-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin-future_research.pdf
August 01, 2014 - between reduced antibiotic use and antibiotic-
associated adverse events) and predict the
consequences … efficacy as an existing treatment strategy
but may offer other benefits such as fewer side effects and reduced … Simulation models
assume statistical association (e.g. between reduced
antibiotic use and antibiotic-associated
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
December 31, 2013 - Both
options equally and significantly reduced fasting and postprandial glucose
levels (p = 0.05). … Baseline body weight was reduced by 1.6 kg in each
group. … Liraglutide only: Liraglutide (1.2 and 1.8 mg/day) reduced
HbA1c (baseline, 8.4% ± 0.8% and 8.4% ± 0.7% … Slightly higher rates of urinary tract infections
and adverse events related to osmotic diuresis and reduced … subjects with
inadequately
controlled diabetes 26 weeks
Change in
HbA1c
HbA1c significantly reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - studies consistently find that an intervention
improves an outcome (e.g., apnea-hypopnea index is reduced … Overall, intervention A reduced the severity
of [disease] more than intervention B
Low
(improved … Moderate
(reduced
pain)
Low (0.5
difference
in pain
reduction)
Sexual
dysfunction
RCT: 3 ( … Disease]
Low
RCT: 3
(110)
Mediumb Direct Consistent Imprecisec Suspectedd None Intervention A
reduced … Other concerns: None
Intervention A reduced the severity of [disease] more than intervention B.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout-management-disposition-160721.pdf
March 15, 2016 - We agree that lowering of SUA would have
reduced gout attacks, based on some
evidence although this … The text of the results says that "in
study completers, the mean number of self-
reported attacks reduced … So 4 attacks per year reduced to 2.4
attacks per year, and unfortunately no
statistical testing was … moderated (this is mitigated by appropriate prophylaxis); the reason that a strong
demonstration of reduced … • Of the 14 patients in group C, 7 patients with reduced tophi on physical examination
had mean sUA
-
effectivehealthcare.ahrq.gov/products/n-1-trials/research-2014
-
effectivehealthcare.ahrq.gov/products/deprescribing-mhs4/rapid-research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
September 01, 2010 - Selection of
candidates for
therapy
2, 3, 4
Improved mortality
• Breast cancer
• All-cause
Reduced … tamoxifen inhibits MCF-7 breast cancer
xenografts in nude mice through elevated
apoptosis and reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-risk-reduction_research.pdf
October 25, 2010 - 5
Selection of
candidates for
therapy
2, 3, 4
Improved mortality
• Breast cancer
• All-cause
Reduced … with
tamoxifen inhibits MCF-7 breast cancer
xenografts in nude mice through elevated
apoptosis and reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_executive.pdf
November 01, 2012 - Cost-Effectiveness, ROI)
KQ1b
Characteristics of QI Strategy
• Type
• Duration
• Setting
• Other
KQ1
Outcomes:
• Reduced … strategies to reduce HAI, studies
need to demonstrate a causal linkage between improved
adherence and reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
October 05, 2015 - various alternatives to seclusion and
restraints.7 Benefits of seclusion and restraints can include reduced … KQs 1a and 1c only: Reduced use of seclusion or restraints (decreased
rate, amount, or duration)
− … Reduced!use!of!
seclusion!or!restraints!(decreased!
rate,!amount,!or!duration)!
-! Other!
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-13121.pdf
December 05, 2013 - could be offset by reductions in the numbers of patients requiring revision
surgery after ACDF or in reduced … Additional clinical
5
evidence of improved outcomes and reduced costs of care could increase … However, these costs could be offset by
improved surgical outcomes, reduced complications, shorter … hospital stays, a shorter course of
physical therapy, and reduced need for revision surgery. … demands could be offset by the many of same factors that could
reduce costs—improved surgical outcomes, reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/crosscutting-horizon-scan-high-impact-1312.pdf
December 01, 2013 - Experts suggested a positive disruption in care could result from senior-specific EDs
including reduced … The potential for cost savings from reduced hospital readmissions would be the greatest area for
potential … They cited reduced lengths of stay,
more appropriate hospital admissions, and improved diagnoses as … Some experts
thought these costs would be offset by reduced readmissions, reduced adverse events (e.g
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1306.pdf
June 01, 2013 - could be offset by reductions in the numbers of patients requiring revision
surgery after ACDF or in reduced … Additional clinical
5
evidence of improved outcomes and reduced costs of care could increase … However, these costs could be offset by
improved surgical outcomes, reduced complications and length … of stay, shorter duration of physical
therapy, and reduced need for revision surgery. … However, these demands could be offset by improved surgical outcomes, reduced
patient stays and complications
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
May 01, 2013 - for improved health outcomes, including but not
limited to: complete wound healing, healing time,
reduced … for
improved health outcomes, including but not limited to: complete wound healing, healing time, reduced … for
improved health outcomes, including but not limited to: complete wound healing, healing time, reduced … for
improved health outcomes, including but not limited to: complete wound healing, healing time, reduced … Light therapy (wound surface
area reduction)
Low Light therapy reduced wound surface area over time
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
April 01, 2013 - United
Kingdom returning military service members (insufficient
SOE).28
One trial reported that PE reduced … use of the rule, in concert with
an intervention to reduce the incidence of PTSD, results
14
in reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-196-evidence-summary-immunotherapy-asthma.pdf
March 01, 2018 - Our prior
evidence report examined SLIT in aqueous form only,
and concluded that SLIT reduced asthma
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - increase in
stroke/systemic embolism but no statistically
significant difference in bleeding with reduced … dose
vs standard dose apixaban in patients without a
renal indication for reduced dosing; in the same … analysis, there was no difference in the benefit :
risk of reduced dose vs. standard dose rivaroxaban … I think it would be worth noting that all of the
newer agents reduced the risk of hemorrhagic
stroke … This summary states that in the
third study dabigatran reduced
stroke in diabetic patients which
was
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - Cold therapy was associated with reduced use of oxycodone 5 mg at day 1 (18% vs.
52%) and day 6 (11% … Reduced pain and opioid use in the early
postoperative period in patients undergoing
a frontotemporal … A randomized controlled noninferiority
trial of reduced vs routine opioid
prescription after prolapse … Examining reduced opioid prescriptions
after gynecologic laparoscopy: a randomized
controlled trial … Reduced opioid use among patients who
received liposomal bupivacaine for ACL
reconstruction.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-evidence-summary-corticosteroids-asthma.pdf
October 01, 2017 - Intermittent Inhalded Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma
Comparative Effectiveness Review
Number 194
Intermittent Inhaled Corticosteroids and Long-Acting
Muscarinic Antagonists for Asthma
Executive Summary
Objectives and Rationale for the
Review
This report summarizes a systemati…
-
effectivehealthcare.ahrq.gov/products/depression-treatment-ssri/research-protocol