-
effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
January 03, 2012 - definition of all cardiovascular events including
angina could lead to a different effect estimate than … validation data,
which may work for unmeasured confounders,9 it is
difficult to account for more than … reports given back to the General Practice,
that usually are less detailed), but better recording
than … Examples include
the degree of polynomial expressions, splines, or
additive rather than multiplicative … Overfit occurs when you are
fitting a model to random variations in the data
(i.e., noise) rather than
-
effectivehealthcare.ahrq.gov/sites/default/files/worker-health_disposition-comments.pdf
May 31, 2016 - Archived: This report is greater than 3 years old. … Archived: This report is greater than 3 years old. … TEP Reviewer
#1
Methods Because the methods focused on integration rather than the
intervention, … evaluation might still contribute
relevant information if the comparator were OSH alone or HP
alone (rather … than no program at all).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
February 01, 2013 - risk for coronary artery disease (CAD) are less often referred for the appropriate diagnostic
test than … The
sensitivity of ECHO and SPECT was significantly higher than that of ECG. … Specificity of ECG was
less than that of CMR (borderline) and of ECHO. … evidence, it is also
possible that their prioritization represents their general research priorities, rather … than the state
of evidence for this specific topic.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
May 01, 2012 - The choice of whether to use summary variables to adjust for confounding rather than
traditional multivariate … Though the question “does rosuvastatin lead to more rhabdomyolysis than other statins?” … transparency may be reduced by inclusion of the
propensity score to a single term in an outcome model rather … propensity score to account for
situations where the outcome of interest might not be a disease at all, but rather … We
suggest clear descriptions and characterization of the study population using numbers (rather
than
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_disposition-comments.pdf
April 01, 2012 - appropriate to consider early visual field deterioration as a
direct measure of visual impairment, rather … the drops, they
more likely agreed with the statement that glaucoma treatment
would “not do much” rather … at baseline, showing better preservation of visual field in
those patients who had initial surgery, rather … In the CIGTS study, the average loss of
visual field is less than ½ dB over seven years. … This does not involve the data itself, but, rather, how the data are
presented and executive summary
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-adults-executive-130408.pdf
April 01, 2013 - Systematic reviews
have focused on the efficacy of specific drugs rather
than on the comparative effectiveness … bias in individual studies into the synthesis of evidence
by using individual risk of bias criteria rather … This
analysis provided pair-wise triangular comparisons for
drugs that were compared against placebo rather … than
network meta-analysis … More than half of the RCTs had medium risk of bias.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research.pdf
February 01, 2014 - to the actual
metric used, which were primarily incidence rates (number of events per person-time) rather … estimate
(target of inference)
The NNT is the number of person-years of treatment with
aspirin, rather … The NNH is the number of person-years of treatment with
aspirin, rather than with placebo or comparators … still conclude that aspirin is likely to cause more harm than benefit. … We did not evaluate which preference assessment methods are most appropriate;
rather we used available
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children_research-protocol.pdf
November 01, 2010 - Technical Expert Panel, to ensure comparative data from
contemporary treatment regimens, articles older than … Rather, the synthesis will
emphasize the specific patient characteristics, specific outcomes and status … For the comparator, if larger case series
were available, case reports and case
series with less than
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/lung-cancer-staging_research-protocol.pdf
December 08, 2014 - indirectly reveals sites of metabolic bone turnover in reaction to bone
marrow metastatic disease rather … than the metastatic lesions directly. … one of the above)
• Multiple test (more than one of the above) vs. other multiple tests (more than … difference in accuracy may be due to reader experience rather than
the tests themselves. … Invited Peer
Reviewers may not have any financial conflict of interest greater than $10,000.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
February 01, 2016 - Alcohol misuse is associated
with numerous health and social problems and more than 85,000
deaths per … It is estimated that fewer than 1 in 10
people who are treated for AUD receive medications.† Expanding … Alcohol is taken in larger amounts or over a longer period than intended.
