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341. Cystic-Fibrosis-Hgh Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
     August 01, 2012 - November 2011 1 new study reported hospitalization for pulmonary exacerbations among 10 rhGH and … November 2011 In 1 new RCT, 5 rhGH recipients reported hyperglycemia (of whom 1 dropped out)24 … Leukemia: 27 cases reported (9 recurrent,15 new, and 3 that developed after rhGH discontinuation; … One case study reported an incidence of intracranial endodermal sinus tumor in a 15-year old girl … Thus although few changes seen, two patient-reported Article ID / Cohort/First Author/Year

342. Heart-Failure-Natriuretic-Peptide Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
     November 01, 2013 - Renal function: Two papers48,80 reported an inverse association between renal function and NT-proBNP … All studies except one174 reported on some parameter related to admissions. … Most studies reported on cardiovascular admissions, and three studies168,170,173 reported fewer admissions … Deaths Of the seven studies that reported on deaths, six reported all-cause mortality,167-169,171,173,175 … four reported death due to a cardiovascular cause,170,171,173,175 and only two studies reported on

343. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
     January 01, 2014 - in patient-reported outcomes in pegloticase-treated patients who had received pegloticase every 2 … Investigators reported that a large proportion of these treated patients had complete elimination of … Investigators reported that “continued normalization of plasma uric acid (PUA) was seen in 100% and … No incidence of gout flares was reported in the 2-week arm after 5-months. … Infusion reactions were reported by 21% of patients, a similar level to that reported during the original

344. CER 229 Evidence Summary: Opioid Treatments for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
     April 01, 2020 - For trials that reported likelihood of a pain or function response, the main analysis was based (in … In the primary analysis we used the data as reported in the trials; as a sensitivity analysis, all … A smaller study by the same authors reported similar findings for treatment-resistant depression (SOE … Two trials reported no differences in pain or other outcomes. … One study reported a sensitivity for predicting opioid discontinuation due to aberrant drug-related

345. Disposition of Comments_Comparative Effectiveness Review No. 256: Effectiveness of Telehealth for Women's Preventive Services (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-disposition-comments.pdf
     June 16, 2022 - Both qualitative and patient reported outcomes are included. … The risks of bias are reported overall with descriptions saying the types of risks of bias seen across … For example, the cross-sectional study reported at the end of page 14, how much of the differential … Detailed synthesis was reported for each KQ based on available data. … I suspect that no studies reported on transgender, gender non- binary, or other gender identities.

346. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
     October 01, 2021 - • No studies reported long-term cardiovascular or metabolic disease health outcomes. … • Adverse effects of the interventions were inadequately reported in many studies. … No studies reported long-term cardiovascular or metabolic disease health outcomes.

347. App-D-Opioid-Chronic-Pain-Surveillance-Report-3 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
     September 30, 2015 - level (0 to 10, 10 high): 5.7 Level of functioning (VAS, 0 to 100) 58 Urine + for opiates: 63% Self-reported … 89% Screened: 65 Eligible: 25 Randomized: 19 Analyzed: 19 LTFU: 9 Outcomes at 6 month followup not reported … 78% vs. 90% vs. 93% Black: 15% vs. 6% vs. 5% Other: 52% vs. 3% vs. 2% Hispanic: 3% vs. 4% vs. 6% Not reported … in 2 consecutive rounds before the last round of followup B) Intermittent opioid use: opioid use reported … in any one of the rounds C) No use: no opioid use reported in any rounds Enrolled: 4,172 Analyzed: 4,172

348. Public-Reporting-Cost-Measures Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-cost-measures_research-protocol.pdf
     January 13, 2014 - What measures of costs about healthcare providers and facilities have been publicly reported? … For what facilities are costs reported? c. … How are the cost data reported (e.g., dollar amounts, symbols, graphs etc.)? e. … Are the measures of costs that are being reported consumer centered? a. … Are the measures of costs that are being reported consumer-centered?

349. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-gain-prevention_research-protocol.pdf
     January 01, 2020 - weight as a health-related outcome of interest, although it is unclear if weight change was reported … • Approaches that educate the participants about an intervention will be reported in the section … Setting: • Any setting • Studies conducted in educational settings or workplaces will be reported … If a study includes a portion of participants under age 18 and results are not reported separately … Weight change must be reported in relation to an approach of interest to be included.

