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141. Pharmacologic and Nonpharmacologic Treatments of Posttraumatic Stress Disorder (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-repository-expanded-protocol.pdf
     October 24, 2019 - Indicate if subgroup analyses are reported (Y/N) n. … Between-group effect sizes for all reported anxiety outcomes n. … Between-group effect sizes for all reported sleep outcomes o. … Between-group effect sizes for all reported anger outcomes p. … Results for all reported substance use outcomes s.

142. ADHD Diagnosis and Treatment in Children and Adolescents | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/attention-deficit-hyperactivity-disorder/research
     November 01, 2024 - Monitoring: Very few monitoring studies have been reported, and more research is needed on how youth … We included 550 studies reported in 1,097 publications (231 studies addressed diagnosis, 312 studies … Diagnostic studies reported on the diagnostic performance of numerous parental ratings, teacher rating … Few studies reported estimates for children under the age of 7. … In total, 548 studies reported in 1,092 publications met the eligibility criteria.

143. Comparative Effectiveness of Pharmacologic Therapies for the Management of Crohn’s Disease | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/crohns-disease/research-protocol
     December 01, 2019 - Our proposal will address these aims, as well as the safety and patient-reported outcomes representing … We also aim to review the effects on patient quality of life as measured by patient-reported outcomes … Objectives We aim to compare the effectiveness, safety and patient-reported measures of individual … Patient-reported outcomes by remission and medication status will be measured by standard quality of … For KQ4, the outcome of interest is patient-reported outcomes measured with the same quality of life

144. Evidence Summary_Pharmacologic and Nonpharmacologic Treatments for PTSD: An Update of the PTSD-Repository Evidence Base (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-235-pharma-nonpharma-ptsd-update-summary.pdf
     November 01, 2020 - • Reporting was incomplete for many data elements in published studies: less than half of studies reported … Limitations Many data elements were not reported or were reported in an inconsistent manner across … For example, less than half of the included studies reported loss of PTSD diagnosis or clinically meaningful … Several other data elements that were infrequently reported include the number of participants with … suicide-related inclusion/exclusion criteria as well as outcomes), and also documented when these data were not reported

145. Rapid Evidence Product Addressing Social Isolation To Improve the Health of Older Adults A Rapid Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rapid-social-isolation-older-adults-final.pdf
     February 01, 2019 - Of the 16 studies, 342-44 reported information on costs: 1 RCT reported the cost of delivering the intervention … Two of these studies reported finding adverse events: one reported similar rates in both intervention … Exact timepoint not reported: • Overall SF-36 scores not reported. … • 55% reported frequently experiencing increased energy levels • 68% reported frequently … No p-value reported.

146. Comparative Effectiveness Review No. 262_Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-262-pharmacotherapy-alcohol-summary.pdf
     November 01, 2023 - edition3 criteria for alcohol use disorder in the past year.4, 5 Only 0.9 percent of Americans who reported … In particular, although some studies reported all adverse events, others only reported them in the situation … Serious harms were rarely reported, but some minor harms such as diarrhea and dizziness were common … Baclofen studies reported an increased likelihood of dizziness, drowsiness, numbness, and sleepiness … Trials of topiramate reported increased risks of many adverse events, including paresthesias, taste

147. First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/antipsychotics-adults/research
     December 01, 2019 - total scores) For schizophrenia, clozapine was more efficacious than chlorpromazine based on the one reported … Haloperidol was favored over quetiapine based on one of four scales reported. … For bipolar disorder, haloperidol was favored over ziprasidone on the one scale reported. … The most frequently reported adverse events with significant differences were extrapyramidal symptoms

148. Menopause Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - For the adverse events question, trials included in Key Question 1 that also reported adverse events … Psychological Symptoms Just over one-third of trials examining symptom treatment reported at least … There were a number of ways to obtain effect sizes from the continuous measures reported. … Vasomotor symptoms were reported in about three-quarters of trials, but all other outcomes were reported … For some of the outcomes reported, the outcome was stated as primary in only half of the studies.

