-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
February 01, 2012 - Imperiale did report 95% CI for specificity
though he expressed specificity as the detection of normals rather … The 641
subjects primarily included patients who simply did not perform
the test rather than those … than a
reflection of the sensitivity of the assay. … The 641
subjects primarily included patients who simply did not perform
the test rather than those … than a
reflection of the sensitivity of the assay.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-236-mental-health-pregnancy-evidence-summary.pdf
April 01, 2021 - Pregnancy-associated suicide kills
more women than hemorrhage or preeclampsia. … exposure to lithium is more likely to be associated with overall
congenital and cardiac anomalies than … paucity of evidence does not mean that pharmacotherapy is not beneficial, nor
that harms do not exist; rather … trimester exposure
to lithium and overall congenital anomalies and cardiac anomalies may be greater than … As a result, our KQ 1 evidence base
controls for underlying severity as a confounder better than the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia-update_disposition-comments.pdf
April 25, 2013 - of tumors when ESAs are given at
the minimum required doses to reduce/avoid red cell transfusions (rather … manner that minimizes
ESA dose and exposure just enough to avoid or reduce red cell transfusions
rather … Page 95, line 37: Should probably cite the 3 individual studies, rather than relying
on citation of … The use of ESAs in these 3 trials was not to treat anemia, but rather to determine
if ESA therapy would … Rather than a prespecified endpoint for the majority of the ESA clinical trials, on-
study mortality
-
effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_media_wilkes.ppt
April 01, 2006 - and journals;
Public believes promotions about health and believes it is held to a higher standard than … Only to find that a clever RCT showed the procedure to be no better than a sham operation
HealthNet … already used to prevent bone loss after menopause
NCI used relative risk reductions in their promotion rather … than absolute risk reductions
At the press release and conference call no data was given to scientists … Arguably, understanding statistics is much more important for good citizenship than knowing algebra.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-transition-care_disposition-comments.pdf
May 27, 2014 - I suspect some of the variation
in results relates more to who was included in the study rather
than … than clinicians only. … For unsophisticated readers like me, you may want to
indicate why you chose an absolute rather than … We have re-run analyses using risk ratios rather
than risk difference and also described the
variability … than saying you found ‘no
difference’.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-dispositIon-comments-2022.pdf
January 01, 2022 - The authors mention in the discussion that RoB was
assessed by one person and then checked, rather than … classified as a measure of function due
to its focus even though it is more commonly
used for pain rather … than PTSD. … ’t
refer to psychotherapy interventions with
cognitive components (classified as
psychotherapy); rather … Figure 6:
how were studies that used more than 1 category handled?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
March 19, 2018 - Archived: This report is greater than 3 years old. … than a real increase). … SOE is
not graded per study rather per
outcome, for each unique
intervention/comparator pair. … This should be
indicated more clearly, and if CI, a comma rather
than “to” should be used (e.g., (0.46 … They will want to get to
work on writing the final document as quickly as
possible rather than going
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-231-dementia-interventions-evidence-summary_0.pdf
August 01, 2020 - people with Down syndrome, who are living longer and who overall experience higher
rates of dementia than … Because we excluded studies with fewer than 10 participants per study arm, we may
not have identified … these populations; therefore, we erred on the side of assessing a
body of research as insufficient rather … than ineffective.
-
effectivehealthcare.ahrq.gov/sites/default/files/nursing-home-safety_disposition-comments.pdf
May 27, 2016 - This is
especially the case as we reviewed
reviews rather than primary studies.
85. … The Technical Brief is not meant to
summarize findings of these studies but
rather to indicate where … The focus on
reviews of staffing intervention studies only rather than individual
studies gives an … The guiding questions are listed as if this is a
paper about an intervention, rather than a review of … Rather it listed the report's limitations.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
September 01, 2011 - Peer Reviewer 1 Methods
(Study
Section)
The pump was commonly used among women less than 24 weeks … positive
findings were likely due to the medium to high
risk of bias detected in observational studies
rather … than publication bias. … Overall, if you leave this section
in, I would simply call it pump malfunction, rather than failure. … For others we cannot say that patients were
probably not in labor, but rather that it is
unclear how
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
July 01, 2012 - They involve more than 600 health
care leaders and cover more than one-third of the U.S. … Rather, this framework
shows key pathways by which public reporting may lead to
harms, intermediate … Applicability was assessed,
rather than scored or rated, and may vary according to
the characteristics … what came before,
with an eye toward advancing understanding and a
focus on developing the science rather … than repeating
past approaches that have had a relatively low yield.
