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121. Disposition of Comments for CER 183 Tonsillectomy for OSDB (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
     January 17, 2017 - We extracted and reported p values where reported, but we generally did not calculate them if not reported … Few studies reported longer term data, but we have reported it where available. … We extracted and reported p values where reported, but we generally did not calculate them if not reported … We extracted and reported p values where reported, but we generally did not calculate them if not reported … of ibuprofen reported bleeding; one of 2 studies of ketorolac reported bleeding.

122. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
     January 01, 2012 - Authors reported the following: Patients treated with Qnexa had significant, sustained weight loss … The authors reported, “Least-squares (LS) mean weight loss for phentermine/topiramate patients who … The majority of these events were reported as abdominal pain and nausea during the first week after … implantation; however, 23% of patients were reported to have vomiting during the first week after … The potential was tempered by experts’ significant concerns about reported adverse events.

123. Unreported Links Between Trial Registrations and Published Articles Were Identified Using Document Similarity Measures in a Cross-Sectional Analysis of ClinicalTrials.gov | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/grant-manuscripts/unreported-links-abstract
     June 01, 2024 - ClinicalTrials.gov registrations and 276,307 PubMed articles and tested methods for ranking articles across 16,005 reported … best-performing concept-based representation produced a median rank of 3 (interquartile range [IQR] 1-21) for reported … identified unreported links, and term-based representations produced a median rank of 2 (1-20) for reported … Conclusion: Leveraging the growth in the corpus of reported links between ClinicalTrials.gov and PubMed

124. Hemorrhage-Postpartum Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
     April 01, 2015 - One retrospective cohort study reported successful 7 control of bleeding following oxytocin and … Four studies of rFVIIa reported on thrombotic events, but sample sizes were small and studies were … Few studies of uterine balloon tamponade reported adverse events, and studies of embolization reported … Methods for estimating blood loss, when reported, varied and were limited. … Need for reoperation was reported after hysterectomy.

125. Breast-Biopsy-Update Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
     September 01, 2014 - Thus we grouped studies into two categories: (1) studies that explicitly reported that more than 15 … percent of included patients were at high risk of cancer; (2) studies that reported that fewer than … We contacted authors to clarify information reported in their papers and to verify suspected overlap … Another study reported that 6.3 percent of open surgical biopsies were complicated by infections. … One study reported low levels of pain with open biopsy when local lidocaine was used.

126. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_executive.pdf
     September 01, 2011 - Because five studies originated in the Matria database, and not all reported geographic region and/or … No studies reported neonatal hypocalcemia or ileus. … Outcomes Surrogate outcomes were the most commonly reported. … Long-term outcomes have not been reported at all. … Important cointerventions, such as administration of corticosteroids, should be reported.

127. Obesity (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/obesity_hi_impact.pdf
     April 17, 2012 - CDC also reported that U.S. medical expenditures attributed to obesity totaled about $147 billion in … They reported improvements in fasting insulin and glucose levels and blood pressure for lorcaserin … The investigators reported that, “At one year, using Modified Intent-to-Treat with Last Observation … were reported to have pseudopolyp formation postexplantation, and 38.5% of patients were reported … The study reported results on 17 obese patients with T2DM who received EndoBarrier for 24 weeks.

128. Disposition of Comments Report for Evidence Report 215 Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
     January 01, 2020 - Instead, only general categories were reported. … ORs were calculated for all reported events. … Clinical trials have reported no SAEs in the short term. … (No cases of anaphylaxis were reported.)” … (No cases of anaphylaxis were reported.)”

129. Public-Reporting-Cost-Measures Technical-Brief (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/public-reporting-cost-measures_technical-brief.pdf
     March 01, 2015 - All the Web sites reported on inpatient care and 71 percent reported average charges. … Only 2 percent of these Web sites reported out-of-pocket costs, 7 percent reported costs using symbols … average charges 42 71% Year of data: Reported data from 2011 and later 44 76% Reported data from … reported. … All of the Web sites reported information on inpatient services and about half of the Web sites reported

130. Health-Careassociated-Infections Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_executive.pdf
     November 01, 2012 - Of these 88 articles, 5 articles reported on 2 types of infection, 3 articles reported on 3 infections … on CLABSI,11,32,43 three reported on VAP,15,45,47 and two reported on SSI.52,55 One45 was of higher … reported on VAP, three reported on SSI,53,60,61 and two reported on CAUTI.14,61 Three20,31,53 were … care.34,46 One reported on CLABSI34 and one reported on VAP.46 One46 was of higher quality and the … Twenty-nine studies (four20,24,27,44 of which reported on two infections each) 18 reported at

131. Menopause Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - For the adverse events question, trials included in Key Question 1 that also reported adverse events … Psychological Symptoms Just over one-third of trials examining symptom treatment reported at least … There were a number of ways to obtain effect sizes from the continuous measures reported. … Vasomotor symptoms were reported in about three-quarters of trials, but all other outcomes were reported … For some of the outcomes reported, the outcome was stated as primary in only half of the studies.

