- 
                                        
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary19/dental-caries-in-preschool-children-screening-2004
April 15, 2004 - scope of opportunities for physician intervention for the prevention of dental diseases is much wider than … by the primary care clinician in identifying children who displayed 1 or more risk indicators other than … The pre-protocol level of appropriate management was estimated to have been no more than 25 percent. … , attention should be devoted to developing approaches to increase current levels of effectiveness, rather … than simply documenting these levels.
                                     
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review40/gonorrhea-screening-2005
May 15, 2005 - Also, studies should be coordinated to define representative populations that can be studied over time rather … than continuing to report from isolated cross-sectional convenience samples. … Research that examines population-level factors and association to STD transmission rather than focusing … The prevalence of gonorrhea will be lower than the prevalence of chlamydia in most settings. … Greater than 50% reported history of STD. 
                                     
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/osteoporosis-screening-2002
September 17, 2002 - 65 years of age, 161,000 physician office visits, and more than 5 million days of restricted activity … Older women have a much higher fracture rate than younger women with the same bone density because of … Overall, evidence is stronger for women older than 65 years of age than for younger women because more … Poor-fair: participants of trials may be different than primary care patients. … These specifications are not meant to be rigid rules but rather are intended to be general guidelines
                                     
                                                                    - 
                                        
www.uspreventiveservicestaskforce.org/home/getfilebytoken/bF_Y9vcT3eNPdHjTxPZsUZ
April 17, 2023 - The USPSTF recognizes that clinical decisions involve more con-
siderations than evidence alone. … The 
USPSTF recognizes that race, ethnicity, and gender are all social rather 
than biological constructs … ) 
• Adequate evidence that harms of 
pharmacotherapy are likely no greater 
than moderate. … ) 
• Adequate evidence that harms of 
pharmacotherapy are likely no greater than 
moderate. … No instrument was addressed in more than 1 study.
                                     
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/brca-related-cancer-risk-assessment-genetic-counseling-and-genetic-testing
August 20, 2019 - recommendation applies to women, the net benefit estimates are driven by biological sex (ie, male/female) rather … than gender identity. … been more studies of newer imaging techniques (breast MRI), surgical procedures (salpingo-oophorectomy rather … than oophorectomy alone), and medications (aromatase inhibitors). … Cancers associated with  BRCA1  and  BRCA2  mutations other than breast and ovarian.
                                     
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-screening-for-familial-hypercholesterolemia/lipid-disorders-in-children-screening-july-2016
August 09, 2016 - through elevated TC and LDL-C concentrations, which can be 2 to 3 times higher in children with FH than … Children with LDL-C concentrations greater than 155 mg/dL (to convert LDL-C values to mmol/L, multiply … by 0.0259) or TC concentrations greater than 260 mg/dL (to convert TC values to mmol/L, multiply by … , no such evidence was found. 18 
 When the aim of pharmacologic treatment is reducing disease risk rather … than treating existing disease, only a low risk of harm is acceptable.
                                     
                                                                    - 
                                        
www.uspreventiveservicestaskforce.org/home/getfilebytoken/QWUmLEKdwcYA-AKGp5dNaQ
August 09, 2016 - The USPSTF recognizes that clinical decisions involve more con-
siderations than evidence alone. … and stroke in adulthood.1,2 With
these studies, it may be possible to consider age- and sex-specific
(rather … than fixed) cutoff values to define thresholds for abnormal
levels of TC and LDL-C.2
There is doubt … 155 mg/dL, a TC level greater than 260 mg/dL, or both, plus DNA
evidence of a genetic mutation in a … Trial duration ranged from 6
weeks to 2 years, with most lasting less than 1 year.
                                     
                                                                    - 
                                        
www.uspreventiveservicestaskforce.org/home/getfilebytoken/vCzPVrVJfgFWfpWRdEHMKQ
July 01, 2012 - The USPSTF recognizes that clinical decisions involve
more considerations than evidence alone. … However, neither
screening nor treatment trials show benefit in men older
than 70 years. … A person choosing to be screened should believe that
the possibility of benefit is more important than … trial provides information
about the incidence of metastatic disease only at the time
of diagnosis, rather … For example, decreasing the PSA cutoff to 2.5 �g/L
would more than double the number of U.S. men aged
                                     
                                                                    - 
                                        
www.uspreventiveservicestaskforce.org/home/getfilebytoken/Rm4E5SooP2GnqJ_HVRA5M4
January 01, 2017 - Mean or median baseline
AHI (or similar measure) was in the severe OSA range (AHI �30)
for more than … a mean baseline ESS score less than 10,55,59,63,72,87,96,97,99,103,106
and 13 trials did not report … Rather, the focus was on the CPAP vs sham
data. … guidelines was generally on
diagnostic testing (of adults with symptoms suggestive of disor-
dered sleep) rather … than on screening (of asymptomatic people or
those with unrecognized symptoms).
                                     
