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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6W538pkN7ft6TsRMKfPWMJ
May 27, 2014 - Low dose
aspirin for the treatment of fetal growth restriction: a randomized controlled trial. … A randomized controlled trial of low-dose aspirin in women at risk from
pre-eclampsia. … controlled clinical trial. … Low dose aspirin for the treatment of fetal growth
restriction: a randomized controlled trial. … A prospective randomized placebo-controlled trial of low-dose aspirin for prevention of
intra-uterine
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/genital-herpes-screening-2005
March 15, 2005 - Three good-quality randomized controlled trials (RCTs) and one fair-quality RCT examined the effectiveness … A good-quality, randomized, multi-center, placebo-controlled trial showed that once-daily valacyclovir … Oral famciclovir for the suppression of recurrent genital herpes: a randomized controlled trial. … A multicenter, double-blind, placebo-controlled trial. … A randomised placebo-controlled trial of suppressive acyclovir in late pregnancy in women with recurrent
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/obesity-in-adults-interventions
March 31, 2016 - of the Organisation for Economic Co-Operation and Development
Study designs
KQs 1, 2: Randomized … or controlled clinical trials, including cluster randomized trials
KQ 3:
Systematic reviews, … including meta-analyses, of randomized or controlled clinical trials or cohort studies
Randomized … or controlled clinical trials, including cluster randomized trials
Large cohort or case-control studies
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prostate-cancer-screening
April 28, 2016 - , controlled trials; systematic reviews (of included study designs); meta analyses
KQs 2–5: Randomized … , controlled trials; cohort studies; uncontrolled observational studies of harms ‡
Other study designs … , controlled trials; cohort studies; and larger uncontrolled studies are not available … Mortality results from a randomized prostate-cancer screening trial. … Screening and prostate-cancer mortality in a randomized European study.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan154/healthful-diet-and-physical-activity-for-cardiovascular-disease-prevention-in-adults-without-known-risk-factors-behavioral-counseling-july-2017
May 14, 2015 - tolerance, smoking); adults at high risk for CVD based on a cardiovascular risk assessment tool; or trial … specialists, dietitians, nutritionists, and behavioral health specialists
Supervised exercise
Controlled … Abbreviations: CCT = controlled clinical trial; RCT = randomized, controlled trial.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan21/chlamydia-and-gonorrhea-screening-september-2014
June 15, 2013 - clinics)
Study Designs
All KQs: Good-quality systematic reviews
Benefits: Randomized … , controlled trials, controlled observational trials
Harms: Randomized, controlled trials, controlled
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/lipid-disorders-in-adults-cholesterol-dyslipidemia-screening-2001
April 09, 2001 - controlled trial that examined the effect of early screening and treatment (compared with delayed screening … A metaanalysis of randomized controlled trials. Am J Public Health 1997;87:1415–22.
47. … A randomized trial to evaluate the effectiveness of dietary advice by practice nurses in lowering diet-related … Randomised controlled trial in northern England of the effect of a person knowing their own serum cholesterol … Health checks and coronary risk: further evidence from a randomised controlled trial.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/q_zxLD9JZFGoSPCrEHNk2g
June 11, 2019 - DATA SOURCES Ovid MEDLINE, the Cochrane Central Register of Controlled Trials,
and the Cochrane Database … STUDY SELECTION Nonpregnant individuals 12 years and older; randomized clinical trials
(RCTs) and controlled … in
low/middle-income settings
Median CD4 cell count was
651/mm3 in one trial, and in the
other trial … the phase 3 HPTN 052 randomised controlled trial. … trial.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/pnyU5fxhdBUtCdvJ3GyqzR
March 01, 2007 - Randomized, controlled trials (RCTs); controlled clin-
ical trials; and observational studies (cohort … ASA � aspirin; CRA � colorectal adenoma; CRC � colorectal cancer; RCT � randomized, controlled trial. … , controlled trial; RR � relative risk. … Low-dose
aspirin and incidence of colorectal tumors in a randomized trial. … , controlled trial; U.S. � United States.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/za7BqXMwT8BMz4Z_ygrvKm
May 01, 2004 - cancer.8,9
Most women with ovarian cancer have
non-localized disease at the time of diagnosis.4 A
randomized … controlled trial (RCT) using multi-
modal screening (CA-125 screening, followed by
ultrasound for abnormally … ; and the European Randomized Trial of
Ovarian Cancer Screening.19–21
Recommendations of Other
Groups … Screening
for ovarian cancer: a pilot randomised controlled
trial. … European randomized trial of ovarian
cancer screening (protocol).
