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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Nvjr8BPsZhy4XGc7-rGjAH
June 18, 2018 - HPV
for cervical cancer screening (HPV FOCAL):
Complete round 1 results of a randomized trial
comparing … controlled trial. … Results at recruitment from a randomized
controlled trial comparing human papillomavirus
testing alone … A randomized controlled trial of human
papillomavirus (HPV) testing for cervical cancer
screening: trial … POBASCAM, a population-based randomized
controlled trial for implementation of high-risk HPV
testing
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/child-maltreatment-primary-care-interventions
May 19, 2022 - less than “very high” on the Human Development Index
Study designs
KQ 1: RCTs
KQ 2: RCTs, controlled … reviews
Editorials, commentaries, and narrative reviews
Abbreviations: KQ=key question; RCT=randomized … , controlled trial. … Randomized, controlled trials offer the highest rigor for benefits. … Observational studies have inherently higher potential risk of bias than randomized, clinical trials;
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary5/visual-impairment-in-children-ages-1-5-screening-2011
January 15, 2011 - We selected randomized trials and controlled observational studies on preschool vision screening and … No randomized trial evaluated preschool vision screening compared with no screening. … A randomized controlled trial of unilateral strabismic and mixed amblyopia using occlusion dose monitors … A randomized trial of patching regimens for treatment of moderate amblyopia in children. … The emotional impact of amblyopia treatment in preschool children: randomized controlled trial.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/KbJjfcaP9XvhkP43u-7b9q
July 01, 2014 - A randomized, controlled trial of a 24-month course of interferon alfa 2b
in patients with chronic hepatitis … A randomized, controlled trial of interferon alfa-2b alone and after pred-
nisone withdrawal for the … controlled trial. … controlled
trial. … Randomized controlled trial of screening
for hepatocellular carcinoma.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/vision-screening-children-ages-6-months-5-years
July 24, 2025 - Studies only providing associations, correlations, or other outcomes
Study designs
KQ 1: Randomized … , controlled trials and prospective cohort studies with an eligible comparator
KQ 2: Cross-sectional … studies, cohort studies, or trials focused on assessment of diagnostic accuracy
KQs 3, 5: Randomized … , controlled trials; controlled cohort studies; case-control studies
KQ 4: Randomized, controlled
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/REES__d2DxtDLhZCXQjpPW
July 01, 2007 - For other groups, both randomized, con-
trolled studies and nonrandomized, prospective, controlled studies … , controlled trials and nonran-
domized, prospective, controlled studies. … Women at Increased Risk
In 2001, on the basis of a good-quality randomized,
controlled trial by Scholes … In a cluster randomized
trial, Ostergaard and colleagues (12) found that a 1-time,
home-based screening … The USPSTF thus con-
sidered this to be a trial of screening women at increased
risk and not a trial
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/breast-and-ovarian-cancer-brca-testing-screening-2005
September 15, 2005 - Of these, 9 studies met criteria for fair to good quality. 105-113 One randomized, controlled trial … Chemoprevention
Four randomized, placebo-controlled prevention trials of tamoxifen 133-136 and 1 trial … Effects of individualized breast cancer risk counseling: a randomized trial. … controlled trial. … Randomized, Controlled Trials and Cohort Studies
Criteria
Initial assembly of comparable groups
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prostate-cancer-screening-adults
December 21, 2023 - , controlled trials
KQ 1: Cohort studies with concurrent control group and adjustment for confounders … , controlled trials. … ¶ Sample size of at least 1,000; uncontrolled studies only eligible if randomized, controlled trials … Mortality results from a randomized prostate-cancer screening trial. … Screening and prostate-cancer mortality in a randomized European study.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/2XRG8Dz2EegVWYUrRThgmD
October 01, 2015 - , controlled trial; SR = sustained release. … Alternative
smoking cessation aids: a meta-analysis of randomized controlled
trials. … Nicotine gum for pregnant smokers: a randomized con-
trolled trial. … Nicotine
patches for pregnant smokers: a randomized controlled study. … Randomized, controlled pilot trial of bupropion for
pregnant smokers: challenges and future directions
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/thMRXgCVQmNUsYo6dmXEc3
May 01, 2004 - controlled trial in the United Kingdom, the Avon
Longitudinal Study of Pregnancy and Childhood
(ALSPAC … controlled trials, 1999–2003, for the U.S. … Screening for amblyopia in preschool children:
results of a population-based, randomized controlled
trial … Randomised
controlled trial of treatment of unilateral visual
