-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
January 01, 2013 - duration as subjects were
randomized after failure to respond to the
lower dose. … A double-blind placebo-controlled trial of
lamotrigine as an antidepressant augmentation
agent in treatment-refractory … , double-blind, placebo-
controlled, efficacy trial. … Controlled Trial; SCEPC: Southern
California Evidence-based Practice Center
20
Appendix C. … duration as subjects were
randomized after failure to respond to the
lower dose.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
July 18, 2011 - trial; NSAIDs = nonsteroidal anti-inflammatory drugs; RCT =
randomized controlled trial. … This search will include trial registries
such as ClinicialTrials.gov, metaRegister of Controlled Trials … controlled trials and nonrandomized controlled trials.
20
The tool examines six
domains (sequence … controlled trials vs. nonrandomized
controlled trials) and random effects versus fixed effects analyses … All trial groups will be
considered separately in the analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/executive-summary-2017-schizophrenia-adult.pdf
January 01, 2017 - Randomized controlled trials were evaluated with criteria
developed by the Drug Effectiveness Review … Cognitive behavior therapy for
schizophrenia: a meta-analytical review of randomized controlled
trials … A randomized controlled
trial of cognitive-behavior therapy for persistent symptoms
in schizophrenia … Cognitive therapy and
recovery from acute psychosis: a controlled trial. 3. Five-year
follow-up. … Results of a multisite
randomized trial of supported employment interventions for
individuals with
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/major-depressive-disorder_executive.pdf
December 01, 2015 - trials
– Prospective controlled cohort studies
– Retrospective controlled cohort studies
– Case-control … = complementary and alternative medicine; KQ = Key Question; MDD = major depressive disorder; RCT = randomized … controlled trial;
SGA = second-generation antidepressant; SR = systematic review
aSGAs approved for … determine risk of bias in a standardized way,
we used the Cochrane Risk of Bias tool to appraise
randomized … Second-Generation Antidepressants Versus Third-Wave
Cognitive Behavioral Therapy
Two randomized trials
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - ○ Randomized controlled trials of test-and-treat strategies
○ Nonrandomized comparative studies … Thus randomized controlled trials will be graded as having
a high, medium, or low risk of bias, and … Appropriate
methods will be used to account for crossover trial designs.
41
If performed, all meta … Various randomized designs can be used to evaluate medical
tests. … with ticagrelor versus clopidogrel for acute
coronary syndromes: a genetic substudy of the PLATO trial
-
effectivehealthcare.ahrq.gov/sites/default/files/s103.pdf
October 01, 2007 - For example, in a
study of 2 treatments that are randomly assigned—as in a
randomized controlled trial—the … Randomized controlled trials have demonstrated that 3
�-blockers improve survival in individuals with … Although randomized controlled trials have shown several
older �-blockers to have a survival benefit … these patients should be switched to newer (and likely
more expensive) �-blockers that have clinical trial … controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methodological-recommendations-framework-communications_research.pdf
September 01, 2013 - trial, but not in general –see reference 31,
Robins JM, Scheines R, Spirtes P, et al. … Identification of randomized controlled trials
in systematic reviews: accuracy and
reliability of screening … controlled trial. … A randomized trial. … Effect of blinding and unmasking on the
quality of peer review: a randomized trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management_research-protocol.pdf
June 06, 2011 - Controlled Trials, Clinical Trial Results, WHO Trial Registries),
grants databases (NIHRePORTER, HSRProj … To identify systematic
reviews, we will search the Cochrane Databases of Systematic Reviews and Controlled … KQ, we will search the Cochrane Database of Systematic
Reviews, the Cochrane Central Register of Controlled … Methodological Quality of Individual Studies
We will assess the quality of systematic reviews, randomized … Evaluating non-randomized intervention studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
September 20, 2013 - Studies must have been prospective or retrospective cohort studies or randomized controlled
trials. … • Randomized controlled trials, cohort studies, and cross-sectional studies on patient preferences … This search will be adapted
for use in MEDLINE®, EMBASE®, the Cochrane Central Register of Controlled … Thus, randomized controlled trials will be graded as having a high,
medium, or low risk of bias, and … study/ or exp clinical trial/ or exp
comparative study/ or cohort analysis or follow-up studies.de.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/weight-gain-prevention_disposition-comments.pdf
March 25, 2013 - This trial involves 500 women who
were randomized to lifestyle intervention or control and