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/gestational-diabetes-screening
June 06, 2019 - Prospective cohort studies, single arms of trials
KQ 5: Observational studies and single-arm trials (i.e., trial … arms not receiving treatment)
KQs 6, 7: RCTs, CCTs; controlled observational studies, if no trials … Abbreviations: CCT=controlled clinical trial; FPG=fasting plasma glucose; GDM=gestational diabetes mellitus … neonatal intensive care unit; OGCT=oral glucose challenge test; OGTT=oral glucose tolerance test; RCT=randomized … , controlled trial.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/intimate-partner-violence-and-abuse-of-elderly-and-vulnerable-adults-screening-october-2018
October 23, 2018 - An intervention to improve postpartum outcomes in African-American mothers: a randomized controlled trial … Domestic violence enhanced perinatal home visits: the DOVE randomized clinical trial. … Reducing maternal intimate partner violence after the birth of a child: a randomized controlled trial … An integrated intervention to reduce intimate partner violence in pregnancy: a randomized controlled … controlled trial.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-pregnant-women/human-immunodeficiency-virus-hiv-infection-screening
June 15, 2017 - infection and in which management of HIV infection is similar to that in the United States, except for randomized … and metabolic maternal outcomes
KQs 1, 5: Pharmacokinetic outcomes
Study designs
KQs 1–4: Randomized … , controlled trials and controlled observational studies
KQ 5: Randomized trials and controlled
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary25/folic-acid-to-prevent-neural-tube-defects-preventive-medication-2009
May 15, 2009 - Study Selection: English-language randomized, controlled trials; cohort studies; case–control studies … Conclusion: New observational evidence supports previous evidence from a randomized, controlled trial … Hungarian cohort-controlled trial of periconceptional multivitamin supplementation shows a reduction … , controlled trial. … , controlled trial
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/abdominal-aortic-aneurysm-screening
November 30, 2017 - i.e., serious adverse events from pharmacotherapy or surgery)
Study Designs
KQs 1, 4: Randomized … , controlled trials
KQs 2, 3: Randomized, controlled trials; large cohort studies (sample size > … 1,000)
KQ 5: Randomized, controlled trials; large cohort studies (sample size >1,000); vascular surgery
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-aspirin-to-prevent-cancer/aspirin-to-prevent-cardiovascular-disease-and-cancer-april-2016
October 07, 2013 - Recurrence
KQs 6, 7 (harms):
Postoperative or minor bleeding
Study Design
KQs 1–5:
Randomized … , controlled trials
Controlled clinical trials
Systematic reviews and meta-analyses of randomized … , controlled trials for evidence on benefits
KQs 6, 7:
Randomized, controlled trials
Controlled
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan108/folic-acid-for-the-prevention-of-neural-tube-defects-preventive-medication-january-2017
October 16, 2014 - periconceptional period on neural tube defects differ by medical risk factors (i.e., obesity, poorly controlled … categorized as “Very High” on the Human Development Index
Study designs
Efficacy (KQ 1): Randomized … , controlled trials; controlled clinical trials; cohort or case-control studies
Harms (KQ 2): … Randomized, controlled trials; controlled clinical trials; or observational studies (case-control, cohort
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/latent-tuberculosis-infection-screening
May 02, 2023 - For treatment of LTBI, a large (n = 27,830), good-quality randomized clinical trial found a relative … Interaction between C-Tb and PPD given concomitantly in a split-body randomised controlled trial. … A controlled trial of isoniazid prophylaxis in mental institutions. … Long-term isoniazid prophylaxis: controlled trial on INH prophylaxis after recent tuberculin conversion … An open label, randomised controlled trial of rifapentine versus rifampicin based short course regimens
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/tobacco-and-nicotine-use-prevention-in-children-and-adolescents-primary-care-interventions
October 12, 2017 - issues)
Attitudes or knowledge about tobacco; intentions to quit
Study Design
KQs 1, 2:
Randomized … and nonrandomized, controlled trials; systematic reviews
Trials with a minimum of 6 months (or 24 … weeks) of followup postbaseline
KQ 3:
Randomized and nonrandomized, controlled trials; comparative
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/skin-cancer-screening
March 25, 2021 - nonmelanoma skin cancers)
Study design
All KQs: Fair- and good-quality studies
KQs 1, 2, 4: Randomized … , controlled trials; controlled clinical trials; observational or nonrandomized studies with a contemporaneous … control
KQ 3: Randomized, controlled trials; controlled clinical trials; large screening registry