-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
October 14, 2011 - Long-term health outcomes (clinical utility), including reduced mortality/ morbidity and
improved … Long-term health outcomes (clinical utility), including reduced mortality/ morbidity, improved
quality … The outcomes of
interest include reduced mortality/morbidity, improved quality of life, and the potential … Long-term health outcomes of interest, including reduced morbidity/mortality, improved
quality … study populations with cancer that is harder to detect
(missed in prior screening) and may yield a reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
February 01, 2012 - with PKU are also suscep-
tible to other adverse outcomes, includ-
ing impaired executive function, reduced … Phe levels were reduced by at least 30 percent (the
level used in studies submitted to the FDA to assess … In the other uncontrolled open-label trial,58
BH4 (7 to 20 mg/kg/day) was associated with reduced Phe … Phe levels were reduced by at least
30 percent (the usual research target) in up to half of
treated … small studies (total number of
participants, only 47), and there is no evidence that Phe
levels were reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
May 01, 2019 - Multiple births were reduced given LOD
(moderate SOE). … use of single-
embryo transfer is associated with slightly
lower live birth rates but significantly reduced … (1 study)
Pregnancy
complications:
Miscarriage
1 RCT80
(1508)
Reduction: Miscarriages were
reduced … use of single-
embryo transfer is associated with slightly
lower live birth rates but significantly reduced … SOE was reduced
because of quality of included
studies and imprecision of
findings.
-
effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
January 01, 2012 - effective noninvasive therapies for UC, a chronic illness that can lead to lifelong morbidity and
reduced … Achalasia is characterized by prolonged occlusion of the lower esophageal sphincter (LES) and
reduced … series of patients with achalasia treated with POEM (n=56), symptoms of
dysphagia were significantly reduced … Additionally, after 12
months of treatment with teduglutide, 53% of patients reduced their infusion … days per week, and
24% of patients reduced their infusion days per week by 3 or more days.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
June 01, 2013 - For all study
designs, the strength of evidence would be reduced by
one level if there was high risk … SOE was reduced by one level each based on the high risk
of bias, unknown consistency, and imprecision … SOE was reduced by one level each based on the high risk
of bias, unknown consistency, and imprecision … SOE was reduced by two levels based on very serious
risk of bias, by one level for unknown consistency … SOE was reduced by two
levels based on very serious risk of bias and by one level
each for unknown
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_executive.pdf
April 28, 2010 - Important social, occupational, or recreational activities are given up or reduced because
of alcohol … alcohol misuse followed by a behavioral counseling intervention, with or
without referral, leads to reduced … morbidity, reduced mortality, or changes in other long-term (6 months or longer) outcomes
(e.g., health … morbidity,
reduced mortality, or changes in other long-term
(6 months or longer) outcomes? … The control groups
in the included studies generally reduced alcohol
consumption.
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1506.pdf
October 01, 2015 - In June 2014, analysts predicted the cost for
lumacaftor/ivacaftor might be reduced to $150,000 to … Pirfenidone treatment reduced the decline in the 6-minute walk
distance and improved progression-free … published in June 2014, analysts reportedly
predicted the cost for lumacaftor/ivacaftor could be reduced … or who had a decline of 10 percentage points or more in predicted forced vital capacity
(FVC) was reduced … management: Patient length of stay and staff
needed for treating transplant complications could be reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
May 01, 2024 - The rate
of post-operative C. difficile colitis was reduced from 9.4 percent in patients treated
from … ASC resulted in reduced rates of
CRE colonization and infection. … of MRSA examined universal ASC and
did not identify benefit, two of the three studies that reported reduced … Reduced Clostridioides difficile infection in a
pragmatic stepped-wedge initiative using
admission … infection
vs. 4 patients (2.0%)
in single screening
group)
• Weekly screening
associated with
reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_executive.pdf
January 01, 2010 - This strategy of cervical preparation,
or “ripening,” reduced cesarean births by 31 percent. … Three labor management strategies that
significantly reduced the use of cesarean in individual
studies … use during
pushing, or a single intravenous dose of propranolol given
after admission, did not show reduced … This means that studies with some deficiencies did not
demonstrate reduced use of cesarean, but future
-
effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
October 01, 2007 - gastrointestinal (GI) bleeding.9 Its ap-
plicability to our 60-year-old hypertensive patient may be
reduced … aspirin had no effect on cardiovascular risk in women in her
age category (age 55–64), it significantly reduced … Individual RCT26 Over 5 yr, aggregate risk of ipsilateral stroke or
