Results

Total Results: 1,014 records

Showing results for "randomized controlled trial".

821. Evidence Summary: Skin Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/skin-cancer-screening
     April 18, 2023 - countries categorized as “very high” on the 2019 Human Development Index. 12 Eligible study designs were randomized … Limitations The lack of individual-level or trial data on the effectiveness of skin cancer screening … In the absence of randomized studies, the body of evidence from nonrandomized studies would be strengthened … stage/thickness at detection and health outcomes 0 9 9 1,326,051 Study design    Randomized … studies) Melanoma mortality: consistent, imprecise Low for limited to no mortality benefit No randomized

822. Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/pth_4-Mnau_pZubaefDvUk
     January 01, 2020 - The best estimates from randomized, con- trolled trials (RCTs) evaluating the effect of mammogra- phy … Avoided (95% CI) per 10 000 Women Screened by Repeat Screening Mammography Over 10 Years: Data From Randomized … , Controlled Trials* Variable Ages 40–49 y Ages 50–59 y Ages 60–69 y Ages 70–74 y Breast cancer deaths … , controlled trials. … In addi- tion, long-term randomized trials or longitudinal cohort studies are needed that compare screening

823. Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/vTJ_Zj3TAkhx45wWUDtNyt
     May 01, 2021 - As noted, most trials had a mean participant age in the 50s and 60s; only 1 trial, PROSPER (n = 3239 … Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial … statin treatment vs usual care on primary cardiovascular prevention among older adults: the ALLHAT-LLT randomized … clinical trial. … Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs

824. JAMA (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/DQgVKNYn6gFtXLfwthuRBU
     June 12, 2020 - error, cataracts, or AMD (3 stud- ies; n = 5203).13,33 Benefits of Early Detection and Treatment Four randomized … surgery) and cataract surgery are effective treatments for refractive errors and cataracts.27 Four randomized … and cardiovascular adverse events were infrequent and oc- curred in similar proportions of patients randomized … omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized … clinical trial.

825. Prevention of Dental Caries in Preschool Children - Recommendations and Rationale (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/TuWmfBsDp6S9NXjTHNdGou
     April 01, 2004 - that only 22% of pediatricians were familiar with fluoride varnish.12 Four of 6 trials, including 3 randomized … controlled trials, found statistically significant reductions in the number of tooth surfaces with cavitated … Community-oriented oral health promotion for infants in Jerusalem: evaluation of a program trial.

826. Archived: Carotid Artery Stenosis: Screening, December 2007 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/carotid-artery-stenosis-screening-december-2007
     December 15, 2007 - Good evidence indicates that in selected, high-risk trial participants with asymptomatic severe CAS, … evidence on the natural history of CAS, systematic reviews of the accuracy of screening tests, and randomized … , controlled trials (RCTs) of the benefits of treatment of CAS with carotid endarterectomy. … strokes by successful carotid endarterectomy in patients without recent neurological symptoms: randomised controlled … trial.

827. Screening for Speech and Language Delay and Disorders in Children 5 Years or Younger: Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/6tmQG7VgexjoXt7uNoyccj
     December 02, 2023 - Randomized clinical trials (RCTs), nonrandomized clinical trials, and controlled cohort studies were … Cluster-randomized controlled trial evaluating the effectiveness of computer-assisted intervention delivered … a randomized control trial. … Effectiveness of speech intervention for phonological disorders: a randomized controlled trial. … Randomised controlled trial of the Lidcombe Programme of Early Stuttering Intervention.

828. Archived: Obesity in Children and Adolescents: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-children-and-adolescents-screening-june-2017
     June 20, 2017 - threshold for clinically important change. 3 An analysis by Epstein et al of 10-year outcomes from 4 randomized … Ten of these trials were fair quality, and the remaining trial was good quality. … Most pharmacotherapy trials only followed up participants for 6 months. 3 Only 1 trial assessed the … No metformin trials reported health outcomes. 3 One trial demonstrated that the effect of metformin … Ten trials were fair quality, and the remaining trial was good quality.

829. Overdiagnosis in Prostate Cancer Screening Decision Models: A Contextual Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/KT7vaWK_JSDNNvEmUAjN8d
     May 01, 2018 - Uncertainties regarding the benefit of PSA screening in reducing prostate cancer mortality in randomized … They used their model and information from the Health Insurance Plan (HIP) randomized trial of breast … Studies of overdiagnosis based on randomized trials and population studies use the excess incidence … trial for those assigned to the control group, the duration of screening in the trial, the amount of … continued screening after trial end for those assigned to be screened within the trial, the uptake

