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effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_research-protocol.pdf
November 03, 2014 - For studies of efficacy and effectiveness, we will
limit the inclusion to randomized controlled trials … If the situation arises where there are no
randomized controlled trials for an intervention of interest
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www.uspreventiveservicestaskforce.org/uspstf/document/draft-research-plan/autism-spectrum-disorder-young-children-1
February 25, 2021 - interventions include: the Early Start Denver Model (ESDM), applied behavioral analysis (ABA)/Discrete Trial … Study design
KQs 1, 3–5: Randomized clinical trials; nonrandomized and quasi-experimental designs;
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www.ahrq.gov/sites/default/files/wysiwyg/professionals/quality-patient-safety/patient-safety-resources/resources/advances-in-patient-safety/vol3/Furmaga.pdf
January 01, 2005 - Major
outcomes in high-risk hypertensive patients
randomized to angiotensin-converting enzyme
inhibitor … Principal
results of the Controlled Onset Verapamil
Investigation of Cardiovascular Endpoints
(CONVINCE … ) trial. … The
International Verapamil-Trandolapril Study
(INVEST): a randomized controlled trial. … Morbidity
and mortality in patients randomized to double-blind
treatment with a long-acting calcium-channel
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6jFgJYJSbMc48mj2uKsAhB
October 01, 2014 - Translating
the Diabetes Prevention Program lifestyle intervention for weight loss into pri-
mary care: a randomized … trial. … lifestyle modification on diet, weight, physical fitness, and blood pressure
control: 18-month results of a randomized … trial. … -
ity rates in treated hypertensive men with additional risk factors are high but can
be reduced: a randomized
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digital.ahrq.gov/sites/default/files/docs/citation/r21hs024977-dexheimer-final-report-2018.pdf
January 01, 2018 - with anti-epileptic medications.4 The other 30% are
intractable who are not adequately controlled … Patients will be randomized to the honest broker, EHR alert, or no intervention. … Electronic health record-based decision support to improve
asthma care: a cluster-randomized trial. … We will trial the two methods to see which is more effective. … Natural
Language Processing for Identifying Epilepsy Surgery Candidates: A Randomized, Controlled Pilot
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
December 01, 2012 - filters were not applied to any of the searches although the Cochrane Central
Register only contains randomized … or controlled clinical trials. … venous thrombosis; VTE: venous
thromboembolism; PE= pulmonary embolism; OR= pulmonary embolism; RCT=Randomized … Abbreviations: RCT=randomized controlled trial; pts=patients; yr(s)=years; NR=not reported; vs.= versus … CER=comparative effectiveness review; RCT=randomized controlled trial; pts=patients; yr(s)=years; NR=
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
September 28, 2021 - Benefits of Risk Assessment and Preventive Medication
The USPSTF considered 18 randomized clinical … RCTs (n = 15,767; 10 good-quality) to assess prevention of preeclampsia. 1 All trials were placebo-controlled … Fifteen smaller trials were conducted in various developed countries. 1 , 8 , 16-18
In general, trial … were included with trials of participants at increased risk (16 trials). 1 All trials were placebo-controlled … Follow-up data from the largest trial, the Collaborative Low-dose Aspirin Study in Pregnancy (CLASP),
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psnet.ahrq.gov/perspective/implementing-fall-prevention-program
November 29, 2023 - However, increasing numbers of randomized control trials (RCTs) and well-designed before-and-after trials … A randomised controlled trial. Age Ageing. 2007;36:507-513. [go to PubMed]
18. … A randomized trial of identification bracelets to prevent falls among patients in a rehabilitation hospital
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www.ahrq.gov/sites/default/files/wysiwyg/research/findings/ta/topicrefinement/afib_topicref.pdf
January 01, 2020 - infarction, exacerbation of heart failure, and cardiomyopathy if the ventricular rate is
insufficiently controlled … the least potential for bias (i.e.,
high quality systematic reviews with or
without meta-analysis), randomized … controlled trials, controlled observational
studies, registry studies
• Case series or uncontrolled … clinical outcomes in patients with chronic heart failure in the Carvedilol Or Metoprolol
European Trial … (COMET): randomised controlled trial.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
January 07, 2016 - As far as I can tell, though, even though it is by far the largest
randomized clinical trial (RCT) ever … the ACT trial,
which says, “The implications of this adequately powered, well-conducted clinical trial … The meta-analysis included 63 randomized controlled trials which were
mostly small and open label. … Circulation 2011, which was a well powered (n= 2308), multicenter, randomized,
placebo controlled trial … This brings into question the results
of at least 13 randomized, controlled trials that reported NAC
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
April 01, 2012 - controlled trials, prospective
observational studies, health systems research, and dissemination of … controlled trials that were then underway and sought to identify potential studies and research … Because of the lengthy course of this disease, some randomized controlled trials
have been published … understandable from the
patient’s perspective but may greatly reduce the ability to draw conclusions from the trial … For example, while there may be randomized
controlled trials of screening, the question about the adverse
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effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
January 01, 2011 - Variables that are potentially on the
pathway from treatment to outcome are not
controlled for, as … data are
described in detail in a number of textbooks.12-13
For matched study designs (e.g., case-controlled … assess the balance in study covariates achieved by
matchingin a similar manner to the comparison of
randomized … treatment groups from a randomzed
clinical trial.
