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21. Executive summary_Comparative Effectiveness Review No. 276: Diagnosis and Management of Obsessive Compulsive Disorders in Children (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-276-ocd-executive-summary.pdf
    December 01, 2024 - o The side effects of SSRIs and clomipramine were inconsistently reported, precluding graded conclusions … Results We found 117 studies (reported in 161 papers or records) that met inclusion criteria. … No study collected or reported potential harms of behavioral interventions. … Few studies reported on social determinants of health, but among those that did, study participants … No study collected or reported potential harms of behavioral interventions.

22. Stereotactic Body Radiation Therapy | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/stereotactic-body-radiation/technical-brief
    December 01, 2019 - Two reviewers abstracted information on study design, patients, and reported outcomes. … We synthesized the following variables if reported: cancer type, patient inclusion criteria, type of … Several studies reported the use of modified linacs(k = 47), CyberKnife (k = 39), Novalis Shaped Beam … The reported outcomes include tumor control/response, toxicity, and overall survival. … The most frequently reported adverse events include pain, fatigue, nausea, bleeding, and diarrhea.

23. Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2025 Update of the Evidence Base for the PTSD Trials Standardized Data Repository (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-6-draft-report-update-2025.pdf
    January 01, 2025 - Many data elements were not reported or were reported in an inconsistent manner across the available … Race and ethnicity data were sometimes reported inconsistently or not reported across some studies. … 0 0% Race and ethnicity Both race and ethnicity data reported 7 47% Only race data reported 0 … 0% Only ethnicity data reported 2 13% Neither reported 6 40% Country U.S. 7 47% The Netherlands … reported and reported using different statistics in the included studies; therefore, we had to use

24. Transparency of Reporting Requirements: Effectiveness of Treatments Options for the Prevention of Complications and Treatment of Symptoms of Diabetic Peripheral Neuropathy | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/transparency-neuropathy/research-protocol
    June 01, 2021 - Mandating that information about trials be reported through registries, such as ClinicalTrials.gov, has … Were results reported in ClinicalTrials.gov for any of the studies? … If they were, what were the differences, if any, in the results reported in the peer reviewed literature … Were results reported in ClinicalTrials.gov for any of the studies? … We will compare the total adverse events reported in ClinicalTrials.gov compared with the total reported

25. Rapid Evidence Product: Adverse Events Associated With COVID-19 Pharmaceutical Treatments (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
    March 01, 2024 - Three studies reported serious bleeding events. … Four studies reported serious thrombotic events;4, 35, 48, 52 three of the these reported elevated risk … Adverse Events More Than 45 Days One RCT that reported at 14 days also reported serious adverse events … Both studies reported adverse events at two months; the tocilizumab trial also reported at four weeks … Timing: Not reported Control: No intervention 3rd arm: Sotrovimab 3rd arm dose: Not reported

26. Public Reporting of Cost Measures in Health | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/public-reporting-cost-measures/technical-brief
    December 01, 2019 - State departments of health or state hospital associations operated 75 percent of the 59 Web sites that reported … All the Web sites reported on inpatient care and 71 percent reported average charges. … Only 2 percent of these Web sites reported out-of-pocket costs, 7 percent reported costs using symbols … or figures, and 14 percent reported current-year data. … quality data, a lack of public awareness, and the need for research demonstrating the impact of publicly reported

27. Supplemental Project To Assess the Transparency of Reporting Requirements for Studies Evaluating the Effectiveness of Treatment Options for Symptoms of Diabetic Peripheral Neuropathy (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-neuropathy_research.pdf
    March 01, 2018 - We compared the total adverse events reported in ClinicalTrials.gov with the total reported in the … CT.gov reported more adverse events. … SF-36 PCS Yes CT.gov record reported the change from baseline in each arm, but the publication reported … Baseline values were not reported. … Baseline values were not reported.

28. Retention Strategies for Medications for Addiction Treatment in Adults With Opioid Use Disorder: A Rapid Evidence Review (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/mat-retention-strategies-rapid-review-1.pdf
    August 01, 2020 - The 1 RCT that reported harms used daily naltrexone and reported adverse events in 8 out of 67 participants … This same study also reported higher self-reported burden on participants and found the intervention … KQ2: Not reported KQ3: Not reported Fair B-6 Topic Author, Year, Study Design Country … C 49/78 (63%) 95% CI 52–74, p = 0.136 KQ2: Not reported KQ3: Not reported Fair B-7 … ) KQ2: Not reported KQ3: Not reported Fair Shi, 201924 RCT USA 20 Mean Age: 18+ Gender

29. Creating Efficiencies in the Extraction of Data From Randomized Trials: A Prospective Evaluation of a Machine Learning and Text Mining Tool | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/creating-efficiencies-extraction-data/methods-report
    August 01, 2021 - Key Messages The tool identified the reporting (reported or not reported) of data elements more than … or not reported) ≤50 percent of the time. … quantified performance by evaluating the tool’s ability to identify the reporting of data elements (reported … or not reported), and the relevance of the extracted sentences, fragments, and overall solutions. … The tool identified the reporting (reported or not reported) of data elements with median (IQR) 91 percent

30. Executive Summary - Nutrition as Prevention for Improved Cancer Outcomes: Comparative Effectiveness Review No. 260 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-260-improved-cancer-outcomes-executive-summary_0.pdf
    May 01, 2023 - • Low- and medium-risk-of-bias studies reported mixed results on the effect of nutrition interventions … • Among studies included in our Key Questions, few (4%, n=8) studies reported a formal evaluation of … Two low-66, 71 and three medium-risk- of-bias studies67, 69, 72 reported improvements in body weight … Four out of ten studies58, 59, 65, 70 reported improvements in adverse events and three reported improvements … reported improved quality of life,33 while another reported no benefit.23 Two studies reported mixed

31. Surveillance Report: CER 30: Comparative Effectiveness of Pain Management for Hip Fracture (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
    July 08, 2015 - The search strategy is reported in Appendix A. … All three trials reported acute pain. … Hypotension was reported in four RCTs (n = 190). … were reported Up-to-date No new research was found Multimodal Pain Management: No data were reported … Rehabilitation: No data were reported.