149. Engaging-Caregivers-Appendix-C (xls file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-c.xlsx
     January 08, 2024 - No Yes NR Yes Yes Moderate Torke, 2016 Yes Yes No No No No No Yes No High Abbreviations: NR = not reported … 2021 (Pre-Post) Unclear No No No Yes No No Yes Critical Abbreviations: NA = not applicable; NR = not reported

150. Executive Summary_Comparative Effectiveness Review No. 273_Treatment of Stages I-III Squamous Cell Anal Cancer: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-273-anal-cancer-executive-summary.pdf
     August 01, 2024 - de-escalation or escalation in CRT; immunotherapy; posttreatment surveillance strategies; and patient-reported … Evidence was insufficient for patient- reported outcomes such as bowel, urinary, and sexual function. … Comparison Outcome Number of Studies; Study Design; Participants (n) Summary of Individual Study Reported … favored over RT alone; estimated improvement by 32% at 5yrs (p=0.002); estimates for each arm not reported … appropriate methodology such as “target trial emulation” for drawing causal inferences, include patient-reported

151. Liver-Cancer Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
     October 01, 2014 - Almost all studies reported sensitivity, but only 130 reported specificity or provided data to calculate … Seven studies reported comparative effects on clinical decisionmaking, three studies reported comparative … One study reported harms. … Seven studies reported effects of imaging on transplant decisions, and one study reported comparative … No study on US with contrast reported harms.

152. Measuring Primary Healthcare Spending | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/primary-healthcare-spending/tech-brief
     November 01, 2024 - Importantly, when primary care spending is reported as a percentage of total healthcare spending, a similar … Forty-four estimates reported on primary care spending for a single State, one estimate reported spending … for the New England States, and 22 reported national spending. … State, regional, or national estimates are either reported as two estimates, one using a narrow and one

153. Heart-Failure-Transition-Care Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_executive.pdf
     May 01, 2014 - HF = heart failure; MDS = multidisciplinary; NR = not reported (no trials in this category reported … Most trials reported rates over 3 to 6 months. … ; when these were reported, few trials reported measures in the same manner or at similar timepoints … No trial reported the number of acute outpatient (non-ER) visits. … Only two eligible trials reported information on different subgroups.

154. Crohns-Disease Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/crohns-disease_executive.pdf
     February 01, 2014 - We looked for data on these outcomes at the last reported time point. … –54 weeks and last reported time point. … All RCTs that reported on safety-related outcomes were eligible. … Most patient-reported outcomes were measured by the IBDQ. … No study reported patient-reported outcomes after surgical resection.

155. Role of Immunotherapy in the Treatment of Asthma | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/asthma-immunotherapy/research
     May 01, 2019 - Life-threatening events (such as anaphylaxis) are reported rarely. … Life-threatening reactions were not commonly reported, with three case reports of anaphylaxis (insufficient … SOE) and no deaths (moderate SOE) reported. … Life-threatening events (such as anaphylaxis) were reported rarely.

156. Therapies for Children With Autism Spectrum Disorder: Behavioral Interventions Update | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/autism-update/research
     December 01, 2019 - The quality of studies improved compared with that reported in the earlier review; however, our assessment … Studies of play/interaction-based approaches reported that joint attention interventions may demonstrate … Studies examining the effects of cognitive behavioral therapy on anxiety reported positive results in … Smaller short-term studies of other interventions reported some improvements in areas such as sleep and

157. Diagnosis and Management of Infantile Hemangioma | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/infantile-hemangioma/research
     December 01, 2019 - studies, 42 addressed effectiveness outcomes (6 good, 22 fair, and 14 poor quality), and 144 studies reported … Two small studies reported differing findings for the sensitivity of ultrasound and effectiveness of … Most studies reported a higher success rate with longer-pulse PDL compared to observation, with differing … Multiple case series reported associations between multiple cutaneous lesions and airway or hepatic IH

158. Pain Management Interventions for Hip Fracture | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/hip-fracture-pain/research
     December 01, 2019 - Most studies examined peri- and postoperative pain management, albeit from few perspectives such as reported … Long-term pain was not reported, and other outcomes were reported infrequently. … Although most studies reported on adverse effects, they were short term and not adequately powered to

159. Resource Allocation and Pandemic Response: An Evidence Synthesis To Inform Decision Making | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/allocation-scarce-resources/rapid-review
     July 01, 2021 - Most research exists to reduce care demand (n=149); higher quality studies reported benefits of contact … We identified 28 evaluations of strategies to augment resources; higher quality studies reported the … Strategies to optimize existing resources were assessed in 23 studies; higher quality studies reported … -19) research is emerging; four higher quality studies evaluated combinations of interventions; one reported

160. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_2012-12-11.pdf
     January 01, 2012 - CDC also reported that researchers calculated that U.S. medical expenditures attributed to obesity … The authors reported, “Least-squares (LS) mean weight loss for phentermine-topiramate patients who … Researchers reported that implantation was successful in 26 of 30 patients; however, the device was … Adverse events were reported in 100% of patients in this study. … The majority were reported as abdominal pain and nausea during the first week after implantation;