impairment detected at preschool vision … A
randomized trial of atropine versus patching for
treatment of moderate amblyopia in children.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/uM5P-6XpsqVfEC2axGnZaD
November 16, 2020 - Intervention study for
smoking cessation in diabetic patients:
a randomized controlled trial in both … controlled
trial. … a randomized controlled trial. … Baby BEEP: a randomized
controlled trial of nurses’ individualized social
support for poor rural pregnant … A randomized trial of e-cigarettes versus
nicotine-replacement therapy.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/carotid-artery-stenosis-screening
November 14, 2019 - nerve injuries)
KQs 1, 2: Diagnostic accuracy; CVD risk prediction
Study designs
KQs 1–3: Randomized … , controlled trials
KQ 4: Randomized, controlled trials; large cohort studies or registries … All KQs: Cost-effectiveness analyses
KQs 1–3: All study designs other than randomized, controlled
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-nonpregnant-adolescents-and-adults1/human-immunodeficiency-virus-hiv-infection-screening
June 11, 2019 - Data Sources: Ovid MEDLINE, the Cochrane Central Register of Controlled Trials, and the Cochrane Database … Study Selection: Nonpregnant individuals 12 years and older; randomized clinical trials (RCTs) and controlled … Data Sources and Searches
Ovid MEDLINE, the Cochrane Central Register of Controlled Trials, and the … trial. … trial.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/cardiovascular-disease-screening-using-nontraditional-risk-assessment
September 03, 2015 - English language only
Study quality
Fair or good quality only
Abbreviations: CCT = controlled … clinical trial; CVD = cardiovascular disease; RCT = randomized, controlled trial.
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan17/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd-august-2014
May 15, 2013 - pressure >90 mm Hg, low-density lipoprotein cholesterol >160 mg/dL, or total cholesterol >200 mg/dL; or trial … supervised exercise with the goal of assessing effects of exercise)
Interventions providing controlled … Less than 6 months or 60% followup
Study Designs
KQs 1–3: Systematic reviews, randomized … controlled trials, controlled clinical trials (prior to 2001: randomized controlled trials only) … KQ 4: Systematic reviews, randomized controlled trials, controlled clinical trials, comparative cohorts
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6fMLEz4CfAVoj9YBYVbm73
April 17, 2018 - trial. … HRT and Vit D in prevention of non-vertebral
fractures in postmenopausal women; a 5 year
randomized trial … Vitamin D supplementation and
fracture incidence in elderly persons: a randomized,
placebo-controlled … Randomized
controlled trial of calcium supplementation in
healthy, nonosteoporotic, older men. … Annual high-dose oral vitamin D and falls and
fractures in older women: a randomized controlled
trial
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/o7FfN6a6DA5LqDsfMgBxkk
June 01, 2003 - An
earlier randomized trial demonstrated that sunscreen
233
Counseling to Prevent Skin Cancer: … A randomized trial of a
community-based intervention involving 10 towns
in New Hampshire suggests that … For example, a randomized trial with young
adults found that those who used sunscreen with a
high sun … Persistent increase in children’s
sun protection in a randomized controlled
community trial. … Sunscreen use and
duration of sun exposure: a double-blind, randomized
trial.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/CW23r2jqogvTG2_-kBjRxH
January 01, 2007 - controlled trial. … controlled trial. … Randomized, double-blind, placebo-controlled, two-
period crossover clinical trial of psyllium fiber … controlled trial. … Randomized, double-blind, placebo-controlled, two-period crossover clinical trial of psyllium fiber in
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan-nonpregnant-adolescents-and-adults/human-immunodeficiency-virus-hiv-infection-screening
June 15, 2017 - Initiation of antiretroviral therapy at higher vs. lower CD4 counts
Study designs
KQs 1–3: Randomized … , controlled trials and controlled observational studies
KQ 4: Randomized, controlled trials and … large controlled observational studies
KQ 5: Randomized, controlled trials and controlled observational
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www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/healthy-diet-and-physical-activity-counseling-adults-with-high-risk-of-cvd
September 13, 2018 - dyslipidemia, metabolic syndrome, or 10-year CVD risk ≥7.5% based on a CVD risk assessment tool, or trial … incentives or supervised exercise, with the goal of assessing effects of exercise)
Interventions providing controlled … postbaseline
<6 months postbaseline
Study designs
Fair- to good-quality studies
KQs 1–3: Randomized … , controlled trials; controlled clinical trials (prior to 2001, randomized, controlled trials only) … KQ 4: Systematic reviews; randomized, controlled trials; controlled clinical trials; comparative cohorts