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Total Results: 1,524 records

Showing results for "randomized controlled trial".

961. Infectious Disease Including HIV/AIDS #09 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/infectiousdisease_hi_impact.pdf
     December 01, 2013 - controlled trials with identical protocols comparing oral fidaxomicin (200 mg twice daily) to oral … controlled trials (RCT) with 1105 patients. … Randomized controlled trial (RCT) of fidaxomicin (FDX) versus vancomycin (VAN) in treatment of recurrent … Fidaxomicin shows early superiority over vancomycin on intention-to-treat analyses of pivotal randomized … controlled trials in clostridium difficile infection [abstract].

962. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-update_research-protocol.pdf
     May 07, 2010 - with treatment protocols that permitted the addition of other antihypertensive medications during the trial … We will search MEDLINE® (May 2006 to present) and the Cochrane Central Register of Controlled Trials … We will include English-language reports of controlled trials or cohort studies that compared an angiotensin … Comparators of interest, Outcomes, Timing, and Settings PVD Peripheral vascular disease RCT Randomized … control trial TC Total cholesterol TEP Technical Expert Panel TG Triglyceride VII.

963. Colorectal-Cancer-Protocol_130520 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-cancer-staging_research-protocol.pdf
     May 20, 2013 - For questions about test performance, studies of any design—randomized, cross-sectional, case-control … The trial will be rated as having moderate risk of bias if it does not meet the criteria for either … The trial will be rated as having high risk of bias if all five of the critical questions are answered … The trial will be rated as Moderate risk of bias if it does not meet the criteria for either Low or … ECRI Instrument for controlled/comparative studies 1.

964. Association Between Outcomes and Dental Services in People Receiving Treatment for Human Immunodeficiency Virus: A Rapid Response Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-immunodeficiency-virus-rapid-response.pdf
     May 01, 2025 - - Study Design ● Systematic reviews with or without meta- analyses ● Randomized controlled trials … ROBINS-I gave non-randomized controlled interventional studies a score of low, moderate, serious, or … controlled trial RoB Risk of bias RR Relative risk SD Standard deviation SME Subject matter expert … s OR comparat$3 OR stud$3 OR trial$1)) OR ((control$5 OR epidemiologic$2 OR evaluat$4 OR exploratory … controlled clinical trial http://dx.doi.org/10.1016 /j.pdpdt.2019.101608 Outcomes not of interest

965. S103 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s103.pdf
     October 01, 2007 - For example, in a study of 2 treatments that are randomly assigned—as in a randomized controlled trial—the … Randomized controlled trials have demonstrated that 3 �-blockers improve survival in individuals with … Although randomized controlled trials have shown several older �-blockers to have a survival benefit … these patients should be switched to newer (and likely more expensive) �-blockers that have clinical trial … controlled trials.

966. Towards a Framework for Communicating Confidence in Methodological Recommendations for Systematic Reviews and Meta-Analyses (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
     September 01, 2013 - trial, but not in general –see reference 31, Robins JM, Scheines R, Spirtes P, et al. … Identification of randomized controlled trials in systematic reviews: accuracy and reliability of screening … controlled trial. … A randomized trial. … Effect of blinding and unmasking on the quality of peer review: a randomized trial.

967. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/01_arthritis_potential_high_impact_2012-12-10.pdf
     January 01, 2012 - The evidence base for PRP lacks sufficiently large, blinded, prospective, randomized controlled trials … controlled trials to determine whether the procedure regenerates cartilage, has a durable effect … However, some of the experts stated that large, randomized, double-blind trials are needed to better … Experts stated that PRP injections could gain broader acceptance if shown to be effective in randomized … Placebo-controlled trial of tofacitinib monotherapy in rheumatoid arthritis.

968. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
     June 06, 2011 - Controlled Trials, Clinical Trial Results, WHO Trial Registries), grants databases (NIHRePORTER, HSRProj … To identify systematic reviews, we will search the Cochrane Databases of Systematic Reviews and Controlled … KQ, we will search the Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled … Methodological Quality of Individual Studies We will assess the quality of systematic reviews, randomized … Evaluating non-randomized intervention studies.

969. breast-biopsy-update-130920 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
     September 20, 2013 - Studies must have been prospective or retrospective cohort studies or randomized controlled trials. … • Randomized controlled trials, cohort studies, and cross-sectional studies on patient preferences … This search will be adapted for use in MEDLINE®, EMBASE®, the Cochrane Central Register of Controlled … Thus, randomized controlled trials will be graded as having a high, medium, or low risk of bias, and … study/ or exp clinical trial/ or exp comparative study/ or cohort analysis or follow-up studies.de.

