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381. Disposition of Comments for Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer: An Update of a 2008 Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer-therapies-update_disposition-comments.pdf
     December 16, 2014 - report does not give sufficient consideration to the limitations of screening trials on which their recommendations … After discussions and recommendations from TEP members, we decided to include and focus only on men … After discussions and recommendations from TEP members, we decided to include and focus only on men … Conclusions are appropriate and useful, given the lack of information upon which to make recommendations … I believe there are some misinterpretations of findings as noted below as well as recommendations for

382. genetic-testing-developmental-disabilities-protocol-140930 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/genetic-testing-developmental-disabilities_research-protocol.pdf
     September 30, 2014 - What recommendations do clinical practice guidelines include regarding the use of the tests? c. … See above Recommendations in Clinical Guidelines Describe any relevant recommendations in clinical … American College of Medical Genetics recommendations for the design and performance expectations for … Array-based technology and recommendations for utilization in medical genetics practice for detection … Current recommendations for the molecular evaluation of newly diagnosed holoprosencephaly patients.

383. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay_research-protocol.pdf
     May 02, 2011 - However, these guidelines were not based on a systematic review, and the recommendations they made were … In: NACB: practice guidelines and recommendations for use of tumor markers in the clinic. … Systems for grading the quality of evidence and the strength of recommendations I: critical appraisal

384. Disposition of Comments Report for CER 226: Labor Dystocia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
     May 14, 2020 - Results Peer Reviewer #3 I would consider adding to the recommendations/areas for future research that … This review does not speak to the length of labor and/or current recommendations/guidelines regarding

385. Disposition of Comments Report for Treatment of Atrial Fibrillation (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
     June 28, 2013 - This has not been shown to have an effect on patient outcomes and all the recommendations base rhythm … This has not been shown to have an effect on patient outcomes and all the recommendations base rhythm … report is on the state of the evidence rather than how this evidence is translated in to guideline recommendations … we have not added additional focus on the specific guideline recommendations by key question as suggested … Please address and justify your difference from current guideline recommendations.

386. Disclosure Policy and Form (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/epc-disclosure-policy-form.pdf
     March 01, 2023 - Disclosure Policy and Form AHRQ Evidence-based Practice Center Policy on Financial and Nonfinancial Interests Background and Purpose of Policy To maintain public confidence in the scientific integrity and credibility of work produced by the EPC Program, it is essential that all aspects of the process and metho…

387. Disposition of Comments for Imaging Tests for the Staging of Colorectal Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
     November 20, 2014 - We have added “of average-risk adults” to clarify that the USPSTF recommendations do not address higher … In providing this type of detail it would be easier to implement these recommendations to various groups

388. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - The key implications relate more to future research than any actionable clinical/health policy recommendations … this review, we do not believe the strength of current evidence supports extensive or enthusiastic recommendations … General Public Reviewer Henry Mahncke, Posit Science Finally, the intent of the review is "to make recommendations … The only conclusion possible from the draft review is that there are no such recommendations (I note … General Public Reviewer Henry Mahncke, Posit Science Finally, and most importantly, the recommendations

389. Interventions To Prevent Age-Related Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer’s-Type Dementia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
     March 24, 2017 - The key implications relate more to future research than any actionable clinical/health policy recommendations … this review, we do not believe the strength of current evidence supports extensive or enthusiastic recommendations … General Public Reviewer Henry Mahncke, Posit Science Finally, the intent of the review is "to make recommendations … The only conclusion possible from the draft review is that there are no such recommendations (I note … General Public Reviewer Henry Mahncke, Posit Science Finally, and most importantly, the recommendations

390. DEcIDE 32: The Incident User Design in Comparative Effectiveness Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
     May 01, 2012 - About Medical Device Registry Studies ..............................................................6 Recommendations … Although the recommendations could apply to any non-randomized study—regardless of why the data were … collected—the recommendations are intended for studies conducted with secondary data sources (i.e., … Effective Health Care Program Research Report Number 32 8 Recommendations for Reporting for Sections … Cover Structured Abstract Contents Introduction Recommendations for Reporting for Sections 2