830. Overdiagnosis in Prostate Cancer Screening Decision Models: A Contextual Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/Home/GetFile/1/16812/prostate-models-overdiagnosis/pdf
     May 01, 2018 - Uncertainties regarding the benefit of PSA screening in reducing prostate cancer mortality in randomized … They used their model and information from the Health Insurance Plan (HIP) randomized trial of breast … Studies of overdiagnosis based on randomized trials and population studies use the excess incidence … trial for those assigned to the control group, the duration of screening in the trial, the amount of … continued screening after trial end for those assigned to be screened within the trial, the uptake

831. Final Research Plan: Latent Tuberculosis Infection in Adults: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/latent-tuberculosis-infection-screening
     June 17, 2021 - question; LTBI=latent tuberculosis infection; PPD=purified protein derivative; QFT=QuantiFERON; RCT=randomized … , controlled trial; RIF=rifampin; RPT=rifapentine; TB=tuberculosis; TNF-α=tumor necrosis factor-α; T-SPOT

832. Screening for Depression and Suicide Risk in Children and Adolescents: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/_2-KL_eHkuBhbGrzcAHsB-
     June 01, 2022 - Thirteen randomized clinical trials (RCTs) (n = 2156) ad- dressed the benefits of depression treatment … combination for adolescents with depression: Treatment for Adolescents With Depression Study (TADS) randomized … controlled trial. … SPARX, a computerised self help intervention for adolescents seeking help for depression: randomised controlled … non-inferiority trial.

833. Archived: Colorectal Cancer: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening-june-2016
     June 15, 2016 - Adherence to colorectal cancer screening: a randomized clinical trial of competing strategies. … Effect of flexible sigmoidoscopy screening on colorectal cancer incidence and mortality: a randomized … clinical trial. … The NordICC Study: rationale and design of a randomized trial on colonoscopy screening for colorectal … clinical trial.

834. Recommendation: Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
     September 28, 2021 - Benefits of Risk Assessment and Preventive Medication The USPSTF considered 18 randomized clinical … RCTs (n = 15,767; 10 good-quality) to assess prevention of preeclampsia. 1 All trials were placebo-controlled … were included with trials of participants at increased risk (16 trials). 1 All trials were placebo-controlled … Follow-up data from the largest trial, the Collaborative Low-dose Aspirin Study in Pregnancy (CLASP), … CLASP: a randomised trial of low-dose aspirin for the prevention and treatment of pre-eclampsia among

835. Screening for Gestational Diabetes Mellitus: U.S. Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/9K4QQKvhXZNJLCxNX3FkZm
     May 01, 2008 - Gestation Although screening and early treatment of gestational diabetes reduce macrosomia, and although 1 trial … In addition, further randomized trials comparing the health outcomes of lowering glucose with the health … The Maternal-Fetal Medicine Units network is conducting a randomized, controlled trial (RCT) now in progress … Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group.

836. Recommendation: Weight Loss to Prevent Obesity-Related Morbidity and Mortality in Adults: Behavioral Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/obesity-in-adults-interventions
     September 18, 2018 - Program lifestyle intervention for use in a primary care or community setting. 1 Study heterogeneity, trial … Only 1 trial delivered its intervention through print-based tailored materials. 1 Rates of participant … One trial enrolled participants with cardiovascular risk factors. 1 Trial sample sizes ranged from 92 … was limited to women, and 1 trial was limited to men. … In the good-quality Diabetes Prevention Program trial (n = 1295), the estimated cumulative incidence

837. Behavioral Counseling Interventions to Promote a Healthful Diet and Physical Activity for CVD in Adults: USPSTF Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/2_e9yUNkzrtkkNKmn7YtCU
     September 01, 2012 - The largest (n � 48 835) and highest-quality random- ized trial of healthful diet counseling (specifically … , a low-fat diet), the Women’s Health Initiative (WHI) Dietary Mod- ification Trial, showed significant … Low-fat dietary pattern and risk of cardiovascular disease: the Women’s Health Initiative Randomized … Controlled Dietary Modification Trial.

838. Screening for Bladder Cancer: A Brief Evidence Update (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/NZcLsqV-5K7hyfot-qHQp9
     November 01, 2004 - Finally, we combined bladder neoplasms with randomized controlled trial and then combined those results

839. JAMA JATS (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/Nop5YpEpMybx_oNPKC76-X
     July 11, 2017 - In- terventions that focused on supervised exercise or controlled diets were not included. … Hypertension Prevention Trial Research Group. … pattern and risk of treated diabetes mellitus in postmenopausal women: the Women’s Health Initiative randomized … controlled dietary modification trial. … trial.

840. Archived: Depression: Screening 2002 | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/depression-screening-2002
     May 07, 2002 - Effectiveness of Screening The review for the USPSTF identified 14 randomized, controlled trials that … One trial, which included both newly detected cases of depression and patients already under treatment