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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/MzHhsgTBL37rRvvJfkfgMZ
    August 20, 2019 - Twenty-eight studies (n = 8060) indicated that genetic counseling was associated with reduced breast … posttest counseling 3d Eligible for risk reduction Not eligible 4 Harms of interventions 5 Reduced … Similar to ta- moxifen and raloxifene, aromatase inhibitors were associated with reduced ER-positive … Risk-reducing salpingo-oophorectomy was associated with reduced ovarian can- cer incidence. … Reduced incidence of invasive breast cancer with raloxifene among women at increased coronary risk.
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RwHjq3L5fN5gdWsp_sSwA3
    August 02, 2018 - that brief behavioral counseling interventions in adults who screen positive are associ- ated with reduced … A physiological withdrawal state when substance use has ceased or been reduced, as evidenced by: the … Among 37 adult trials (n = 15 974), adults in intervention groups reduced the num- ber of drinks per … The proportion exceeding recom- mended drinking limits was reduced (odds ratio [OR], 0.60 [95% CI, 0.53 … However, ad- equate epidemiologic evidence links reduced levels of alcohol con- sumption with a reduced
  3. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/use-decision-models-development-evidence-based-clinical-preventive-services-recommendations
    May 01, 2019 - National Lung Screening Trial), 11  which showed that screening with low-dose computed tomography (CT) reduced … aspirin use for the primary prevention of cardiovascular disease and CRC 9 integrated benefits from reduced … Benefit is reduced in older adults because the risk for bleeding with aspirin increases with age and because … they are less likely to benefit from reduced CRC incidence given that this effect takes at least 10 years … Is the intermediate outcome reliably associated with reduced morbidity and/or mortality? 7.
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/4TToeya43r5Qc5A6TjFGWS
    August 01, 2023 - previously reviewed evidence from a randomized clinical trial and observational studies report- ing reduced … One cohort study reported a statistically significant reduced risk of neural tube defects associated … In contrast, in the second period (2006- 2013), the authors reported a statistically significant reduced … Dosage: 1 case-control study of women with prepregnancy obesity; n = 1429 Statistically significantly reduced … other adverse events in women 1 RCT; n = 4862 Increased risk for weight gain, diarrhea, constipation; reduced
  5. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
    August 20, 2019 - Twenty-eight studies (n = 8060) indicated that genetic counseling was associated with reduced breast … Similar to tamoxifen and raloxifene, aromatase inhibitors were associated with reduced ER-positive but … Risk-reducing salpingo-oophorectomy was associated with reduced ovarian cancer incidence. … While risk-reducing mastectomy and salpingo-oophorectomy are associated with reduced breast and ovarian … Reduced incidence of invasive breast cancer with raloxifene among women at increased coronary risk.
  6. www.uspreventiveservicestaskforce.org/uspstf/recommendation/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
    August 20, 2019 - Tamoxifen reduced invasive breast cancer more than raloxifene in the head-to-head trial (relative risk … Breast cancer–specific and all-cause mortality were not reduced. 78 In cohort studies of high-risk … reduced breast cancer mortality. … Oophorectomy was associated with 81% to 100% reduced ovarian cancer incidence. … In general, there was no association between oophorectomy or salpingo-oophorectomy and reduced breast
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/WYvNt2GWJf8uGcAm3p_PFJ
    October 05, 2021 - with universal screen- ing strategies) found benefits in outcomes such as full-term still- birth and reduced … 0.56-1.01]; ARD, 2.3%; 4 trials).29,34 Treatment of gestational dia- betes was not associated with reduced … studies (RR, 0.99 [95% CI, 0.46-2.16]; 6 trials).29 Addi- tionally, treatment was not associated with reduced … outcomes, treatment of gestational diabe- tes at 24 weeks of gestation or after was associated with reduced … Treatment of gestational diabetes was associated with a reduced risk of macro- somia (>4000 g) (RR, 0.53
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Pzrh6m8vUcdvmsaBwKaQA2
    February 01, 2014 - Breast cancer risk was reduced by 85% to 100% with mastectomy (27–29) and by 37% to 100% with oophorectomy … , and ovarian cancer risk was reduced by 69% to 100% with oophorectomy or salpingo-oophorectomy (26). … In a meta- analysis of trials published to date (26, 65), tamoxifen and raloxifene reduced the incidence … Mastectomy reduced breast cancer risk by 85% to 100%, and oopho- rectomy or salpingo-oophorectomy reducedReduced incidence of invasive breast cancer with raloxifene among women at increased coronary risk.
