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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/by8VJVre6h6BmadrGxaFMM
    April 01, 2016 - Be- cause of the time required before a reduced incidence in CRC is seen, older persons (that is, 60 … The time to benefit for CRC (that is, reduced CRC incidence and death) and time to harm are important … Nonfatal strokes were also reduced when only low- dose aspirin trials were included in the analysis ( … However, when trial re- sults were pooled, all-cause mortality risk was reduced by 5% in participants … Total cancer mortality was not significantly reduced across 10 RCTs of primary CVD prevention (4).
  2. www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-nsaids-for-prevention-of-colorectal-cancer-preventive-medication-2007
    March 15, 2007 - to prevent coronary heart disease (CHD) events in those at increased risk for CHD does not lead to a reduced … Physical activity and reduced risk of incident sporadic colorectal adenomas: observational support for … Reduced incidence of colorectal adenoma among long-term users of nonsteroidal antiinflammatory drugs: … Aspirin use and reduced risk of fatal colon cancer. N Engl J Med 1991;325:1593-6. … Nonsteroidal antiinflammatory drug use and reduced risk of large bowel carcinoma.
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
    August 24, 2017 - Women who undergo interventions may also have reduced incidence of BRCA-related cancer and reduced cause-specific … Does risk assessment, genetic counseling, and genetic testing result in reduced incidence of BRCA-related
  4. www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
    February 09, 2023 - control KQs 4, 5: Head-to-head comparisons of two active interventions Outcomes KQs 1, 4: Reduced … control KQs 4, 5: Head-to-head comparisons of two active interventions Outcomes KQs 1, 4: Reduced … exposure to abuse or neglect (e.g., reduced episodes of physical violence); physical morbidity associated
  5. www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/unhealthy-alcohol-use-adolescents-adults-behavioral-counseling-interventions
    August 05, 2025 - In pooled analysis, participants in the intervention groups reduced alcohol consumption by an average … 4.07]; number needed to treat, 6 based on control group median of 62.3%). 1 Overall interventions reduced … school students who could legally purchase alcohol found high risk but not medium risk youth reported reduced … evidence that brief behavioral counseling interventions in adults who screen positive are associated with reduced … Inadequate evidence that brief behavioral counseling interventions in adolescents was associated with reduced
  6. www.uspreventiveservicestaskforce.org/uspstf/recommendation/falls-prevention-in-older-adults-counseling-and-preventive-medication-2012
    May 15, 2012 - Although the evidence was mixed on whether interventions reduced fall-related fractures or improved quality … None of the 4 studies of vision correction reported a reduced risk for falling. … Limited evidence from 2 of the vision correction studies indicates that a fear of falling is reduced … One large study of 4169 women with an average age of 78 years reported both a reduced risk for falling … after 12 months and a reduced fear of falling 16 .
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/c-7ARQE9RuXKjjpeLABkaH
    March 01, 2007 - to prevent coronary heart disease (CHD) events in those at increased risk for CHD does not lead to a reduced … Nonsteroidal antiinflammatory drug use and reduced risk of large bowel carcinoma. … Physical activity and reduced risk of incident sporadic colorectal ade- nomas: observational support … Reduced incidence of colorectal adenoma among long-term users of nonsteroidal antiinflammatory drugs: … Aspirin use and reduced risk of fatal colon cancer. N Engl J Med. 1991;325:1593-6.
  8. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review46/hepatitis-b-virus-infection-screening-2004
    February 15, 2004 - Key Question 1: Is there new evidence of harms or reduced … No studies were identified that indicate new harms or reduced benefits from the universal screening of … vaccination program began in 1984, the prevalence of HBsAg among persons younger than 15 years of age was reduced
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/StNCYDfuKfxc2LpwtaN8et
    February 01, 2004 - Is there new evidence of harms or reduced benefits from the universal screening of pregnant women? … No studies were identified that indicate new harms or reduced benefits from the universal screening of … vaccination program began in 1984, the prevalence of HBsAg among persons younger than 15 years of age was reduced
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan95/syphilis-infection-in-nonpregnant-adults-and-adolescents-june-2016
    September 18, 2014 - Infected persons receive treatment that can lead to reduced complications of syphilis as well as reduced
  11. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-breast-cancer/breast-cancer-screening-january-2016
    January 11, 2016 - All-cause mortality was not reduced with screening. … Advanced breast cancer was reduced for women aged 50 years or older (RR, 0.62 [CI, 0.46 to 0.83]) (3 … Conclusion: Breast cancer mortality is generally reduced with mammography screening, although estimates … Advanced cancer is reduced with screening for women aged 50 years or older. … Advanced cancer is reduced with screening for women aged 50 years or older.
