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161. Evidence Summary_Comparative Effectiveness Review No. 248: Prehabilitation and Rehabilitation for Major Joint Replacement (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/joint-replacement-evidence%20-summary.pdf
     November 01, 2021 - With only two exceptions, studies reported a unique (p)rehabilitation intervention and a wide range … There is insufficient evidence for various patient-reported, performance-based, and healthcare- utilization … With the exception of two interventions evaluated in two studies each, all studies reported unique ( … Very limited subgroup data was reported, precluding most evaluation of heterogeneity of treatment effects … prioritized outcomes, including strength, ROM, satisfaction with care, and QoL, were infrequently reported

162. Hypofractionated Radiation Therapy for Localized Prostate Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-key-question.pdf
     December 19, 2023 - trial to compare ultra-hypofractionation with conventional fractionation (HYPO-RT-PC) have also been reported … Additionally, new data on dose fractionation regimens, target volumes, treatment delivery, patient reported … survival, acute and late gastrointestinal toxicity, acute and late genitourinary toxicity, patient reported … Patient-Reported Outcomes in the Acute Phase of the Randomized Hypofractionated Irradiation for Prostate … Impact of Hypofractionated Radiotherapy on Patient-reported Outcomes in Prostate Cancer: Results up

163. Disposition of Comments: Comparative Effectiveness Review No. 238 Cervical Ripening in the Outpatient Setting (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-238-cervical-ripening-outpatient-setting-comments.pdf
     March 22, 2021 - These were not reported well, and were noted in study limitations and as areas for future research. … details to the results text where possible, and noted the variability in how these were defined or reported … o Parity: Noted that there were differences in how studies reported parity, some not reporting on it … o Baseline Bishop score in studies of interventions that require an open cervix were rarely reported … , or reported only as a median/mean for the whole group, not by intervention group.

164. Partial Breast Irradiation for Breast Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
     January 31, 2023 - Table 3 demonstrates the categories of adverse events reported. … treatment, as reported by the studies and defined in the methods on page 10. … is reported in table I2 of the appendix, which we now referenced in the results. … We clarified that the 69% is “any telangiectasia” as reported in the study. … We conducted these subgroup analyses based on available data reported by the studies, reported

165. Postpartum Home Blood Pressure Monitoring, Postpartum Treatment of Hypertensive Disorders of Pregnancy, and Peripartum Magnesium Sulfate Regimens for Preeclampsia With Severe Features | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/hypertensive-disorders-pregnancy/protocol
     April 01, 2022 - care* Ease of access to care Quality of communication Support to manage HTN Patient Reported … outcomes Patient reported experience measures (PREMs) , for example Satisfaction with care* … Quality of communication Support to manage preeclampsia treatment Patient reported outcome … We expect to primarily rely on reported within-study differences in effects (or harms). … Patient-reported outcome measures and patient-reported experience measures.

166. Hepatitis-C-Treatment-Adherence Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
     September 22, 2011 - We reported odds ratios (ORs) for dichotomous outcomes. … Studies reported highly variable outcomes. … Only two studies27,28 reported QOL outcomes. … Adherence Two studies35,36 reported adherence outcomes. … In addition, no studies reported on HCV transmission.

167. Psoriasis-Chronic Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/psoriasis-chronic_executive.pdf
     November 01, 2012 - Studies must have reported at least one of the prespecified outcomes (intermediate, final, or harm) … There was insufficient evidence to grade BSA, and no other intermediate outcomes were reported. … No other intermediate outcomes were reported. … outcomes, and no other final health outcomes were reported. … There was insufficient evidence for other reported outcomes.

168. Antiplatelet-Treatment Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_executive.pdf
     September 01, 2013 - to reconstruct such analyses from the reported data. … Four studies reported both clinical and intermediate outcomes. … Three publications reported data from the same population. … All studies reported information on clinical outcomes. … One reported no severe bleeding events and the other reported no significant effect modification.

169. Financing and Economics of Conducting N-of-1 Trials (Chapter 3) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/n-1-trials/research-2014-2
     August 01, 2019 - use of n-of-1 trials to improve therapeutic decisionmaking and clinical outcomes has been studied and reported … A systematic review by Gabler et al. found that most trials (69%) reported receiving Institutional Review … The reported costs vary widely, partly perhaps because of differences in costs between countries (one … Not reported NSAIDs Pope 4 Canada 2002-03 Not reported Not reported $31.91/6 months … Trials reported to date have found limited differences in outcomes between n-of-1 participants and usual

170. Disposition of Comments_Comparative Effectiveness Review No. 245: Breast Reconstruction After Mastectomy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-245-breast-reconstruction-after-mastectomy-disposition-comments.pdf
     October 01, 2021 - BIA-ALCL was not reported by the studies included in the review. … BIA-ALCL was not reported by the studies included in the review. … the Evidence Summary and Table 32 in the Discussion) specify that no data regarding BIA- ALCL were reported … We also included a range of other patient-reported outcomes, such as quality of life, physical well-being … We also included a range of other patient-reported outcomes, such as quality of life, physical well-being

