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Total Results: 7,158 records

Showing results for "randomized controlled trial".

5881. EvidenceNOW: New York City Cooperative | Agency for Healthcare Research and Quality
      www.ahrq.gov/evidencenow/projects/heart-health/about/cooperatives/nyc.html
      March 01, 2021 - The intervention is 12 months long and all sites were randomized into four intervention waves at the … Other Dissemination Activities Publication: Testing the Use of Practice Facilitation in a Cluster Randomized … Stepped Wedge Design Trial to Improve Adherence to Cardiovascular Disease Prevention Guidelines: HealthyHearts

5882. Disposition of Comments for Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non-Small-Cell Lung Cancer (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_disposition-comments.pdf
      June 12, 2013 - performed a thorough, deep search of the published literature, including NLM MEDLINE, EMBASE, Cochrane Controlled … alternatives for inoperable patients with stage 1 NSCLC the lack of comparative data between modalities in a randomized … It is not clear that there is equipoise present with such a trial. … Results of randomized studies looking at SBRT vs wedge or SBRT vs RFA are maturing and studies. … Randomized trials for PBRT vs IMRT are also not currently organized to my knowledge. 3.

5883. Final Progress Report: Making Acute Care More Patient Centered, Patient Safety Learning Laboratory (PSLL) (pdf file)
      www.ahrq.gov/sites/default/files/2024-07/bates3-report.pdf
      January 01, 2024 - In a randomized control trial involving over 10,000 patients, Fall TIPS reduced patient falls by 25% … trial. … The tool was implemented in a cluster-randomized, stepped-wedge trial on 12 units in neurology, oncology … Dykes, P.C., et al., Fall prevention in acute care hospitals: a randomized trial. … Dykes, P.C., et al., A randomized trial of standardized nursing patient assessment using wireless devices

5884. Effectiveness of Screening and Treatment of Subclinical Hypothyroidism or Hyperthyroidism (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_disposition-comments.pdf
      February 01, 2012 - It is a controlled clinical trial. … This study was described as a controlled trial not a randomized controlled trial.

5885. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
      March 28, 2019 - Consider adding “not-placebo-controlled” in parentheses. This was added. … Thus if the majority of sample came from a low risk of bias trial, the ROB domain in the SOE rating … Consider separate sections for placebo-controlled and no treatment trials. … phases” should be “was conducted in two randomized phases” This change has been made. … Peer reviewer #6 Discussion Could make more explicit that people that tolerate treatment were randomized

5886. Disposition of Comments Report for Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
      September 25, 2013 - This is reflected in the assessment of appropriate ROB items that were scored separately (e.g., randomized … clinical trial data is currently lacking. … There has been a call for a large randomized trial to evaluate the utility of platelet function testing … ES-22: In CURE, we did find an effect modification for GOF alleles. 4) Why no meta-analysis of randomized … Especially the need for a prospective randomized trial to assess whether alternative therapy based on

5887. Computerized Definitions Showed High Positive Predictive Values for Identifying Reasons for Hospitalizations in a Medicaid Population with Rheumatoid Arthritis (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-hospitalizations_research.pdf
      October 01, 2008 - with adverse events such as serious infections and congestive heart failure.3-6 Available clinical trial … Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled … trial.

5888. Interventions for High Body Mass Index in Children and Adolescents: US Preventive Services Task Force Recommendation Statement (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/kXAtzuxCxKJcHK9Fg63GA3
      April 01, 2023 - An important limitation of the pharmacotherapy studies was that there was only a single trial for each … Effectiveness of Behavioral Counseling and Pharmacotherapy Interventions Fifty randomized clinical trials … of the 8 trials were either conducted entirely in the US or had study sites in the US; the remaining trial … children aged 7 to 11 years.1,10 The evidence base for each medication was limited, consisting of only 1 trial … For example, in the largest trial of liraglutide, gastro- intestinal adverse effects occurred in 65%

5889. Recommendation: High Body Mass Index in Children and Adolescents: Interventions | United States Preventive Services Taskforce
      www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening
      June 18, 2024 - An important limitation of the pharmacotherapy studies was that there was only a single trial for each … Effectiveness of Behavioral Counseling and Pharmacotherapy Interventions Fifty randomized clinical … of the 8 trials were either conducted entirely in the US or had study sites in the US; the remaining trial … aged 7 to 11 years. 1 , 10 The evidence base for each medication was limited, consisting of only 1 trial … For example, in the largest trial of liraglutide, gastrointestinal adverse effects occurred in 65% of

5890. Physician Burnout | Agency for Healthcare Research and Quality
      www.ahrq.gov/prevention/clinician/ahrq-works/burnout/index.html
      November 01, 2023 - The AHRQ-funded Healthy Work Place Study (AHRQ grant HS18160), a cluster randomized trial of 166 physicians

5891. Diagnostic Stewardship Interventions To Reduce Diagnostic Error | Agency for Healthcare Research and Quality
      www.ahrq.gov/diagnostic-safety/resources/issue-briefs/dxsafety-dx-stewardship5.html
      August 01, 2024 - may be mediated by professional judgment rather than by a prespecified protocol or algorithm. 48,49 A randomized … trial in the Netherlands compared reflective testing with a control condition.

