- 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-horizon-scan-high-impact-1506.pdf
June 01, 2015 - In T2DM, hyperglycemia is a result of insulin resistance or a diminished response to insulin. … Also, two pharmacokinetic-pharmacodynamic studies will be initiated to 
characterize dose response and … MannKind Corporation receives complete 
response letter from the FDA for Afrezza. 
[internet]. … acetonide intravitreal implant for treating 
chronic diabetic macular oedema after an 
inadequate response … acetonide 
intravitreal implant for treating chronic diabetic 
macular oedema after an inadequate response
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-disposition-comments.pdf
April 01, 2018 - Thank you. 
 
3 
 
Comment
ator & 
Affiliation 
Section Comment Response 
Peer 
Reviewer #1 … be clearer and to provide more 
detail. 
 
4 
 
Comment
ator & 
Affiliation 
Section Comment Response … TEP 
Reviewer #4 
Introduction Pg 27, line 19 I would include the risk of injury due to rapid transport … edited, p.  2 
 
5 
 
Comment
ator & 
Affiliation 
Section Comment Response 
Peer 
Reviewer #3 … Thank you. 
 
9 
 
Comment
ator & 
Affiliation 
Section Comment Response 
Peer 
Reviewer #2
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-executive-summary.pdf
December 01, 2022 - involvement: 
o For patients with diabetes: 
 Some improvement in medication adherence and treatment response … o Hepatitis C viral response and serious adverse events rates at “spoke” site with 
ECHO participation … The rapid increase in the use of telehealth in response to the COVID-19 pandemic is 
likely to produce
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_surveillance.pdf
August 30, 2014 - adj5 bipolar).tw. 384 
22 (rapid adj2 cycling adj5 bipolar).tw. 385 
23 (mixed adj2 state* adj3 bipolar … adj5 bipolar).tw. 431 
29 (rapid adj2 cycling adj5 bipolar).tw. 432 
30 (mixed adj2 state* adj3 bipolar … Haloperidol for psychosis-induced aggression or agitation 
(rapid tranquillisation). … The most commonly reported other outcome was 
response rate. … reported other outcome was response 
rate.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/products/high-risk-drugs/protocol
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
November 03, 2020 - (see discussion in Next Steps) 
Thank you, and please see the response 
immediately below. … preventable deaths and brain damage due to 
opioid overdose in post-surgical unitsxxxi as well 
as reduce rapid … Amid nationwide incentives to reduce 
opioid prescribing (currently at an 18-year low), 
rapid and non-consensual … Any discussion of 
opioid risks should also include the risks of rapid, 
inappropriate, forced tapering … Peer-reviewed studies increasingly show rapid 
and/or inappropriate nonconsensual opioid taper 
associated
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-adults_research-protocol.pdf
December 01, 2010 - rates with corresponding dose, duration of 
response, remission, relapse, speed of response time, time … 1st Generation 
and 2nd 
Generation 
Antipsychotics Intermediate outcomes 
 Core illness symptom-
response … rates 
with corresponding dose, duration 
of response, remission, relapse, 
speed of response, time … • Bipolar disorder, including manic or depressive phases, rapid cycling, and 
mixed states. … (rapid-cycling adj5 bipolar).tw. 
22. (rapid adj2 cycling adj5 bipolar).tw. 
23.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
January 01, 2010 - benefits of the vaccination may 
not be realized until there has been an appropriate 
immunological response … the individual, and 
the exposure definition should be created based 
on the expected timing of the response … In 
panel G, the depicted relationship shows a dose-
response in which the risk or benefit increases … Dosage and Dose-Response 
The concept of dose is an important consideration 
for the measurement of … Cumulative dose exposure definitions can be used 
to explore a dose-response relationship between 
the
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-health-mobile-apps-disposition-of-comments.pdf
May 20, 2022 - mental-health-apps/report 
Published Online: May 20, 2022 
2 
Summary of Peer Reviewer Comments and Author Response … Given the rapid 
advancements in technology and regulations around the use of such apps, we expect … products/mental-health-apps/report 
Published Online: May 20, 2022 
5 
Public Comments and Author Response … reports with sequential peer review and 
public comment 
 
Commentator 
& Affiliation 
Section Comment Response … We are concerned that the response to the following question - Is the app either 
being used or been
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol.pdf
September 13, 2024 - Misuse of Prescription Stimulants in Adults
Evidence-based Practice Center (EPC) Rapid Review Protocol … Food and Drug Administration (FDA) has commissioned a rapid review on the 
misuse of attention-deficit … This rapid review will focus on misuse of stimulants usually 
prescribed for ADHD. … Data Synthesis  
Due to the time and resource constraints of a Rapid Review, we will not conduct meta … periodical index"[pt])  
  
Filters: from 2020 - 2024  
 
 
 