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www.ahrq.gov/sites/default/files/wysiwyg/evidencenow/cooperatives/evidencenow-executive-summary-nc.pdf
November 01, 2017 - Evaluation
The Cooperative is conducting a stepped-wedge, stratified,
cluster randomized trial, where … the practices are randomized
on geography (East vs.
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digital.ahrq.gov/sites/default/files/docs/publication/r03hs022559-corser-final-report-2015.pdf
January 01, 2015 - A series of covariate-controlled within group (i.e. same patients linked to their
ongoing PCP providers … Interactive preventive health record to enhance delivery of recommended care: a
randomized trial. … Electronic patient messages
to promote colorectal cancer screening: a randomized controlled trial. … Electronic alerts versus on-demand decision support to improve dyslipidemia
treatment: a cluster randomized … controlled trial.
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psnet.ahrq.gov/web-mm/failure-ensure-patient-safety-leads-patient-falls-nursing-homes
August 14, 2024 - In response, the PCP completed a second evaluation and recommended a trial of discontinuing oral quetiapine … Approach to Fall Prevention and Improving Resident Safety
Repeatedly, through individual randomized … controlled trials, systematic reviews, and clinical practice guidelines, it has been recommended that … care residents with mild to moderate cognitive impairment or dementia: subgroup analysis of a cluster randomized … controlled trial.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cad-women-diagnosis_executive.pdf
June 01, 2012 - criteria were met:
• Original data or related methodology paper of
an included article
• Randomized … controlled trial, prospective or
retrospective observational study, or registry
• Not a systematic … Randomized trials comparing functional versus
anatomic modalities. … Stress
echocardiography in the evaluation of women presenting with
chest pain syndrome: a randomized … Artery Disease: Results From
the What Is the Optimal Method for Ischemia Evaluation in
Women (WOMEN) Trial
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www.ahrq.gov/pqmp/implementation-qi/toolkit/antipsychotic/other-resources.html
September 01, 2021 - “ Several open and double-blind placebo-controlled studies show that typical and atypical antipsychotics … Generally, an adequate trial of psychotherapy precedes consideration of medication, and psychotherapy … Clinical Guidelines: Strong empirical evidence (non-randomized controlled trials, cohort or case-control … PPWG
A: Well controlled RCTs, large meta-analyses, or overwhelming clinical consensus.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/WN7F3WW6RQFDkHay87a3Dx
November 18, 2020 - Standardization of LDCT Screening and Follow-up
of Abnormal Findings
The randomized clinical trials ( … Reduced lung-cancer mortality with volume
CT screening in a randomized trial. … Screening by chest radiograph and
lung cancer mortality: the Prostate, Lung,
Colorectal, and Ovarian (PLCO) randomized … trial. … Systematic review and meta-analysis of
randomized and nonrandomized trials on safety
and efficacy of
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/smoking-pregnancy-infants_disposition-comments.pdf
February 25, 2014 - Of note, six of the 28 good and fair quality studies
included in the review randomized fewer than 50 … In addition, the priority
scores (100 to 500) for Trial I was 122 (5th percentile) and
Trial II it … However, this study was not placebo controlled and
although researchers may have been blind the participants … It would be good
to insert randomized after 20 to show that the sampling was
random. … It is surprising that
breastfeeding was not controlled for in the analyses or
addressed in the report
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psnet.ahrq.gov/node/848110/psn-pdf
April 26, 2023 - In response, the PCP completed a second evaluation and recommended a trial of discontinuing oral
quetiapine … Approach to Fall Prevention and Improving Resident Safety
Repeatedly, through individual randomized … controlled trials, systematic reviews, and clinical practice
guidelines, it has been recommended that … residents with mild to moderate cognitive impairment or dementia: subgroup analysis of a cluster
randomized … controlled trial.