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Total Results: 1,623 records

Showing results for "reduced".

41. CER 225: Evidence Summary Interventions for Substance Use Disorders in Adolescents: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-evidence-summary%20225%20Substance%20Use%20Adolescents.pdf
    May 01, 2020 - Our meta-analyses of brief interventions found that motivational interviewing reduced heavy alcohol … Of the multiple intensive interventions, family-focused therapies were most effective; they reduced

42. Cancer-Anemia-Update Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_executive.pdf
    April 01, 2013 - recently, randomized controlled trials have reported increased incidence of thrombotic events and reduced … Hematologic Response ESAs reduced the proportion of patients receiving transfusions (overall strength … Recent regulatory and guideline changes may have reduced ESA exposure in subsequent clinical trials

43. Treatments for Fecal Incontinence: Current State of the Evidence (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_clinician.pdf
    July 01, 2016 - injections (FDA-approved for another condition; unapproved by the FDA for fecal incontinence treatment) reduced … The negative psychological effects, social stigma, and reduced quality of life surrounding fecal incontinence … injections (both unapproved by the FDA for FI) 2 75 Severity Durasphere® tissue-bulking injections reduced

44. DEcIDE 32: The Incident User Design in Comparative Effectiveness Research (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
    May 01, 2012 - User Design .....................................................................................10 Reduced … Study Size and Reduced Precision ................................................................... … ...10 Reduced Ability to Study Long-Term Effects ................................................... … ................10 Reduced Generalizability ........................................................ … Reduced Generalizability The other main tradeoff that results from choosing to study incident users

45. Hi Les, (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/rtc-design-principles_research.pdf
    January 01, 2009 - improves patient outcomes or whether the new test produces other benefits, such as improved safety or reduced … cervical cancer incidence due to improved test sensitivity and reduced unsatisfactory slide rates. … A reduced unsatisfactory slide rate for LBC may provide immediate patient benefits by reducing patient … The potential benefits of this strategy include improved patient access and convenience with reduced … For example, full-body computed tomography (CT) might lead to reduced morbidity and mortality due to

46. Comparative Effectiveness Review No. 241_Physical Activity and the Health of Wheelchair Users: A Systematic Review in Multiple Sclerosis, Cerebral Palsy, and Spinal Cord Injury (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-241-physical-activity-wheelchair-evidence-summary-updated.pdf
    October 01, 2021 - regular physical activity (movement using more energy than rest) for the general population include reduced … This may lead to paralysis or reduced extremity muscle force and increased spasticity, which can greatly

47. Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
    May 01, 2016 - . �� Meta-analysis provided strong evidence that therapist-led CBT reduced binge-eating frequency … binge-eating abstinence and that second- generation antidepressants increased binge-eating abstinence, reduced … binge-eating frequency, and reduced eating-related obsessions and compulsions. �� Qualitative assessments … provided additional evidence that lisdexamfetamine and topiramate reduced binge-eating frequency,

48. Disposition of Comments for CER 166 Calcineurin Inhibitors (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
    March 15, 2016 - Reduced exposure to calcineurin inhibitors in renal transplantation. … Compared to cohorts receiving standard CsA, reduced CsA, and reduced sirolimus (SRL), patients receiving … Reduced exposure to calcineurin inhibitors in renal transplantation. … confined solely to studies comparing standard-to reduced-dose CsA regimens. 5. … So what caused the reduced rejection?

49. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0263_12-28-2007.pdf
    January 01, 2007 - For patients whose pancreas and/ or intestines are affected, their growth can be (possibly greatly) reduced

50. Diagnosis and Management of Gout: Current State of the Evidence (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
    January 01, 2017 - ��Urate-lowering therapy (ULT), including allopurinol and febuxostat, reduced serum urate levels (high … NSAIDs) against gout attack (high SOE). �– After 12 months of ULT, the frequency of gout attacks was reduced … �� Overdose in adults and children can be fatal NSAIDs �� Dyspepsia, abdominal pain, headache, and reduced

51. Health Information Exchange (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-information-exchange_executive.pdf
    December 01, 2015 - Studies that examined whether HIE improved resource use defined this as: (1) reduced ordering of laboratory … tests, radiology exams, and costs, especially in the emergency department (ED); (2) reduced hospital … Studies of reduced laboratory tests, radiology exams, and costs showed the most consistent associated … three more found reductions in radiology alone.9-11 A United States–based ambulatory study found a reduced … The studies of admissions and readmissions had inconsistent findings, with some reporting that HIE reduced