970. Disposition of Comments for Strategies To Prevent Weight Gain Among Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_disposition-comments.pdf
     March 25, 2013 - This trial involves 500 women who were randomized to lifestyle intervention or control and tests the … , double-blind, placebo- controlled, adequately powered trials can often be performed. … Changed non-randomized to observational. … Importantly, most of these “approaches” were not tested in randomized controlled trials and thus the … The best known weight gain prevention trial was excluded for this reason, the Pound of Prevention trial

971. Disposition of Comments for CER 160 Binge Eating Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating-disposition-160504.pdf
     December 09, 2015 - , Double-Blind, Placebo-Controlled Trial. … , Double- Blind, Placebo-Controlled Trial. … , Double-Blind, Placebo-Controlled Trial. … We have added examples of questions included in the randomized controlled trial and observational study … (2011) “Allegiance Bias and Therapist Effects; Results of a Randomized Controlled Trial of Binge Eating

972. Arthritis and Nontraumatic Joint Disease (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
     June 01, 2015 - The experts also called for randomized controlled trials to compare secukinumab and existing therapies … placebo-controlled trial with intravenous loading and subcutaneous maintenance dosing. … , placebo-controlled trial with subcutaneous loading and maintenance dosing. … 17a-significantly-improves-signs-and-symptoms-of-active-ankylosing-spondylitis-results-of-a-52-week-phase-3-randomized-placebo-controlled-trial-with … 17a-significantly-improves-signs-and-symptoms-of-active-ankylosing-spondylitis-results-of-a-phase-3-randomized-placebo-controlled-trial-with-subcu

973. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
     September 01, 2008 - Use of insulin aspart 70/30 in randomized controlled trials was associated with a higher incidence of … The randomized trial found that the basal-bolus regimen was more effective than insulin lispro 50/50 … The nonrandomized prospective trial found that insulin aspart 70/30 was similar to the basal- bolus regimen … In the second parallel-arm randomized study enrolling 403 patients, all oral antidiabetic agents were … controlled trials.

974. Measuring-Blood-Pressure Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
     January 01, 2012 - Of 24 studies that compared SMBP alone versus usual care, 22 were randomized controlled trials (RCTs … additional support or with less intense additional support, of which 11 were RCTs and 1 was quasi-randomized … • Four trials reported subgroup analyses by control of BP at baseline (controlled or not controlled … diastolic blood pressure; Euro QoL 5D = Euro QoL Group 5-Dimension Self Report Questionnaire; RCT = randomized … controlled trial; SBP = systolic blood pressure; SF-12/36 = Short Form-12/36 Health Survey; SMBP = self-measured

975. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
     June 01, 2010 - Unfortunately, the two large, randomized controlled trials on the efficacy and safety of rFVIIa in … Results • Unpublished studies − The two large, randomized controlled trials on the efficacy and … Safety and efficacy of recombinant activated factor VII: a randomized placebo-controlled trial in the … , Placebo- controlled trial. … Results from an open-label, randomized, multicenter trial.

976. Behavioral Programs for Diabetes Mellitus (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
     September 11, 2015 - controlled trials (RCTs), nonrandomized controlled trials (non-RCTs), prospective cohort studies, … and controlled before-after studies. … trial. … trial. … Meta-analysis of randomized educational and behavioral interventions in type 2 diabetes.

977. Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
     January 01, 2012 - Goudie, et al. assessed a sample of randomized controlled trials (RCTs) published in leading medical … Indeed, some commentators have proposed a moratorium on new efficacy randomized controlled trials to … controlled trials. … controlled trial SR Systematic review VOI Value of information A-1 Appendix A. … Study design NA Randomized controlled trials.

978. Choice-Of-Mean White-Paper (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
     April 01, 2015 - In randomized controlled clinical trials, continuous outcomes are typically measured at both baseline … Assessing the impact of attrition in randomized controlled trials. … Quantifying bias in randomized controlled trials in child health: a meta-epidemiological study. … Understanding controlled trials: baseline imbalance in randomised controlled trials. … controlled clinical trial REML restricted maximum likelihood SMD standardized mean difference TMS

979. FRN 35 - Preventive Pharmacological Treatments for Migraine in Adults: Future Research Needs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
     April 01, 2013 - Findings of CER The CER synthesized data from eligible randomized controlled trials (RCTs) for efficacy … controlled trials. … controlled trials. … controlled trials. … For example, factors that affect the feasibility of conducting randomized controlled trials include

980. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
     January 01, 2010 - We found one systematic review of randomized controlled trials (RCTs) published in 2007 that compared … We will include both randomized controlled trials and observational studies that evaluate microvascular … For all other outcomes, we will include only randomized controlled trials. … clinical trial. … HbA1c = hemoglobin A1c MDI = multiple daily injections RCT = randomized controlled trial rt-CGM