32. Treatments for Ankyloglossia and Ankyloglossia with Concomitant Lip-tie | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/ankyloglossia/research
    December 01, 2019 - Four RCTs reported improvements in breastfeeding efficacy using either maternally reported or observer … Mothers consistently reported improved breastfeeding effectiveness after frenotomy, but outcome measures … Three studies with significant limitations reported improvements in other feeding outcomes with frenotomy … , and four poor-quality studies reported some improvements in speech articulation but mixed results related … Comparative studies reported improvements in some measures of speech, but assessment of outcomes was

33. Healthcare Delivery of Clinical Preventive Services for People With Disabilities | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/people-with-disabilities/research
    March 01, 2025 - For breast and cervical cancer screening, studies reported most categories of barriers/facilitators and … included all types of disability; for other preventive services, fewer studies reported fewer categories … (1) Summarize reported barriers and facilitators to the receipt of clinical preventive services among … For breast and cervical cancer screening, studies reported on most categories of barriers/facilitators … and included all types of disability; for other preventive services, fewer studies reported fewer categories

34. Kidney-Stone-Prevention Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
    March 01, 2013 - Few studies reported adherence. … Composite: No results reported. … Composite: No results reported. Radiographic: No results reported. … Few studies reported adherence. … Composite: No results reported.

35. Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities Appendices (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_appendixes.pdf
    May 23, 2005 - Mean 52 Range 21 to 77 Not reported Not reported Not reported Not reported Brix et al. … Not reported Not reported 100% Not reported Not reported PET = positron emission tomography FDG … Not reported Not reported 100% Not reported Not reported Bone et al. 2003461 90 8.2 Planar, … Mean 54 (33 to 81) Not reported Not reported Not reported Not reported Krishnaiah et al. … Mean 54.4 (34 to 82) Not reported Not reported Not reported Not reported Danielsson et al.

36. Layout 1 (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
    July 01, 2009 - The studies reported heterogeneous followup durations which make classification of certain reported outcomes … Only two studies reported results after a single procedure and off AADs. … 70 studies that reported this adverse event. … studies; 19 studies reported no cerebrovascular events. … Atrioesophageal fistula was reported in 26 studies: 5 studies reported 1 case each, with event rates

37. Partial Breast Irradiation for Breast Cancer | Effective Health Care (EHC) Program
    effectivehealthcare-admin.ahrq.gov/products/partial-breast-irradiation/research
    May 01, 2023 - WBI: 80.11% (145/181) insufficient SOE No difference 2 RCTs   360 insufficient SOE Cosmesis reported … WBI: 10.34 (185/1789) insufficient SOE No difference 3 RCTs   3565 insufficient SOE Cosmesis reported … WBI: 10.99% (117/1065) moderate SOE Favors WBI 1 RCT   2135 moderate SOE Cosmesis reported by patient … , there are methodological concerns regarding the selection of studies and reported results. … (I 2 =89% and I 2 =94%, respectively) and patient-reported cosmesis (I 2 =56% and I 2= 96%).

38. Fiber-Intake-Draft-Report-Appendix-C (xls file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/fiber-intake-draft-report-appendix-c.xlsx
    January 01, 2024 - measurement timing Alexander (1) 2023 U.S 36102329 RCT cross-over < 2019 Industry funding of study Reported … 28/28 d Days 1-28 Alexander (2) 2023 U.S 36102329 RCT cross-over < 2019 Industry funding of study Reported … wk 28/28 d Days 1-28 Alyousif 2020 32025615 US NCT02778230 RCT cross-over 2017 No industry funding Reported … RCT cross-over < 2010 No industry funding Reported (No COI) Community 25-54 ys, BMI= 24 to 35 kg/m2, … RCT parallel 2012-2013 No industry funding Reported (Yes COI) Community 18-65 y, stool frequency of

39. Breast Abnormalities Update Surveillance Assessment_CER 47_Low (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_surveillance.pdf
    September 01, 2012 - ), and blinded to patient clinical information (versus not blinded or not reported). … There was a great deal of heterogeneity (I 2 = 93%) in the reported data. … <75% or not reported), and blinded to patient clinical information (versus not blinded or not reported … There was a great deal of heterogeneity (I 2 = 93%) in the reported data. … . 78,80,84-87 We combined the data reported by these studies in a bivariate binomial model.

40. Colorectal-Cancer-Staging Executive (pdf file)
    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_executive.pdf
    September 01, 2014 - Not reported Not reported Accuracy: 95% 8 Staging ERUS CT MRI PET/CT Colorectal N Not reported … Not reported Not reported For identifying affected nodes: Sensitivity: 34.3% Specificity: 100% Colorectal … No studies reported any cases of perforation. … Most of these studies reported on different factors; however, three studies reported that contrast … reported factors affecting CT’s accuracy for colorectal staging, but they reported on different factors