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psnet.ahrq.gov/node/47681/psn-pdf
January 30, 2019 - quantification-anesthesia-providers-hand-hygiene-busy-metropolitan-operating-room-what-would
https://psnet.ahrq.gov/issue/double-gloves-randomized-trial-evaluate-simple-strategy-reduce-contamination-operating-room
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effectivehealthcare.ahrq.gov/sites/default/files/dementia-agitation-aggression_disposition-comments.pdf
March 21, 2016 - We agree that conducting randomized controlled trials
(RCT) for nonpharmacologic interventions is challenging … I think a major methodological flaw is the use
of randomized controlled trials. … Gonyea, J., O’Connor, M., and Boyle, P. (2006) “Project CARE: A
randomized controlled trial of a behavioral … A Randomized controlled trial of a community-
based dementia care coordination intervention: Effects … Our reviewed included two randomized controlled trials that
evaluated emotion-oriented care (total n
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www.ahrq.gov/sites/default/files/2024-01/lambert-report.pdf
January 01, 2024 - Similarly, data from our health literacy randomized trial are still
being analyzed, but preliminary … trial out of a longitudinal observational dataset. … Benefits from antidepressants: Synthesis of 6-week
patient-level outcomes from double-blind placebo controlled … randomized trials of fluoxetine and
venlafaxine. … Controlled Studies of Fluoxetine and Venlafaxine.
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digital.ahrq.gov/events/national-web-conference-using-health-it-chronic-disease-management
January 01, 2023 - Fricton will present findings from a randomized clinical trial (RCT) of clinical decision support (CDS … The three-arm, 2-year, prospective, group-randomized clinical trial was implemented in 160 health care
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-informed-care-executive-summary.pdf
January 01, 2025 - ), APA PsycInfo® (via Ovid),
CINAHL®, ERIC (via EBSCOHost), and Scopus (Elsevier B.V.) to identify randomized … controlled trials (RCTs) and comparative nonrandomized studies of interventions
(NRSIs) published … availability of a sufficient number of organizational units for
randomization required for a gold-standard randomized … trial.
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digital.ahrq.gov/ahrq-funded-projects/interactive-preventive-health-record-iphr-promote-patient-centered-care/annual-summary/2011
January 01, 2011 - The project team used this randomized controlled trial to examine the effects of MyPreventiveCare on
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/making-healthcare-safer-IV.pdf
August 04, 2023 - facilities
Ambulatory, community, or other
outpatient settings
Type of studies Original studies (Randomized … controlled trials or
observational studies with a
comparison group, including
pre-post studies), … the primary reviewer will use the Cochrane
Collaboration’s tool for assessing the risk of bias of randomized … controlled trials (RCTs) or the
ROBINS-I tool for assessing the Risk Of Bias In Non-randomized Studies … bias, detection bias, attrition bias, reporting bias, and
8
other bias.17 When assessing non-randomized
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-2005
July 11, 2005 - may be maintained or improved after 5 to 10 years in a subset of patients. 29 , 30
One fair-quality randomized … controlled trial (RCT) compared a reduced-glycemic-load diet with a conventional-reduced-fat diet in … Among 4 recent behavioral intervention trials, adverse effects were reported in 1 trial. 33 Among those … During the placebo-controlled phase of the sibutramine trial, 19 of 43 patients (44%) in the group receiving … Behavior therapy and sibutramine for the treatment of adolescent obesity: a randomized controlled trial
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/J-vUTejXWsdp_d86zK4Gth
July 01, 2005 - However, few of these studies controlled for adult
BMI, thereby limiting the independent predictive … maintained or improved after 5 to 10
3
years in a subset of patients.29,30 One fair-quality randomized … controlled trial (RCT)
compared a reduced-glycemic-load diet with a conventional-reduced-fat diet in … During the placebo-controlled
phase of the sibutramine trial, 19 of 43 patients (44%) in the group receiving … Behavior therapy and
sibutramine for the treatment of adolescent
obesity: a randomized controlled trial
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-loss-surgery_executive.pdf
June 01, 2013 - Study/literature flow diagram
BMI = body mass index; RCT = randomized controlled trial
6
suggested … We rated the overall evidence as moderate due to
sparseness of data—three randomized controlled trials … A recent U.S. trial
comparing these same procedures found similar results. … Randomized controlled trials are considered the highest
level of medical evidence. … We found one trial and one cohort study comparing
procedures performed in the United States.
