-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol.pdf
November 03, 2014 - Hyperuricemia can be the result of
either inadequate renal excretion of UA or, less commonly, UA overproduction … XOIs-
allopurinol and febuxostat) to reduce sUA production; uricosurics probenecid, which
prevents renal … differ according to patient baseline
demographic characteristics and co-morbid conditions (including renal … • Patients with comorbidities, including hypertension, Type 2
diabetes, chronic kidney disease (renal … conducted by age group; particular
comorbidities, such as patients with hypertension, type 2 DM, or renal
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
December 01, 2014 - gout purportedly have insufficient excretion of uric acid, which
could be due to genetic defects in renal … organic anion transporter involved
in controlling the reabsorption of uric acid from the proximal renal … Monotherapy lesinurad resulted in more patients
experiencing elevated serum creatinine levels and renal … However, better gout management could reduce hospitalizations and renal or
cardiovascular complications … also provide cost offsets from treatment with lesinurad.18 One research expert
noted concerns over renal
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/erythropoiesis-stimulating-agents-utilization_research.pdf
February 01, 2011 - Chronic renal disease affects more than 26 million Americans1
and is the cause of significant morbidity … a common complication, conveys signifi-
cant risk for cardiovascular disease, faster progression of renal … failure, and decreased quality of life.3 In fact, most patients
with chronic renal disease become … Early Anemia Treatment
With Epoetin Beta [CREATE] 7 and
Correction of Hemoglobin and Outcomes
in Renal … Anemia in renal
disease: diagnosis and management. Blood
Rev 2010;24(1):39-47.
4. Nurko S.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - Number 34
Effective
Health Care
2
The renin system can be triggered by sympathetic
stimulation, renal … used extensively for treatment of hypertension,
heart failure, myocardial infarction, diabetes, and renal … There appears to be a small difference in change in
diabetes control, renal function between ACEIs and … and
switch rates).
• Specific adverse events (including, but not limited to, weight gain, impaired renal … e Specific adverse events: These included, but were no limited to, weight gain, impaired renal function
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0320_06-17-2009.pdf
January 01, 2009 - associated with
these diseases (i.e., bone issues, elevated urine/serum protein, anemia, fatigue, or renal … What are the day-to-day biological variables, such as renal function, that affect the
utility of FLC
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - Harms: hypertension, congestive heart failure
(CHF), edema, and impaired renal function
• All NSAIDs … Evidence regarding the
comparative risk of renal dysfunction for celecoxib
and rofecoxib is sparse. … event (peripheral edema, hypertension, or
renal dysfunction) risk from 114 randomized trials
of COX- … , although
there was no difference for the prepecified,
primary composite renal outcome of peripheral … edema, hypertension, renal dysfunction, or
arrhythmia.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
January 07, 2016 - whether imaging was done on an
urgent or elective basis, or other details such
as the severity of renal … We know that CIN incidence varies dramatically based on baseline
renal function, and the absence of … It is hypothesized that patients with normal or near-normal renal
function "may have" a lower risk of … resulting from changes in
creatinine production, tubular secretion, volue of distribution or extra-renal … Need for renal replacement therapy is
addressed in all comparisons.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
January 01, 2010 - with DES plus a selected group of clinically important variables including: gender,
age, diabetes, renal … As expected, mortality was higher in those with diabetes, renal failure,
STEMI or CHF. … This effect was somewhat less pronounced in those with a prior history of CABG and
renal failure, with … Similarly, the
30-month risk of MI was lower in all patient subgroups except those with renal failure … (Figure 4c) However, no benefit was
observed in patients >75 years, or with diabetes, renal failure,
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-555-09-03-2013.pdf
January 01, 2013 - Completion Date: 02-13-2013
3
Control and Complications Trial (DCCT) (as measured by retinal, renal … A decrease in or prevention of diabetes-related complications (as measured by retinal,
renal, cardiovascular
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
November 01, 2013 - The BNP concentration
was inversely related to renal function. … Renal function: Two papers48,80 reported an inverse
association between renal function and NT-proBNP … Renal function: One study assessed the effect of renal
function on test performance.101 Patients were … function: One study101 examined the effect of
renal function on the ability of NT-proBNP to identify … of both BNP and NT-proBNP, and to establish cutpoints
in situations of reduced renal function
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
August 01, 2012 - I demanded from the owner of my medical
