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www.ahrq.gov/sites/default/files/wysiwyg/ncepcr/webinars/behavioral-health-primary-care-webinar.pptx
March 07, 2024 - Coached mobile app platform for the treatment of depression and anxiety among primary care patients: A randomized … clinical trial, JAMA Psychiatry
15
Specific Research Aims
Aim 1: Adapt a DMHI, IntelliCare Plus, to … Aim 2: Develop and subsequently optimize a multicomponent implementation strategy
Aim 3: Conduct a randomized … rollout effectiveness-implementation trial of the IntelliCare Plus platform with optimization and a … regional delivery (care coordinators now work across regions)
24
Future Direction 1:
Adapting the Trial
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-d-surv-report-3-noninvasive-nonpharma_0.xlsx
January 01, 2022 - Poor
Garrido-Ardila 2021
[same trial as Garrido-Ardila 2020; subsequent publication]
[Surveillance … Veteran Affairs Rehabilitation Research and Development (Grant #RX000474)
Fair
Groessl 2020
[same trial … for Complementary and Integrative Health of the National Institutes of Health Fair
Joyce 2021
[same trial … Marshall 2021
[same trial as Saper 2017; subsequent publication]
[Surveillance Report 3] U.S. … Complementary and Integrative Health of the National Institutes of Health Fair
Roseen 2020
[same trial
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psnet.ahrq.gov/web-mm/steroids-and-safety-preventing-medication-adverse-events-during-transitions-care
September 09, 2013 - Antiemetic efficacy of dexamethasone—randomized, double-blind, crossover study with prochlorperazine … methylprednisolone on pain, fatigue, and appetite loss in patients with advanced cancer using opioids: a randomized … , placebo-controlled, double-blind trial. … 9, 2013
A reengineered hospital discharge program to decrease rehospitalization: a randomized … trial.
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www.ahrq.gov/ncepcr/tools/confid-report/physfeedback.html
February 01, 2016 - A recent systematic review of randomized clinical trials examining the effect of quality improvement … power of feedback reporting to influence professional behavior can be illustrated by the results of a randomized … , controlled trial evaluating the effect of electronic feedback reporting on the behavior of clinicians … Clinicians in a Danish county caring for similar types of diabetic patients were randomized to receive
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/nursing-staff-shortages-rapid-research-appendix-c.xlsx
January 01, 2024 - Clinical RNs 2010 to 2020 PubMed and CINAHL 34 US Descriptive (n=27)
Qualitative (n=1)
Non-randomized … Cluster-randomized, pre- and posttest, controlled trial using parallel-groups (n=1)
Quasiexperimental … Pre-posttest design( n=5)
Mixed methods preposttest design (n=2)
One group preposttest design (n=1)
Randomized-controlled … experimental study (n=1)
Mixed-method cluster randomized controlled trial with matched pairs randomization … Cochrane risk-of-bias tool for randomized trials – version 2 (RoB-2) tool for randomized studies and
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-staging_disposition-comments.pdf
November 20, 2014 - Peer Reviewer 4 Methods Table 12: what is a retrospective controlled trial? … controlled design. … Furthermore, we suggest mentioning the PETCAM trial, as this
randomized controlled trial seems to lack … Survival analysis of
PETCAM: a multicenter randomized controlled trial of PET/CT
versus no PET/CT for … The PETCAM trial has not been published
yet.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/trauma-interventions-maltreatment-child_research-protocol.pdf
January 12, 2012 - Study inclusion criteria
Category Criteria for inclusion
Study design Systematic reviews, randomized … controlled trials, nonrandomized controlled
trials, prospective and retrospective cohort studies, and … Controlled Trial"[Publication Type] OR "Randomized Controlled Trials as Topic"[Mesh] OR
"Single-Blind … Search #31 AND #42
#44 Search "Case-Control Studies"[Mesh]
#45 Search #31 AND #44
#46 Search "trial … Methods for identifying grey literature will include a review of trial registries,
specifically ClinicalTrials.gov
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psnet.ahrq.gov/sites/default/files/import/webmm.ahrq.gov.212_slideshow.ppt
February 01, 2010 - A randomized controlled trial.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-june-2016
June 15, 2016 - Adherence to colorectal cancer screening: a randomized clinical trial of competing strategies. … Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: a randomized … clinical trial. … The NordICC Study: rationale and design of a randomized trial on colonoscopy screening for colorectal … clinical trial.
