not reported per se, they are easily calculated. … Sensitivity is reported combined for cancer plus HGD.

415. Renal-Cancer Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
     February 01, 2016 - Studies were inconsistent in which harms, if any, were reported. … Only one study was an RCT (reported in 3 articles). … cohorts, and 9 studies (reported in 10 articles) of the SEER dataset. … Three studies reported multiple comparisons. … Six studies reported multiple comparisons (i.e., three-armed study).

416. First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update--Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update_executive.pdf
     January 01, 2018 - Harms (KQ2) were reported in 126 studies (93%). … One hundred and one (75%) studies reported on followup durations of < 6 months, 10 reported on both … short- and long-term followup, and 24 reported only on longer-term followup. … Schizophrenia and Related Psychoses Twenty-eight studies reported on intermediate outcomes and 14 reported … Twenty-six studies reported on subgroup analyses.

417. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-executive-170505.pdf
     May 01, 2017 - of bias and that reported unique data were included. … If studies reported whether their outcomes met a MCID or reported on the percent of participants who … for heat and infrared, and no medium-term effects were reported for any of the interventions. … Most reported only whether any SAEs were identified. … SAEs were extremely rarely reported and not limited to active treatment groups.

418. Stakeholder-Engagement-Benefits White-Paper (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement-benefits_white-paper.pdf
     March 01, 2014 - Involve, 201221 United Kingdom Not reported Not reported Considers involvement at 3 levels: Involvement … Boote et al., 201218 United Kingdom Not reported Not reported Refining scope of the review by helping … B-16 Brett et al., 201220 United Kingdom Not reported Not reported Initial stages of research: … Involve, 201221 United Kingdom Not reported Not reported Not reported At the individual level: public … Not reported Involve, 201221 United Kingdom Not reported Not reported Keown et al., 200822 Canada

419. Research Protocol: Radiation Therapy for Brain Metastases (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
     October 10, 2019 - more or those that report a statistical power analysis for adverse events • Studies exclusively reported … (e.g., an obvious effectiveness indicator is missing) or inadequately reported (e.g., anecdotal adverse … More granular analyses will be based on the available comparisons reported in individual studies. … While we need to work with what is reported in identified studies, and studies may vary in their reporting … While the evidence table will report all patient outcomes and reported adverse events for the identified

420. CER 218 Disposition of Comments: Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
     April 23, 2019 - drug continuation with discontinuation were framed using discontinuation as the reference group and reported … We looked for evidence about a list of possible harms, and reported results about the association of … When harms are reported in this way, we are unable to assume they were systematically collected. … We agree with the reviewer’s recommendation for how trial harms should be reported. … protocol, we evaluated BMD change as an outcome only in long-term or drug holiday trials that also reported