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/human-immunodeficiency-virus-hiv-infection-screening-1996
January 01, 1996 - in Midwest and Mountain states, in large metropolitan areas (population 500,000 or greater) than in … smaller cities or rural areas, and in black and Hispanic young persons than in whites, Native Americans … A false-positive rate of less than 1 in 100,000 was reported in experienced, centralized laboratories … A stable indeterminate WB after 6 months can be assumed to be due to nonspecific antibody reaction rather … than HIV infection. 33 , 48 
 Viral Culture and Polymerase Chain Reaction Assays 
 Viral culture is
                                     
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www.uspreventiveservicestaskforce.org/uspstf/document/final-modeling-study18/colorectal-cancer-screening
May 18, 2021 - driver of differences in colorectal cancer incidence by race is access to screening and subsequent care, rather … than biological differences in natural history. … that there is strong evidence that Black adults have had lower rates of colorectal cancer screening than … Because the incidence of adenocarcinoma is increasing more slowly than that of carcinoid tumors of the … The appropriateness of more intensive colonoscopy screening than recommended in Medicare beneficiaries
                                     
                                                                    - 
                                        
www.uspreventiveservicestaskforce.org/home/getfilebytoken/_q6ZTL2Yg6f6rLp-Re9whD
June 24, 2025 - evidence, effective interventions generally address
multiple factors related to IPV (such as depression rather … magnitude of the overall harms of screening and interventions
for IPV can be bounded as no greater than … The USPSTF recognizes that clinical decisions involve more considerations than evidence alone. … an abusive relationship.1,24-26
Based on nationwide data from a recent study in older adults, more
than … physi-
cal violence, or stalking by an intimate partner in the past 12
months.3
IPV in Men | More than
                                     
                                                                    - 
                                        
www.uspreventiveservicestaskforce.org/uspstf/recommendation/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening
June 24, 2025 - harms of primary care interventions to prevent child maltreatment in children and adolescents younger than … The USPSTF recognizes that clinical decisions involve more considerations than evidence alone. … can result in significant injury, death, and long-term adverse health consequences. 1 , 5 , 6  More than … evidence, effective interventions generally address multiple factors related to IPV (such as depression rather … More than 44% of men report sexual violence, physical violence, or stalking by an intimate partner in
                                     
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/dvDjnZzW9PDxzKBauB4QxA
August 21, 2018 - changes caused primarily by high-risk types of human papillomavirus
(hrHPV), the causative agents in more than … ) is readily trans-
mitted through sexual contact1,2 and is recognized as a
causative agent in more than … Cohort studies including fewer than 10 000 women were
excluded, unless they addressed a subpopulation … Results were based on a “number of women
screened” denominator, rather than intention-to-treat calcula … 35 years (eTable 4 in the
Supplement) than for women older than 35 years (range, 0.2%23 to
0.5%13,19,21,22
                                     
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-latent-tuberculosis/latent-tuberculosis-infection-screening-september-2016
September 06, 2016 - Isoniazid is associated with higher rates of hepatotoxicity than placebo or rifampin. … Studies in which more than 25% of the study population were younger than 18 years or were known to be … alternative regimens against the standard isoniazid regimen to reduce harms, improve adherence, or both, rather … than to assess efficacy. … TB  IGRA test used in US studies higher than threshold used in non-US studies.
                                     
                                                                    - 
                                        
www.uspreventiveservicestaskforce.org/home/getfilebytoken/vTHBrY6VuqjoouJvUmtkr4
May 01, 2018 - (dis)utilities 
(k=7), and screening in subpopulations at higher risk (based on risk factors other than … For 
the strategies with a PSA threshold for biopsy less than 10.0 µg/L, incorporating information on … conceptual framework for determining how to screen men with an increased risk for 
prostate cancer rather … than actual guidance or recommendations for risk-stratified screening. … X    
-- Analytic Does not 
conceptualize 
natural history 
of cancer; 
rather, focuses 
on the effects
                                     
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www.uspreventiveservicestaskforce.org/uspstf/document/screening-for-hiv-in-pregnant-women-evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2013
November 15, 2012 - Mother-to-child transmission is responsible for more than 90% of pediatric HIV infections in the United … elective cesarean delivery before labor or rupture of membranes in women with HIV RNA levels greater than … Rather, this update focuses on new evidence on the effectiveness of combination antiretroviral regimens … In general, these studies reported lower transmission rates with antiretroviral therapy than expected … ‡ Some articles are included for more than 1 key question.
                                     
                                                                    - 
                                        
www.uspreventiveservicestaskforce.org/Home/GetFile/1/16813/prostate-cancer-models-overview/pdf
May 01, 2018 - (dis)utilities 
(k=7), and screening in subpopulations at higher risk (based on risk factors other than … For 
the strategies with a PSA threshold for biopsy less than 10.0 µg/L, incorporating information on … conceptual framework for determining how to screen men with an increased risk for 
prostate cancer rather … than actual guidance or recommendations for risk-stratified screening. … X    
-- Analytic Does not 
conceptualize 
natural history 
of cancer; 
rather, focuses 
on the effects
                                     
                                                                    - 
                                        
www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication
August 01, 2023 - adjusting for maternal age (aOR, 0.54 [95% CI, 0.29-0.95]). 8  Results adjusting for planned pregnancy rather … than maternal age were similar but not statistically significant (aOR, 0.57 [95% CI, 0.30-1.02]). 8 … of participants with prepregnancy diabetes or pregestational obesity for exposures measured as less than … of dose response in 3 of 4 studies; 19 , 20 , 22-24  1 study showed lower odds for daily use vs less than
                                     
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www.uspreventiveservicestaskforce.org/uspstf/document/-screening-evidence-summary/gestational-diabetes-mellitus-screening-january-2014
May 15, 2013 - Glycated hemoglobin level had poorer test characteristics than fasting plasma glucose level or the OGCT … present, whereas a negative LR less than 0.10 suggests a large and often conclusive probability that … If there were more than 3 studies and they were clinically homogeneous (that is, they included women … studies in this systematic review assessed the performance of screening tests compared with OGTT results rather … than pregnancy outcomes.