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effectivehealthcare.ahrq.gov/sites/default/files/14_substanceabuse_potential_high_impact_june_2012.pdf
January 01, 2012 - A larger trial is planned. … in the ClinicalTrials.gov database, the
developers of the program state that they are conducting a randomized … , controlled trial that will
investigate the Text2Quit program combined with the Smokefree.gov program … July 2011 press release, the
manufacturer stated that data from a phase III placebo- and active-drug-controlled … Naltrexone (once-monthly controlled-release,
Medisorb). [138 p].
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-254-rural-telehealth-app-e.xlsx
January 01, 2021 - Risk of bias assessment: randomized controlled trials
Author, Year Randomization Adequate? … Groups Similar or Controlled for Important Baseline Differences?
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effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_disposition-comments.pdf
March 29, 2016 - Risk difference (RD) provides an absolute
measure for randomized controlled trial
data. … Trial. … Diagnostic performance and cost
of CT angiography versus stress ECG--a randomized
prospective study … Relations and
Advocacy
General Key References CCTA in the Symptomatic Stable Chest
Pain – Large Randomized … A
randomized, multicenter, multivendor study of myocardial
perfusion imaging with regadenoson CT perfusion
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www.ahrq.gov/hai/tools/ambulatory-care/cap-ed-setting-slides.html
January 01, 2018 - Level I evidence (high)—Evidence from well conducted, randomized controlled trials.
d.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/glaucoma-treatment_executive.pdf
April 01, 2012 - controlled trials and quasi-
randomized controlled trials of medical, laser, and
incisional surgical … and quasi-randomized controlled trials. … High-quality randomized
controlled trials have also shown that reduction of
intraocular pressure slows … The Ocular
Hypertension Treatment Study: a randomized trial determines
that topical ocular hypotensive … Early Manifest
Glaucoma Trial Group. Natural history of open-angle glaucoma.
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digital.ahrq.gov/ahrq-funded-projects/flualert-influenza-vaccine-alerts-providers-electronic-health-record/annual-summary/2011
January 01, 2011 - The FluAlert cluster cross-over trial began in October 2011 and will continue until March 2012. … mostly on track and the project budget funds are slightly underspent to conserve funds to complete the trial
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
September 28, 2021 - Benefits of Risk Assessment and Preventive Medication
The USPSTF considered 18 randomized clinical … RCTs (n = 15,767; 10 good-quality) to assess prevention of preeclampsia. 1 All trials were placebo-controlled … were included with trials of participants at increased risk (16 trials). 1 All trials were placebo-controlled … Follow-up data from the largest trial, the Collaborative Low-dose Aspirin Study in Pregnancy (CLASP), … CLASP: a randomised trial of low-dose aspirin for the prevention and treatment of pre-eclampsia among
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2022-update-app-g1.xlsx
January 01, 2022 - RoB judgement 2.1) Were ppts aware of their assigned intervention during the trial? … carers and people delivering the interventions aware of participants' assigned intervention during the trial … masking carers or ppts) were there deviations from the intended intervention that arose because of the trial … substantial impact (on the result) of the failure to analyse participants in the group to which they were randomized … RoB judgement 3.1) Were data for this outcome available for all, or nearly all, participants randomized
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/_2-KL_eHkuBhbGrzcAHsB-
June 01, 2022 - Thirteen randomized clinical trials (RCTs) (n = 2156) ad-
dressed the benefits of depression treatment … combination for adolescents with depression:
Treatment for Adolescents With Depression Study
(TADS) randomized … controlled trial. … SPARX, a computerised self help intervention for
adolescents seeking help for depression:
randomised controlled … non-inferiority trial.
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www.ahrq.gov/hai/tools/ambulatory-care/cap-pc-setting-slides.html
January 01, 2018 - Level I evidence (high)—Evidence from well conducted, randomized controlled trials.
d.
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psnet.ahrq.gov/issue/interruptions-and-multi-tasking-moving-research-agenda-new-directions
March 23, 2011 - March 29, 2023
Evidence and efficacy: time to think beyond the traditional randomised controlled … trial in patient safety studies.