death reduced 53%; benefit lower
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
August 23, 2012 - Because of the narrowly framed key questions, the number
of publications available to analyze was reduced … The SFLC assay was useful for quantitative monitoring of
oligosecretory plasma cell disorders and reduced … The SFLC assay was useful for quantitative monitoring of
oligosecretory plasma cell disorders and reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
July 10, 2023 - intensity of
some genitourinary symptoms increase with advancing age.5, 6 GSM may be associated
with reduced … GSM are also associated with other common urinary
2
conditions in older women, such as reduced … identification, evaluation, and treatment of
these symptoms complex.2 A causal relationship between reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
April 10, 2025 - They
found that DBT compared to TAU reduced suicide
attempts and incidents of NSSI which is mentioned … but
they also found that DBT reduced restraints and
seclusions which are largely enacted due to suicidal … thoughts and behaviors and reduced need for constant
observation for suicidal ideation and NSSI. … Given that none of the
safety planning
interventions were
associated with reduced
SI/SA outcomes, … Moreover,
CBT trials find that treatment is associated with reduced
suicidal ideation and attempts
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
January 01, 2015 - Robust studies measuring outcomes such as reduced
admissions, reduced returns to the ED, and reduced … After 20 years, annual HIV
incidence could be reduced by 17%, 37%, and 60% if 20%, 50%, and 100% of … Lorcaserin
was FDA approved for use with a reduced-calorie diet and increased physical activity for … We expect that
these costs would be offset by decreased costs from reduced emergency room visits and … However, these costs might be offset by
reduced admissions and return visits to the ED, reduced adverse
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
August 01, 2016 - stroke; the acceptable
macronutrient distribution range (a range of intakes that
is associated with reduced … In contrast, one of three studies found an
association of higher intake with reduced risk of CVD
death … ; one of two studies found a significant association
of higher intake with reduced risk of MI death; … Two studies both found significant associations between
higher ALA intake and reduced all-cause death … However, a possible pattern could
be discerned such that higher doses of 3.4 or 4 g/d
reduced Tg by
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_executive.pdf
September 01, 2012 - blood pressure
for case management and face-to-face education with
pharmacists for hypertension; reduced … All five studies evaluated policy-level interventions that
reduced patient out-of-pocket expenses for … prescription
medications, either through reduced medication
copayments or improved prescription drug … adherence to medications
used to treat diabetes favoring the group that had out-
of-pocket expenses reduced … We found the strongest evidence for enhancing adherence
with reduced copays across clinical conditions
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
January 01, 2020 - ................................................................................8
Final Ranking of Reduced … prioritization included three iterative steps: initial voting, initial ranking, and
final ranking of reduced … Stakeholders
snowball the list
(Teleconference and
Web-based Survey)
9
Final Ranking of Reduced … List of Items
We then sent the reduced list of 16 future research questions and seven methodologic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
September 01, 2017 - However, there was a trend towards
reduced daily consumption on baclofen. … However, at 13
months, nalmefene significantly reduced the
number of heavy drinking days over placebo … study of oral naltrexone vs. placebo for HIV-
infected women (n=17) demonstrated feasibility,
and reduced … Heavy drinkers (n=41) with a standing
dBP >=80 mmHg showed reduced drinks per week
and heavy drinking … Varenicline also
reduced consumption more than placebo for those
who were older (age >45), had longer
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
October 01, 2016 - alternative strategies or usual care
(KQ 2a)
Intermediate Outcomes
• Decreased aggression
• Reduced … Intermediate Outcomes
• Decreased aggression
Intermediate Outcomes
• Decreased aggression
• Reduced … frequency, severity, or duration (measured
by either direct counts or validated aggression scales) or
(2) reduced … risk of
bias, consistency
unknown—single
study, direct, precise
No significant difference for
any reduced … number of risk assessment
interventions subsequently led to less aggressive behavior
(low SOE) and reduced
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
December 31, 2022 - We found that prior infection with the Alpha variant or the wild-type SARS-CoV-2
virus reduced the risk … similar protection against reinfection
by the Delta variant as was found in our previous report (80–97% reduced … analysis of severity, from the United
Kingdom, found that, for unvaccinated individuals, prior infection reduced … 0.57).41 For vaccinated individuals, prior infection had no effect on the
risk of hospitalization but reduced … Seropositivity at baseline also reduced the incidence of symptoms associated with COVID-19,
such as