-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer18-heart-disease-ace-inhibitor-arb-executive.pdf
October 01, 2009 - The TRANSCEND (Telmisartan Randomized
AssessmeNt Study in ACE iNtolerant subjects with
cardiovascular … Disease) trial was the only placebo-
controlled trial available to evaluate major efficacy
outcomes … Since
ONTARGET directly compared the same drugs as were
evaluated in the placebo-controlled HOPE and … For our base
case analysis, we limited the trials to randomized,
double-blinded comparisons of ACE inhibitors … • Either (1) an individual patient data meta-analysis
of major placebo-controlled ACE inhibitor or
-
psnet.ahrq.gov/web-mm/antibiotics-urisinusitis-simple-decision-gone-bad
January 01, 2014 - A recent cluster-randomized trial using a handheld computer–based decision support system for prescribing … Clinical decision support and appropriateness of antimicrobial prescribing: a randomized trial. … A randomized controlled trial of an educational intervention with internal medicine residents.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_disposition-comments.pdf
January 01, 2012 - 10
Commentator
& Affiliation
Section Comment Response
not so true in the typical five-year randomized … clinical trial done in
the 19702, 1980s and 1990s which established utility of treating
blood pressure … Page 88 subgroups, this was an a priori separately randomized
group, and the relative risk you provided … reader
to page and section number in text that discusses this point
We did not include the numbers randomized
-
psnet.ahrq.gov/node/61079/psn-pdf
October 28, 2020 - almost immediately in 81 of these patients.6-7 Since these documented reports, there
have been no randomized … controlled trials studying chlorpromazine for hiccups. … A Randomized Controlled Trial.?Arch Intern
Med.?
-
psnet.ahrq.gov/sites/default/files/import/webmm.ahrq.gov.60_slideshow.ppt
May 01, 2004 - Abstract
Intensive Insulin Therapy in the Critically Ill Patient
1500 critically ill patients randomized … lower rates of adverse events than seen in practice
Patients rarely monitored as closely outside of trial … inclusion criteria can lead to a lesser benefit in actual practice (effectiveness) than that seen in the trial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
March 05, 2015 - Research gaps: should call for rigorous comparative effectiveness
pbo-controlled trials that simultaneously … For
example, results of 3 arm placebo controlled trial of low dose estradiol
(0.5 mg dose equivalent … Because of a belief that randomized clinical trials trump all
other research methods, an extensive body … While there are not adequate randomized controlled trials to prove all
of this, and never will be – … That randomized controlled trials are the most valid
approach to estimating causal effects is not debated
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/quality-gap-palliative-hospice_executive.pdf
October 01, 2012 - Assessing Risk of Bias from
the Cochrane Handbook for Systematic Reviews of
Interventions for assessing randomized … controlled trials.11
Data abstraction forms were not developed for this phase
of the review, and elements … tools that worked well in
this literature and could be compared with risk-of-bias tools
designed for randomized … Twelve studies were randomized controlled
trials (RCTs). … Low
Low
Low
Low
aStrength of evidence is based mainly on the strength of the study designs (with randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/appendicitis_research-protocol.pdf
December 09, 2013 - (2) Randomized controlled trials of alternative testing strategies including at least 10
patients … controlled trials we will use the
Cochrane Risk of Bias tool.54
We will not calculate “composite … Thus, randomized controlled trials will be graded as having a high,
medium, or low risk of bias, and … However, we also expect to find a small number of
parallel group, randomized or non-randomized, comparative … We will not combine
the results of randomized and non-randomized studies statistically.
