-
psnet.ahrq.gov/issue/can-medical-students-identify-potentially-serious-acetaminophen-dosing-error-simulated
March 30, 2011 - Effect of a mobile app on prehospital medication errors during simulated pediatric resuscitation: a randomized … clinical trial.
-
psnet.ahrq.gov/issue/effectiveness-and-cost-transitional-care-program-heart-failure-prospective-study-concurrent
April 24, 2019 - Effects of an enhanced discharge planning intervention for hospitalized older adults: a randomized … trial.
-
psnet.ahrq.gov/issue/therapeutic-errors-involving-diabetes-medications-reported-united-states-poison-centers
September 27, 2023 - intervention on medication safety after hospitalization in persons prescribed high-risk medications: a randomized … clinical trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1306.pdf
June 01, 2013 - patients
with CF who have two copies of the CFTR-F508del mutation, according to recent phase II
trial … In a randomized controlled trial, patients with COPD (n=1,577 ) who were at increased
risk of exacerbations … In a
randomized, double-blind, placebo-controlled, phase III trial, cosponsored by the Cystic Fibrosis … patients with CF who have two copies of the CFTR-
F508del mutation, according to recent, phase II trial … : In a randomized controlled trial, patients with COPD who were at increased risk
of exacerbations
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-modeling-study/aspirin-to-prevent-cardiovascular-disease-preventive-medication
April 26, 2022 - Outcomes over a 10-year horizon are in the full report. 13
Analysis
Model simulations mimicked a randomized … in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled … trial. … aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled … trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-pain-opioid-treatment_research-protocol.pdf
December 19, 2013 - We will include
randomized controlled trials (RCTs), cohort studies, and case-control studies
for all … Literature Databases: Ovid MEDLINE, PsychINFO, CINAHL, Cochrane
Central Register of Controlled Trials … will be abstracted that is relevant
for assessing applicability will include the number of patients randomized … of Bias of Individual Studies
Predefined criteria will be used to assess the quality of individual controlled … Randomized trials will be evaluated with
appropriate criteria and methods developed by the Cochrane
-
psnet.ahrq.gov/issue/first-kids-medication-errors
February 03, 2021 - Health literacy-informed communication to reduce discharge medication errors in hospitalized children: a randomized … clinical trial.
-
psnet.ahrq.gov/node/49771/psn-pdf
July 01, 2016 - Understanding and preventing wrong-patient electronic
orders: a randomized controlled trial. … effects of a computerized physician order entry
nearly hard-stop alert to prevent a drug interaction: a randomized … controlled trial.
-
psnet.ahrq.gov/web-mm/novel-drug-misuse
September 30, 2010 - example, by an APACHE II score greater than 25.( 4 ) This approval is based on a large multicenter, randomized … , placebo-controlled trial (PROWESS) that showed that treatment with drotrecogin alfa (activated) was … ( 5 ) At the same time, the follow-up study found little benefit in less sick patients, and another randomized … trial of patients with sepsis but low risk of death (ADDRESS) was recently stopped by the Data Safety … May 26, 2021
WebM&M Cases
Fatal Patient-Controlled
-
psnet.ahrq.gov/node/861838/psn-pdf
January 31, 2024 - evaluate the telephone surveillance system, Brigham and Women’s Hospital system conducted a
cluster randomized … trial, Calling for Earlier Detection of Adverse Reactions (CEDAR). … Screening for adverse drug events: a randomized trial of
automated calls coupled with phone-based pharmacist
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/lung-cancer-screening
March 09, 2021 - Standardization of LDCT Screening and Follow-up of Abnormal Findings
The randomized clinical trials … Reduced lung-cancer mortality with volume CT screening in a randomized trial. … Screening by chest radiograph and lung cancer mortality: the Prostate, Lung, Colorectal, and Ovarian (PLCO) randomized … trial. … Systematic review and meta-analysis of randomized and nonrandomized trials on safety and efficacy of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-rehospitalization_research.pdf
November 01, 2007 - Placebo-controlled randomized trials have demonstrated the efficacy of selected β-
blockers on outcomes … The COMET randomized trial compared carvedilol (25 mg per day) against metoprolol
tartrate (50 mg twice … A small randomized, non-blinded trial in Serbia of 150 patients
with heart failure being treated with … with heart failure: the Metoprolol CR/XL
Randomized Intervention Trial in congestive
heart failure … (COMET): randomised controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
September 13, 2012 - wound dressings are classified as devices
and not drugs, the FDA does not require rigorous clinical trial … of Methodological Quality of Individual Studies
Article quality will be assessed differently for randomized … dichotomous outcomes, we will
calculate a pooled effect estimate of the relative risk between the trial … Food and Drug Administration
PTFE = polytetrafluoroethylene
RCT = randomized controlled trial
RFA … • We will include randomized controlled trials and observational studies with a
concurrent comparison
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan15/depression-in-children-and-adolescents-screening
September 15, 2013 - with a Human Development Index of low to high
Study Designs
KQs 1, 3, 4–6:
Randomized … , controlled trials
Controlled clinical trials
Systematic reviews published since 2011
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-cancer_clinician.pdf
July 01, 2017 - hazard ratio; Inst = institutional cohort studies; N = number of subjects; NA = not applicable; RCT = randomized … controlled trial;
RR = risk ratio; SEER = Surveillance, Epidemiology, and End Results; SOE = strength … estimated glomerular filtration rate;
ESRD = end-stage renal disease; N = number of subjects; RCT = randomized … controlled trial; Ret = retrospective study;
RR = risk ratio; SOE = strength of evidence; WMD = weighted
-
www.ahrq.gov/hai/pfp/interimhac2013-ref.html
December 01, 2014 - Reduction of urinary tract infection and antibiotic use after surgery: A controlled, prospective, before-after … frequent dressing changes for prevention of catheter-related infections in critically ill adults, a randomized … controlled trial. … Fall prevention in acute care hospitals: a randomized trial. JAMA 2010;304(17):1912-8.
-
www.ahrq.gov/hai/pfp/hacrate2013-refs.html
October 01, 2015 - Reduction of urinary tract infection and antibiotic use after surgery: A controlled, prospective, before-after … frequent dressing changes for prevention of catheter-related infections in critically ill adults, a randomized … controlled trial. … Fall prevention in acute care hospitals: a randomized trial. JAMA 2010;304(17):1912-8.
-
digital.ahrq.gov/sites/default/files/docs/coordination-patients-complex-needs-slides-022014.pdf
February 20, 2014 - of health care service
6
The Chronic Care Model
7
Study Design
• 18-month prospective controlled … integrated into
the electronic health record
o Patient educational material
• Nurses kept their randomized … McDonald
et al., JAMIA 2013; 20:499-505.
34
Analysis
• Intent-to-treat analysis from cluster randomized … trial
► Comparison of patient outcomes between usual care
and intervention groups
• Intervention … :
Intent-to-Treat Analysis
39
CDS USE ANALYSIS
40
CDS Use Analysis
• CDS use was not randomized
-
www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/genital-herpes-serologic-screening
December 02, 2021 - immunodeficiency virus; HSV=herpes simplex virus; KQ=key question; PCR=polymerase chain reaction; RCT=randomized … , controlled trial
Response to Public Comment
-
www.ahrq.gov/hai/tools/mvp/modules/vae/surveillance-slides.html
February 01, 2017 - In randomized controlled trials, VAP interventions have been shown to improve objective outcomes, such