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  1. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/latent-tuberculosis-infection-screening
    May 02, 2023 - Meta-analysis found greater risk for hepatotoxicity with isoniazid than with rifampin (pooled RR, 4.22 … Isoniazid was associated with higher rates of hepatotoxicity than placebo or rifampin. … Studies were excluded if more than 25% of the study population was younger than 18 years or known to … did not enroll populations that were identified to have LTBI via screening in primary care settings; rather … Isoniazid was associated with higher rates of hepatotoxicity than placebo or rifampin.
  2. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breastfeeding-primary-care-interventions
    April 11, 2025 - 3 months, 3 months to less than 6 months, 6 months, and 12 months. … Just more than one-third of studies took place in the United States (33); the remaining studies took … The total duration of interventions also varied widely and ranged from 1 day (1 session) to more than … 3 months, 3 months to less than 6 months, and 6 months ( Table 1 ). … Rather, there was a wide range of approaches that were shown to improve rates of breastfeeding and are
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/dCH2CMqVyAzf4eyj-ch6H3
    August 09, 2016 - through elevated TC and LDL-C concentrations, which can be 2 to 3 times higher in children with FH than … Studies that focused on treating those with secondary dyslipidemia or monogenic dyslipidemia other than … Statins Three of 8 statin trials were longer than 6 months: 2 were of 48 weeks’ duration,25,26 and 1 … adolescents, no such evidence was found.18 When the aim of pharmacologic treatment is reducing disease risk ratherthan treating existing disease, only a low risk of harm is acceptable.
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/UPu84CV2CNuxR8kpVU6e3V
    November 01, 2008 - Results of Base-Case Analysis: Beginning screening at age 50 years was consistently better than at age … efficiency ratio than strat- egies with less intensive (or no) use of noncolonoscopy tests (that is, … The life-years gained for this set of screening strategies is approximately 8% to 12% lower than that … Our analysis used chronologic age rather than comorbidity-adjusted life expectancy, and the deci- sion … In practice, adherence is much lower than 100% and varies across type of screening test.
  5. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary9/alcohol-misuse-screening-and-behavioral-counseling-interventions-in-primary-care-2013
    September 25, 2012 - , 0.12 [CI, 0.07 to 0.16]; 7 trials; 2737 participants), and 11% more adults reported drinking less than … drinking practices (for example, by encouraging fewer drinks per occasion or not drinking before driving) ratherthan to achieve abstinence. … Other than the results for opportunity costs, our results are limited by the few trials that reported … These categories are not all discrete (an individual may meet the definition of more than one).
  6. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-pregnant-women1/human-immunodeficiency-virus-hiv-infection-screening
    June 11, 2019 - women who started ART before pregnancy, continued ART throughout pregnancy, and had a viral load less than … in India and Africa among HIV-infected women (92% breastfeeding) with CD4 cell counts of or greater than … with higher scores on the Wechsler Preschool and Primary Scale of Intelligence III (WPPSI-III) test than … Third, observational studies, which are more susceptible to bias and confounding than well-conducted … Fifth, most studies reported results for individual ART agents and classes rather than for ART regimens
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/MjwZ4vRLZDVUSnfMA6SrDo
    June 01, 2012 - Survey indicated that 30% of women experience physical violence, 9% rape, 17% sexual violence other than … We rated the trial as fair rather than good quality because loss to follow-up was high (43% of screened … intervention group had fewer recurrent episodes of IPV during pregnancy and the postpartum pe- riod than … Women have higher rates of IPV disclosure using self-administered methods rather than face-to-face ques … If results are �0.50, discriminatory accuracy is no better than a coin toss.
  8. www.uspreventiveservicestaskforce.org/uspstf/document/evaluating-test-strategies-for-colorectal-cancer-screening-a-decision-analysis-for-the-us-preventive-services-task-force/colorectal-cancer-screening-2008
    October 15, 2008 - Results of Base-Case Analysis: Beginning screening at age 50 years was consistently better than at age … The life-years gained for this set of screening strategies is approximately 8% to 12% lower than that … As expected, results for the worst-case analysis showed fewer life-years gained than results for the … We note that our analysis used chronologic age rather than comorbidity-adjusted life expectancy and that … In practice, adherence is much lower than 100% and varies across type of screening test.
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/_SBmXPhUQWo-dc85FJ5wHf
    February 01, 2015 - clothing before cuff placement [122, 128, 129]), primarily reported results in terms of mean val- ues ratherthan diagnostic categories or enrolled hy- pertensive populations. … better directed toward improved measurement accuracy and timely measurement in higher-risk persons ratherthan measurement of all persons at every office visit. … Incidence was generally higher in men than women, especially in younger populations.