-
digital.ahrq.gov/funding-mechanism/ahrq-health-services-research-demonstration-and-dissemination-grants-r18
January 01, 2023 - Disseminating and Implementing MedSMA℞T Families in Emergency Departments: A Randomized … Control Trial to Assess Effectiveness of an Evidence-Based Gaming Intervention to Reduce Opioid Misuse … with electronic health record tools in a primary care setting: Baseline results from the MAINTAIN-pc trial … with electronic health record tools in a primary care setting: Baseline results from the MAINTAIN-pc trial
-
psnet.ahrq.gov/issue/optimizing-patient-handoff-between-ems-and-emergency-department
April 24, 2018 - April 24, 2018
Education outcomes from a duty-hour flexibility trial in internal medicine … sleep period on hours slept during extended overnight in-hospital duty hours among medical interns: a randomized … trial. … October 30, 2013
Design and trial of a new ambulance-to-emergency department handover
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - = Key Question; PICOTS = population, interventions, comparators, outcomes, timing, setting; RCT =
randomized … controlled trial
III. … controlled trials (RCTs) of at least one-
month duration. … of Individual Studies
Predefined criteria will be used to assess the risk of bias of individual controlled … Randomized trials will be evaluated using criteria
and methods developed by the Cochrane Back Review
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
September 01, 2011 - One of the more important
aspects I believe is funding source, and only the randomized clinical
trials … Brief included the RCT (Wenstrom,
Guinn) which, due to their small populations (only 94 who were
randomized … The level of maternity care however (excluding the two
randomized clinical trials) were always reported … Placebo controlled studies of adequate power to
evaluate outcomes of primary importance (newborn morbidities … This is simply not true if the
randomized clinical trials are deleted and the other data is imported
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1512.pdf
December 01, 2015 - controlled SCALE™ trial.64 The trial randomly assigned
patients without diabetes who were overweight … controlled study. … The
REDUCE pivotal trial: a prospective,
randomized controlled pivotal trial of a dual
intragastric … Effects
of liraglutide in the treatment of obesity: a
randomised, double-blind, placebo-controlled … A
randomized, controlled trial of 3.0 mg of
liraglutide in weight management.
-
psnet.ahrq.gov/node/49648/psn-pdf
March 01, 2012 - Comprehensive discharge planning and home follow-up of
hospitalized elders: a randomized clinical trial … The care transitions intervention: results of a randomized
controlled trial. … A reengineered hospital discharge program to decrease
rehospitalization: a randomized trial.
-
psnet.ahrq.gov/sites/default/files/2024-07/spotlight_case_mismanagement_of_acute_decompensated_heart_failure_slides_final.pptx
January 01, 2024 - In this patient’s case, after two doses of IV labetalol controlled the blood pressure, she appeared to … Clevidipine for severe hypertension in acute heart failure: a VELOCITY trial analysis. … text]
Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial … the morbidity of patients with severe chronic heart failure: results of the carvedilol prospective randomized … Adverse Effects of β-Blocker Therapy for Patients With Heart Failure: A Quantitative Overview of Randomized
-
www.ahrq.gov/sites/default/files/2024-01/fernandez-rosenman-report.pdf
January 01, 2024 - Key Words: team leadership, trauma resuscitations, patient safety, randomized controlled trial
B. … METHODS
We executed an individual, randomized controlled trial. … A total of 79 subjects consented and were randomized (Figure 3). … This represents the first rigorous, randomized, controlled trial of a leadership or teamwork-
focused … controlled trial. 2018 Society for Academic Emergency
Medicine, Indianapolis, IN.
5.
-
www.uspreventiveservicestaskforce.org/uspstf/recommendation/lipid-disorders-in-children-screening
July 18, 2023 - The review included 10 fair- to good-quality randomized clinical trials (n = 1230) of statins, with follow-up … The largest trial (n = 214), with 2-year follow-up, reported no cases in the statin group and only 2 … In the 10-year observational follow-up of this trial, elevated liver enzyme levels at this threshold … However, these studies were limited and had short trial durations of 5 to 16 weeks. 1 , 17
How Does … A new 20-year follow-up study (n = 214) from a randomized clinical trial of children and their parents
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - Central Register of
Controlled Trials, ClinicalTrials.gov, Current Controlled
5
Fi
g
u
re
A
. … We rated the quality of each randomized trial based on the
methods used for randomization, allocation … Clinical outcomes or spread of disease:
Counseling
Insufficient One randomized trial found a self-management … Such studies are more susceptible
to bias and confounding than well-conducted randomized
trials. … A randomized intervention
trial to reduce the lending of used injection equipment among
injection drug
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/QaNSteuunshjz-kHPxVvAN
April 27, 2021 - STUDY SELECTION Randomized clinical trials (RCTs) and nonrandomized controlled
intervention studies for … disease (CVD).1-3 Blood
pressure can be modified with lifestyle interventions,4-6
and good-quality randomized … Randomised controlled trial of treatment for
mild hypertension: design and pilot trial: report of
Medical … Impact of diagnosis and treatment of hypertension
on quality of life: a double-blind, randomized,
placebo-controlled … Blood pressure checks and diagnosing
hypertension (BP-CHECK): Design and methods of
a randomized controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_executive.pdf
April 01, 2013 - Gray literature databases included
ClinicalTrials.gov; metaRegister of Controlled Trials;
ClinicalStudyResults.org … requiring reporting
intermediate-term and long-term patient outcomes had
the effect of eliminating randomized … – Consider controlled trials in children. … • The duration of controlled trial efficacy data are
limited. … head-to-head treatment or combo
versus monotherapy trials), longer term followup
studies that retain randomized