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  1. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - (Low) Certolizumab was equivalent to golimumab and tocilzumab in ACR20 response rate. … slightly as the age of clinical trial patients increased; age did not affect MTX efficacy or the rate … RCT AMPLE biologic DMARDs unclear 646 RA patients Abatacept + MXT had similar ACR20 response rate … as adalimumab + MTX Significantly higher drop-out rate due to both adverse events and serious … dropped slightly as the age of clinical trial patients increased; age did not affect MTX efficacy or the rate
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine_surveillance.pdf
    March 01, 2013 - (Low) Certolizumab was equivalent to golimumab and tocilzumab in ACR20 response rate. … slightly as the age of clinical trial patients increased; age did not affect MTX efficacy or the rate … RCT AMPLE biologic DMARDs unclear 646 RA patients Abatacept + MXT had similar ACR20 response rate … as adalimumab + MTX Significantly higher drop-out rate due to both adverse events and serious … dropped slightly as the age of clinical trial patients increased; age did not affect MTX efficacy or the rate
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
    October 01, 2014 - intrahepatic bile duct cancer in the United States is about 1 in 132, with an age-adjusted incidence rate … For CT, some evidence indicated higher sensitivity for studies that used a contrast rate of ≥3 ml/s … than those with a contrast rate <3 ml/s, and higher sensitivity for studies that used delayed phase … evidence on administration of contrast for radiological procedures in general also suggests a low rate … The overall rate of adverse drug-related events was 10%, with all events classified as mild.
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
    January 01, 2010 - BMS than DES over the 30-month follow up period (3.7/100 patients vs. 2.5/100 patients), while the rate … An additional concern is the higher rate of late revascularization in DES compared to BMS, which tends … Unexpectedly, although a slightly higher unadjusted rate of anemia- associated deaths was observed in … Despite these disparate intents and the size and complexity of these two databases, our linkage rate … While the linkage rate of 76% is incomplete, it is reflective of populations known to be absent from
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-executive-summary.pdf
    March 01, 2024 - Executive Summary: ADHD Diagnosis and Treatment in Children and Adolescents Comparative Effectiveness Review Number 267 ADHD Diagnosis and Treatment in Children and Adolescents Executive Summary Main Points Diagnosis • Multiple approaches showed promising diagnostic performance (e.g., usin…
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0075_03-10-2009.pdf
    January 01, 2009 - What treatments or therapies, alone or in conjunction with one another, provide the highest rate of
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/rapid-response-cardio-dental.pdf
    July 01, 2023 - 29% overall and 62% for older adults.9 The number of people lacking dental insurance is triple the rate … Intraoral bleeding was higher in the group who received dental treatment (7% rate). … Table of included studies Author, Year Country Outcome Design Rate of Outcome in Dental Care … The bleeding rate was significantly (p = 0.001) higher in the dental treatment group. … The bleeding rate was significantly (p = 0.001) lower in the group that had extraction prior to
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/long-term-care-adults_executive.pdf
    November 01, 2012 - A successful mode of care meets the need for assistance, moderates the rate of functional decline, and … We did not rate strength of evidence for KQ 1a. … in physical function • Three studies provided low-strength evidence (high risk of bias) that the rate … Changes in mental health • Three studies provided low-strength evidence (high risk of bias) that the rate … We must also acknowledge the potential for right censoring, whereby the higher mortality rate in NHs
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
    January 01, 2010 - of a larger effect with greater exposure (dose, duration, adherence) either across or within studies Rate … For each comparison of interest, rate the strength of evidence for: Each major benefit (e.g., positive … mentioned, for each comparison of interest, reviewers in the Evidence-based Practice Centers (EPCs) should rate … step assumes that at least two reviewers with appropriate clinical and methodological expertise will rate
  10. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - risk of nausea High Meta-analysis of 15 studies indicates that venlafaxine has a higher and vomiting rate … Comparative risk of somnolence Moderate Results from six trials indicate that trazodone has a higher rate … Duloxetine and venlafaxine have a higher rate of discontinuations because of adverse events than SSRIs … Venlafaxine has a lower rate of discontinuations because of lack of efficacy than SSRIs as a class.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/partial-breast-irradiation-disposition-comments.pdf
    January 31, 2023 - Does this mean that the increased IBTR rate with IORT was small enough that it “disappeared” when those … General Minor Points: P.28, 3.2.2 – the authors cite that the ELIOT trial authors report a high rate … tens of subgroup analyses (such as the ones mentioned in the comment) that are not feasible to rate … are tens of estimates for other outcomes or from subgroup analyses that are not feasible to rate … documented and not necessarily something that is widespread (but does of course reimburse at a higher rate
  12. effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
    January 01, 2013 - a larger effect with greater exposure (dose, duration, adherence) either across or within studies Rate … Strength of Evidence Grades (II) For each comparison of interest, rate the strength of evidence for … mentioned, for each comparison of interest, reviewers in the Evidence-based Practice Centers (EPCs) should rate … step assumes that at least two reviewers with appropriate clinical and methodological expertise will rate
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
    March 26, 2013 - more than 10,000 patients who had undergone colorectal surgery reported that the 90-day readmission rate … was 23.3 percent and the surgical site infection rate was 18.8 percent within 30 days according to … Even if the outcome rate is 10 percent (i.e., quite high), the sample size needs to be >400 patients … We will rate each study as being of low, intermediate, or high risk of bias on the basis of adherence … We will rate the consistency of the data as no inconsistency, inconsistency present, or not applicable
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
    May 19, 2010 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: May 19, 2010 Evidence-based Practice Center Systematic Review Protocol Project Title: Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics – Update I. Background and Objectives for the Sys…
  15. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear_executive.pdf
    July 01, 2010 - health- related quality of life, decreased disability, reduced time to return to work/activities, higher rate … health-related quality of life, decreased disability, reduced time to return to work/activities, higher rate … health- related quality of life, decreased disability, reduced time to return to work/activities, higher rate … health-related quality of life, decreased disability, reduced time to return to work/activities, higher rate
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_clinician.pdf
    July 01, 2016 - . ��� Procedures The infertility rate among women who had embolization may be greater than the rate
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
    June 06, 2011 - Trials: We will rate the internal validity of each trial based on: the methods used for randomization … on optimal quality-rating methods. 10, 11 Therefore, we will not use a formal scoring system to rate
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-disposition-comments.pdf
    January 01, 2020 - encounter studies that were adequately powered to test for no differences, for which we could potentially rate … This has been clarified in the text and table; we now rate SOE separately for some hormone receptor … At any rate, it seems that a review on breastfeeding policies in developed countries would not exclude
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
    October 26, 2012 - Survey Tool Used To Rate Research Gaps Appendix D. … Survey Tool Used To Rate Research Questions Appendix E. … The response rate was 100 percent (n=9); all questions received votes (Appendix F). … Survey Tool Used to Rate Research Gaps Appendix D. … Survey Tool Used to Rate Research Questions Appendix E.
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-executive-summ.pdf
    January 01, 2022 - Executive Summary_Systematic Review_Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the PTSD-Repository Evidence Base Systematic Review Pharmacologic and Nonpharmacologic Treatments for Posttraumatic Stress Disorder: 2022 Update of the PTSD-Repository Evidenc…

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