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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/multiple-sclerosis_research-protocol.pdf
    December 17, 2013 - Patient-centered benefits of disease-modifying treatments compared with baseline □ Reduction in relapse rate … Comparisons and Outcomes The overall strength of evidence for select outcomes for KQ1 (relapse rate
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
    February 01, 2018 - combine observed absolute effect size in individual arms across studies, thereby producing a pooled rate
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_overview.pdf
    March 27, 2014 - In children with JIA, does the rate and type of adverse eventsf differ between the various DMARDs or
  4. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
    July 01, 2011 - Layout 1 Backgrounda Obstructive sleep apnea (OSA) is a relatively common disorder in the United States that affects people of all ages, but is most prevalent among the middle-aged and elderly. Affected individuals experience repeated collapse and obstruction of the upper airway during sleep, which results in reduce…
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
    April 01, 2015 - of the Body of Evidence The overall strength of evidence for selected outcomes for KQ1 (relapse rate … The survival rate for the placebo arm was consistent with survival rates reported in MS natural history … Glatiramer acetate26-28 3 N = 483 4–22 Only 1 reported overall rate: 87.3% Most common AE: … injection site reactions NR Only 1 reported overall rate: 4.9% in long-term extension No Majority
  6. effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
    May 01, 2005 - o Do not use poor or incomplete reporting, industry funding, or disclosed conflict of interest to rate … Some have elected to rate outcomes from poorly reported studies as having high risk of bias. … Another example of a criterion requiring topic-specific evaluation is the expected attrition rate. … Reviewers of topics that focus on short-term clinical outcomes may expect a low rate of attrition. … Systems to rate the strength of scientific evidence.
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
    December 01, 2010 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: December 1, 2010 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of First-Generation and Second-Generation Antipsychotics in the Adult Population I. Background a…
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-update-surv-rep-1-app-F-5.xlsx
    January 01, 2022 - Table F-5. Can. Cohort Studies Table F-5. Cannabis cohort studies PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure (Mean, Median) Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, Mon…
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-3-table-F5.xlsx
    January 01, 2022 - Table F-5. Can. Cohort Studies Table F-5. Cannabis cohort studies PMID Author, Year Study Design Setting Pain Population Pain Condition Age Measure (Mean, Median) Age, Years Female % Race, White % Race, Black % Race, Hispanic/Latino % Race, Asian % Race, Other % Pain Duration Measure (Mean, Median) Pain Duration, Mon…
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-atrial-fibrillation_research-protocol.pdf
    January 30, 2012 - to 10 percent in people age 80 or older.4 Management of AF involves three distinct areas, namely, rate … A second comparative effectiveness review focusing on the treatment of AF through rate or rhythm control … constitutes a significant economic burden, costing Medicare approximately $8 billion annually.11 The rate … individual study by using the assessment instruments detailed in AHRQ’s Methods Guide.25 Briefly, we will rate … ; appropriate statistical and analytical methods and reporting; no reporting errors; a low dropout rate
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
    March 01, 2013 - (INSUFFICIENT) Biologic: Etanercept had a lower rate of withdrawals because of adverse events than … (INSUFFICIENT) Biologic: Etanercept had a lower rate of withdrawals because of adverse events than
  12. effectivehealthcare.ahrq.gov/sites/default/files/krishnan_ahrq-mcda-presentation.pdf
    August 27, 2012 - PowerPoint Presentation Use of Analytic Hierarchy Process to elicit stakeholder preferences for prioritizing research August 27, 2012 Jerry A. Krishnan, MD, PhD (jakris@uic.edu) Professor of Medicine and Public Health Associate Vice President for Population Health Sciences on behalf of the CONCERT …
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
    December 01, 2017 - Effectiveness and Safety of Bronchial Thermoplasty in Management of Asthma: Evidence Summary Comparative Effectiveness Review Number 202 Effectiveness and Safety of Bronchial Thermoplasty in Management of Asthma Evidence Summary Objectives and Rationale for Review This report summarizes a systematic review, “E…
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
    January 01, 2014 - However, collagen dressings did not significantly affect the wound recurrence rate. … The ulcer recurrence rate was higher in the compression arm than in the CHIVA arm (38 vs. 9%; P<0.05 … SEPS vs. compression alone (2 RCTs) High SEPS with superficial vein surgery does not improve the rate … ligation with vein stripping and found that the ligation group had a significantly higher healing rate … Surgical correction of isolated superficial venous reflux reduces long-term recurrence rate in chronic
  15. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive-2007.pdf
    January 01, 2007 - Layout 1 This report is an update to a Comparative Effectiveness Review on management strategies for renal artery stenosis (RAS) from October 2006. The systematic review included all studies of patients with atherosclerotic RAS (ARAS) that compared two or more interventions. It also reviewed recent prospective cohort…
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
    July 01, 2012 - given in AHRQ’s General Methods Guide,1 we propose using the terms “low,” “medium,” and “high,” to rate … Systems to rate the strength of scientific evidence.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
    March 01, 2012 - design that, for example, fails to recruit adequate numbers of subjects or has a very high dropout rate … a gap in valid measurement instruments for patient-centered outcomes, and stakeholders may highly rate … Figure 2 shows power attained over a range of sample sizes for various control rate values over a mean … Power increases with sample size, with control rate, and with length of followup. … minimum followup of 2.5 years, a patient recruitment period of 5 years, and a constant recruitment rate
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/urinary-incontinence-treatment_research-protocol.pdf
    September 30, 2010 - Assessment of Methodological Quality of Individual Studies We will rate the quality of studies according … Attributable risk will be calculated as the outcome events rate in patients exposed to different clinical … in rates of outcomes events in the active and control groups: 92,99 1 / (control group event rate … - treatment group event rate). … - treatment group event rate)*1000 We will calculate diagnostic values of different tests to diagnose
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colon-cancer-gene-profiling_research-protocol.pdf
    March 13, 2012 - Stage I disease has a 5- year survival rate of over 95 percent.2 Five-year survival rates for patients … tumor directly invades or is adherent to other organs or structures).3 The relative 5-year survival rate … In this report, prognostic outcomes relate to disease prognosis, generally measured by rate of disease … Predictive outcomes reflect the rate of response to adjuvant chemotherapy.
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0261_07-16-2010.pdf
    January 01, 2010 - Effective Health Care Topic Number: 0280 Document Completion Date: 3-23-11 1 Results of Topic Selection Process & Next Steps  Interventions to modify physicians’ and other providers’ adherence to asthma guidelines will go forward for refinement as a systematic review. The scope of this topic,…

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