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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - (Low)
Certolizumab was equivalent to
golimumab and tocilzumab in
ACR20 response rate. … slightly as the age of
clinical trial patients increased; age did not
affect MTX efficacy or the rate … RCT AMPLE biologic DMARDs unclear 646 RA
patients
Abatacept +
MXT had
similar ACR20
response rate … as
adalimumab +
MTX
Significantly higher
drop-out rate due to
both adverse events
and serious … dropped slightly as the age of clinical trial patients
increased; age did not affect MTX efficacy or the rate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
March 01, 2013 - (Low)
Certolizumab was equivalent to
golimumab and tocilzumab in
ACR20 response rate. … slightly as the age of
clinical trial patients increased; age did not
affect MTX efficacy or the rate … RCT AMPLE biologic DMARDs unclear 646 RA
patients
Abatacept +
MXT had
similar ACR20
response rate … as
adalimumab +
MTX
Significantly higher
drop-out rate due to
both adverse events
and serious … dropped slightly as the age of clinical trial patients
increased; age did not affect MTX efficacy or the rate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - intrahepatic bile duct cancer in
the United States is about 1 in 132, with
an age-adjusted incidence rate … For CT, some evidence indicated
higher sensitivity for studies that used a contrast rate of
≥3 ml/s … than those with a contrast rate <3 ml/s, and higher
sensitivity for studies that used delayed phase … evidence on
administration of contrast for radiological procedures in
general also suggests a low rate … The overall rate of adverse drug-related events
was 10%, with all events classified as mild.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
January 01, 2010 - BMS than DES over the 30-month
follow up period (3.7/100 patients vs. 2.5/100 patients), while the rate … An additional concern is the higher rate of late
revascularization in DES compared to BMS, which tends … Unexpectedly, although a slightly higher unadjusted rate of anemia-
associated deaths was observed in … Despite these disparate intents and the size and complexity of
these two databases, our linkage rate … While the linkage rate of 76% is incomplete, it is reflective of populations known
to be absent from
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-executive-summary.pdf
March 01, 2024 - Executive Summary: ADHD Diagnosis and Treatment in Children and Adolescents
Comparative Effectiveness Review
Number 267
ADHD Diagnosis and Treatment in
Children and Adolescents
Executive Summary
Main Points
Diagnosis
• Multiple approaches showed promising diagnostic performance (e.g., usin…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0075_03-10-2009.pdf
January 01, 2009 - What treatments or therapies, alone or in conjunction with one another, provide the
highest rate of
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-cardio-dental.pdf
July 01, 2023 - 29% overall and 62% for older adults.9 The number of
people lacking dental insurance is triple the rate … Intraoral bleeding was higher in the group
who received dental treatment (7% rate). … Table of included studies
Author, Year
Country
Outcome Design Rate of Outcome
in Dental Care … The
bleeding rate was
significantly (p =
0.001) higher in the
dental treatment
group. … The bleeding
rate was significantly
(p = 0.001) lower in
the group that had
extraction prior to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
November 01, 2012 - A successful mode of care meets the need for assistance,
moderates the rate of functional decline, and … We did not rate strength of evidence for KQ 1a. … in physical
function
• Three studies provided low-strength evidence (high risk of bias) that the rate … Changes in mental
health
• Three studies provided low-strength evidence (high risk of bias) that the rate … We must also
acknowledge the potential for right censoring, whereby
the higher mortality rate in NHs
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - of a larger effect with greater exposure (dose, duration, adherence) either across or within studies
Rate … For each comparison of interest, rate the strength of evidence for:
Each major benefit (e.g., positive … mentioned, for each comparison of interest, reviewers in the Evidence-based Practice Centers (EPCs) should rate … step assumes that at least two reviewers with appropriate clinical and methodological expertise will rate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - risk of nausea High Meta-analysis of 15 studies indicates that venlafaxine has a higher
and vomiting rate … Comparative risk of somnolence Moderate Results from six trials indicate that trazodone has a higher rate … Duloxetine and venlafaxine have a
higher rate of discontinuations because of adverse events than SSRIs … Venlafaxine has a lower rate of discontinuations because of
lack of efficacy than SSRIs as a class.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
January 31, 2023 - Does this mean that the increased IBTR rate with IORT was small enough that it
“disappeared” when those … General Minor Points:
P.28, 3.2.2 – the authors cite that the ELIOT trial authors report a high rate … tens
of subgroup
analyses (such
as the ones
mentioned in the
comment) that
are not feasible
to rate … are tens of
estimates for
other outcomes
or from subgroup
analyses that are
not feasible to
rate … documented and not necessarily something that is widespread (but does of
course reimburse at a higher rate
-
effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
January 01, 2013 - a larger effect with greater exposure (dose, duration, adherence) either across or within studies
Rate … Strength of Evidence Grades (II)
For each comparison of interest, rate the strength of evidence for … mentioned, for each comparison of interest, reviewers in the Evidence-based Practice Centers (EPCs) should rate … step assumes that at least two reviewers with appropriate clinical and methodological expertise will rate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
March 26, 2013 - more than 10,000 patients who had undergone
colorectal surgery reported that the 90-day readmission rate … was 23.3 percent and the surgical
site infection rate was 18.8 percent within 30 days according to … Even if the
outcome rate is 10 percent (i.e., quite high), the sample size needs to be >400 patients … We will rate each study as being of low, intermediate, or high risk of bias on the basis of
adherence … We will rate the consistency of the data as
no inconsistency, inconsistency present, or not applicable
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Evidence Report on the
Source: www.effectivehealthcare.ahrq.gov
Published Online: May 19, 2010
Evidence-based Practice Center Systematic Review Protocol
Project Title: Efficacy and Comparative Effectiveness of Off-Label Use of Atypical
Antipsychotics – Update
I. Background and Objectives for the Sys…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
July 01, 2010 - health-
related quality of life, decreased disability, reduced
time to return to work/activities, higher rate … health-related quality of life,
decreased disability, reduced time to return to
work/activities, higher rate … health-
related quality of life, decreased disability, reduced
time to return to work/activities, higher rate … health-related quality
of life, decreased disability, reduced time to return
to work/activities, higher rate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_clinician.pdf
July 01, 2016 - .
���
Procedures
The infertility rate among women who had embolization
may be greater than the rate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
June 06, 2011 - Trials: We will rate the internal validity of each trial based on: the methods used for
randomization … on optimal quality-rating
methods.
10, 11
Therefore, we will not use a formal scoring system to rate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-disposition-comments.pdf
January 01, 2020 - encounter studies that were adequately powered to test
for no differences, for which we could potentially rate … This has been clarified in the text and table; we now
rate SOE separately for some hormone receptor … At any rate, it seems that a review on
breastfeeding policies in developed countries
would not exclude
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
October 26, 2012 - Survey Tool Used To Rate Research Gaps
Appendix D. … Survey Tool Used To Rate Research Questions
Appendix E. … The response rate was 100 percent (n=9); all questions received votes (Appendix F). … Survey Tool Used to Rate Research Gaps
Appendix D. … Survey Tool Used to Rate Research Questions
Appendix E.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-executive-summ.pdf
January 01, 2022 - Executive Summary_Systematic Review_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the PTSD-Repository Evidence Base
Systematic Review
Pharmacologic and Nonpharmacologic Treatments
for Posttraumatic Stress Disorder: 2022 Update of
the PTSD-Repository Evidenc…