2. … be interpreted to mean that medications cannot
be used to treat AUD in primary care settings, but rather
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2010_research-protocol.pdf
January 01, 2010 - They differ from classical hormones in that they are produced by a number of tissue or cell types rather … than by
specialized glands. … They generally act locally in a paracrine or autocrine rather than endocrine manner. … They should be taken daily, work over time rather than immediately, reduce or prevent inflammation and … serious AE (SAE); anaphylaxis]
i) Adverse events (AE): An injury caused by medical management–rather
-
effectivehealthcare.ahrq.gov/sites/default/files/01_-arthritis_potential_high_impact_june_2012.pdf
January 01, 2012 - Rather, the reports will help to inform and guide the
planning and prioritization of research resources … Since that implementation,
more than 11,000 leads about topics have resulted in identification and … tracking of more than 900
topics across the 14 AHRQ priority areas and one cross-cutting area. … These interventions
are not proprietary products, but rather biologic products prepared at the medical … 23
As
such, PRP is thought by some to have potential to address the underlying pathology of OA rather
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-assessing-impact.pdf
September 01, 2018 - identifying the page numbers where the most relevant information on a quality
measure could be found rather … As the Southeast’s preeminent health care provider, Duke University Health System
attracted more than … 68,000 inpatient stays and more than 2 million outpatient visits in FY17. … own report be responsible for identifying the quality measures and
creating the hyperlinked tables rather … than having an outside entity linking across reports.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
March 13, 2012 - has
been largely attributed to the fact that ovarian cancer typically presents at a much later stage than … ovary means that many cancers identified at
Stage I may represent a subgroup of less aggressive tumors rather … than a necessary first step in
the development of all tumors. … this project, we anticipate
that quantitative evidence synthesis will take the form of the model, rather … Invited Peer Reviewers may not have
any financial conflict of interest greater than $10,000.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_disposition-comments.pdf
March 01, 2012 - than “AmGen.” … For
the sake of completeness, we chose to include all prior meta-
analyses, rather than trying to pick … We agree that adherence should be measured in the clinical
setting rather than in trials, and for that … Rather it is the HR associated with
the effect of prior fracture on subsequent fracture; the text was … The value of these interventions should
not automatically be assumed inconsequential, but rather
simply
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-test_research-protocol.pdf
October 14, 2011 - use of
this test without a systematic review of current evidence has the potential to create harms rather … than benefits to health care outcomes. … studies will include only a single test (e.g., PCA3 or fPSA), and the comparison will be
made between, rather … than within, studies … In general, comparisons will be made between, rather than within, studies.
C.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
March 01, 2016 - States, an estimated 26 million women between the ages of 15 and 50 have uterine
fibroids.1-4 More than … to randomized clinical comparisons of effectiveness, including medical
management versus surgical, rather … than restricting comparisons only to abdominal
hysterectomy. … pool a set of studies using random effects
depends not on how heterogeneous their outcomes are, but rather … Invited Peer
Reviewers may not have any financial conflict of interest greater than $10,000.
-
effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
March 01, 2010 - Food and Drug Administration for hypertension, so it obviously reduces blood pressure more than placebo … Food and Drug Administration for hypertension, it obviously reduces blood pressure more than placebo … The first question is, “Does aliskerin reduce blood pressure in hypertensive patients more than other … We also found out that the occurrence of infections would not be informative to stakeholders; rather, … would have on pulmonary function, so we decided not to limit the literature to prepubertal patients but rather
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/outcomes-research-depression.pdf
October 01, 2021 - source(s), and other factors; as such, this toolkit describes general best practices and
considerations rather … than providing specific recommendations. … involving patients in the development of data
sharing policies and procedures in a more formalized manner than … Can a researcher use the data to address research questions other than those
originally submitted and … Researcher shall use appropriate safeguards to prevent use or disclosure of the Data
other than as provided
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
December 01, 2012 - ) developed DVT (overall, proximal, and distal) events in pharmacologic treatment group
were fewer than … up periods were defined
in most trials as the postoperative period and may
imply a more immediate rather … than longer term
follow up. … Followup periods were defined in most trials as the
postoperative period and may imply a more immediate rather … than longer term followup.