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Showing results for "reduced".

  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
    October 14, 2011 -  Long-term health outcomes (clinical utility), including reduced mortality/ morbidity and improved …  Long-term health outcomes (clinical utility), including reduced mortality/ morbidity, improved quality … The outcomes of interest include reduced mortality/morbidity, improved quality of life, and the potential …  Long-term health outcomes of interest, including reduced morbidity/mortality, improved quality … study populations with cancer that is harder to detect (missed in prior screening) and may yield a reduced
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
    February 01, 2012 - with PKU are also suscep- tible to other adverse outcomes, includ- ing impaired executive function, reduced … Phe levels were reduced by at least 30 percent (the level used in studies submitted to the FDA to assess … In the other uncontrolled open-label trial,58 BH4 (7 to 20 mg/kg/day) was associated with reduced Phe … Phe levels were reduced by at least 30 percent (the usual research target) in up to half of treated … small studies (total number of participants, only 47), and there is no evidence that Phe levels were reduced
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-217-infertility-evidence-summary.pdf
    May 01, 2019 - Multiple births were reduced given LOD (moderate SOE). … use of single- embryo transfer is associated with slightly lower live birth rates but significantly reduced … (1 study) Pregnancy complications: Miscarriage 1 RCT80 (1508) Reduction: Miscarriages were reduced … use of single- embryo transfer is associated with slightly lower live birth rates but significantly reduced … SOE was reduced because of quality of included studies and imprecision of findings.
  4. PEPTIC ULCER #11 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/11_peptic_ulcer_potential_high_impact_2012-12-111.pdf
    January 01, 2012 - effective noninvasive therapies for UC, a chronic illness that can lead to lifelong morbidity and reduced … Achalasia is characterized by prolonged occlusion of the lower esophageal sphincter (LES) and reduced … series of patients with achalasia treated with POEM (n=56), symptoms of dysphagia were significantly reduced … Additionally, after 12 months of treatment with teduglutide, 53% of patients reduced their infusion … days per week, and 24% of patients reduced their infusion days per week by 3 or more days.
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_executive.pdf
    June 01, 2013 - For all study designs, the strength of evidence would be reduced by one level if there was high risk … SOE was reduced by one level each based on the high risk of bias, unknown consistency, and imprecision … SOE was reduced by one level each based on the high risk of bias, unknown consistency, and imprecision … SOE was reduced by two levels based on very serious risk of bias, by one level for unknown consistency … SOE was reduced by two levels based on very serious risk of bias and by one level each for unknown
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_executive.pdf
    April 28, 2010 - Important social, occupational, or recreational activities are given up or reduced because of alcohol … alcohol misuse followed by a behavioral counseling intervention, with or without referral, leads to reduced … morbidity, reduced mortality, or changes in other long-term (6 months or longer) outcomes (e.g., health … morbidity, reduced mortality, or changes in other long-term (6 months or longer) outcomes? … The control groups in the included studies generally reduced alcohol consumption.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1506.pdf
    October 01, 2015 - In June 2014, analysts predicted the cost for lumacaftor/ivacaftor might be reduced to $150,000 to … Pirfenidone treatment reduced the decline in the 6-minute walk distance and improved progression-free … published in June 2014, analysts reportedly predicted the cost for lumacaftor/ivacaftor could be reduced … or who had a decline of 10 percentage points or more in predicted forced vital capacity (FVC) was reduced … management: Patient length of stay and staff needed for treating transplant complications could be reduced
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs4-active-infection-rapid-response.pdf
    May 01, 2024 - The rate of post-operative C. difficile colitis was reduced from 9.4 percent in patients treated from … ASC resulted in reduced rates of CRE colonization and infection. … of MRSA examined universal ASC and did not identify benefit, two of the three studies that reported reducedReduced Clostridioides difficile infection in a pragmatic stepped-wedge initiative using admission … infection vs. 4 patients (2.0%) in single screening group) • Weekly screening associated with reduced
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cesarean-birth-2010_executive.pdf
    January 01, 2010 - This strategy of cervical preparation, or “ripening,” reduced cesarean births by 31 percent. … Three labor management strategies that significantly reduced the use of cesarean in individual studies … use during pushing, or a single intravenous dose of propranolol given after admission, did not show reduced … This means that studies with some deficiencies did not demonstrate reduced use of cesarean, but future
  10. S16 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
    October 01, 2007 - gastrointestinal (GI) bleeding.9 Its ap- plicability to our 60-year-old hypertensive patient may be reduced … aspirin had no effect on cardiovascular risk in women in her age category (age 55–64), it significantly reduced … Individual RCT26 Over 5 yr, aggregate risk of ipsilateral stroke or death reduced 53%; benefit lower
