-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - Systematic reviews
have focused on the efficacy of specific drugs rather
than on the comparative effectiveness … bias in individual studies into the synthesis of evidence
by using individual risk of bias criteria rather … This
analysis provided pair-wise triangular comparisons for
drugs that were compared against placebo rather … than
network meta-analysis … More than half of the RCTs had medium risk of bias.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-screening_disposition-comments.pdf
April 01, 2012 - key questions 1, 4 and 5 to assess whether early
detection reduces the risk of developing outcomes
rather … These should be consistent and/or the
reasons for examining sensitivity and specificity rather
than … Peer Reviewer #2 Future
Research
Needs
This Reviewer finds the future research section rather
vague … “Losses in VF of
more than 5 dB [decibels] and gains of more than 3 dB
were associated with clinically … Rather, it states that evidence linking
screening with outcomes is lacking.
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis_hi_impact.pdf
January 01, 2014 - Rather, the reports will help to inform
and guide the planning and prioritization of research resources … have an uphill battle for approval,
although use of rilonacept when initiating allopurinol therapy (rather … These interventions are not proprietary products, but rather biologic
products prepared at the medical … mortality is due primarily to comorbid
renal failure, pulmonary fibrosis, or heart failure, rather … than the underlying autoimmune process itself.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
January 03, 2012 - definition of all cardiovascular events including
angina could lead to a different effect estimate than … validation data,
which may work for unmeasured confounders,9 it is
difficult to account for more than … reports given back to the General Practice,
that usually are less detailed), but better recording
than … Examples include
the degree of polynomial expressions, splines, or
additive rather than multiplicative … Overfit occurs when you are
fitting a model to random variations in the data
(i.e., noise) rather than
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
December 08, 2014 - indirectly reveals sites of metabolic bone turnover in reaction to bone
marrow metastatic disease rather … than the metastatic lesions directly. … one of the above)
• Multiple test (more than one of the above) vs. other multiple tests (more than … difference in accuracy may be due to reader experience rather than
the tests themselves. … Invited Peer
Reviewers may not have any financial conflict of interest greater than $10,000.
-
effectivehealthcare.ahrq.gov/sites/default/files/mcda_webinar_transcript2.pdf
August 27, 2012 - What we ended up doing
with our stakeholders is rather than going through each of
the seven criteria … August 27, 2012
21
rate the relative importance of the various topics on the
overall importance rather … than focusing specifically on
each of the criteria because, frankly, of feasibility
issues. … were
using that were consistent with the choices that we
observed so this is an indirect approach rather … obstructive pulmonary
disease, we didn’t say that some topics are not important
to us for study but rather
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_disposition-comments.pdf
April 01, 2012 - appropriate to consider early visual field deterioration as a
direct measure of visual impairment, rather … the drops, they
more likely agreed with the statement that glaucoma treatment
would “not do much” rather … at baseline, showing better preservation of visual field in
those patients who had initial surgery, rather … In the CIGTS study, the average loss of
visual field is less than ½ dB over seven years. … This does not involve the data itself, but, rather, how the data are
presented and executive summary
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
February 01, 2013 - comparative effectiveness studies and efficacy studies primarily addressed
stand-alone therapies rather … than combinations, common in current clinical practice. … than the combinations typically used in practice. … comparative effectiveness studies, and efficacy studies primarily addressed
stand-alone therapies rather … than the combinations typically used in practice.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
May 01, 2012 - The choice of whether to use summary variables to adjust for confounding rather than
traditional multivariate … Though the question “does rosuvastatin lead to more rhabdomyolysis than other statins?” … transparency may be reduced by inclusion of the
propensity score to a single term in an outcome model rather … propensity score to account for
situations where the outcome of interest might not be a disease at all, but rather … We
suggest clear descriptions and characterization of the study population using numbers (rather
than
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/biorepositories-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - If the repository is not created for a single investigator or patient registry but
rather as a resource … It should be noted that many participants will have more than one sample and often more than
one sample … Rather, they should
inform participants that, despite substantial efforts to safeguard their confidentiality … furthering medical research; an emphasis on intentionally asking patients to become research
participants, rather … be deposited in
biorepositories for future use (assuming appropriate patient consent is obtained), rather
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
February 01, 2014 - to the actual
metric used, which were primarily incidence rates (number of events per person-time) rather … estimate
(target of inference)
The NNT is the number of person-years of treatment with
aspirin, rather … The NNH is the number of person-years of treatment with
aspirin, rather than with placebo or comparators … still conclude that aspirin is likely to cause more harm than benefit. … We did not evaluate which preference assessment methods are most appropriate;
rather we used available
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
February 01, 2016 - Alcohol misuse is associated
with numerous health and social problems and more than 85,000
deaths per … It is estimated that fewer than 1 in 10
people who are treated for AUD receive medications.† Expanding … Alcohol is taken in larger amounts or over a longer period than intended.