132. Evidence Report on the (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
     September 01, 2010 - Our proposal will address these aims, as well as the safety and patient-reported outcomes representing … We also aim to review the effects on patient quality of life as measured by patient-reported outcomes … The patient-reported outcomes will also help patients and caregivers to take into consideration the … Objectives We aim to compare the effectiveness, safety and patient-reported measures of individual … Patient-reported outcomes by remission and medication status will be measured by standard quality of

133. Liver-Cancer Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
     October 01, 2014 - Almost all studies reported sensitivity, but only 130 reported specificity or provided data to calculate … Seven studies reported comparative effects on clinical decisionmaking, three studies reported comparative … One study reported harms. … Seven studies reported effects of imaging on transplant decisions, and one study reported comparative … No study on US with contrast reported harms.

134. Methods Research Report: Creating Efficiencies in the Extraction of Data From Randomized Trials (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-report-creating-efficiencies-extraction-data.pdf
     August 01, 2021 - Key messages • The tool identified the reporting (reported or not reported) of data elements more than … or not reported) ≤50 percent of the time … The tool identified the reporting (reported or not reported) of data elements with median (IQR) 91 percent … or not reported) 50 percent of the time or less. … The tool was reliable for identifying the reporting (reported or not reported) of most data elements

135. White Paper_Machine Learning Tools To (Semi-)Automate Evidence Synthesis: A Rapid Review and Evidence Map (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/machine-learning-tools-white-paper.pdf
     December 01, 2024 - A full list of outcomes is reported in Table 2.2. … When studies reported summarized results across ESPs, we used those results. … Details for each study are reported in Table 5. Table 5. … The two studies that reported on zero-shot models (ChatGPT) for risk of bias assessment both reported … NR = not reported; PMID = PubMed identifier; RoB = risk of bias 20 4.

136. Blood-based Tests for Multiple Cancer Screening: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cell-free-dna/draft-report
     January 01, 2025 - Fifteen studies (N=91,514) reported 64 estimates of  test accuracy for 14 MCSTs (28 unique comparisons … Six studies (3 high risk-of-bias, 3 unclear risk of bias) reported prediagnostic performance estimated … positive test: one high risk-of-bias study (N=9,911 women) evaluating cell-free DNA with nine proteins reported … We identified no studies that reported the benefits or harms of screening with MCSTs, though some ongoing

137. Disposition of Comments_Comparative Effectiveness Review No. 275: Healthcare Delivery of Clinical Preventive Services for People With Disabilities (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-275-people-with-disabilities-disposition-comments.pdf
     September 16, 2024 - ADLs and IADLs were included in the Background as reported by the U.S. Census Bureau. … We described factors as being barriers or facilitators as reported in the included studies. … Characteristics of individual included studies are reported in Appendix Table E-1 on Key Question 1 … This will allow an interested reader to find particular studies that reported on particular barriers … Table 13 – I am confused why history of sexual assault is reported as an “environment-level” barrier

138. Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/effect-dietary-digestible/research
     March 01, 2025 - Review on Risk of Type 2 Diabetes, Growth, Size, and Body Composition A majority of the included studies reported … When digestible carbohydrate intake was reported as the percentage of total energy intake, the risk of … When digestible carbohydrate intake was reported as grams per day, the risk of incident T2D gradually … The majority of the studies reported inadequate confounding adjustment (73%) and were deemed to have … The majority of the studies reported inadequate confounding adjustment (79%) and were deemed to have

139. Strategies To Prevent Weight Gain Among Adults | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/weight-gain-prevention/research
     December 01, 2019 - independently reviewed titles, abstracts, and articles, and included English-language articles that reported … The timepoints of interest for weight outcomes were: 1 year, 2 years, 5 years, and the last reported … For the other outcomes, we abstracted data only from the last reported timepoint on or after 1 year. … When reported, adherence to interventions tended to be below 80 percent. … There were no adverse events among the few trials that reported on adverse events.

140. Therapies for Clinically Localized Prostate Cancer: Update of a 2008 Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/prostate-cancer-therapies-update/research
     December 01, 2019 - trials (RCTs) and nonrandomized comparative studies published in English that evaluated treatments and reported … three-dimensional conformal radiotherapy (3D-CRT) with 3D-CRT plus androgen-deprivation therapy (ADT) reported … Six nonrandomized comparison studies reported that all-cause and prostate cancer–specific mortality was … Adverse events such as urinary incontinence and erectile dysfunction were reported mostly among men who … adverse events such as genitourinary toxicity, gastrointestinal toxicity, and erectile dysfunction were reported