- 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/scope-communicating-evolving-evidence-white-paper_0.pdf
June 01, 2025 - The SOE tables display results for different cannabis product categories 
8 
for pain response, pain … Living, Rapid Reviews in a 
Rapidly Evolving World. … compared with placebo in 
the short term (4 weeks to <6 months) 
Product, THC to CBD Ratio 
Pain Response
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/diabetic-neuropathy-disposition-170707.pdf
March 24, 2017 - One trial had no defined primary endpoint 
and no placebo response. … The other study was a very 
small crossover study with a small placebo response. … &productid=2436 
Published Online: March 24, 2017 
10 
Commentator 
& Affiliation Section Comment Response … &productid=2436 
Published Online: March 24, 2017 
11 
Commentator 
& Affiliation Section Comment Response … &productid=2436 
Published Online: March 24, 2017 
12 
Commentator 
& Affiliation Section Comment Response
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetic-neuropathy-disposition-170707.pdf
March 24, 2017 - One trial had no defined primary endpoint 
and no placebo response. … The other study was a very 
small crossover study with a small placebo response. … &productid=2436 
Published Online: March 24, 2017 
10 
Commentator 
& Affiliation Section Comment Response … &productid=2436 
Published Online: March 24, 2017 
11 
Commentator 
& Affiliation Section Comment Response … &productid=2436 
Published Online: March 24, 2017 
12 
Commentator 
& Affiliation Section Comment Response
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
September 01, 2013 - In response, many patients and families have sought to contribute to the research process, 
hoping either … The final section reviews emerging issues in the 
rapid evolution of patient-powered registries and research
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
October 01, 2014 - How is response to 
therapy done? … It 
is more accurate to talk of “metabolic response” or “anatomical / 
morphological response” instead … The wording has been changed to metabolic or anatomic 
response as appropriate. … Our systematic literature review was focused on treatment 
response. … I believe this 
review is intended to examine literature to follow response only.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_disposition-comments.pdf
June 12, 2012 - Given the rapid technical development in the field in 
the past decade, such older studies are not representative … We have reviewed the references and give a 
detailed response below. … Please refer to our response above. … Noted; see the following response to the 
literature. … It is unclear what “different response to exercise” means; 
b.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/patient-participant-generated-registries-guide-3rd-ed-addendum-white-paper.pdf
February 01, 2018 - While the sample from the 
PGR was subject to limitations and biases, the analysis provided rapid proof … participate in family life 
and the running of her household, the scale scored her as “zero”.30 In response … In response, the PGR PatientsLikeMe upgraded their data capture systems to collect information 
about … Although the data collected through PGRs can be rapid 
and a powerful means of exploring new hypotheses … The constant demand from participants in the PXE registry for more than a response of “I don’t 
know”
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/search-strategy-white-paper.pdf
February 01, 2025 - Since the first quarter 2023 search and review period there has been rapid development of 
generative … Tool review form  
 
Tool Name:  
Review Section Review Element  Reviewer Response 
TOOL 
CATEGORIZATION … Account Registration Yes | No 
Download Yes | No 
 
A-2 
Review Section Review Element  Reviewer Response … JSON 
EXPORT SECTION Export function Yes | No 
 
A-3 
Review Section Review Element  Reviewer Response … TRIP Rapid Reviews exclusion reason: not a search tool. 
 
 C-1 
Appendix C.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_disposition-comments.pdf
June 28, 2013 - &productID=1559 
Published Online: June 28, 2013 
 
Commentator & 
Affiliation 
Section Comment Response … productID=1559 
Published Online: June 28, 2013 
2 
 
Commentator & 
Affiliation 
Section Comment Response … productID=1559 
Published Online: June 28, 2013 
3 
 
Commentator & 
Affiliation 
Section Comment Response … productID=1559 
Published Online: June 28, 2013 
4 
 