  12. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/intimate-partner-violence-abuse-older-vulnerable-adults
    April 20, 2023 - control KQs 4, 5: Head-to-head comparisons of two active interventions Outcomes KQs 1, 4: Reduced … control KQs 4, 5: Head-to-head comparisons of two active interventions Outcomes KQs 1, 4: Reduced … exposure to caregiver abuse or neglect (e.g., reduced episodes of physical violence); physical morbidity
  13. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening
    April 20, 2023 - control KQs 4, 5: Head-to-head comparisons of two active interventions Outcomes KQs 1, 4: Reduced … control KQs 4, 5: Head-to-head comparisons of two active interventions Outcomes KQs 1, 4: Reduced … exposure to caregiver abuse or neglect (e.g., reduced episodes of physical violence); physical morbidity
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/5W2k4HLBPLPgHov6sSvuMH
    July 24, 2018 - 2 Newborns Reduced gonococcal ophthalmia neonatorum and associated blindness Health outcomes 2 Harms … of intervention Intervention Reduced gonococcal infection 1 Evidence reviews for the US Preventive … effective in preventing GON Strong evidence that universal administration of ocular prophylaxis has reduced
  15. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/alcohol-misuse-screening-and-counseling-2004
    April 06, 2004 - interventions (those with up to 15 minutes of initial contact and at least 1 follow-up), participants reduced … Both groups comparably reduced alcohol consumption. … Mean drinks were reduced at 6 mo ( P = 0.04) but not at 12 mo ( P = 0.13). … reduced proportions bingeing at 12 mo compared with no intervention. … This brief, multicontact intervention by the PCP reduced alcohol consumption by men and women and the
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RkeQEwKRWULreuWecXG8S-
    July 01, 2013 - Among these 26 programs, triennial screening reduced total lung cancer mortality in the cohort by 5% … to 6% compared with biennial programs that reduced mortality by 7% to 10% and annual programs that … reduced mortality by 11% to 21%. … In Model E, screen- detected (and therefore earlier treated) cases experience a reduced risk of dying … Reduced lung-cancer mortality with low-dose computed tomographic screening.
  17. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/skin-cancer-counseling-2003
    October 06, 2003 - Sunscreen Use Daily sunscreen use on the hands and face reduced the total incidence of squamous cell … An earlier randomized trial demonstrated that sunscreen use reduced solar keratoses, precursors of squamous … However, most of the change was due to increased sunscreen use rather than to reduced sun exposure. … Concerns related to sun avoidance include reduced physical activity levels among children and negative
  18. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - In CVD primary and secondary prevention trials, 20-year CRC mortality was reduced among persons assigned … Cancer incidence was not reduced at any specific non-CRC site (including a priori secondary study outcomes … Even when grouped by site, only gastrointestinal cancer incidence was reduced in the posttrial follow-up … An IPD meta-analysis of 4 CVD primary and secondary prevention trials 68 suggested that aspirin reduced … Long-term cumulative risk for CRC death (0 to ≥20 years) was reduced among patients assigned to take
  19. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin/aspirin-nsaids-for-prevention-of-colorectal-cancer-preventive-medication-2007
    March 15, 2007 - Data Synthesis:  Regular use of aspirin reduced the incidence of colonic adenomas in RCTs (relative risk … Physical exercise, use of Plantago ovata and aspirin, and reduced risk of colon cancer. … Aspirin use and reduced risk of fatal colon cancer. N Engl J Med 1991;325:1593-6. … Reduced risk of large-bowel adenomas among aspirin users. The Polyp Prevention Study Group. … Nonsteroidal antiinflammatory drug use and reduced risk of large bowel carcinoma.
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/2wL_PmXmBxZQXX29D7nma5
    September 01, 2021 - It is strengthened by new evidence from additional trials demonstrating reduced risks of perinatal mortality

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