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-232-breathlessness-cancer-comments.pdf
November 19, 2020 - My
conclusion based on the evidence is that there the
evidence is inconclusive rather than opioids … of the
questions as most of the readers reviewing these
guidelines will be prescribing oncologists rather … I think this
should be the first table to summarize things based
on the endpoint rather than intervention … the discussion, I think it may be helpful to
reference the table I recommended based on
symptom (rather … than intervention).
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_disposition-comments.pdf
November 30, 2012 - The focus of this report was on how to change
provider behavior rather than on the preventive
interventions … Antibiotic timing adherence is an outcome with low
quality rather than insufficient evidence as an SSI … Questions
with Insufficient Data" (p. 134) so that it comes across as areas
for researchers to focus rather … than the end may be
more helpful. … The call for this is the paper is rather weak and muffled.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ear-infection_disposition-comments.pdf
May 04, 2013 - than an abnormal condition (i.e. an incidental
finding rather than a disease). … They represent a model for effectiveness rather that efficacy studies. … than
“uninterruptable.” … The key is to perhaps look at other issues rather than restudy the prsent
modalities
We agree that … Is a study of proton
pump inhibitors rather than of diet.
Thank you.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
May 29, 2025 - many comments that were outside of the scope of this project in that they addressed the CED process rather … This largely arises because the therapies recommended for CED are often devices or diagnostics, rather … than drugs or biologics, or are therapies being used for novel indications, without FDA-approval for … This largely arises because the therapies recommended for CED are often devices or diagnostics, rather … than drugs or biologics, or are therapies being used for novel indications, without FDA-approval for
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-future_research.pdf
May 01, 2012 - Primary sources of variability were identified as methodological rather than geographic. … Primary
sources of variability were identified as methodological rather than geographic, and included … Some needs address methodological
rather than intervention issues and did not squarely fit into a PICOTS … Intervention and Treatment considerations are not a direct focus of this research
need; rather, they … Therefore, rather than make strict assumptions
about the treatments being tested, we estimated the sample
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - Rather, we synthesized these studies
qualitatively, using the methods described below for
assessing … Rather, we searched for unpublished studies
through searches of clinical trials registries and regulatory … Rather, their purpose was
to evaluate test performance for lesion identification,
therefore providing … that it is not possible to perform a comprehensive contrast-
enhanced examination of the liver.22 Rather … Rather,
most studies of test performance that were not performed
specifically to evaluate or characterize
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
February 01, 2015 - However, we did not
collect examples of how existing systematic reviews have been used; rather we used … multiple relevant existing systematic reviews and
that they would typically use the “best” review rather … than include all existing reviews. … Rather, the synthesis from the prior review could be presented along with an updated qualitative
synthesis … than conducting a full
comprehensive search for existing reviews?
-
effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
March 15, 2016 - displayproduct&productid=2193
Published Online: March 15, 2016
Archived: This report is greater than … Comment Response
Peer Reviewer 1 General
Comments
My major concern is that the quality of studies is rather … transplant outcomes, given that
these have not changed appreciably in the last 10 to
15 years, but rather … many of
the questions that need to be addressed cannot be
answered through traditional RCTs, but rather … which foster an improvement in long term graft survival
and decrease the need for retransplantation, rather
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
July 01, 2012 - literature, most systematic reviews of medical
tests focus on “test accuracy” (or better, test performance) rather … than on the
impact of testing on patient outcomes. … in the literature, most
systematic reviews focus on “test accuracy” (or better, test performance) rather … than on the
impact of testing on patient outcomes.2,3 The links between testing, test results, and … Overall Suggestions
Many systematic reviews of medical tests focus on test performance rather than the