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Total Results: 7,158 records

Showing results for "randomized controlled trial".

6041. Multiple-Sclerosis Executive (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
      April 01, 2015 - Literature Search Strategy We used bibliographic databases to identify publications on randomized controlled … Relevant bibliographic databases for this topic include MEDLINE®, the Cochrane Central Register of Controlled … Survival in MS: a randomized cohort study 21 years after the start of the pivotal IFN- 1b trial. … Informed shared decision making about immunotherapy for patients with multiple sclerosis (ISDIMS): a randomized … controlled trial.

6042. Layout 1 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
      May 01, 2010 - The FDA drug approval process mandates randomized clinical trials that demonstrate efficacy and safety … components, we made use of different categories of studies classified by study design and quality: • Randomized … controlled trials (RCTs) on the five selected indications of intracranial hemorrhage, massive bleeding … ff ic ie nt f or c om pa ri ng h ar m s an d be ne fi ts . 15 KQ=Key Question; RCT=randomized … controlled trial; OBS=comparative observational study; TE=thromboembolic; RBC=red blood cell; NA=not

6043. Psn-Pdf (pdf file)
      psnet.ahrq.gov/node/33804/psn-pdf
      March 03, 2016 - I had learned from that experience that just because there had been a randomized controlled trial involving … I now understand why randomized controlled trials are designed the way they are—because they're much

6044. In Conversation With… Paul McGann, MD | PSNet
      psnet.ahrq.gov/perspective/conversation-paul-mcgann-md
      July 10, 2024 - I had learned from that experience that just because there had been a randomized controlled trial involving … I now understand why randomized controlled trials are designed the way they are—because they're much,

6045. Screening for Gestational Diabetes: US Preventive Services Task Force Recommendation (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/WYvNt2GWJf8uGcAm3p_PFJ
      October 05, 2021 - If the patient’s glucose is not controlled af- ter these initial interventions, clinicians often prescribe … ); however, their specificity was low.29,34 Benefits of Early Detection and Treatment Screening No randomized … One trial found no association between treatment of ges- tational diabetes and impaired fasting glucose … AJ, Jeffries WS, Robinson JS; Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial … A randomised translational trial of lifestyle intervention using a 3-tier shared care approach on pregnancy

6046. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/osteoarthritis-knee-update-disposition.pdf
      May 04, 2017 - The review of the literature appears to be very comprehensive and appears to have captured all randomized … controlled clinical trials in to 2016. … TEP Reviewer #4 Discussion /Conclusio n Page 67 line 35-27: It appears that trial sample size … nerve stimulation on pain, pain sensitivity, and function in people with knee osteoarthritis: a randomized … controlled trial."

6047. Treatment of Osteoarthritis of the Knee: An Update Review (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-knee-update-disposition-archived.pdf
      May 04, 2017 - The review of the literature appears to be very comprehensive and appears to have captured all randomized … controlled clinical trials in to 2016. … TEP Reviewer #4 Discussion /Conclusio n Page 67 line 35-27: It appears that trial sample size … nerve stimulation on pain, pain sensitivity, and function in people with knee osteoarthritis: a randomized … controlled trial."

6048. Behavioral Counseling Interventions to Promote a Healthy Diet and Physical Activity for CVD Prevention in Adults Without Known CVD Risk Factors: USPSTF Recommendation Statement (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/HMSNGkJatRuN5VoVWfbuFL
      March 01, 2022 - Benefits of Counseling to Change Behavior and Outcomes The USPSTF included 113 randomized clinical trials … women.1,38 The mean age of participants ranged widely, from 18.5 to 79.5 years.1,38 The mean BMI of trial

6049. Final Topic Refinement Document - Role of Liquid Biopsy in Detection and Management of Cancer in the Medicare Population (pdf file)
      www.ahrq.gov/sites/default/files/wysiwyg/research/findings/ta/topicrefinement/liquid-biopsy-topicrefinement.pdf
      July 29, 2021 - We limited our search to randomized controlled trials (RCTs), observational studies, systematic reviews … MA = meta-analysis; RCT = randomized controlled trial; SR = systematic review Draft Population, … controlled trial • Longitudinal comparative observational studies 10 Definition of Terms in … controlled trial RNA Ribonucleic acid SR Systematic review Role of the Key Informants Key … -Non-randomized studies leading to bias: 17 For screening indications requiring a PMA approval

6050. The Empirical Evidence of Bias in Trials Measuring Treatment Differences | Effective Health Care (EHC) Program
      effectivehealthcare.ahrq.gov/products/treatment-effects-bias/research

6051. Using Interactive Health Information Technology to Support Women’s Choices for Birth After Cesarean - Final Report (pdf file)
      digital.ahrq.gov/sites/default/files/docs/publication/r21hs022114-shorten-final-report-2016.pdf
      January 01, 2016 - After (S2) p value 95% CI for Knowledge Increase 6.54 9.12 <0.01 1.76-3.40 As this was not a randomized … controlled trial, we cannot be confident that changes in scores were linked to the decision aid given … Future research is also needed to examine the robustness of decision aid effects in a larger randomized … Neonatal morbidity after elective repeat cesarean section and trial of labor. … Making Choices for Childbirth: A Randomized Controlled Trial of a Decision-aid for Informed Birth after