5892. Improving Quality In Cancer Screening: The Excellence Report For Colonoscopy - 2010 | Digital Healthcare Research
      digital.ahrq.gov/ahrq-funded-projects/improving-quality-cancer-screening-excellence-report-colonoscopy/annual-summary/2010
      January 01, 2010 - Using a clustered-randomized trial design, the project staff sent CORI-affiliated clinicians working

5893. In Conversation With… David Urbach, MD, MSc | PSNet
      psnet.ahrq.gov/perspective/conversation-david-urbach-md-msc
      June 12, 2019 - this double standard that we would not be satisfied that, for example, a drug worked unless we had a controlled … clinical trial: a good experimental study that endeavored to reduce selection biases and measurement … standard exists not just for drugs but also for other interventions in health care; we expect there to be randomized … Aviation didn't wait for a double-blind trial before barricading the cockpit doors or doing most of what

5894. EHR-based screening and intervention for intimate partner violence - Final Report (pdf file)
      digital.ahrq.gov/sites/default/files/docs/citation/r18hs025654-lenert_final-report-2023.pdf.pdf
      January 01, 2023 - We evaluated this intervention using a randomized stepped wedge study design deployed across the 15 … The trial was conducted in the setting of a control intervention of screening for IPV using nurse interviews … Clinics were assigned to 1 of 3 blocks and blocks were randomized in sequence. … tools for provider assessment and management of IPV risk using trained standardized patients in a controlled … The stepped wedge cluster randomised trial: rationale, design, analysis, and reporting.

5895. In Conversation With… David Juurlink, MD, PhD | PSNet
      psnet.ahrq.gov/perspective/conversation-david-juurlink-md-phd
      May 22, 2017 - Most randomized controlled trials on this issue that establish the efficacy of opioids are short term … There has never been a randomized trial to show that in the long term—at even a year, let alone 2 or … really debilitating chronic pain, is it conceivable that you might improve their quality of life with a trial … clinicians, this includes increased vigilance regarding the initiation or renewal of opioids and other controlled … PDMPs allow providers to review their patient's history with prescribed controlled substances prior to

5896. Opioid Overdose as a Patient Safety Problem | PSNet
      psnet.ahrq.gov/perspective/opioid-overdose-patient-safety-problem
      May 01, 2017 - clinicians, this includes increased vigilance regarding the initiation or renewal of opioids and other controlled … PDMPs allow providers to review their patient's history with prescribed controlled substances prior to … Most randomized controlled trials on this issue that establish the efficacy of opioids are short term … There has never been a randomized trial to show that in the long term—at even a year, let alone 2 or … really debilitating chronic pain, is it conceivable that you might improve their quality of life with a trial

5897. The Safety Challenges of Supervision and Night Coverage in Academic Residency | PSNet
      psnet.ahrq.gov/web-mm/safety-challenges-supervision-and-night-coverage-academic-residency
      February 21, 2024 - changes to therapeutics are rare, making it difficult to prove benefit.(2) Two recent single-center randomized … A randomized trial of nighttime physician staffing in an intensive care unit. … inpatient attending physician supervision on medical errors, patient safety, and resident education: a randomized … clinical trial.

5898. Disposition of Comments for CER 166 Calcineurin Inhibitors (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
      March 15, 2016 - In addition to RCTs, we also included non-randomized prospective and retrospective comparative trials … Introduction Page 3, Lines 23-24: the increased access to transplantation for individuals with well-controlled … Global Development Medical Affairs, Americas Results • Asserting improved patient outcomes based on randomized … controlled trials (RCTs) reporting only one or two year results and oftentimes lacking biopsy data … A comparative, randomized trial of concentration- controlled sirolimus combined with reduced-dose tacrolimus

5899. Screening for Overweight in Children and Adolescents: Where Is the Evidence? (pdf file)
      www.uspreventiveservicestaskforce.org/home/getfilebytoken/7K93Ldpe86aLuGS65CPKYp
      July 01, 2005 - Because most preventive interventions have not been tested in rigorous randomized trials, the USPSTF … No randomized trials of screening for childhood overweight or obesity in the clinical setting were found

5900. Recommendation: Healthy Diet and Physical Activity for Cardiovascular Disease Prevention in Adults Without Cardiovascular Disease Risk Factors: Behavioral Counseling Interventions | United States Preventive Services Taskforce
      www.uspreventiveservicestaskforce.org/uspstf/recommendation/healthy-lifestyle-and-physical-activity-for-cvd-prevention-adults-without-known-risk-factors-behavioral-counseling
      July 26, 2022 - Benefits of Counseling to Change Behavior and Outcomes The USPSTF included 113 randomized clinical … , 38 The mean age of participants ranged widely, from 18.5 to 79.5 years. 1 , 38 The mean BMI of trial