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effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
December 17, 2013 - Patient-centered benefits of disease-modifying treatments compared with
baseline
□ Reduction in relapse rate … Comparisons and
Outcomes
The overall strength of evidence for select outcomes for KQ1 (relapse rate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
February 01, 2018 - combine observed absolute effect size in individual arms across
studies, thereby producing a pooled rate
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_overview.pdf
March 27, 2014 - In children with JIA, does the rate and type of adverse eventsf differ
between the various DMARDs or
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
July 01, 2011 - Layout 1
Backgrounda
Obstructive sleep apnea (OSA) is a
relatively common disorder in the United
States that affects people of all ages, but is
most prevalent among the middle-aged and
elderly. Affected individuals experience
repeated collapse and obstruction of the
upper airway during sleep, which results in
reduce…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - of the Body of Evidence
The overall strength of evidence for selected outcomes
for KQ1 (relapse rate … The survival rate for the placebo arm was consistent with
survival rates reported in MS natural history … Glatiramer
acetate26-28
3
N = 483
4–22
Only 1 reported
overall rate: 87.3%
Most common
AE: … injection site
reactions
NR Only 1 reported
overall rate: 4.9% in
long-term extension
No Majority
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
May 01, 2005 - o Do not use poor or incomplete reporting, industry funding, or disclosed conflict of
interest to rate … Some
have elected to rate outcomes from poorly reported studies as having high risk of bias. … Another example of a criterion requiring topic-specific evaluation is the
expected attrition rate. … Reviewers of topics that focus on short-term clinical
outcomes may expect a low rate of attrition. … Systems to rate
the strength of scientific evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - Evidence Report on the
Source: www.effectivehealthcare.ahrq.gov
Published Online: December 1, 2010
Evidence-based Practice Center Systematic Review Protocol
Project Title: Comparative Effectiveness of First-Generation
and Second-Generation Antipsychotics in the Adult
Population
I. Background a…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F-5.xlsx
January 01, 2022 - Table F-5. Can. Cohort Studies
Table F-5. Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure (Mean, Median) Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain Duration Measure
(Mean, Median) Pain Duration, Mon…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-table-F5.xlsx
January 01, 2022 - Table F-5. Can. Cohort Studies
Table F-5. Cannabis cohort studies
PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure (Mean, Median) Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain Duration Measure
(Mean, Median) Pain Duration, Mon…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
January 30, 2012 - to 10 percent in people age
80 or older.4 Management of AF involves three distinct areas, namely, rate … A
second comparative effectiveness review focusing on the treatment of AF through rate or rhythm
control … constitutes a significant economic burden, costing Medicare
approximately $8 billion annually.11
The rate … individual study by using the
assessment instruments detailed in AHRQ’s Methods Guide.25 Briefly, we will rate … ; appropriate statistical and analytical
methods and reporting; no reporting errors; a low dropout rate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - (INSUFFICIENT)
Biologic: Etanercept had a lower rate of
withdrawals because of adverse events than … (INSUFFICIENT)
Biologic: Etanercept had a lower rate of withdrawals
because of adverse events than
-
effectivehealthcare.ahrq.gov/sites/default/files/krishnan_ahrq-mcda-presentation.pdf
August 27, 2012 - PowerPoint Presentation
Use of Analytic Hierarchy Process to
elicit stakeholder preferences for
prioritizing research
August 27, 2012
Jerry A. Krishnan, MD, PhD (jakris@uic.edu)
Professor of Medicine and Public Health
Associate Vice President for Population Health Sciences
on behalf of the CONCERT …
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
December 01, 2017 - Effectiveness and Safety of Bronchial Thermoplasty in Management of Asthma: Evidence Summary
Comparative Effectiveness Review
Number 202
Effectiveness and Safety of Bronchial Thermoplasty in
Management of Asthma
Evidence Summary
Objectives and Rationale for Review
This report summarizes a systematic
review, “E…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
January 01, 2014 - However, collagen dressings did not significantly
affect the wound recurrence rate. … The
ulcer recurrence rate was higher in the compression arm
than in the CHIVA arm (38 vs. 9%; P<0.05 … SEPS vs. compression alone
(2 RCTs)
High SEPS with superficial vein surgery does not improve the rate … ligation with vein stripping and found that the
ligation group had a significantly higher healing rate … Surgical correction of
isolated superficial venous reflux reduces long-term recurrence
rate in chronic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive-2007.pdf
January 01, 2007 - Layout 1
This report is an update to a Comparative
Effectiveness Review on management
strategies for renal artery stenosis (RAS)
from October 2006. The systematic review
included all studies of patients with
atherosclerotic RAS (ARAS) that
compared two or more interventions. It
also reviewed recent prospective cohort…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
July 01, 2012 - given in AHRQ’s General Methods Guide,1 we propose using the
terms “low,” “medium,” and “high,” to rate … Systems to
rate the strength of scientific evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
March 01, 2012 - design that, for
example, fails to recruit adequate numbers of subjects or has a very high dropout rate … a gap in valid
measurement instruments for patient-centered outcomes, and stakeholders may highly rate … Figure 2 shows power attained
over a range of sample sizes for various control rate values over a mean … Power increases with sample size, with control rate, and with length of
followup. … minimum followup of 2.5 years, a patient recruitment period of 5 years, and a constant recruitment rate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-treatment_research-protocol.pdf
September 30, 2010 - Assessment of Methodological Quality of Individual Studies
We will rate the quality of studies according … Attributable risk will be calculated as the outcome events rate in patients exposed to different
clinical … in rates of outcomes events in the active and control groups:
92,99
1 / (control group event rate … - treatment group event rate). … - treatment group event rate)*1000
We will calculate diagnostic values of different tests to diagnose
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
March 13, 2012 - Stage I disease has a 5-
year survival rate of over 95 percent.2 Five-year survival rates for patients … tumor directly invades or is adherent to other organs or structures).3 The relative 5-year
survival rate … In this report, prognostic outcomes relate to disease prognosis, generally
measured by rate of disease … Predictive outcomes reflect the rate of response
to adjuvant chemotherapy.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0261_07-16-2010.pdf
January 01, 2010 - Effective Health Care
Topic Number: 0280
Document Completion Date: 3-23-11
1
Results of Topic Selection Process & Next Steps
Interventions to modify physicians’ and other providers’ adherence to asthma guidelines will go forward
for refinement as a systematic review. The scope of this topic,…