Commentator & 
Affiliation 
Section Comment Response … at rest in patients with atrial fibrillation, unless 
there are ongoing symptoms felt to be due to rapid
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy-surveillance.pdf
September 01, 2017 - to OVID, the PubMed 
“similar articles” search works in advance of indexing, may be more useful for rapid … Column 3 contains expert response to “is this conclusion still supported?” … Expert Response 
AHRQ 
assessment 
(comment) 
Disulfiram (Table D-2, Appendix D. … Expert Response 
AHRQ 
assessment 
(comment) 
moderate). … Expert Response 
AHRQ 
assessment 
(comment) 
drinking (SOE: low).
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - There are currently two basic approaches for trying to determine whether a patient will have a 
poor response … is taking clopidogrel to see whether the platelets actually have become less prone to 
aggregate in response … These include rapid (point-of-care) 
platelet function assays (e.g., VerifyNow, PFA-100, Plateletworks … Clinical implications of clopidogrel non-
response in cardiovascular patients: a systematic review and … System of Oversight of Genetic Testing: A Response to the Charge of the Secretary of 
Health and Human
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bariatric-surgery_research.pdf
June 01, 2010 - It is a collaborative network of research centers that 
support the rapid development of new scientific … insulin regulation, increases immediately following bariatric surgery, 
which may explain the very rapid … Less 
clear is the mechanism for the rapid resolution of hyperlipidemia and hypertension, although this
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stem-cell-children_surveillance.pdf
October 29, 2012 - experts (one technical expert panel member and one peer 
reviewer of the original CER) provided their response … Assessment of the Need to 
Update Comparative Effectiveness 
Reviews: Report of an Initial Rapid 
Program … Both rapid and slowly progressive diseases 
High-strength evidence on number of subcutaneous 
nodules
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
October 05, 2015 - In this case, alternatives can include Emergency Response Teams (which 
encompass Behavioral Emergency … Response Teams,43 Rapid Response Teams,43 and 
Psychiatric Emergency Response Teams11) and pharmacologic … Psychiatric Emergency Response Teams 
o! … Response!Teams! 
•! Medication!protocols!that!employ!on6!or! 
off6label!use!of!FDA6approved! … Rapid response team for behavioral 
emergencies.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_surveillance.pdf
January 15, 2013 - Data suggested a 
sustained response for up to 22 
weeks duration, with 46 percent 
One small new long-term … However, response varied 
substantially within the treatment 
group, with 33 percent tolerating 
an increase … 2 or more 
patients were consistently 
associated with results of the 
START test for sapropterin 
response … Assessment of the Need to Update 
Comparative Effectiveness Reviews: Report 
of an Initial Rapid Program … Data suggested a sustained response 
for up to 22 weeks duration, with 46 percent 
achieving a 30-percent
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief1-care-coordination.pdf
April 01, 2021 - Rapid Evidence Product  
April 2021 
 
Care Coordination and Care Plans for 
Transitions Across Care … beneficiaries was common and was 
associated with over $17 billion in excess spending annually.17 In response
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief1-care-coordination.pdf
April 01, 2021 - Rapid Evidence Product  
April 2021 
 
Care Coordination and Care Plans for 
Transitions Across Care … beneficiaries was common and was 
associated with over $17 billion in excess spending annually.17 In response
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/outcome-definition-and-measurement-chapter-6.pptx
January 01, 2013 - be chronic (a long-term or permanent condition), acute (a condition with a clearly identifiable and rapid … questionnaires
May be more sensitive to symptoms experienced by a particular group of patients 
Item Response … Thus, they are thought to detect differences and changes in scores when they occur in response to interventions … Item Response Theory (IRT) and Computer Adaptive Testing (CAT)
IRT is a framework for developing tests … allows the selection of items from a questionnaire that are relevant solely to the respondent; each response
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
April 01, 2013 - Treatment Strategies
Medications
There has been rapid development and approval of 
vasodilator medications … Additional domains were used when appropriate: dose-
response association, impact of plausible residual … changes in median 
values in response to therapy. … Eight studies assessed mean 
or median change from baseline in response to therapy. … Long-term response to calcium 
channel blockers in idiopathic pulmonary arterial hypertension.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_disposition-comments.pdf
May 27, 2010 - www.effectivehealthcare.ahrq.gov  
Published Online: May 27, 2010  
2 
Comment 
Section 
Comment Response … www.effectivehealthcare.ahrq.gov  
Published Online: May 27, 2010  
3 
Comment 
Section 
Comment Response … Source: www.effectiveh   
Published Online: May 27, 2010  
4 
Comment 
Section 
Comment Response … www.effectivehealthcare.ahrq.gov  
Published Online: May 27, 2010  
5 
Comment 
Section 
Comment Response … We are concerned that private insurers may drop IMRT coverage in 
response to this draft report.