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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
    May 19, 2020 - For sparse data meta-analysis, we will employ the Peto Odds ratio method when event rates are less than … When event rates are between 5-10%, there are substantial differences between the N of two arms, or
  2. effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-disposition-comments.pdf
    March 31, 2025 - Committee Introduction While the review acknowledges the significant disparities in breastfeeding rates … unexpected infant death (SIUD) although our confidence is lower based on study design, low breastfeeding rates … lack of paid family leave, and workplace discrimination on breastfeeding initiation and duration rates … believes in the power of these grassroots organizations to support families and improve breastfeeding rates
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
    October 01, 2014 - A handful of studies reported low rates of serious direct harms (e.g., allergic reactions) associated … CT in HCC detection rates, subsequent imaging, or cost per HCC detected. … No study reported rates of adverse events associated with use of microbubble contrast agents in US, … and CT for HCC imaging, as suggested in recent guidance, such as those regarding minimum contrast rates … A meta-analysis of survival rates of untreated patients in randomized clinical trials of hepatocellular
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-evidence-summary.pdf
    April 01, 2018 - Physiologic Predictors of Severe Injury: Systematic Review, Evidence Summary Comparative Effectiveness Review Number 205 Physiologic Predictors of Severe Injury: Systematic Review Evidence Summary Background Unintentional injury is the fourth leading cause of death in the United States, the leading cause fo…
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
    August 01, 2007 - utilization characteristics among conventional and atypical APM users and then calculated mortality rates … Models of mortality rates within 0-40 days, 40-79 days, and 80-180 days of APM use were also constructed … Conventional APM users had lower rates of using antidepressants, but higher rates of using other psychotropic … Comparing the most frequently prescribed APMs individually with risperidone showed increased mortality rates
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
    August 01, 2012 - Three out of the four studies showed that rates of hospitalization were higher with generic use compared … outcomes: pharmacokinetics, the comparative dose of medication needed to control seizures, and switchback rates … controlled observational study reported data on gender, age, and polypharmacy impact on switchback rates … Three out of the four studies showed that rates of hospitalization were higher with generic use compared … controlled observational study reported data on gender, age, and polypharmacy impact on switchback rates
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
    August 01, 2012 - Three out of the four studies showed that rates of hospitalization were higher with generic use compared … outcomes: pharmacokinetics, the comparative dose of medication needed to control seizures, and switchback rates … controlled observational study reported data on gender, age, and polypharmacy impact on switchback rates … Three out of the four studies showed that rates of hospitalization were higher with generic use compared … controlled observational study reported data on gender, age, and polypharmacy impact on switchback rates
  8. effectivehealthcare.ahrq.gov/sites/default/files/renal-cancer_executive.pdf
    February 01, 2016 - In general, rates of harms were low among all treatment modalities, with minor (Clavien I-II) and major … However, rates of minor and major complications were similar among all three treatment modalities. … Thermal ablation had the lowest reported rates of acute kidney injury and non-urologic complications … Of note, we found that “overall survival rates and cancer-specific survival rates were excellent (95 … For instance, despite similar overall complication rates, partial nephrectomy had the highest rate of
  9. effectivehealthcare.ahrq.gov/sites/default/files/pdf/bundled-payments-quality-effects_research-protocol.pdf
    June 23, 2011 - o Utilization rates for specific services (e.g., readmission rate). … Source: www.effectivehealthcare.ahrq.gov Published Online: June 23, 2011 5 o Utilization rates … response: care redesign Study Outcomes – Change in: • Health care spending per episode • Utilization rates
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
    April 17, 2024 - Five-year survival rates range from 100% for men with local disease at diagnosis to 35.4% for men with … limited access to diagnostic tests and treatments for some populations.4,6,7 Prostate cancers vary in rates
  11. Dyspnea DEcIDE (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea_research.pdf