  10. www.uspreventiveservicestaskforce.org/uspstf/recommendation/high-cholesterol-other-lipid-abnormalities-screening-1996
    January 01, 1996 - C Asymptomatic persons older than age 65 There is insufficient evidence to recommend for or against … high values (>300 mg/dL). 16 Excess risk from high cholesterol is smaller in women, who have less than … 228 mg/dL. 56 Some authorities therefore recommend advising patients of their "cholesterol range," rather … on two occasions has been recommended, and a third if the first two values differ by more than 16%. … The assumption that early treatment is more effective than treatment begun later in life 57 rests on
  11. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary20/suicide-risk-in-adolescents-adults-and-older-adults-screening
    April 15, 2013 - Limitation: Treatment evidence was derived from high-risk rather than screen-detected populations. … It accounted for more than 1.4 million years of potential life lost before age 85 years 3 . … Psychotherapy did not show greater improvement than usual care for suicidal ideation (SMD, −0.10 [CI, … Among psychotherapy studies, we found no clear predictors of effect size other than target age (adults … This trial reported suicide rates per 100,000 persons as its outcome, rather than following an identified
  12. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-aspirin-to-prevent-cardiovascular/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
    April 11, 2016 - Ten trials reported RRs of 0.81 to 0.98, and 1 trial 24 reported an RR greater than 1. … be largely driven by a benefit in participants with diabetes (adjusted RR, 0.46 [CI, 0.25 to 0.85]) ratherthan those without diabetes (adjusted RR, 0.87 [CI, 0.72 to 1.05]). … stroke benefit is not seen with all doses of aspirin, the certainty of the stroke benefit is weaker than … that of the average population or the baseline risk for CVD events is higher than that for the average
  13. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/screening-depression-suicide-risk-adults
    June 20, 2023 - The direct evidence is more equivocal than the indirect evidence, being based on a smaller number of … on the test performance of suicide risk screening instruments; no instrument was addressed in more than … participants; studies were required to have identified participants through outpatient or community settings, rather … participants; studies were required to have identified participants through outpatient or community settings, ratherthan through emergency or inpatient settings Abbreviations: CBT, cognitive behavioral therapy
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/4TToeya43r5Qc5A6TjFGWS
    August 01, 2023 - of participants with prepregnancy diabetes or pregestational obesity for exposures measured as less than … indication of dose response in 3 of 4 studies19,20,22-24; 1 study showed lower odds for daily use vs less than … adjusting for maternal age (aOR, 0.54 [95% CI, 0.29-0.95]).8 Results adjusting for planned pregnancy ratherthan maternal age were similar but not statistically signifi- cant (aOR, 0.57 [95% CI, 0.30-1.02]).8
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/SJbAXUAQTv2GWemMuBab6W
    April 08, 2025 - 3 months, 3 months to less than 6 months, 6 months, and 12 months. … Just more than one-third of studies took place in the United States (33); the remaining studies took … The total duration of in- terventions also varied widely and ranged from 1 day (1 session) to more than … 3 months, 3 months to less than 6 months, and 6 months (Table 1). … Rather, there was a wide range of approaches that were shown to improve rates of breastfeeding and are
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/8dzfZ_s3tZueoEh5Xzh-3A
    July 26, 2016 - Tumor thickness greater than 4.0 mm was associated with increased melanoma mortality compared with thinner … Although NMSC represents more than 97% of skin cancers,1 melanoma skin cancer is the pri- mary public … cancer screening is to detect skin can- cers, particularly melanoma, earlier in their clinical course than … melanoma in situ.30 These data suggest po- tential increased detection of clinically insignificant cancers rather … Cases with thin melanoma lesions (≤0.75 mm) had 38% higher odds of clinical skin exam than controls.
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RPB3rmcS9CK_eXPdzXSxZg
    July 01, 2010 - with previous fractures reported mean baseline BMD T-scores less than �3.0 (22–25). … Important methodological limitations of studies include nonrepresentative samples, cross-sectional rather … Instruments with fewer risk factors often did as well or better than those with more. … vs. greater than �2.0). … ‡ Some abstracts and articles were considered for more than 1 KQ.
  18. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary6/osteoporosis-screening-2011
    July 06, 2010 - previous fractures reported mean baseline BMD T-scores less than -3.0 22-25 . … Important methodological limitations of studies include nonrepresentative samples, cross-sectional rather … Instruments with fewer risk factors often did as well or better than those with more. … -2.5 25 ; and 3 trials enrolled women with T-scores greater than -1.0 85 , 86 , 91 . … 65; and b) men older than 50?"
  19. JAMA (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/pACFPdCoN8fVoddBs-_CLE
    November 12, 2019 - recommendation applies to women, the net ben- efit estimates are driven by biological sex (ie, male/female) ratherthan gender identity. … more studies of newer imaging tech- niques (breast MRI), surgical procedures (salpingo-oophorectomy ratherthan oophorectomy alone), and medications (aromatase in- hibitors). … Cancers associated with BRCA1 and BRCA2 mutations other than breast and ovarian.
  20. www.uspreventiveservicestaskforce.org/uspstf/document/behavioral-counseling-and-pharmacotherapy-interventions-for-/tobacco-use-in-adults-and-pregnant-women-counseling-and-interventions-september-2015
    September 21, 2015 - cessation advice by a physician, for example, were 76% more likely to have quit at 6 months or more than … The included reviews represented more than 800 RCTs, many of which were published since the last … We probably mitigated this potential shortcoming by basing our estimates on primary reviews ratherthan reporting results from several reviews. … The evidence base for varenicline, although consistent, is smaller than that for NRT and bupropion

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