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Total Results: 7,158 records

Showing results for "randomized controlled trial".

5601. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
      February 01, 2018 - accounted for in analyses to the extent possible (known as informative censoring in the context of randomized … Additionally, while randomized clinical trials (RCTs) often limit their samples to a narrow and often

5602. Behavioral Counseling Research and Evidence-Based Practice Recommendations: U.S. Preventive Services Task Force Perspectives | United States Preventive Services Taskforce
      www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/behavioral-counseling-research-and-evidence-based-practice-recommendations-us-preventive-services-task-force-perspectives
      March 01, 2014 - physical activity and a healthful diet to prevent cardiovascular disease included studies in which trial … Studies with mixed populations were included if no more than 50% of trial participants had relevant diagnoses … A pragmatic-explanatory continuum indicator summary (PRECIS): a tool to help trial designers. … How pragmatic or explanatory is the randomized, controlled trial? … The application and enhancement of the PRECIS tool to the evaluation of a smoking cessation trial.

5603. Research Findings and Evidence Gaps in Youth Mental Health | Agency for Healthcare Research and Quality
      www.ahrq.gov/news/newsletters/e-newsletter/964.html
      July 01, 2025 - “For future research, there is a need for large, well-designed randomized controlled trials with long

5604. July 17 Webinar: Empower Patients Through Digital Healthcare Tools | Agency for Healthcare Research and Quality
      www.ahrq.gov/news/newsletters/e-newsletter/963.html
      June 01, 2025 - Practical design considerations for cluster randomized controlled trials: lessons learned in community

5605. Comparative Effectiveness and Safety of New Therapies (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-glucose-control_research.pdf
      July 01, 2010 - We have published an observational study regarding the effectiveness of exenatide;16 however, controlled … Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized … trial. … twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled

5606. HOPE-Genomics: Empowering Cancer Patients through Innovations in Information Technology-Based Precision Medicine - Final Report (pdf file)
      digital.ahrq.gov/sites/default/files/docs/citation/r21hs024984-gray-final-report-2019.pdf
      January 01, 2019 - First, the effectiveness of the HOPE-Genomics intervention in the context of cancer in a randomized … controlled trial. … The trial will compare usual care to those who receive their genomic test results with the HOPE-Genomics

5607. Methods Guide for Medical Test Reviews Chapter 10 (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-decision-models_methods.pdf
      July 01, 2012 - Such evidence could be obtained from well designed, conducted and analyzed randomized trials, or even … Randomized trials may exist suggesting that the treatment effects are similar in patients identified … of the diagnostic performance of PET to identify AD, but does not include longitudinal studies or randomized … Using the principles of randomized controlled trial design to guide test evaluation. … Optimization of CT colonography technique: prospective trial in 180 patients.

5608. PowerPoint Presentation
      www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa-2/090-decolonization-implementation.pptx
      April 01, 2025 - mupirocin antibiotic in the setting of chlorhexidine bathing to prevent infections in adult ICUs: a randomized … clinical trial. … Preventing surgical site infections: a randomized, open-label trial of nasal mupirocin ointment and nasal

5609. New Oral Anticoagulants | PSNet
      psnet.ahrq.gov/web-mm/new-oral-anticoagulants
      July 01, 2011 - The patient's pain was well controlled with the catheter, which was managed by the pain service at this … Data from large randomized trials comparing TSOACs to warfarin largely conclude that TSOACs are at least … treatment of acute venous thromboembolism: direct and adjusted indirect meta-analysis of randomised controlled

5610. Implementing a Patient Safety Program at a Large National Health System | PSNet
      psnet.ahrq.gov/perspective/implementing-patient-safety-program-large-national-health-system
      January 01, 2008 - Group AHS is currently participating with the Johns Hopkins Quality and Safety Research Group in a randomized … control trial funded by the Robert Wood Johnson Foundation. … Sometimes requiring absolutely randomized controlled trial evidence that a particular safety intervention … For example, we're not going to do a randomized trial of washing your hands. … trial.

5611. Medication Reconciliation: Whose Job Is It? | PSNet
      psnet.ahrq.gov/web-mm/medication-reconciliation-whose-job-it
      May 01, 2018 - medication reconciliation application and process redesign on potential adverse drug events: a cluster-randomized … trial. … Impact of an automated email notification system for results of tests pending at discharge: a cluster-randomized … controlled trial.