    April 01, 2010 - Dyspnea DEcIDE The DEcIDE (Developing Evidence to Inform Decisions about Effectiveness) network is part of AHRQ’s Effective Health Care Program. It is a collaborative network of research centers that support the rapid development of new scientific information and analytic tools. The DEcIDE network assists healt…
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
    February 25, 2014 - We are no longer looking at response rates. … Additional response and remission rates are summarized in ERROR Ref. … RR vs. rates alone) and as this information is not repeated in the narrative section, there is too much … paragraph on page 104 to find out that “there was no significant difference in the pooled remission ratesRates are found in the table 12 (page 107), but not the number of events, which I have to hunt down
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antibiotics-respiratory-infection_executive.pdf
    January 01, 2016 - antibiotic-resistant bacteria each year, causing approximately 23,000 deaths.1 Although reasons for higher rates … delaying prescribing found no difference in effect on overall antibiotic prescribing and similar rates … Baseline Prescribing Rates A key background factor may be baseline prescribing rates. … Baseline prescribing rates varied extremely widely across studies (from a low of <10% to ˃90%). … While it is likely true that baseline prescribing rates influence the impact of interventions to reduce
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol.pdf
    January 01, 2024 - Medical Therapies for Locally Advanced Gastric Adenocarcinoma Evidence-based Practice Center Systematic Review Protocol Project Title: Medical Therapies for Locally Advanced Gastric Adenocarcinoma I. Objectives for the Systematic Review Purpose of the Systematic Review The primary goal of this systema…
  15. effectivehealthcare.ahrq.gov/sites/default/files/decide16final-mortality-risk-in-copd-pts-using-theophylline.pdf
    December 01, 2009 - The rates of use were approximately 70% or higher over the first 18 months and then decreased in each … For COPD exacerbations, there were three regimens where exacerbation rates were significantly higher … was associated with an increased hospitalization rate for two regimens, with a trend towards higher rates … None were long enough to examine mortality or to compare exacerbation rates. … There is no reason to suspect there would be differential rates between groups based on treatment and
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-management_research.pdf
    December 01, 2009 - The rates of use were approximately 70% or higher over the first 18 months and then decreased in each … For COPD exacerbations, there were three regimens where exacerbation rates were significantly higher … was associated with an increased hospitalization rate for two regimens, with a trend towards higher rates … None were long enough to examine mortality or to compare exacerbation rates. … There is no reason to suspect there would be differential rates between groups based on treatment and
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
    March 01, 2012 - Switchback rates are surrogates for either efficacy or tolerability that some content experts felt … Rates for vomiting are reported and demonstrate non-significance between LTG and CBZ-CR. … This can result in significant differences in absorption rates between two generics. … another retrospective analysis of data from Ontario, Canada, Andermann et al.D3D evaluated switchback rates
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/anal-cancer-protocol.pdf
    September 26, 2023 - Treatment of Stage I-III Squamous Cell Anal Cancer Evidence-based Practice Center Systematic Review Protocol Project Title: Treatment of Stage I-III Squamous Cell Anal Cancer Publication Date: August 18, 2023 Amendment Date: September 26, 2023 (Amendments Details–see Section VI) I. Background Although anal ca…
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-evidence-heart-disease.pdf
    October 01, 2022 - PCI was associated with lower rates of subsequent target lesion revascularization at 1 year, but not … Finally, PCI was associated with higher rates of freedom from angina at 1 year (RR 0.65 [95% CI 0.50 … Eight SRs reported CV mortality rates (see Table 3). … (2019)27 and Khan et al. (2021)26 both reported reduced CV mortality rates associated with CTO- PCI … Qian et al. (2022)28 did not report CV mortality rates.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_executive.pdf
    June 01, 2013 - initially (like jejunoileal bypass) having been abandoned because of unacceptable complication rates … In the two RCTs comparing SG with RYGB, complications were minor, and rates were similar between groups … Followup times and rates were variable, and many studies did not state exactly when adverse events … As such, the rates of adverse events may be biased and lower than actual. … (The difference between complication rates seen in the major clinical trials of carotid endarterectomy

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