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2001. Slide 1
      effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
      January 01, 2013 - test for interactions for prespecified covariates Describe how overall and subgroup effects will be reported … describe statistical approaches that will be used, and describe how overall and subgroup effects will be reported … describe statistical approaches that will be used, and describe how overall and subgroup effects will be reported … studies and plausible biological mechanism Describe how overall (ATE) and subgroup effects will be reported … describe statistical approaches that will be used, and describe how overall and subgroup effects will be reported

2002. Recombinant-Factor-Viia Clinician (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/recombinant-factor-viia_clinician.pdf
      October 01, 2010 - Data for adult cardiac surgery includes all reported thromboembolic events as venous and arterial events … were not reported separately

2003. Angina-Heart-Attack-Treatments Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_executive.pdf
      January 01, 2014 - Continuous variable outcomes reported by study authors included means, medians, standard deviations, … no deaths in either group; largest study reported HR 0.93 (0.83 to 1.05); no difference Table B. … no deaths in either arm; 1 study reported 1 death in the upstream GPI arm; 1 study reported similar … We did not find any limits to applicability regarding the comparisons or outcomes reported. … Very few studies reported the net benefit of their interventions.

2004. Migraine-Adults-Executive-130408 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
      April 01, 2013 - Since all outcomes in the review were self-reported, masking of outcome assessment was not essential … 5 We concluded an unknown risk of bias for studies with poorly reported risk of bias criteria. … Planned intention to treat was reported in 24 percent of RCTs. … RCTs rarely reported specifics of concomitant treatments such as exact drugs and doses. … Few RCTs reported treatment effects in patient subgroups.

2005. Antidepressant Treatment of Depression During Pregnancy and the Postpartum Period (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
      July 01, 2014 - We reported findings from these studies only for important outcomes for which evidence in pregnant … As reported in Table C, evidence for virtually all outcomes was insufficient. … Few studies reported race or socioeconomic status. … In the studies that reported race, the populations were predominantly white. … When reported, a medium socioeconomic status level was most common.

2006. PEPTIC ULCER #11 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
      January 01, 2012 - POEM did not lead to any reported serious complications. … In a fourth, nonrandomized historical control study, POEM investigators reported that the procedure … The U.S. centers have performed more than 80 the estimated 700 POEM cases reported worldwide since … Phase III trials reported that patients with SBS treated with teduglutide can significantly reduce … reported mild chest pain.

2007. final Fibromyalgia CER protocol_3-31-14 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
      April 03, 2014 - • Obese adults: Higher rates of obesity and overweight are reported in patients with fibromyalgia … Comparison of self-reported fatigue in rheumatoid arthritis and controls. … No Uncertain Not reported 10. … Yes No Not all prespecified outcomes reported, subscales not prespecified reported, outcomes … reported incompletely Uncertain Could not be ascertained 18.

2008. bipolar-disorder-treatment-protocol-140623 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
      June 23, 2014 - Grey literature search results will be used to identify studies, outcomes, and analyses not reported … We will use reported harms from RCTs, prospective cohort, retrospective case-control, and case series … Yes No Not all prespecified outcomes reported, subscales not prespecified reported, outcomes reported … Draft Diagnostic Assessment Rubric Criteria Poor Fair Good Excellent Assessment Tool Not Reported … / No Not Reported/ No Mention DSM Details of definition not provided DSM confirmed (states

2009. Obesity (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1506.pdf
      June 01, 2015 - Investigators reported that initial BMI of 38.8 kg/m2 decreased by 6.1 units, with the following mean … However, morbidly obese patients were reported to have achieved greater TBWL, and women and less-obese … Fourteen patients were reported to have developed small, clinically insignificant ulcers or erosions … noted at the time of balloon retrieval.7 3 In December 2014, Ponce and colleagues reported … Reported costs of the ReShape Duo device and implantation procedure in the United Kingdom and Canada

2010. Crosscutting-Horizon-Scan-High-Impact-1512 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1512.pdf
      December 01, 2015 - Au-Yeung and colleagues (2011) reported a study in which 111 patients ingested 7,144 monitored pills … In a study (n=8) of 3-D printed cardiovascular models, Valverde et al. (2015) reported that surgeons … results of a clinical trial of 111 subjects who ingested 7,144 ingestible markers.2 They reported, … No definitive marker-related adverse effects were reported.”2 Another report from a clinical trial … of 30 patients reported similar detection accuracy of the system.7 These 3 investigators reported

2011. Diagnosis and Treatment of Clinical Alzheimer's-type Dementia (CATD) (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
      November 02, 2018 - Data reported on function was limited and these treatments did not improve behavioral symptoms. … Reasons for exclusion at this stage will be reported. … -Yes -No -Unclear/Not Reported OPTION 1B: Study is a CCT. … ASSESSMENT GUIDANCE • Check if all outcomes reported in the methods section reported in the result … Assessment Options Rating Check if all outcomes are reported without selective analysis?