 
	Evidence-based Practice Center (EPC) Rapid
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/cer-243-prehospital-airway-management-appendix-f-1_0.xlsx
January 01, 2016 - laryngeal mask airway	5671	ETI	Orotracheal intubation, video laryngoscopy, nasotracheal intubation, rapid … laryngeal mask airway	820	ETI	Orotracheal intubation, video laryngoscopy, nasotracheal intubation, rapid … laryngeal mask airway	306	ETI	Orotracheal intubation, video laryngoscopy, nasotracheal intubation, rapid … or laryngeal mask airway	4	ETI	Orotracheal intubation, video laryngoscopy, nasotracheal intubation, rapid … or laryngeal mask airway	8	ETI	Orotracheal intubation, video laryngoscopy, nasotracheal intubation, rapid
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/arthritis-psoriatric_surveillance.pdf
March 01, 2013 - A new meta-analysis9 found PsA 
Response Criteria (PsARC) 
response at 12-14 weeks was 
significantly … ACR20 response at 
12-16 weeks was greater for both 
anti-TNFs and other biologics. … Psoriasis area and severity 
index (PASI) response was greater 
the FDA in October, 
2012. … Assessment of the Need to Update 
Comparative Effectiveness Reviews: Report 
of an Initial Rapid Program … ACR50 
response rates were 
Did not conduct 
statistical tests on 
adverse events data.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/distributed-network-blueprint_research.pdf
June 01, 2010 - It is a collaborative network of research centers that 
support the rapid development of new scientific … Potential 
population-based electronic data sources for rapid 
pandemic influenza vaccine adverse event
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-review-masks-prevention-covid-version-2.pdf
December 01, 2021 - Rapid Evidence Product: Masks for Prevention of COVID-19 in Community and Healthcare Settings Version … 2
Rapid Evidence Product 
Version 2.0 (June 24, 2020) 
Masks for Prevention of COVID-19 in 
Community … This rapid review addresses the 
comparative effectiveness of various types of facemasks in the community … safety of mask re-use in practice is unknown.4,5 
Key Questions 
The Key Questions used to guide this rapid … Rapid Evidence Product.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_disposition-comments.pdf
June 05, 2013 - At least one study has demonstrated increased or rapid 
gastric emptying following gastric sleeve resection … No response needed. … No response needed. … Metabolic & 
Bariatric Surgery 
General It has been clearly demonstrated that RYGB and SG result in 
rapid … No response needed.
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
January 01, 2014 - productID=1734 
Published Online: November 4, 2013 
 
Commentator & 
Affiliation Section Comment Response … Peer Reviewer 6 Executive 
Summary 
ES-3 line 45 “rapid and potent” is used again; it was stated in … reversibly-binding reversible P2Y12 receptor antagonist that, 
when compared with clopidogrel, provides a more rapid … reversibly-binding reversible P2Y12 
receptor antagonist that, when compared with clopidogrel, 
provides a more rapid … While this response is relatively standard when the data analyzed 
are imperfect, there are pragmatic
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-of-vaccines.pdf
May 25, 2021 - No response needed. … No response needed. … No response needed. … For example, the Post-
Licensure Rapid Immunization Safety 
Monitoring (PRISM) program and 
Vaccine Safety … It may be 
possible that IIS data can be 
leveraged on a larger scale to support 
rapid, population-level
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-assessment-research-updates_research.pdf
September 15, 2008 - Reviews
Assessment of the Need to Update Comparative Effectiveness 
Reviews:  
Report of an Initial Rapid … In parallel with the 
methods effort, an initial, rapid program assessment was commissioned to assess … , 2008 
	Assessment of the Need to Update Comparative Effectiveness Reviews: Report of an Initial Rapid
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/lifecycle-assessment-disposition-comments.pdf
November 20, 2024 - tech-brief  
Published Online: November 20, 2024  
2 
Peer Reviewer and Public Comments and Author Response … Commentator 
and Affiliation 
Section Comment Response 
Peer reviewer #1 General This study conducted … tech-brief  
Published Online: November 20, 2024  
3 
Commentator 
and Affiliation 
Section Comment Response … tech-brief  
Published Online: November 20, 2024  
4 
Commentator 
and Affiliation 
Section Comment Response … tech-brief  
Published Online: November 20, 2024  
5 
Commentator 
and Affiliation 
Section Comment Response
                                     
                                                                    - 
                                        
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-disposition-comments-naloxone.pdf
November 27, 2017 - This strongly suggests that, while EMS 
response is optimal, it is not “critical.” … The urgency is 
further heightened by the rapid emergence of 
highly potent synthetic opioids, such as … State EMS 
Officials 
General 
Comments 
1Burns G, et al., Could chest wall rigidity be a 
factor in rapid … We did not make 
revisions in response to 
this comment. … to naloxone was 
defined, or did not define 
adequate response.”