6052. Innovations In Behavioral Health Integration Transcript (doc file)
      integrationacademy.ahrq.gov/sites/default/files/2025-06/Innovations%20in%20Behavioral%20Health%20Integration_Transcript.docx
      January 01, 2025 - controlled trials, showing that this works for various conditions which I'll show in the next slide. … It was a multi-site cluster, randomized trial. … All of them were a matched pair of clinics in the same organization, and they were randomized to either … This was a 2 arm parallel superiority, pragmatic cluster, randomized trial, a mouthful for a really large … We had 43 randomized practices, in the end 22 control and 20 active practices, with one that withdrew

6053. Implementation, Adoption, and Scaling Workgroup: Key Factors and Considerations for Assessing the Value of Patient-Centered Clinical Decision Support (pdf file)
      digital.ahrq.gov/sites/default/files/IAS_Key%20Factors%20and%20Considerations%20for%20Assessing%20the%20Value%20of%20PC%20CDS.pdf
      October 01, 2024 - trial evaluating the use of CDS-based interventions on the management of care transitions among Medicaid … trial assessing the effect of a CDS intervention designed to reduce adverse events by alerting clinicians … These informants described efforts to conduct "mini RCTs [randomized controlled trials]" that require … Randomized trial of population-based clinical decision support to facilitate care transitions. … Information technology and medical missteps: evidence from a randomized trial.

6054. Implementation, Adoption, and Scaling Workgroup: Key Factors and Considerations for Assessing the Value of Patient-Centered Clinical Decision Support (pdf file)
      cdsic.ahrq.gov/sites/default/files/2024-10/IAS_Key%20Factors%20and%20Considerations%20for%20Assessing%20the%20Value%20of%20PC%20CDS.pdf
      January 01, 2024 - trial evaluating the use of CDS-based interventions on the management of care transitions among Medicaid … trial assessing the effect of a CDS intervention designed to reduce adverse events by alerting clinicians … These informants described efforts to conduct "mini RCTs [randomized controlled trials]" that require … Randomized trial of population-based clinical decision support to facilitate care transitions. … Information technology and medical missteps: evidence from a randomized trial.

6055. Final Progress Report: Effects of Extended Work Hours on ICU Patient Safety (pdf file)
      www.ahrq.gov/sites/default/files/2024-09/czeisler-report.pdf
      January 01, 2024 - We sought to conduct a randomized experiment to test the effect on patient safety of implementing shorter … Intern volunteers were randomized to work either the traditional schedule in the CCU and the intervention … Design of Intervention Trial After providing written informed consent, intern volunteers were randomized … differences in preventable adverse event rates, which should be investigated in a larger scale, multicenter trial … Subjects were observed in a controlled fashion performing equivalent tasks in a rested, sleep- deprived

6056. Chipra-89-Adhd-Behavior-Section-5-Attach-5 (pdf file)
      www.ahrq.gov/sites/default/files/wysiwyg/policymakers/chipra/factsheets/fullreports/chipra-89-adhd-behavior-section-5-attach-5.pdf
      February 02, 2012 - RCT indicates randomized controlled trial; Rec, recommendation. … Once daily atomox- etine treatment for children and adoles- cents with ADHD: a randomized, placebo- controlled … A randomized, double- blind, placebo-controlled study of guanfa- cine extended release in children and … , controlled trial with a community sample. … A 14-month randomized clinical trial of treatment strategies for attention-deficit/ hyperactivity disorder

6057. ADHD: Clinical Practice Guideline for the Diagnosis, Evaluation, and Treatment of ADHD in Children and Adolescents (pdf file)
      www.ahrq.gov/sites/default/files/wysiwyg/policymakers/chipra/factsheets/fullreports/chipra-88-measure-1-section-5-attachment-5.pdf
      February 02, 2012 - RCT indicates randomized controlled trial; Rec, recommendation. … Once daily atomox­ etine treatment for children and adoles­ cents with ADHD: a randomized, placebo- controlled … A randomized, double- blind, placebo-controlled study of guanfa­ cine extended release in children and … , controlled trial with a community sample. … A 14-month randomized clinical trial of treatment strategies for attention-deficit/ hyperactivity disorder

6058. AHRQ-Funded Patient Safety Highlights: Improving Healthcare Safety by Supporting Measure Implementation (pdf file)
      www.ahrq.gov/sites/default/files/wysiwyg/patient-safety/highlights/ps-project-highlights-measure-implementation.pdf
      August 01, 2025 - controlled trial … controlled trial with 450 patients across 3 0surgical clinics in Houston. … Despite these negative results, this study represents the first randomized trial of opioid use agreements … controlled field trial, and the sample was to consist of 400 employees from 8 companies who participate … Using a randomized controlled trial design, they applied the trigger to all patients cared for by study

6059. hemorrhage-postpartum-protocol-140611 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
      June 11, 2014 - After PPH has been controlled, followup management varies and may include laboratory testing (e.g., … not having value for PPH management Abbreviations: KQ=key question; ICU=Intensive Care Unit; RCT=randomized … controlled trial Source: www.effectivehealthcare.ahrq.gov Published online: June 11, 2014 … We will use the Cochrane Risk of Bias tool50 for randomized controlled trials and the Newcastle-Ottawa … trial.

6060. Disposition of Comments Report for Prevention of Healthcare-Associated Infections (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_disposition-comments.pdf
      November 30, 2012 - the other more useful. 16 Peer Reviewer #2 General Comments I find the discussion of cluster randomized … compliance with key components of the intervention if this is found to be unsatisfactory during the trial … The cluster randomized trials included in this report did use run in periods and could be considered … it is not clear why this method was singled out in the summation (as opposed to adaptive cluster randomized … “A Randomized Double-Blind Controlled Trial of Taurolidine-Citrate Catheter Locks for the Prevention