tests the … , double-blind, placebo-
controlled, adequately powered trials can often be
performed. … Changed non-randomized to observational. … Importantly, most
of these “approaches” were not tested in randomized
controlled trials and thus the … The best known weight gain prevention trial
was excluded for this reason, the Pound of Prevention trial
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating-disposition-160504.pdf
December 09, 2015 - , Double-Blind, Placebo-Controlled Trial. … , Double-
Blind, Placebo-Controlled Trial. … , Double-Blind,
Placebo-Controlled Trial. … We have added examples of questions included in the
randomized controlled trial and observational study … (2011) “Allegiance Bias and Therapist Effects; Results of a
Randomized Controlled Trial of Binge Eating
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
June 01, 2015 - The experts
also called for randomized controlled trials to compare secukinumab and existing therapies … placebo-controlled trial with
intravenous loading and subcutaneous
maintenance dosing. … ,
placebo-controlled trial with subcutaneous
loading and maintenance dosing. … 17a-significantly-improves-signs-and-symptoms-of-active-ankylosing-spondylitis-results-of-a-52-week-phase-3-randomized-placebo-controlled-trial-with … 17a-significantly-improves-signs-and-symptoms-of-active-ankylosing-spondylitis-results-of-a-phase-3-randomized-placebo-controlled-trial-with-subcu
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-insulin_executive.pdf
September 01, 2008 - Use of insulin aspart 70/30 in randomized
controlled trials was associated with a higher incidence
of … The randomized trial found that the
basal-bolus regimen was more effective than insulin
lispro 50/50 … The nonrandomized prospective trial
found that insulin aspart 70/30 was similar to the basal-
bolus regimen … In the
second parallel-arm randomized study enrolling 403
patients, all oral antidiabetic agents were … controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/measuring-blood-pressure_executive.pdf
January 01, 2012 - Of 24 studies
that compared SMBP alone versus usual care, 22 were
randomized controlled trials (RCTs … additional support or with less intense additional support, of which 11 were RCTs
and 1 was quasi-randomized … • Four trials reported subgroup analyses by control of BP at baseline (controlled
or not controlled … diastolic blood pressure; Euro QoL 5D = Euro QoL Group 5-Dimension Self Report Questionnaire; RCT =
randomized … controlled trial; SBP = systolic blood pressure; SF-12/36 = Short Form-12/36 Health Survey; SMBP = self-measured
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
June 01, 2010 - Unfortunately, the two
large, randomized controlled trials on the efficacy and safety of rFVIIa
in … Results • Unpublished studies
− The two large, randomized controlled trials on the efficacy and … Safety and efficacy of recombinant activated factor VII: a
randomized placebo-controlled trial in the … , Placebo-
controlled trial. … Results from an open-label, randomized, multicenter trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_executive.pdf
September 11, 2015 - controlled trials (RCTs), nonrandomized controlled trials
(non-RCTs), prospective cohort studies, … and controlled
before-after studies. … trial. … trial. … Meta-analysis
of randomized educational and behavioral interventions
in type 2 diabetes.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
January 01, 2012 - Goudie, et al. assessed a
sample of randomized controlled trials (RCTs) published in leading medical … Indeed, some
commentators have proposed a moratorium on new efficacy randomized controlled trials to … controlled trials. … controlled trial
SR Systematic review
VOI Value of information
A-1
Appendix A. … Study design NA
Randomized controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/choice-of-mean_white-paper.pdf
April 01, 2015 - In randomized controlled clinical trials, continuous outcomes are typically
measured at both baseline … Assessing the impact of attrition in
randomized controlled trials. … Quantifying bias in randomized controlled
trials in child health: a meta-epidemiological
study. … Understanding
controlled trials: baseline imbalance in
randomised controlled trials. … controlled clinical trial
REML restricted maximum likelihood
SMD standardized mean difference
TMS
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-future_research.pdf
April 01, 2013 - Findings of CER
The CER synthesized data from eligible randomized controlled trials (RCTs) for efficacy … controlled trials. … controlled trials. … controlled trials. … For example, factors that affect the feasibility of conducting
randomized controlled trials include
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
January 01, 2010 - We found one systematic review of randomized controlled trials
(RCTs) published in 2007 that compared … We will include both randomized controlled trials and observational studies that evaluate
microvascular … For all other outcomes, we will
include only randomized controlled trials. … clinical trial. … HbA1c = hemoglobin A1c
MDI = multiple daily injections
RCT = randomized controlled trial
rt-CGM