350. PEPTIC ULCER #11 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1512.pdf
     December 01, 2015 - Costs for the Cytosponge device have not been widely reported yet. … Patients in the rifaximin group also reported improvements of 8.1% to 9.2% in individual symptoms ( … Patients reported a median experience score of 8 (range, 6–10) for the Cytosponge on a 0–10 scale, … Endoscopy Group, Inc., Mentor, OH).13,14 Diffusion: Covidien has not widely reported costs for the … Adverse-event rates were similar and were reported in 43% of rifaximin patients and 46% of placebo

351. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - Reported charges for the procedure ranged from $7,000 to $10,000. … The cost of PRP therapy has been reported to range from $500 to $1,500 per injection, and a patient … Investigators reported that one open-label extension trial demonstrated durable responses as ES … The investigators reported that patients treated with MSC therapy had improvements in patient pain … The investigators reported that both treatment groups showed statistically significant improvements

352. Depression SSRI Surveillance Assessment_CER 62_Low-1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
     January 01, 2013 - This trial had low risk of bias, and harms were well monitored and reported. … In general, the majority of harms reported were consistent with those associated with antidepressant … A limited number of studies undertook statistical evaluation comparing The new trials reported no … No serious AEs reported. … This trial had low risk of bias, and harms were well monitored and reported.

353. Head-Neck-Cancer-Update Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer-update_executive.pdf
     December 01, 2014 - Gupta et al. reported aggregated survival results in patients with tumors in different sites. … Overall, these studies were poorly designed, executed, and reported. … , including the RCT by Rathod et al.,15 reported QOL evidence according to RT modality. … The study reported that global QOL was not significantly affected by RT technique. … Data were most often reported on overall survival and locoregional control.

354. Making Healthcare Safer IV Rapid Response_Active Surveillance Culturing of Clostridioides difficile and Multidrug-Resistant Organisms: Methicillin-Resistant Staphylococcus aureus, Carbapenem-Resistant Enterobacterales, and Candida auris (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
     May 01, 2024 - For Review Questions 6 and 7, we examined the barriers, facilitators, and required resources reported … Similar success was reported in a narrower pre-post study20 of patients undergoing cystectomy at a U.S … However, in 2023 the New York State Department of Health reported the results of a pilot study33 that … The authors also reported the cost of a single MRSA test was $102, which included the purchase price … It is unclear if the differences between the studies that reported improved outcomes and those that

355. Disposition of Comments_Comparative Effectiveness Review No. 269_Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Culture To Improve Equitable Maternal Healthcare Delivery and Outcomes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-269-respectful-maternity-care-disposition-comments.pdf
     January 02, 2024 - Patient centered and patient reported outcomes were considered in our scope (see PICOTS table). … We included text to highlight that disparities were reported for Alaska Native/American Indian … As such, we use this term as reported in the framework. … These were not reported in any study. … However, infant outcomes were not reported in any study.

356. Disposition of Comments: Comparative Effectiveness Review No. 232_Interventions for Breathlessness in Patients With Advanced Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-232-breathlessness-cancer-comments.pdf
     November 19, 2020 - The number of studies were already very limited, the sample sizes were small, not all reported these … These were not considered critical outcomes and were infrequently reported, and we did not grade or … We only identified 1 study of nebulized opioids and this is already reported separately. … We agree, this information was often incompletely reported. … Studies were included if they reported patient or caregiver reported dyspnea. – we have clarified this

357. Nursing-Staff-Shortages-Rapid-Research-Appendix-C (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research-appendix-c.xlsx
     January 01, 2024 - Barriers, facilitators, and resources reported in primary studies. Evidence Table C-7. … available NJ New Jersey NLRN Newly licensed registered nurse NQN newly qualified nurses NR Not reported … Increased job satisfaction and confidence to practise were reported in both PPs and CSPs in all selected … Second, the authors reported on the nursing team cohesion, leadership support, and early participation … Barriers, facilitators, and resources reported in primary studies Author, Year Study Design Intervention

358. Disposition of Comments_CER 241: Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-241-wheelchair-users-disposition-comments.pdf
     October 18, 2022 - However, very few studies reported that wheelchair users were included in the study, so we were unable … We report wheelchair use whenever the studies reported wheelchair use. … They reported limited evidence, especially for CVD, mortality, and other health outcomes, however there … We report wheelchair use whenever the studies reported wheelchair use.

359. Cer-250-Cannabis-Table-E5-2022-Update 0 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-table-e5-2022-update_0.xlsx
     January 01, 2022 - Life Outcomes Anxiety and Depression Outcomes Sleep Outcomes Opioid Use Outcomes Adverse Events Other Reported … NR NR NR NR Median 120 NR Overall N Baseline: 1,514 4-year followup: 1,217 Groups unclear A: Self-reported … Moderate 33764103 Gruber, 2021 Prospective cohort U.S Mixed musculoskeletal Mixed Mean 53 62* *only reported … = intravenous; MCS = mental component score; NA = not applicable; NPP = neuropathic pain; NR = not reported

360. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the PTSD-Repository Evidence Base (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-dispositIon-comments-2022.pdf
     January 01, 2022 - I am not a mental health clinician, so I would defer to others as to whether a patient-reported assessment … I assume that while the tool may be patient-reported, a clinician verifies/validates the diagnosis … The decision to include studies that include participants with PTSD based on patient- reported tools … Does this reflect a move towards more patient-reported outcomes? … Please consider adding more details about race/ethnicity when they are reported in a study.