2. … be interpreted to mean that medications cannot
be used to treat AUD in primary care settings, but rather
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
January 15, 2015 - versus the historically accepted gold standard of ICA will be presented for
context in the background rather … 5
Archived: This report is greater than 3 years old. … 6
Archived: This report is greater than 3 years old. … Coronary magnetic resonance angiography (MRA)
Utilizes magnetic fields and pulses or radio wave energy rather … than X-rays to view blood
vessels.
-
effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
January 01, 2012 - Rather, the reports will help to inform and guide the
planning and prioritization of research resources … Since that implementation,
more than 11,000 leads about topics have resulted in identification and … tracking of more than 900
topics across the 14 AHRQ priority areas and one cross-cutting area. … These interventions
are not proprietary products, but rather biologic products prepared at the medical … 23
As
such, PRP is thought by some to have potential to address the underlying pathology of OA rather
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
March 13, 2012 - has
been largely attributed to the fact that ovarian cancer typically presents at a much later stage than … ovary means that many cancers identified at
Stage I may represent a subgroup of less aggressive tumors rather … than a necessary first step in
the development of all tumors. … this project, we anticipate
that quantitative evidence synthesis will take the form of the model, rather … Invited Peer Reviewers may not have
any financial conflict of interest greater than $10,000.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-assessing-impact.pdf
September 01, 2018 - identifying the page numbers where the most relevant information on a quality
measure could be found rather … As the Southeast’s preeminent health care provider, Duke University Health System
attracted more than … 68,000 inpatient stays and more than 2 million outpatient visits in FY17. … own report be responsible for identifying the quality measures and
creating the hyperlinked tables rather … than having an outside entity linking across reports.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
March 01, 2016 - States, an estimated 26 million women between the ages of 15 and 50 have uterine
fibroids.1-4 More than … to randomized clinical comparisons of effectiveness, including medical
management versus surgical, rather … than restricting comparisons only to abdominal
hysterectomy. … pool a set of studies using random effects
depends not on how heterogeneous their outcomes are, but rather … Invited Peer
Reviewers may not have any financial conflict of interest greater than $10,000.
-
effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
March 01, 2010 - Food and Drug Administration for hypertension, so it obviously reduces blood pressure more than placebo … Food and Drug Administration for hypertension, it obviously reduces blood pressure more than placebo … The first question is, “Does aliskerin reduce blood pressure in hypertensive patients more than other … We also found out that the occurrence of infections would not be informative to stakeholders; rather, … would have on pulmonary function, so we decided not to limit the literature to prepubertal patients but rather
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
October 14, 2011 - use of
this test without a systematic review of current evidence has the potential to create harms rather … than benefits to health care outcomes. … studies will include only a single test (e.g., PCA3 or fPSA), and the comparison will be
made between, rather … than within, studies … In general, comparisons will be made between, rather than within, studies.
C.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
March 01, 2012 - than “AmGen.” … For
the sake of completeness, we chose to include all prior meta-
analyses, rather than trying to pick … We agree that adherence should be measured in the clinical
setting rather than in trials, and for that … Rather it is the HR associated with
the effect of prior fracture on subsequent fracture; the text was … The value of these interventions should
not automatically be assumed inconsequential, but rather
simply