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psnet.ahrq.gov/web-mm/compare-and-contrast
July 16, 2019 - clinical trial found that iodixanol, an iso-osmolar agent, was less nephrotoxic than low-osmolar iohexol … because of the lingering questions regarding N-acetylcysteine’s true benefits in preventing CN, a recent trial … ( 12 ) One hundred and nineteen subjects with baseline serum creatinine greater than 1.1 mg/dL were randomized … The largest hemodialysis trial randomized subjects to a single hemodialysis session following contrast … Prevention of contrast-induced nephropathy with sodium bicarbonate: a randomized controlled trial.
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psnet.ahrq.gov/node/49478/psn-pdf
April 01, 2005 - traditional agents found a reduced risk of CN in patients with
chronic kidney disease.(7) A recent randomized … clinical trial found that iodixanol, an iso-osmolar agent, was
less nephrotoxic than low-osmolar iohexol … .(12) One hundred and nineteen
subjects with baseline serum creatinine greater than 1.1 mg/dL were randomized … The largest
hemodialysis trial randomized subjects to a single hemodialysis session following contrast … Prevention of contrast-induced nephropathy with sodium
bicarbonate: a randomized controlled trial.
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psnet.ahrq.gov/node/865778/psn-pdf
May 29, 2024 - Hospital Medicine.3 In the largest published meta-analysis, involving 5,108 patients enrolled in
35 randomized … or quasi-randomized controlled trials,4 use of two-dimensional ultrasound guidance reduced
the overall … ultrasound guidance for the placement of
hemodialysis catheters: a systematic review and meta-analysis of randomized … controlled trials.
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psnet.ahrq.gov/web-mm/impatient-inpatient-dosing
June 24, 2020 - Evaluation of a decision support system for initiation and control of oral anticoagulation in a randomised trial … Warfarin dosage requirements: prospective clinical trial of a method for prediction from the response … A randomized, controlled trial in a teaching hospital. … A randomized trial comparing 5-mg and 10-mg warfarin loading doses. … June 24, 2020
WebM&M Cases
Fatal Patient-Controlled
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psnet.ahrq.gov/web-mm/nonsustained-ventricular-tachycardia-after-acute-coronary-syndromes-recognizing-high-risk
September 20, 2011 - Recent findings from a large clinical trial of patients with non-ST elevation myocardial infarction ( … non-ST-elevation acute coronary syndrome-thrombolysis in myocardial infarction 36 (MERLIN-TIMI 36) randomized … controlled trial. … Multicenter randomized trial and a systematic overview of lidocaine in acute myocardial infarction.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/unhealthy-alcohol-use-adolescents-adults-behavioral-counseling-interventions
May 16, 2024 - compare individuals who receive screening with those receiving no screening or usual care, including randomized … , controlled trials and nonrandomized controlled trials (i.e., longitudinal studies with concurrent comparisons … sensitivity and specificity compared with a structured or semistructured clinical interview KQs 4, 5: Randomized … , controlled trials
Other study designs
Country
Studies conducted in countries categorized
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psnet.ahrq.gov/node/49437/psn-pdf
March 01, 2004 - the operating
physician reported excessive bleeding from the catheter site, but this was eventually controlled … Complications of femoral and subclavian venous catheterization
in critically ill patients: a randomized … controlled trial. … central venous catheter-related bloodstream
infection by use of an antiseptic-impregnated catheter: a randomized … , controlled trial.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/skin-cancer-screening-2001
April 01, 2001 - No controlled studies have shown that formal screening programs will improve this already high cure rate … We did not find direct evidence from controlled studies of the effect of screening on health outcomes … A recent review by Elwood 65 examined the options for conducting a randomized trial of screening in … II–1,III
Fair: There are no controlled studies of treatment in patients found by screening to have … *I: Randomized controlled trial; II–1: Controlled trial without randomization; II–2: Cohort or case-control
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-iv-nv-hap-protocol.pdf
August 05, 2024 - controlled trial; U.S. = United States
Literature Searches
Our search strategy will focus on databases … the
primary reviewer will use the Cochrane Collaboration’s tool for assessing the risk of bias
of randomized … controlled trials (RCTs) or the ROBINS-I tool for assessing the Risk Of
Bias In Non-randomized Studies … Oral Care in Individuals
Without Mechanical Ventilation: A
Systematic Review and Meta-Analysis of
Randomized … Controlled Trials.
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effectivehealthcare.ahrq.gov/sites/default/files/10_obesity_potential_high_impact_june_2012.pdf
January 01, 2012 - *Controlled release phentermine/topiramate (Qnexa) for treatment of obesity High
2. … This study is
an extension of a phase III, clinical trial (CONQUER). … 3 trial. … A
multicenter, randomized efficacy study of the
EndoBarrier gastrointestinal liner for presurgical … Open-
label, sham-controlled trial of an endoscopic
duodenojejunal bypass liner for preoperative weight