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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/2kM7LY6ccceVo8bmdUXhYm
    September 01, 2002 - radiography, some cause severe pain, leading to 150,000 hospital admissions per year in persons older than … 65, 161,000 physician office visits, and more than 5 million days of restricted activity in those 45 … Older women have a much higher fracture rate than younger women with the same bone density because of … Overall, evidence is stronger for women older than 65 than for younger women because more research has … These specifications are not meant to be rigid rules but rather are intended to be general guidelines
  2. www.uspreventiveservicestaskforce.org/uspstf/recommendation/prostate-cancer-screening-2012
    May 15, 2012 - The USPSTF recognizes that clinical decisions involve more considerations than evidence alone. … However, neither screening nor treatment trials show benefit in men older than 70 years. … trial provides information about the incidence of metastatic disease only at the time of diagnosis, rather … For example, decreasing the PSA cutoff to 2.5 μg/L would more than double the number of U.S. men aged … The magnitude of effect was considerably greater in these 2 centers than in other countries ( Figure
  3. www.uspreventiveservicestaskforce.org/uspstf/recommendation/iron-deficiency-anemia-pregnant-women-young-children-screening-supplementation-1996
    January 01, 1996 - especially useful for infant testing, results obtained from capillary blood specimens are less reliable than … fortification of formula and cereal on healthy, nonanemic infants have focused primarily on laboratory ratherthan clinical outcomes. … effect, however by 8 months of age, 92% of study infants and 85% of controls were drinking cow's milk ratherthan study formula.
  4. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
    January 10, 2017 - periconceptional period, variation in benefits by risk factors, and supplementation benefits other thanRather than using a daily 400-μg dosage to define adequate intake, another approach is to set the threshold … 6 wk and no later than 24 mo after the expected date of delivery 39 Agopian et al, 5 … 6 weeks and no later than 24 mo after the expected date of delivery delivery 39 Werler et al, … h Compared with malformations other than NTDs or "other major malformations."
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/ghbfx9e3A6jQEqVW26y8Jv
    March 09, 2021 - Participants were more likely to benefit than the US screening-eligible population (eg, based on life … the NLST, 91% were White, less than 5% were Black, and less than 2% were Hispanic or Latino. … studies that apply risk prediction models to cohorts or representative samples of the US population ratherthan simulated populations. … Third, for accuracy, some included studies did not report accuracy metrics; rather, when sufficient data
  6. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/cervical-cancer-screening
    August 21, 2018 - is readily transmitted through sexual contact 1 , 2 and is recognized as a causative agent in more than … Cohort studies including fewer than 10,000 women were excluded, unless they addressed a subpopulation … Results were based on a “number of women screened” denominator, rather than intention-to-treat calculations … 35 years than for women older than 35 years (range, 0.2% 23 to 0.5% 13 , 19 , 21 , 22 ). … g Range, less than 0.1 to 7.7 years. Return to Table of Contents Table 2.
  7. www.uspreventiveservicestaskforce.org/home/getfilebytoken/T6Tquunynv3tWM65BFash2
    October 01, 2015 - The USPSTF recognizes that clinical decisions in- volve more considerations than evidence alone. … Using 2 types of NRT has been found to be more effective than using a single type. … However, it has been suggested that NRT may be safer than smoking during pregnancy (4, 11). … cessation (1, 9), most of the research on inter- ventions for smoking cessation focuses on cessation (ratherthan health outcomes) as a primary outcome.
  8. www.uspreventiveservicestaskforce.org/uspstf/recommendation/screening-depression-suicide-risk-adults
    June 20, 2023 - The USPSTF recognizes that clinical decisions involve more considerations than evidence alone. … The USPSTF recognizes that clinical decisions involve more considerations than evidence alone. … The USPSTF recognizes that race, ethnicity, and gender are all social rather than biological constructs … Adequate evidence that harms of pharmacotherapy are likely no greater than moderate. … No instrument was addressed in more than 1 study.
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/L5UwXoftg4JHw4buVDhjUT
    October 01, 2010 - The positive predictive value of screening is less than 10% in asymptomatic persons, including higher-risk … carci- noma, and less than 2% is adenocarcinoma (7–9). … The target population was asymptomatic persons older than 50 years. … for recurrent bladder cancer or in pa- tients with gross hematuria or lower urinary tract symp- toms, ratherthan in asymptomatic persons relevant for screening.
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary19/dental-caries-in-preschool-children-screening-2004
    April 15, 2004 - scope of opportunities for physician intervention for the prevention of dental diseases is much wider than … by the primary care clinician in identifying children who displayed 1 or more risk indicators other than … The pre-protocol level of appropriate management was estimated to have been no more than 25 percent. … , attention should be devoted to developing approaches to increase current levels of effectiveness, ratherthan simply documenting these levels.
