-
effectivehealthcare.ahrq.gov/products/gout/research-protocol
November 03, 2014 - Hyperuricemia can be the result of either inadequate renal excretion of UA or, less commonly, UA overproduction … (XOIs- allopurinol and febuxostat) to reduce sUA production; uricosurics probenecid, which prevents renal … differ according to patient baseline demographic characteristics and co-morbid conditions (including renal … -5)
Patients with comorbidities, including hypertension, Type 2 diabetes, chronic kidney disease (renal … conducted by age group; particular comorbidities, such as patients with hypertension, type 2 DM, or renal
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia-2011_research-protocol.pdf
January 01, 2011 - According to the
United States Renal Data System, 67.4 percent of patients initiating dialysis had … Prevalence and management of anemia in renal
transplant recipients: a European survey. … United States Renal Data System. 2010 USRDS Annual Data Report: Vol. 2 Atlas of End-Stage
Renal Disease … The impact of anemia on cardiomyopathy, morbidity, and
mortality in end-stage renal disease. … CMS proposes new prospective payment system for
renal dialysis facilities [press release].
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - almost 60% of all organ transplants.1 Kidney transplantation is the treatment of choice for end
stage renal … Cyclosporine and tacrolimus are the most commonly used CNIs in renal
transplant recipients during the … Long
term renal allograft survival in the United States:
a critical reappraisal. … Reduced exposure to calcineurin inhibitors in
renal transplantation. … graft
dysfunction'/exp OR 'renal graft dysfunction' OR (kidney OR renal) NEAR/2
(allograft* OR alograft
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol.pdf
November 03, 2014 - Hyperuricemia can be the result of
either inadequate renal excretion of UA or, less commonly, UA overproduction … XOIs-
allopurinol and febuxostat) to reduce sUA production; uricosurics probenecid, which
prevents renal … differ according to patient baseline
demographic characteristics and co-morbid conditions (including renal … • Patients with comorbidities, including hypertension, Type 2
diabetes, chronic kidney disease (renal … conducted by age group; particular
comorbidities, such as patients with hypertension, type 2 DM, or renal
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - Osteoarthritis; Acute
shoulder pain; Fever
OA and RA:
1,500 mg 2x/day
or 3,000 mg
1x/day
Renal … in 2-3
doses; Extended-
release, 100-200
mg/day
RA: Delayed-
release, 100-200
mg/day in 3- 4
Renal … impairment(CrCl
>25 mL/min) max 150
mg/day;
Moderate renal impairment
(CrCl l<25 mL/min) max 100 … Elderly – 4.3 to 7.6
hours; Hepatic
dysfunction – 1.6 to
7.6 hours; Renal
impairment – 3.4 to
18.9 … : No SS difference b/t lumiracoxib and NSAIDs for renal
endpoint or serious liver AEs.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/survival-quality_research.pdf
April 01, 2013 - Mohamed et al.,40 evaluated the benefit-risk
preferences of patients with renal cell carcinoma, using … Progression-free survival as a clinical trial
endpoint in advanced renal cell carcinoma. … Patient benefit-risk preferences for targeted
agents in the treatment of renal cell
carcinoma. … " [Supplementary Concept] OR sunitinib OR sutent) AND ("Carcinoma, Renal
Cell"[Mesh] OR "renal cell … Sorafenib in advanced clear-cell renal-cell carcinoma.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1412.pdf
December 01, 2014 - gout purportedly have insufficient excretion of uric acid, which
could be due to genetic defects in renal … organic anion transporter involved
in controlling the reabsorption of uric acid from the proximal renal … Monotherapy lesinurad resulted in more patients
experiencing elevated serum creatinine levels and renal … However, better gout management could reduce hospitalizations and renal or
cardiovascular complications … also provide cost offsets from treatment with lesinurad.18 One research expert
noted concerns over renal
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0320_06-17-2009.pdf
January 01, 2009 - associated with
these diseases (i.e., bone issues, elevated urine/serum protein, anemia, fatigue, or renal … What are the day-to-day biological variables, such as renal function, that affect the
utility of FLC
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/erythropoiesis-stimulating-agents-utilization_research.pdf
February 01, 2011 - Chronic renal disease affects more than 26 million Americans1
and is the cause of significant morbidity … a common complication, conveys signifi-
cant risk for cardiovascular disease, faster progression of renal … failure, and decreased quality of life.3 In fact, most patients
with chronic renal disease become … Early Anemia Treatment
With Epoetin Beta [CREATE] 7 and
Correction of Hemoglobin and Outcomes
in Renal … Anemia in renal
disease: diagnosis and management. Blood
Rev 2010;24(1):39-47.