  9. www.uspreventiveservicestaskforce.org/uspstf/recommendation/hypertension-screening-1996
    January 01, 1996 - Deaths due to cerebrovascular disease, ischemic heart disease, and other causes were also significantly reduced … persons aged ≥ 60 years demonstrated that antihypertensive treatment in elderly persons significantly reduced … Treatment of hypertension is associated with multiple benefits, including reduced coronary heart disease … There are no trials showing that lowering blood pressure in childhood results in reduced blood pressure … blood pressure in hypertensive adults is beneficial and that death from several common diseases can be reduced
  10. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/high-blood-pressure-adults-children-adolescents-screening-2003
    April 01, 2003 - blood pressure (DBP) greater than 110 mm Hg found that treatment with reserpine or alpha-methyl dopa reduced … with DBPs of 90 mm Hg to 109 mm Hg and found that treatment of hypertension in adults younger than 60 reduced … or calcium-channel blockers) or with placebo treatment. 28 The authors found that active treatment reduced … Effect of reduced dietary sodium on blood pressure: a meta-analysis of randomized controlled trials. … Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/BXkaHRFGjwUCoyANeMSuTz
    January 01, 2010 - blood pressure (DBP) greater than 110 mm Hg found that treatment with reserpine or alpha-methyl dopa reduced … In patients older than 60, the majority of whom had blood pressures in this range, treatment reduced … The authors found that active treatment reduced stroke (RR 0.70; 95% CI 0.59 to 0.82), coronary heart … Effect of reduced dietary sodium on blood pressure: a meta-analysis of randomized controlled trials. … Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (
  12. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/drug-use-illicit-screening
    October 20, 2016 - adults, including pregnant women, may result in improved behavioral outcomes, including drug abstinence, reduced … What is the association between reduced drug use and health outcomes?
  13. www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/breast-cancer-medications-for-risk-reduction
    September 03, 2019 - Some women at lower risk for breast cancer have also been included in trials documenting reduced risk … A systematic review of trials conducted for the USPSTF found that compared with placebo, tamoxifen reduced … and Raloxifene (STAR) trial, which directly compared tamoxifen with raloxifene, found that tamoxifen reduced … 84%-97% white in studies that reported this information). 3 In trials, all 3 types of medications reducedReduced incidence of invasive breast cancer with raloxifene among women at increased coronary risk.
  14. www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction
    September 03, 2019 - Some women at lower risk for breast cancer have also been included in trials documenting reduced risk … A systematic review of trials conducted for the USPSTF found that compared with placebo, tamoxifen reduced … and Raloxifene (STAR) trial, which directly compared tamoxifen with raloxifene, found that tamoxifen reduced … 84%-97% white in studies that reported this information). 3 In trials, all 3 types of medications reducedReduced incidence of invasive breast cancer with raloxifene among women at increased coronary risk.
  15. www.uspreventiveservicestaskforce.org/uspstf/document/modeling-report/lung-cancer-screening-december-2013
    July 30, 2013 - National Lung Screening Trial (NLST) demonstrated that three annual computed tomography (CT) screenings reduced … three annual computed tomography (CT) screenings and subsequent treatment of early-stage lung cancer reduced … In Model E, screen-detected (and therefore earlier treated) cases experience a reduced risk of dying … operative mortality in older individuals with heavy smoking histories, as well as increased comorbidity and reducedReduced lung-cancer mortality with low-dose computed tomographic screening.
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Njxn2r3qtWKdBf2_VhS2Aw
    April 01, 2016 - In CVD primary and secondary prevention trials, 20- year CRC mortality was reduced among persons assigned … vention trials of daily aspirin use with median duration of at least 4 years reported that aspirin reduced … Overall cancer incidence (5071 cases, excluding nonmelanoma skin cancer) was not reduced among as- pirin … Even when grouped by site, only gastrointestinal cancer incidence was reduced in the posttrial follow-up … Long-term cumulative risk for CRC death (0 to ≥20 years) was reduced among patients assigned to take
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/4NUuvS6nmzTdBgjBg3ELkE
    January 01, 2020 - Synthesis: At 12 to 24 months, intensive lifestyle counseling in persons selected for risk factors reduced … Intensive combined lifestyle counsel- ing interventions reduced total cholesterol levels (22 trials) … Intensive diet-only counseling interventions also reduced total cho- lesterol levels (9 trials) by 0.10 … It also reduced fasting glucose levels (18 trials) by 0.10 mmol/L (CI, 0.18 to 0.03 mmol/L) (1.86 mg/ … Mortal- ity rates in treated hypertensive men with additional risk factors are high but can be reduced
  18. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan153/ovarian-cancer-screening
    March 03, 2016 - trial evidence that the stage or type of ovarian cancer diagnosed through screening contributes to reduced
  19. www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening-2002
    September 03, 2002 - Clinicians should inform women about the potential benefits (reduced chance of dying from breast
  20. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/reports-congress/tenth-annual-report-congress-high-priority-evidence-gaps-clinical-preventive-services
    January 01, 2020 - preventive care, which will hopefully lead to improved access to and use of these preventive services, reduced

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