  11. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review40/gonorrhea-screening-2005
    May 15, 2005 - Also, studies should be coordinated to define representative populations that can be studied over time ratherthan continuing to report from isolated cross-sectional convenience samples. … Research that examines population-level factors and association to STD transmission rather than focusing … The prevalence of gonorrhea will be lower than the prevalence of chlamydia in most settings. … Greater than 50% reported history of STD. 
  12. www.uspreventiveservicestaskforce.org/uspstf/recommendation/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
    August 20, 2019 - recommendation applies to women, the net benefit estimates are driven by biological sex (ie, male/female) ratherthan gender identity. … been more studies of newer imaging techniques (breast MRI), surgical procedures (salpingo-oophorectomy ratherthan oophorectomy alone), and medications (aromatase inhibitors). … Cancers associated with BRCA1 and BRCA2 mutations other than breast and ovarian.
  13. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/osteoporosis-screening-2002
    September 17, 2002 - 65 years of age, 161,000 physician office visits, and more than 5 million days of restricted activity … Older women have a much higher fracture rate than younger women with the same bone density because of … Overall, evidence is stronger for women older than 65 years of age than for younger women because more … Poor-fair: participants of trials may be different than primary care patients. … These specifications are not meant to be rigid rules but rather are intended to be general guidelines
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/bF_Y9vcT3eNPdHjTxPZsUZ
    April 17, 2023 - The USPSTF recognizes that clinical decisions involve more con- siderations than evidence alone. … The USPSTF recognizes that race, ethnicity, and gender are all social rather than biological constructs … ) • Adequate evidence that harms of pharmacotherapy are likely no greater than moderate. … ) • Adequate evidence that harms of pharmacotherapy are likely no greater than moderate. … No instrument was addressed in more than 1 study.
  15. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-familial-hypercholesterolemia/lipid-disorders-in-children-screening-july-2016
    August 09, 2016 - through elevated TC and LDL-C concentrations, which can be 2 to 3 times higher in children with FH than … Children with LDL-C concentrations greater than 155 mg/dL (to convert LDL-C values to mmol/L, multiply … by 0.0259) or TC concentrations greater than 260 mg/dL (to convert TC values to mmol/L, multiply by … , no such evidence was found. 18 When the aim of pharmacologic treatment is reducing disease risk ratherthan treating existing disease, only a low risk of harm is acceptable.
  16. untitled (pdf file)

    www.uspreventiveservicestaskforce.org/home/getfilebytoken/QWUmLEKdwcYA-AKGp5dNaQ
    August 09, 2016 - The USPSTF recognizes that clinical decisions involve more con- siderations than evidence alone. … and stroke in adulthood.1,2 With these studies, it may be possible to consider age- and sex-specific (ratherthan fixed) cutoff values to define thresholds for abnormal levels of TC and LDL-C.2 There is doubt … 155 mg/dL, a TC level greater than 260 mg/dL, or both, plus DNA evidence of a genetic mutation in a … Trial duration ranged from 6 weeks to 2 years, with most lasting less than 1 year.
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/TzddJozNQQZYmTohr64wMz
    June 07, 2016 - including those with previous syphilis infection, an infected sexual partner, HIV infection, or more than … sequence testing with an initial automated treponemal test yielded more false reactive test results than … studies of HIV-positive men20,23 concerned testing for syphi- lis as part of HIV disease monitoring ratherthan screening. … Reverse screening yielded a higher false-positive rate than traditional testing (0.6% vs 0%, P = .03)
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rm4E5SooP2GnqJ_HVRA5M4
    January 01, 2017 - Mean or median baseline AHI (or similar measure) was in the severe OSA range (AHI �30) for more than … a mean baseline ESS score less than 10,55,59,63,72,87,96,97,99,103,106 and 13 trials did not report … Rather, the focus was on the CPAP vs sham data. … guidelines was generally on diagnostic testing (of adults with symptoms suggestive of disor- dered sleep) ratherthan on screening (of asymptomatic people or those with unrecognized symptoms).
  19. www.uspreventiveservicestaskforce.org/home/getfilebytoken/vCzPVrVJfgFWfpWRdEHMKQ
    July 01, 2012 - The USPSTF recognizes that clinical decisions involve more considerations than evidence alone. … However, neither screening nor treatment trials show benefit in men older than 70 years. … A person choosing to be screened should believe that the possibility of benefit is more important than … trial provides information about the incidence of metastatic disease only at the time of diagnosis, rather … For example, decreasing the PSA cutoff to 2.5 �g/L would more than double the number of U.S. men aged
  20. www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening-1996
    January 01, 1996 - in Midwest and Mountain states, in large metropolitan areas (population 500,000 or greater) than in … smaller cities or rural areas, and in black and Hispanic young persons than in whites, Native Americans … A false-positive rate of less than 1 in 100,000 was reported in experienced, centralized laboratories … A stable indeterminate WB after 6 months can be assumed to be due to nonspecific antibody reaction ratherthan HIV infection. 33 , 48 Viral Culture and Polymerase Chain Reaction Assays Viral culture is

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