4. Nurko S.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - Number 34
Effective
Health Care
2
The renin system can be triggered by sympathetic
stimulation, renal … used extensively for treatment of hypertension,
heart failure, myocardial infarction, diabetes, and renal … There appears to be a small difference in change in
diabetes control, renal function between ACEIs and … and
switch rates).
• Specific adverse events (including, but not limited to, weight gain, impaired renal … e Specific adverse events: These included, but were no limited to, weight gain, impaired renal function
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_executive.pdf
January 01, 2006 - Harms: hypertension, congestive heart failure
(CHF), edema, and impaired renal function
• All NSAIDs … Evidence regarding the
comparative risk of renal dysfunction for celecoxib
and rofecoxib is sparse. … event (peripheral edema, hypertension, or
renal dysfunction) risk from 114 randomized trials
of COX- … , although
there was no difference for the prepecified,
primary composite renal outcome of peripheral … edema, hypertension, renal dysfunction, or
arrhythmia.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-555-09-03-2013.pdf
January 01, 2013 - Completion Date: 02-13-2013
3
Control and Complications Trial (DCCT) (as measured by retinal, renal … A decrease in or prevention of diabetes-related complications (as measured by retinal,
renal, cardiovascular
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
January 07, 2016 - whether imaging was done on an
urgent or elective basis, or other details such
as the severity of renal … We know that CIN incidence varies dramatically based on baseline
renal function, and the absence of … It is hypothesized that patients with normal or near-normal renal
function "may have" a lower risk of … resulting from changes in
creatinine production, tubular secretion, volue of distribution or extra-renal … Need for renal replacement therapy is
addressed in all comparisons.
-
effectivehealthcare.ahrq.gov/products/vte-prophyalaxis/research
May 29, 2013 - antiplatelet therapy; obese or underweight patients; those having obesity surgery; or with acute or chronic renal
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
January 01, 2010 - with DES plus a selected group of clinically important variables including: gender,
age, diabetes, renal … As expected, mortality was higher in those with diabetes, renal failure,
STEMI or CHF. … This effect was somewhat less pronounced in those with a prior history of CABG and
renal failure, with … Similarly, the
30-month risk of MI was lower in all patient subgroups except those with renal failure … (Figure 4c) However, no benefit was
observed in patients >75 years, or with diabetes, renal failure,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
November 01, 2013 - The BNP concentration
was inversely related to renal function. … Renal function: Two papers48,80 reported an inverse
association between renal function and NT-proBNP … Renal function: One study assessed the effect of renal
function on test performance.101 Patients were … function: One study101 examined the effect of
renal function on the ability of NT-proBNP to identify … of both BNP and NT-proBNP, and to establish cutpoints
in situations of reduced renal function
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_disposition-comments.pdf
August 01, 2012 - I demanded from the owner of my medical
center that I immediately be referred to a renal nutritionist … Renal Data System (USRDS) and the
Behavioral Risk Factor Surveillance System (BRFSS). … Ruben Velez
Renal Physicians
Association
In asymptomatic adults with or without recognized risk … A recent study by the Chronic Renal Insufficiency Cohort
(CRIC) Study Group showed that treatment of … Diuretics, calciuria and secondary hyperparathyroidism in
the Chronic Renal Insufficiency Cohort.
-
effectivehealthcare.ahrq.gov/products/plasma-cell-dyscrasias-sflc-assay/research-protocol
May 02, 2011 - resulting end-organ damage, including skeletal destruction (lytic bone lesions), hypercalcemia, anemia, and renal … Bone marrow plasma cells ≤10%
Absence of end-organ damage (bone lesions, anemia, hypercalcemia, or renal … urinary monoclonal protein
Evidence of end-organ damage (bone lesions, anemia, hypercalcemia, or renal … bone marrow plasma cells ≥10%
Absence of end-organ damage (bone lesions, anemia, hypercalcemia, or renal … amyloidosis
Amyloid-related systemic syndrome — organ involvement by tissue amyloid deposition (renal
-
effectivehealthcare.ahrq.gov/products/diabetes-foot-ulcer-amputation-prevalence/research
February 17, 2011 - Those with diabetes are expected to suffer from several associated medical complications, such as renal … The prevalence of LEA in nonelderly diabetics with PAD (many of whom likely have end-stage renal disease
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer18-heart-disease-ace-inhibitor-arb-executive.pdf
October 01, 2009 - presence and
pattern of symptoms), dose of the ACE inhibitor or
ARB used, comorbidities (diabetes, renal … Patients with renal dysfunction have at least
as robust relative reductions in the risk of cardiovascular … Renal impairment Moderate • Combination of ACE inhibitor + ARB (ramipril +
withdrawal telmisartan) has … more discontinuations due to renal
impairment than ACE inhibitor (ramipril) alone. … Renal impairment Insufficient • No data are available evaluating ACE inhibitors or ARBs
or hyperkalemia