171. A Systematic Review of Postpartum Home Blood Pressure Monitoring, Postpartum Treatment of Hypertensive Disorders of Pregnancy, and Peripartum Magnesium Sulfate Regimens for Preeclampsia With Severe Features (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/hypertensive-disorders-pregnancy-protocol-amendment.pdf
     April 20, 2022 - outcomes o Patient reported experience measures (PREMs) for example ▪ Satisfaction with postpartum … Experience Measure of Obstetric racism (PREM-OB Scale) o Patient reported outcome measures (PROMs … experience measure, PROM = patient reported outcome measure, QoL = quality of life IV. … We expect to primarily rely on reported within-study differences in effects (or harms). … Patient-reported outcome measures and patient-reported experience measures.

172. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive.pdf
     October 01, 2006 - Thirty-seven of these studies reported on adverse events. … However, only in the studies of angioplasty with stent placement were some patients reported to have … However, improvements in kidney function were reported only among patients receiving angioplasty. … No study of medical interventions reported cardiovascular outcomes. … Other adverse events reported included hemorrhage and hematomas, and renal artery occlusion.

173. Executive Summary_Systematic Review: Interventions To Improve Care of Bereaved Persons (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bereaved-persons-research-executive-summ.pdf
     March 01, 2025 - No study evaluated the clinical impact of the screening process and none of the studies reported on … None of the studies reported on the clinical impact of a correct or incorrect diagnosis. … (SMD 0.40; CI -0.23, 1.04) Insufficient Self-help intervention Quality of life Both studies reported … All studies evaluated psychotherapy but reported on different outcomes and/or comparators. … None of the studies reported on other key outcomes such as continued meeting grief disorder criteria

174. Management of Renal Masses and Localized Renal Cell Carcinoma: Current State of the Evidence | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/renal-cancer/clinician
     December 01, 2019 - This review includes 147 studies reported in 150 publications from January 1, 1997, through May 1, 2015 … Most of the patient populations in the reported composite models had a mean age of 60 years or older, … Tumor seeding was not reported in any study included in the review. … Studies in which harms, if any, were reported were inconsistent. … Transfusion: RR 1.08 (0.63 to 1.87) [evidence low] Harms 7 (2,000) Inconsistently reported

175. Restless-Legs Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
     November 01, 2012 - In the four studies that reported race,40,44-46 study participants were predominantly white. … Most studies reported treatment withdrawals greater than 20 percent at 1 year. … iron 9 therapy.15 No subjects in the placebo arm reported these events. … Other scale scores are often reported. … Trials reported a large placebo effect, thus future studies require adequate blinding.

176. Pressure-Ulcer-Treatment Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
     May 01, 2013 - Notably, many studies reported findings in terms of wound size reduction rather than complete wound … Data Synthesis Due to the heterogeneity of outcomes reported and the limited number and quality of … Other outcomes, including pain, were reported sporadically. … Surgery Surgery, all strategies Insufficient No studies reported results by patient care settings. … and inconsistently reported in support surface studies.

177. Tinnitus Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
     August 01, 2013 - Adverse effects were not consistently reported or specified in the methods of the studies. … Adverse effects were not consistently reported or specified in the methods of the studies. … Eight studies clearly stated there were no adverse effects reported.45-49,52,60,61 One study62 reported … Our review also showed that adverse effects were generally poorly evaluated and reported. … Some studies reported an absence of adverse effects, but in one study, some patients reported that

178. Treatment of Stage I-III Squamous Cell Anal Cancer | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/anal-cancer-treatment/research
     March 01, 2025 - Evidence was insufficient for patient-reported outcomes such as bowel, urinary, and sexual function. … evidence Comparison Outcome Study Number, Design, and Participants (n) Summary of Individual Study Reported … One RCT reported that the addition of paclitaxel to CRT with capecitabine plus MMC may increase treatment … Furthermore, evidence concerning patient-reported outcomes is insufficient. … Evaluating patient-reported outcomes such as bowel function (fecal incontinence, urgency, proctitis,

179. Treatment for Bipolar Disorder in Adults: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/bipolar-disorder-treatment/final-report-2018
     December 01, 2019 - Participants on atypical antipsychotics, except for quetiapine, reported more extrapyramidal symptoms … , and those on olanzapine reported more weight gain, compared with placebo. … Participants using atypical antipsychotics, except quetiapine, reported more extrapyramidal symptoms … compared to placebo, and those using olanzapine reported more clinically significant weight gain.

180. Diagnosis and Treatment of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/chronic-fatigue/research
     December 01, 2019 - Self-reported symptom scales may differentiate ME/CFS patients from healthy controls but have not been … Fourteen studies reported the consequences of diagnosis, including perceived stigma and the burden of … GET was associated with higher numbers of reported adverse events compared with counseling therapies … Harms were generally inadequately reported across trials.