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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-evidence-summary.pdf
    June 01, 2022 - visit versus traditional visit schedules for routine antenatal care o Studies comparing reduced routine …  Barriers from both patient and provider perspectives: reduced visits may lead to important gaps …  Facilitators from provider perspective: reduced visits align with midwifery philosophies of care …  Barriers from provider perspective: reduced visits may compromise patients’ antenatal care and … Providers also expressed fears that reduced care may lead to staff cutbacks.
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-research-executive-summ.pdf
    March 01, 2025 - Childhood cancer Approximate 10% to 23% reduced risk of childhood leukemia with ever versus never … Low SOE for reduced risk Respiratory infections Potential reduced risk of more severe respiratory … Allergic rhinitis Potential reduced risk of allergic rhinitis associated with more breastfeeding. … Malocclusion Potential reduced risk of malocclusion associated with any or exclusive breastfeeding, … Type 1 diabetes Potential reduced risk of type 1 diabetes in children ≤18 years associated with “
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-271-mental-health-pregnant-executive-summary.pdf
    July 01, 2024 - TAU Depressive disorders Reduced anxiety symptoms CBT more effective SMD −0.55 (−0.67, −0.44) … TAU Depressive disorders Reduced anxiety symptoms IPT more effective SMD -0.73 (−1.19, −0.26) … TAU Depressive disorders Reduced depressive symptoms Behavioral activation more effective … TAU Depressive disorders Reduced depressive symptoms No conclusions SMD −0.25 (−0.53, 0.02 … placebo light therapy Depressive disorders Reduced depressive symptoms No conclusions SMD
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_policymaker.pdf
    August 01, 2016 - The rate of preventable readmissions may be reduced by transitional care interventions, which are defined … üüMultidisciplinary-HF clinic-based interventions reduced all-cause readmissions and mortality but … 9 ��� HF-specific readmission 1 282 Reduced 7 ��� Composite endpoint** 4 824 Reduced 10 ��� Mortality … 8 1,693 Reduced 33 ��� Number of hospital days at readmission 3 403 Reduced NA ��� Structured telephone … support All-cause readmission 8 2,166 No benefit NA ��� HF-specific readmission 7 1,790 Reduced 14
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
    March 01, 2016 - While procalcitonin point-of-care testing reduced antibiotic prescribing in adults, use of an adult … Delayed prescribing reduced antibiotic prescribing but also reduced patient satisfaction and increased … Clinical Interventions (Point-of-Care Testing): ��Procalcitonin point-of-care testing in adults reduced … ��Streptococcal antigen point-of-care testing (rapid strep testing) reduced overall prescribing by 20 … ��Delayed prescribing reduced patient satisfaction (���), increased persistence of moderate to severe
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_policymaker.pdf
    August 01, 2016 - Health care utilization studies* report reduced medical costs among patients treated with AUD medication … by naltrexone ��� Return to heavy drinking 19 2,875 Reduced by naltrexone ��� Percentage of drinking … days 15 1,992 Reduced by naltrexone ��� Percentage of heavy drinking days 6 521 Reduced by naltrexone … by naltrexone ��� Topiramateb vs. placebo Percentage of drinking days 2 521 Reduced by topiramate � … �� Percentage of heavy drinking days 2 521 Reduced by topiramate ��� Number of drinks per drinking
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0647-13114.pdf
    June 21, 2013 - Outcome(s): Improvement in symptoms of depression; reduced suicide risk; improved social and occupational … functioning; improved health-related quality of life; improved treatment adherence; reduced side effects … MDD is associated with reduced adherence to medical treatment, reduced participation in preventive activities
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
    January 01, 2012 - • ACEI significantly reduced ESRD risk in patients with overt proteinuria. … • ACEI significantly reduced risk of composite renal outcome in one of three trials. … • In one trial, ACEI significantly reduced risk of composite renal outcome. … • CCB significantly reduced risk of MI. … • High-dose statin significantly reduced risk of CHF hospitalization and reduced risk of all composite
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
    October 01, 2012 - ESRD was not significantly reduced in patients with CKD stages 1–3 who did not have proteinuria. … ESRD was not significantly reduced in patients with CKD stages 1–3 who did not have proteinuria. … proteinuria to 1.44 (1-07-1.93) g/day (P=0.003), addition of a LSD reduced it to 0.85 (0.66-1.10) … g/day (P<0.001) and addition of ARB + LSD reduced it to 0.67 (0.50-0.91) g/day (P<0.001). … ESRD was not significantly reduced in patients with CKD stages 1–3 who did not have proteinuria.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