center that I immediately be referred to a renal nutritionist … Renal Data System (USRDS) and the
Behavioral Risk Factor Surveillance System (BRFSS). … Ruben Velez
Renal Physicians
Association
In asymptomatic adults with or without recognized risk … A recent study by the Chronic Renal Insufficiency Cohort
(CRIC) Study Group showed that treatment of … Diuretics, calciuria and secondary hyperparathyroidism in
the Chronic Renal Insufficiency Cohort.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
March 01, 2016 - Both colchicine and NSAIDs require dose
reduction in renal impairment. … Allopurinol treatment and its
effect on renal function in gout: a controlled study. … Description and guidelines for prevention in patients with renal
insufficiency. … Allopurinol-induced severe
hypersensitivity with acute renal failure. … Allopurinol, erythema
multiforme, and renal insufficiency. BMJ. 1996 Jan
20;312(7024):173-4.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer18-heart-disease-ace-inhibitor-arb-executive.pdf
October 01, 2009 - presence and
pattern of symptoms), dose of the ACE inhibitor or
ARB used, comorbidities (diabetes, renal … Patients with renal dysfunction have at least
as robust relative reductions in the risk of cardiovascular … Renal impairment Moderate • Combination of ACE inhibitor + ARB (ramipril +
withdrawal telmisartan) has … more discontinuations due to renal
impairment than ACE inhibitor (ramipril) alone. … Renal impairment Insufficient • No data are available evaluating ACE inhibitors or ARBs
or hyperkalemia
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stones-protocol.pdf
September 24, 2024 - Patient-centered health outcomes: Incident symptomatic stones, urinary tract
obstruction with acute renal … KQ 3, 3a, 3b, 4, 4a, 4b: Followup imaging when used
for routine surveillance (CT scan, renal ultrasound … impairment, end-stage renal disease, urinary tract
infection, stone-removal procedures/surgery, procedure … NICE Guideline - Renal and ureteric stones:
assessment and management. … stone”[tw] OR
“renal stones”[tw] OR “renal calcul*”[tw] OR “staghorn
calculi”[tw] OR “staghorn calculus
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
July 19, 2013 - empiric antibiotic-dosing regimens are based on data from
noncritically ill patients (with or without renal … with new data derived from patients
with HAP, including those who are critically ill with or without renal … Based on public comments, we have added renal dysfunction as a subgroup in KQ 3. … Subgroups:
• HAP, VAP, and HCAP
• Immunocompromised
• Age, sex, race, and ethnicity
• Renal … Roberts DM, Roberts JA, Roberts MS, et al; RENAL Replacement Therapy Study
Investigators.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
March 01, 2013 - Renal stone
epidemiology in Rochester, Minnesota: an update. … Kairaitis L, Caring for Australians with Renal I. The CARI
guidelines. … Becker G, Caring for Australians with Renal I. The CARI
guidelines. Kidney stones: cystine stones. … Becker G, Caring for Australians with Renal I. The CARI
guidelines. … Placebo versus allopurinol for renal calculi.
Journal of Urology. 1977 Jun;117(6):690-2.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
March 01, 2012 - Advances in antihypertensive therapy
have dramatically reduced cardiovascular, cerebrovascular, and renal … intake on ACEI/ARB/DRI
effectiveness or harms .
3
The impact of ACEI/ARB/DRI on progression of renal … Effect of inhibitors of the renin-angiotensin
system and other antihypertensive drugs on
renal outcomes … There appears to be a small difference in change in renal function
between ACE inhibitors and ARBs ( … Renal effects of aliskiren compared with and in
combination with irbesartan in patients with type 2
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay_research-protocol.pdf
May 02, 2011 - marrow plasma cells ≤10%
Absence of end-organ damage (bone lesions, anemia,
hypercalcemia, or renal … urinary monoclonal protein
Evidence of end-organ damage (bone lesions, anemia,
hypercalcemia, or renal … marrow
plasma cells ≥10%
Absence of end-organ damage (bone lesions, anemia,
hypercalcemia, or renal … end-organ damage, including skeletal destruction (lytic bone lesions), hypercalcemia,
anemia, and renal … This ratio remains normal in polyclonal hypergammaglobulinemia or in renal insufficiency
where free
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - • The inclusion of the safety outcomes of impaired renal function, urinary tract infections,
genital … side effects; and for
comparisons including SGLT-2 inhibitors, urinary tract infections, impaired renal … side effects; and for comparisons including SGLT-2 inhibitors, urinary tract infections, impaired
renal … one of
the following comorbid conditions:
• End-stage liver disease or cirrhosis
• End-stage renal … include studies addressing
the following safety outcomes for
KQ3:
§ Liver injury^
§ Impaired renal
-
effectivehealthcare.ahrq.gov/sites/default/files/santa_eccs2012.pdf
February 01, 2013 - Plain-‐language versions of selected topics
• Longer “stories” about more complex topics: chronic renal … Cancer (American Society of Clinical Oncology): “Even in cancer, more may
not be better.”
• Chronic
renal … failure (American Society of Nephrology): “Even in chronic
renal disease, more treatment may not be