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effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
January 01, 2011 - Variables that are potentially on the
pathway from treatment to outcome are not
controlled for, as … data are
described in detail in a number of textbooks.12-13
For matched study designs (e.g., case-controlled … assess the balance in study covariates achieved by
matchingin a similar manner to the comparison of
randomized … treatment groups from a randomzed
clinical trial.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_surveillance.pdf
December 01, 2012 - filters were not applied to any of the searches although the Cochrane Central
Register only contains randomized … or controlled clinical trials. … venous thrombosis; VTE: venous
thromboembolism; PE= pulmonary embolism; OR= pulmonary embolism; RCT=Randomized … Abbreviations: RCT=randomized controlled trial; pts=patients; yr(s)=years; NR=not reported; vs.= versus … CER=comparative effectiveness review; RCT=randomized controlled trial; pts=patients; yr(s)=years; NR=
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children_research-protocol.pdf
June 04, 2010 - controlled trials (RCT). … We will also search online trial registries (e.g., World
Health Organization, ClinicalTrials.gov, ISRCTN … be conducted to assess the robustness of the findings
across study quality, parallel vs. crossover trial … Quinolones/to, po, ct, ad, tu, ae
75. or/40-41,58-74
76. or/57,75
77. and/39,76
78. randomized controlled … trial.pt.
79. controlled clinical trial.pt.
80. randomi?
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effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
June 01, 2015 - The experts
also called for randomized controlled trials to compare secukinumab and existing therapies … placebo-controlled trial with
intravenous loading and subcutaneous
maintenance dosing. … ,
placebo-controlled trial with subcutaneous
loading and maintenance dosing. … 17a-significantly-improves-signs-and-symptoms-of-active-ankylosing-spondylitis-results-of-a-52-week-phase-3-randomized-placebo-controlled-trial-with … 17a-significantly-improves-signs-and-symptoms-of-active-ankylosing-spondylitis-results-of-a-phase-3-randomized-placebo-controlled-trial-with-subcu
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/migraine-emergency_disposition-comments.pdf
November 27, 2012 - I am curious why cohort
studies and non-randomized trials were included. … triptan section there does not seem to be reference to the
sumatriptan – Cafergot (European Cafergot trial … Acute
migraine treatmment with droperidol: A randomized, double-blind,
placebo-controlled trial. … We used the data from the placebo controlled
trials in our network meta-analysis. … controlled trials.—
Change the word authors to investigators.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse_disposition-comments.pdf
July 10, 2012 - controlled trials, mainly provide population
level information to help determine whether
we should … These included
randomised controlled trials and other studies adopting
experimental design. … A multi-country controlled trial of
strategies to promote dissemination and implementation of brief … We were unable to identify
any double-blind randomized controlled trials
of pharmacotherapy that identified … It now states: “We were unable to
identify any double-blind randomized
controlled trials of pharmacotherapy
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-pregnancy-postpartum_executive.pdf
July 01, 2014 - Top-tier evidence included randomized controlled trials
(RCTs) and systematic reviews comparing pregnant … Direct evidence was limited to one small
placebo-controlled trial that we rated as high risk of bias … Although these results controlled for
depression, the comparison groups were children of women
who … trial. … A randomized
controlled trial of internet-based therapy in depression.