391. Web Interactive Presentation of EPC Reports: A Foray Into Interactive Reports (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-web-interactive-presentation.pdf
     September 01, 2019 - However, systematic review reports, including those by the EPC Program do not provide specific recommendations … For such problems, explicit recommendations are outside the scope of systematic reviews and are not … However, many users seek clinical practice recommendations, especially for controversial topics or topics … describe and summarize the evidence base, but generally refrain from making explicit clinical practice recommendations

392. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
     February 01, 2013 - The following are our recommendations for how to approach selecting studies from gray literature documents

393. Disposition of Comments_Comparative Effectiveness Review No. 271, Treatments for Maternal Mental Health Conditions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-271-mental-health-pregnant-disposition-comments.pdf
     July 31, 2024 - In short, lots of ink and paper to tell us, it is too soon to make any recommendations about effectiveness … This review does not aim to make recommendations about treatment. … Following reviewer and sponsor recommendations, we have removed the yoga studies from exercise analysis

394. Disposition of Comments_Systematic Review: Breastfeeding and Health Outcomes for Infants and Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-disposition-comments.pdf
     March 31, 2025 - on coronavirus disease 2019 (although certainly enough evidence existed to change initial national recommendations … on maternal/infant separation and changing national recommendations did not result in any evidence … critique is that this review missed a tremendous opportunity to explicitly state for researchers the recommendations … While recommendations for how to define and capture the exposures are strongly needed, we believe this … Breastfeeding success is inextricably linked to systemic support, and any public health recommendations

395. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
     January 01, 2015 - for future research and reconsider the very specific recommendations. … I like the research recommendations! Thank you for taking the time to review our report. … This is in contrast with the metformin package insert recommendations to avoid metformin when serum … We are unable to make recommendations to the FDA or others as part of the report; however, the FDA … Recommendations for observational studies for longer term outcomes can be made since we included observational

396. Psychosocial and Pharmacologic Interventions for Disruptive Behavior in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disruptive-behavior-disorders-protocol.pdf
     January 31, 2023 - Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised

397. Menopause-Protocol-130612 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
     June 12, 2013 - risks are few when initiated within a few years of menopause.”28 The NAMS position statement and IMS recommendations … more recent RCTs and observational studies when the GRADE of evidence [according to the Grading of Recommendations … Hormone therapy for the prevention of chronic conditions in postmenopausal women: recommendations from … IMS updated recommendations on postmenopausal hormone therapy. Climacteric. 2007 Jun;10(3):181-94. … recent RCTs and observational studies when the GRADE of evidence [according to the Grading of Recommendations

398. Rapid-Reviews-End-User White-Paper (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-reviews-end-user_white-paper.pdf
     April 01, 2016 - One KI (research funder) mentioned that specific recommendations regarding future research needs … [provider] Future research recommendations Future research recommendations are helpful for “ … …what are the future research recommendations…99.9% of the systematic reviews all 7 Element … studies, the use of evidence and summary tables, strength of evidence assessments, and future research recommendations … Advancing knowledge of rapid reviews: an analysis of results, conclusions and recommendations from

399. Development of a Primary Care Guie for Implementing Evidence-Based Screening and Counseling for Unhealthy Alcohol Use With Epic-Based Electronic Health Record Tools: A Pilot Dissemination Project (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-research-report-unhealthy-alcohol-use-final.pdf
     September 01, 2018 - cause of preventable deaths among working-age adults in the US.4 Despite the burden of illness and recommendations

400. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/genitourinary-symptoms-protocol_0.pdf
     July 10, 2023 - Because this organization uses Grading of Recommendations Assessment, Development and Evaluation (GRADE … of genitourinary syndrome of menopause in women with or at high risk for breast cancer: consensus recommendations … thromboembolism EBT Energy-based treatment EPC Evidence-based Practice Center GRADE Grading of Recommendations