5612. Psn-Pdf (pdf file)
      psnet.ahrq.gov/node/49454/psn-pdf
      July 01, 2004 - example, by an APACHE II score greater than 25.(4) This approval is based on a large multicenter, randomized … , placebo- controlled trial (PROWESS) that showed that treatment with drotrecogin alfa (activated) was … .(5) At the same time, the follow-up study found little benefit in less sick patients, and another randomized … trial of patients with sepsis but low risk of death (ADDRESS) was recently stopped by the Data Safety

5613. Protocol - Continuous Positive Airway Pressure Treatment for Obstructive Sleep Apnea in Medicare Eligible Patients (pdf file)
      www.ahrq.gov/sites/default/files/wysiwyg/research/findings/ta/topicrefinement/sleep-apnea-protocol.pdf
      June 09, 2020 - As of 2008, the Centers for Medicare and Medicaid Services (CMS) covers an initial 12 week trial of … A large randomized trial of long-term CPAP use (SAVE) in people with coronary or cerebrovascular disease … more use of CPAP • Treatment (CPAP) compliance • Treatment (CPAP) discontinuation Design • Randomized … controlled trials (RCT) o Consider whether study met power calculation for the outcome(s) of interest … CPAP on Weight Change in Patients With Comorbid OSA and Cardiovascular Disease: Data From the SAVE Trial

5614. Improving Healthcare Using Engineering Principles | Agency for Healthcare Research and Quality
      www.ahrq.gov/funding/grantee-profiles/grtprofile-gurses.html
      November 01, 2023 - “AHRQ does not insist on randomized controlled trials.

5615. Final Progress Report: HIV/HCV Support Team to Improve Medication Safety and Engagement in Care (pdf file)
      www.ahrq.gov/sites/default/files/2024-02/berry-report.pdf
      January 01, 2024 - Methods: Phased, cluster-randomized trial with co-primary outcomes of 1) HIV medication errors and 2) … The project used a phased, cluster-randomized, roll-out, stepped-wedge study to assess whether the HST … toxicity, resistance, and viral rebound---validating the model by ensuring that results match observed trial … Results Overall, our team executed the interventional trial planned in Aim 1, which constituted the … We have accomplished some analyses of data from the trial, but, based on these results, we have altered

5616. Engaging Patients in Information Sharing and Data Collection: The Role of Patient-Powered Registries and Research Networks (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholders-engagement-others_white-paper.pdf
      September 01, 2013 - More importantly, the nature of the clinical trial may or may not yield information that patients and … world” practice and the effectiveness of treatments and procedures, and are to be distinguished from randomized … controlled trials or scientific experiments that cannot measure real-life experience, in some cases … In the view of some, only registries that are created, maintained, and controlled by patients or patient … Terms such as “patient-generated,” “patient-run,” “patient-powered,” and “participant-controlled” can

5617. www.ahrq.gov/sites/default/files/wysiwyg/hai/tools/mrsa/042-vap-prevention-slides.pptx
      October 01, 2024 - Case Example: Implementing the Intervention The team implements oral care protocol based on HAPPEN trial … physical and occupational therapy in mechanically ventilated, critically ill patients: a randomised controlled … trial. … Research: Oral care as prevention for nonventilator hospital-acquired pneumonia: a four-unit cluster randomized

5618. R18Hs017233-Fox-Final-Report-2011 (pdf file)
      digital.ahrq.gov/sites/default/files/docs/publication/r18hs017233-fox-final-report-2011.pdf
      January 01, 2011 - data items were obtained via chart review and practice records for baseline information (utilizing a randomized … DCCT Trial Research Group. (1993). … DCCT Trial Research Group. (2000). … "Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive

5619. Methods Guide for Medical Test Reviews - Editorial (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guide-editorial_methods.pdf
      July 01, 2012 - detailed handbook for authors of systematic reviews.5 This methods guide focuses primarily on reviews of randomized … controlled trials of interventions. … Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement

5620. Research Protocol: Breast Reconstruction After Mastectomy (pdf file)
      effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-reconstruction-mastectomy-protocol.pdf
      April 09, 2020 - chemotherapy Timing • Any Setting • Any, including single- and multicenter Design • Randomized … trial. … trial. … difference NRCS nonrandomized comparative study OR odds ratio PAP profundal artery perforator RCT randomized … controlled trial ROBINS-I Risk of Bias in Nonrandomized Studies of Interventions SIEA superficial