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effectivehealthcare.ahrq.gov/sites/default/files/introduction-user-guide-to-ocer_130129.pdf
April 26, 2012 - In addition, therapies that demonstrate
efficacy in well-controlled experimental settings like
randomized … controlled trials may perform differently
in general clinical practice, where there is a wider
diversity … As findings
from well controlled studies are published in the
health care literature, knowledge accumulates … For studies designed as randomized clinical trials,
research protocols are common and standards
have
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
January 01, 2012 - RCTs = randomized controlled trials
Challenges With Regard to the Research Question
Populations … The efficacy of a
pharmacologic intervention is often established in placebo-controlled randomized … controlled trials and
observational studies in several ways. … controlled trials (RCTs), such as observational studies or case reports. … Randomized trial of estrogen
plus progestin for secondary prevention of
coronary heart disease in
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_executive.pdf
May 01, 2013 - Study Selection
We reviewed titles followed by abstracts to identify
randomized controlled trials … Only six were randomized controlled trials. … This pilot trial randomized patients to
usual care plus IVC filters versus usual care but was
underpowered … Although we included study designs
other than randomized controlled trials in our review, the
identification … and indexing of observational studies is far
more challenging than that of randomized controlled trials
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
January 01, 2020 - The author should list the type of
study conducted (i.e. controlled trial, cohort etc). … Weinberg, 2010, is a randomized controlled trial of
Varivax vs placebo in HIV positive subjects. … Ngan, 2010, is a double blind randomized
controlled trial of healthy Chinese women
conducted in a single … Bhatla,
2010, is a double blind randomized controlled trial
of healthy Indian women conducted in 4 … Please consider adding information from the placebo-
controlled trial by Manoff of 23-valent pneumococcal
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
September 01, 2008 - Use of insulin aspart 70/30 in randomized
controlled trials was associated with a higher incidence
of … The randomized trial found that the
basal-bolus regimen was more effective than insulin
lispro 50/50 … The nonrandomized prospective trial
found that insulin aspart 70/30 was similar to the basal-
bolus regimen … In the
second parallel-arm randomized study enrolling 403
patients, all oral antidiabetic agents were … controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/nephropathy-contrast-induced_disposition-comments.pdf
January 07, 2016 - As far as I can tell, though, even though it is by far the largest
randomized clinical trial (RCT) ever … the ACT trial,
which says, “The implications of this adequately powered, well-conducted clinical trial … The meta-analysis included 63 randomized controlled trials which were
mostly small and open label. … Circulation 2011, which was a well powered (n= 2308), multicenter, randomized,
placebo controlled trial … This brings into question the results
of at least 13 randomized, controlled trials that reported NAC
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
January 01, 2012 - Of 24 studies
that compared SMBP alone versus usual care, 22 were
randomized controlled trials (RCTs … additional support or with less intense additional support, of which 11 were RCTs
and 1 was quasi-randomized … • Four trials reported subgroup analyses by control of BP at baseline (controlled
or not controlled … diastolic blood pressure; Euro QoL 5D = Euro QoL Group 5-Dimension Self Report Questionnaire; RCT =
randomized … controlled trial; SBP = systolic blood pressure; SF-12/36 = Short Form-12/36 Health Survey; SMBP = self-measured
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
June 01, 2010 - Unfortunately, the two
large, randomized controlled trials on the efficacy and safety of rFVIIa
in … Results • Unpublished studies
− The two large, randomized controlled trials on the efficacy and … Safety and efficacy of recombinant activated factor VII: a
randomized placebo-controlled trial in the … , Placebo-
controlled trial. … Results from an open-label, randomized, multicenter trial.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
September 11, 2015 - controlled trials (RCTs), nonrandomized controlled trials
(non-RCTs), prospective cohort studies, … and controlled
before-after studies. … trial. … trial. … Meta-analysis
of randomized educational and behavioral interventions
in type 2 diabetes.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
January 01, 2012 - Goudie, et al. assessed a
sample of randomized controlled trials (RCTs) published in leading medical … Indeed, some
commentators have proposed a moratorium on new efficacy randomized controlled trials to … controlled trials. … controlled trial
SR Systematic review
VOI Value of information
A-1
Appendix A. … Study design NA
Randomized controlled trials.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
April 01, 2015 - In randomized controlled clinical trials, continuous outcomes are typically
measured at both baseline … Assessing the impact of attrition in
randomized controlled trials. … Quantifying bias in randomized controlled
trials in child health: a meta-epidemiological
study. … Understanding
controlled trials: baseline imbalance in
randomised controlled trials. … controlled clinical trial
REML restricted maximum likelihood
SMD standardized mean difference
TMS
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
April 01, 2013 - Findings of CER
The CER synthesized data from eligible randomized controlled trials (RCTs) for efficacy … controlled trials. … controlled trials. … controlled trials. … For example, factors that affect the feasibility of conducting
randomized controlled trials include
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
January 01, 2010 - We found one systematic review of randomized controlled trials
(RCTs) published in 2007 that compared … We will include both randomized controlled trials and observational studies that evaluate
microvascular … For all other outcomes, we will
include only randomized controlled trials. … clinical trial. … HbA1c = hemoglobin A1c
MDI = multiple daily injections
RCT = randomized controlled trial
rt-CGM