    February 01, 2024 - number of medications • 1 study reduced dose of meds • 1 study reduced ED visits; no difference … PIMs (OR 0.41; 95% CI 0.19- 0.89) • reduced mortality (OR 0.90; 95% CI 0.82-0.99) • trend to … reduced falls (OR 0.85; 95% CI 0.73-1.00) • no difference in hospitalization Lee, 202232 16 … number of medications • 1 of 3 reduced hospital readmissions • no difference in mortality, … reduced falls • 1 study reduced medication costs • 1 of 2 reduced total costs Reviews Based
  11. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
    February 01, 2016 - -0.04 (-0.11 to 0.03) NA ��� Naltrexone 50 mg oral vs. placebo Return to any drinking 16 2,347 Reduced … by naltrexone RD: -0.05 (-0.10 to -0.00) 20 ��� Return to heavy drinking 19 2,875 Reduced by naltrexone … RD: -0.09 (-0.13 to -0.04) 12 ��� Percentage of drinking days 15 1,992 Reduced by naltrexone WMD: … -5.4 (-7.5 to -3.2) NA ��� Percentage of heavy drinking days 6 521 Reduced by naltrexone WMD: -4.1 … WMD: -11.5 (-18.3 to -4.8) NA ��� Number of drinks per drinking day 2 521 Reduced by topiramate WMD
  12. S143 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
    October 01, 2007 - Matching was performed at random, and with propensity scores that incorporated a reduced or expanded … However, matching on a propensity score created on a reduced set of variables yielded a result that suggested … The first set of propensity models (based on a reduced set of variables) was highly predictive of statin … Statin Initiators and Matched Comparators (Reduced Model) No. … This process improved the internal validity of the comparison, but it came at the cost of reduced gener
  13. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
    September 01, 2009 - 5 Selection of candidates for therapy 2, 3, 4 Improved mortality • Breast cancer • All-cause Reduced … • Tamoxifen (RR 0.58; 0.42, 0.79; four trials) and raloxifene (RR 0.33; 0.18, 0.61; two trials) reduced … trials, raloxifene (RR 0.61; 0.54, 0.69; two trials) and tibolone (RR 0.55; 0.41. 0.74; one trial) reduced … nonvertebral fractures; and tibolone reduced wrist (RR 0.54; 0.35, 0.82; one trial) but not hip fractures … Summary of primary prevention trials — benefits: number of events reduced with medications and strength
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-nomination-140925.pdf
    March 20, 2014 - intervention followed by surgery) lead to improved health-related quality of life, decreased disability, reduced … and postoperative rehabilitation on improved health-related quality of life, decreased disability, reduced … effectiveness of non-operative interventions on improved health-related quality of life, decreased disability, reduced … with non-operative treatment lead to improved health-related quality of life, decreased disability, reduced
  15. effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-stone-prevention_executive.pdf
    March 01, 2013 - Composite: Reduced risk (20 vs. 38%; RR, 0.52 [CI, 0.29 to 0.95]). … Composite: Reduced risk (6 vs. 19%; RR, 0.32 [CI, 0.14 to 0.74]). … Composite: No reduced risk (48 vs. 48%; RR, 1.00 [CI, 0.52 to 1.91]). … Composite: No reduced risk (63 vs. 48%; RR, 1.18 [CI, 0.66 to 2.12]). … Composite: No reduced risk (29 vs. 45%; RR, 0.65 [CI, 0.37 to 1.16]).
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-fracture-prevention-evidence-summary.pdf
    April 01, 2019 - In older women with osteopenia or osteoporosis, 6 years of zoledronate versus placebo reduced incident … alendronate versus placebo, but women with osteopenia had no reduced risk (p-value for interaction … vertebral and nonvertebral fractures in women with osteoporosis, and zoledronate for 6 years reduced … In women with osteoporosis, long-term raloxifene for 4 years reduced incident vertebral fractures, … In women with unknown osteoporosis or osteopenia status, oral hormone therapy for 5-7 years reduced
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0398_06-17-2008.pdf
    January 01, 2008 - cost; patient-centered outcomes related to optimal treatment of ESA or iron therapy including 1) reduced … mortality, 2) reduced morbidity, 3) reduced adverse events, and 4) improved quality-of-life.
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_executive.pdf
    May 01, 2014 - STS reduced HF- specific readmission rates (high SOE) but not all-cause readmission (moderate SOE). … We found no single-component intervention that reduced all-cause readmissions. … Three categories of interventions reduced mortality rates over 3 to 6 months: home-visiting programs … The two categories of interventions that reduced all-cause readmissions and mortality (home-visiting … all-cause readmissions and mortality; STS reduced HF- specific readmissions and mortality.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0663-131114.pdf
    April 10, 2013 - Improvement in symptoms of manic, mixed, or depressive episodes; prevention of recurrent bipolar episodes; reduced … functioning; improved health-related quality of life; remission of co-occurring substance use disorder; reduced
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0313_02-09-2009.pdf
    January 01, 2009 - recurrence Comparator(s): No treatment/other treatments Outcome(s): Prevention of stone recurrence, reduced … dietary habits (increasing/decreasing intake of certain minerals, decreasing animal protein intake, reduced

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