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/plasma-cell-dyscrasias-sflc-assay_disposition-comments.pdf
    August 23, 2012 - Because of the narrowly framed key questions, the number of publications available to analyze was reduced … The SFLC assay was useful for quantitative monitoring of oligosecretory plasma cell disorders and reduced … The SFLC assay was useful for quantitative monitoring of oligosecretory plasma cell disorders and reduced
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
    July 10, 2023 - intensity of some genitourinary symptoms increase with advancing age.5, 6 GSM may be associated with reduced … GSM are also associated with other common urinary 2 conditions in older women, such as reduced … identification, evaluation, and treatment of these symptoms complex.2 A causal relationship between reduced
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-youth-disposition-comments.pdf
    April 10, 2025 - They found that DBT compared to TAU reduced suicide attempts and incidents of NSSI which is mentioned … but they also found that DBT reduced restraints and seclusions which are largely enacted due to suicidal … thoughts and behaviors and reduced need for constant observation for suicidal ideation and NSSI. … Given that none of the safety planning interventions were associated with reduced SI/SA outcomes, … Moreover, CBT trials find that treatment is associated with reduced suicidal ideation and attempts
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/horizon-scan_research-2015.pdf
    January 01, 2015 - Robust studies measuring outcomes such as reduced admissions, reduced returns to the ED, and reduced … After 20 years, annual HIV incidence could be reduced by 17%, 37%, and 60% if 20%, 50%, and 100% of … Lorcaserin was FDA approved for use with a reduced-calorie diet and increased physical activity for … We expect that these costs would be offset by decreased costs from reduced emergency room visits and … However, these costs might be offset by reduced admissions and return visits to the ED, reduced adverse
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/fatty-acids-cardiovascular-disease_executive.pdf
    August 01, 2016 - stroke; the acceptable macronutrient distribution range (a range of intakes that is associated with reduced … In contrast, one of three studies found an association of higher intake with reduced risk of CVD death … ; one of two studies found a significant association of higher intake with reduced risk of MI death; … Two studies both found significant associations between higher ALA intake and reduced all-cause death … However, a possible pattern could be discerned such that higher doses of 3.4 or 4 g/d reduced Tg by
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/medication-adherence-interventions_executive.pdf
    September 01, 2012 - blood pressure for case management and face-to-face education with pharmacists for hypertension; reduced … All five studies evaluated policy-level interventions that reduced patient out-of-pocket expenses for … prescription medications, either through reduced medication copayments or improved prescription drug … adherence to medications used to treat diabetes favoring the group that had out- of-pocket expenses reduced … We found the strongest evidence for enhancing adherence with reduced copays across clinical conditions
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
    January 01, 2020 - ................................................................................8 Final Ranking of Reduced … prioritization included three iterative steps: initial voting, initial ranking, and final ranking of reduced … Stakeholders snowball the list (Teleconference and Web-based Survey) 9 Final Ranking of Reduced … List of Items We then sent the reduced list of 16 future research questions and seven methodologic
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
    September 01, 2017 - However, there was a trend towards reduced daily consumption on baclofen. … However, at 13 months, nalmefene significantly reduced the number of heavy drinking days over placebo … study of oral naltrexone vs. placebo for HIV- infected women (n=17) demonstrated feasibility, and reduced … Heavy drinkers (n=41) with a standing dBP >=80 mmHg showed reduced drinks per week and heavy drinking … Varenicline also reduced consumption more than placebo for those who were older (age >45), had longer
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/aggression_executive.pdf
    October 01, 2016 - alternative strategies or usual care (KQ 2a) Intermediate Outcomes • Decreased aggression • Reduced … Intermediate Outcomes • Decreased aggression Intermediate Outcomes • Decreased aggression • Reduced … frequency, severity, or duration (measured by either direct counts or validated aggression scales) or (2) reduced … risk of bias, consistency unknown—single study, direct, precise No significant difference for any reduced … number of risk assessment interventions subsequently led to less aggressive behavior (low SOE) and reduced
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
    December 31, 2022 - We found that prior infection with the Alpha variant or the wild-type SARS-CoV-2 virus reduced the risk … similar protection against reinfection by the Delta variant as was found in our previous report (80–97% reduced … analysis of severity, from the United Kingdom, found that, for unvaccinated individuals, prior infection reduced … 0.57).41 For vaccinated individuals, prior infection had no effect on the risk of hospitalization but reduced … Seropositivity at baseline also reduced the incidence of symptoms associated with COVID-19, such as

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