2012. 13-MDM347013 30..38 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-testing-evaluation_research.pdf
      January 01, 2009 - Whether these differences were clinically significant is not reported, but the authors call for the … to testing include reassurance, peace of mind, and the desire to avoid regret.17 These are commonly reported … Patients who received more information from the doctor reported more reassurance on the five-item scale … A study of genetic testing for BRCA1 and BRCA2 found that women testing positive for a mutation reported … among women who are offered testing but decline.30 Other reported additional effects of testing include

2013. 13-MDM347013 30..38 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/whitepaper4-bossuyt02262010-2.pdf
      January 01, 2009 - Whether these differences were clinically significant is not reported, but the authors call for the … to testing include reassurance, peace of mind, and the desire to avoid regret.17 These are commonly reported … Patients who received more information from the doctor reported more reassurance on the five-item scale … A study of genetic testing for BRCA1 and BRCA2 found that women testing positive for a mutation reported … among women who are offered testing but decline.30 Other reported additional effects of testing include

2014. #14 SUBSTANCE ABUSE (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/substance-abuse-horizon-scan-high-impact-1412.pdf
      December 01, 2014 - Centers for Disease Control and Prevention reported that of 22,114 deaths related to pharmaceutical … Additionally, opioid overdose broadly affects American communities, with high prevalence rates reported … Naloxone peak plasma concentration (Cmax) was also reported as 15% greater after Evzio administration … to reverse an opioid overdose.7 In the relative bioavailability study with healthy subjects, the reported … In the study’s comparator arm, CDER noted that volunteers reported nausea, headache, injection site

2015. Arthritis and Nontraumatic Joint Disease (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
      December 01, 2014 - Other adverse events commonly reported in patients treated with lesinurad monotherapy included constipation … When lesinurad was combined with xanthine oxidase inhibitors, commonly reported adverse events were … Data reported by the manufacturer showed that more patients treated with lesinurad and febuxostat achieved … Other adverse events commonly reported in the lesinurad monotherapy group included constipation, diarrhea … lesinurad 3 could increase the risk of renal complications.9 The most common adverse events reported

2016. 08 Functional Limitations Potential High Impact 2012-12-10 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/08_functional_limitations_potential_high_impact_2012-12-10.pdf
      January 01, 2012 - Experts were encouraged by the lower rates of relapse and delayed disease progression reported in … Investigators reported that two phase III trials with 652 patients at 90 centers in Europe and the … About 20 patients have been reported to have trialed the system thus far. … The authors reported that “median percent reduction in total partial-seizure frequency was 44.3% vs … No icatibant-related serious adverse events were reported. 66 In 2011, data were reported from

2017. Gout Executive-2016 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive-2016.pdf
      January 01, 2016 - For studies of apparent interest reported in meeting abstracts (conference proceedings), we searched … o Could not obtain article: N = 15 o Gout management only: N = 13 o No reference standard reported … The strength of evidence for this conclusion is low, based on one study that reported no adverse events … associated with joint fluid aspiration for MSU analysis or DECT, and no studies that reported on adverse … The low sensitivity reported for the knee double contour sign by Lai and colleagues was attributed to

2018. Disposition of Comments for Evidence Report 221 Behavioral Programs for Diabetes Mellitus (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
      September 28, 2015 - The justification for including studies reported since 1993 is provided in the body of the report, … Standard procedures are reported and cited appropriately. … Hypoglycemic episodes was included as an outcome for T1DM (see Table 1), and was reported by a few … Participant blinding in this manner was rarely reported. … Very few studies reported on this outcome. We have revised the wording to this effect.

2019. Lung-Cancer-Nonsurgical-Therapies Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
      June 01, 2013 - • Post-treatment toxicities were reported across studies, but no relative trend was detected among … Hemoptysis was the most common toxicity reported across studies. … Outcomes • The major beneficial health outcomes in this CER are OS, CSS, and LCT, typically reported … However, QOL data were reported only by 1 small study out of the 6 comparative studies. … Data for operable and inoperable patients would be reported separately.

2020. Antipsychotics-Adults Surveillance (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_surveillance.pdf
      August 30, 2014 - The search strategy is reported in Appendix C. … A review that examined published and unpublished clinical trials5 reported unpublished findings that … The most commonly reported other outcome was response rate. … Iloperidol is reported as inferior to haloperidol; however, outcome measures are not mentioned. … The most commonly meeting criteria for KQ4 reported. reported other outcome was response rate.