52. An analytical framework for quantifying components of variability in prescriber decisions (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/instrumental-variable-methods_research.pdf
    April 01, 2010 - Variable Assumptions, Informally..................................................................1 Reduced … Effective Health Care Program Research Report Number 22 3 Reduced Form or Intention-to-Treat … In the IV literature, this is termed the reduced form estimate. … In a placebo-controlled RCT with non-compliance, the reduced form estimate will be a biased estimate … An association between formulary status and reduced mortality risk would suggest that the new medication

53. Breast-Cancer-Medications Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_surveillance.pdf
    July 01, 2012 - Tamoxifen (RR 0.58; 0.42, 0.79; four trials) and raloxifene (RR 0.33; 0.18, 0.61; two trials) reduced … nonvertebral fractures; and tibolone reduced wrist (RR 0.54; 0.35, 0.82; one trial) but not hip … Tamoxifen (RR 0.58; 0.42, 0.79; four trials) and raloxifene (RR 0.33; 0.18, 0.61; two trials) reduced … Do Not Know cancer was significantly reduced in the NSABP P-1 (National Surgical Adjuvant Breast … trials, raloxifene (RR 0.61; 0.54, 0.69; two trials) and tibolone (RR 0.55; 0.41. 0.74; one trial) reduced

54. Refining Key Questions: Interactive Case Study Quiz
    effectivehealthcare.ahrq.gov/sites/default/files/rfviia.pptx
    May 01, 2010 - While the large Mayer 2005 study reported a significant dose-response effect of reduced hematoma growth … There was a trend across studies toward reduced RBC transfusion requirements with rFVIIa use vs. usual … Neither operating room time nor ICU length of stay were reduced with rFVIIa use when compared to usual … The RBC transfusion requirements were significantly reduced in the rFVIIa group, as was the operating … These suggested a possible reduced rate of ARDS, most likely to be present in cases of blunt trauma,

55. Refining Key Questions: Interactive Case Study Quiz
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rfviia.pptx
    May 01, 2010 - While the large Mayer 2005 study reported a significant dose-response effect of reduced hematoma growth … There was a trend across studies toward reduced RBC transfusion requirements with rFVIIa use vs. usual … Neither operating room time nor ICU length of stay were reduced with rFVIIa use when compared to usual … The RBC transfusion requirements were significantly reduced in the rFVIIa group, as was the operating … These suggested a possible reduced rate of ARDS, most likely to be present in cases of blunt trauma,

56. PULMONARY with "Discussions" in Exec Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1512.pdf
    December 01, 2015 - asthma exacerbations and reduced need for treatment with systemic glucocorticoids. … Pirfenidone reduced the decline in the 6-minute walk distance and improved progression- free survival … asthma exacerbations and reduced need for treatment with systemic glucocorticoids.35,36 In clinical … Exacerbations necessitating an emergency department visit or hospitalization were reduced by 32% in … During the mepolizumab treatment period, corticosteroid dose was systematically reduced, depending

57. Dementia-Agitation-Aggression Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-agitation-aggression_research-protocol.pdf
    November 13, 2014 - explain the etiology of behavioral disorders in those with dementia: biologic/genetic, behavioral, reduced … The reduced stress threshold model states that dementia reduces an individual’s ability to experience … efficacy and high risk for adverse effects including mortality22-24 and their use is associated with reduced … 13, 2014 5 Intervention Type Interventiona Theory of Effect (biologic/genetic, behavioral, reduced … with dementia Intervention Type Interventiona Theory of Effect (biologic/genetic, behavioral, reduced

58. Effectiveness and Safety of Bronchial Thermoplasty in Management of Asthma: Evidence Summary (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
    December 01, 2017 - Similarly, rates of mild exacerbations were reduced following BT (low SOE), but concerns about the … However, reduced risk of severe exacerbations was suggested (low SOE), although the clinical importance

59. CARDIOVASCULAR (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cardiovascular-horizon-scan-high-impact-1412.pdf
    December 01, 2014 - By week 56, LDL-C concentrations were reduced by 44% (95% confidence interval [CI], -57% to -31%; p … At week 78, LDL-C concentrations were reduced by 38% (-52% to -24%; p<0.0001). … These results were consistent with outcomes of a subgroup of 25 patients with severely reduced LVEF … Lomitapide reduced LDL-C concentrations by a mean of 50% at 26 weeks from baseline. … At week 78, LDL-C concentrations were reduced by 38% (-52 to -24; p<0.0001).

60. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0174_10-20-2009.pdf
    January 01, 2009 - daily living, walking on different surfaces/terrains, quality of life, decreased disability, and reduced