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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f-surv-report-3-acute-pain.xlsx
May 29, 2025 - Risk of bias assessment for randomized controlled trials
Author, Year
(Full Citations Are Listed in … No Yes; 11% Yes Poor
Ilyas, 2021 No (by birth year) No Yes Yes No No Yes No/No No Yes; excluded 44 randomized
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-f-surv-report-2-acute-pain.xlsx
May 29, 2025 - Risk of bias assessment for randomized controlled trials
Author, Year
(Full Citations Are Listed in … No Yes; 11% Yes Poor
Ilyas, 2021 No (by birth year) No Yes Yes No No Yes No/No No Yes; excluded 44 randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-5.pdf
February 01, 2018 - can be used to compare one
intervention to another, when they have not been analyzed in the
same trial … that they were equally
likely to received any of the treatments in the network.
• Active and placebo controlled … The results of direct and indirect treatment comparisons in
meta-analysis of randomized controlled trials … Evaluation of networks of randomized trials. Stat Methods Med Res. 2008;17(3):279-301. … The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/fiber-intake-protocol.pdf
August 15, 2023 - controlled trials
o Parallel or cross-over
• N ≥10/group
• Observational studies
• All other study … e.g., wide
range of fiber content in whole wheat bread), the review restricts the Study Design to
randomized … controlled trials that explicitly control and state the amount of fiber intake. … Search strategies will include filters to restrict to randomized controlled trials and
systematic reviews … The only eligible study design is randomized controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - clinical trial. … AHRQ Report Reference: AHRQ Report Page 87: “One
randomized trial reported data on dizziness when levetiracetam … We have made the following change:
One randomized controlled trial reported data on
dizziness when … AHRQ Report Page 84: "One randomized controlled trial
reported data on somnolence while patients were … AHRQ Report Page 84: “One randomized controlled trial
reported data on nausea while patients were receiving
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/engaging-caregivers-appendix-c.xlsx
May 29, 2025 - Risk of bias for randomized controlled trials
Author, Year Randomization Adequate?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
February 01, 2012 - For the assessment of study designs, EPC staff evaluated the appropriateness
of a randomized trial, … Resource use would be
similar to randomized trial. … , Editorial, Practice Guideline, Randomized
Controlled Trial, Case Reports, Comparative Study, Controlled … , Editorial, Practice Guideline, Randomized Controlled Trial, Case Reports, Comparative
Study, Controlled … , Editorial, Practice Guideline, Randomized
Controlled Trial, Case Reports, Comparative Study, Controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/future05-breastcancer-10-5-2010final.pdf
September 01, 2010 - Controlled
Trials, Clinical Trial Results, WHO Trial Registries) and grant databases (NIHRePORTER, … studies,
reviews)
185, 194, 195
SERMs (focus of
original CER)e
Randomized controlled trials … controlled trials I
Observational studies 223
Gene-based drugs Randomized controlled trials … +
diet; medications +
aspirin
Randomized controlled trials 52, 63, 226,
227
192, 228, 229 210 … controlled trial in osteoporotic
postmenopausal women.
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - TEP 1 Results Clinical trial should be clearly defined as "randomized
trials" because many consider … We
included both randomized and nonrandomized
trials; our added definition of a nonrandomized
trial … will help clarify this and differentiate them
from controlled observational studies. … contrary to the fact that observational studies, by
definition, are subject to more biases than
randomized … We are happy our interpretations were correct
for the controlled phase.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - TEP 1 Results Clinical trial should be clearly defined as "randomized
trials" because many consider … We
included both randomized and nonrandomized
trials; our added definition of a nonrandomized
trial … will help clarify this and differentiate them
from controlled observational studies. … contrary to the fact that observational studies, by
definition, are subject to more biases than
randomized … We are happy our interpretations were correct
for the controlled phase.
-
effectivehealthcare.ahrq.gov/sites/default/files/peptic-ulcer-horizon-scan-high-impact-1306.pdf
June 01, 2013 - In the absence of
randomized controlled trials or long-term outcomes data, some experts were uncertain … controlled trials. … , double-blind, placebo-controlled, phase III trial,
investigators reported that 63% of patients (n … , double-blind, placebo-controlled, trial comparing teduglutide with
placebo was conducted. … , placebo-controlled, clinical
trials and two extension studies.36
Diffusion: A query of a U.S.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
February 01, 2012 - Randomized Controlled Trials (RCTs)
A randomized comparison of screening for OSA with extended anesthesia … Effectiveness or efficacy of
treatments can be most definitively addressed in randomized controlled … Randomized Controlled Trials
Value of Study Design
The CER found no trials of preoperative screening … controlled trial (RCT). … controlled trial
A-1
Appendix A.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
January 10, 2012 - A recent update of a Cochrane
Collaboration review
13
found only one randomized clinical trial
14 … A systematic review published in 2006 found that 51 of 59 included randomized controlled
trials assessed … or comparative randomized and nonrandomized trials and controlled or
comparative observational studies … • KQ 2: studies of predictive validity
• KQ 3: controlled or comparative randomized and nonrandomized … trials and controlled or
comparative observational studies
• KQ 4: randomized trials, cohort studies
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
August 16, 2016 - Of greatest importance is that the
update includes data from 3 randomized controlled trials
(RCT’s … and non-randomized comparative studies. … We have added that the STAR trial was the
only trial to explicitly include patients with
CHF (~10%) … controlled clinical trials, rather
than the results themselves, is refreshing and of crucial
importance … clinical trials - those with a moderate degree of stenosis,
blood pressure that can be controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
January 01, 2007 - An analysis of a previously reported randomized trial that compared immediate
angioplasty and either … While evidence
from high quality randomized controlled trials (RCTs) was preferred, these data were … Among the RCTs of
angioplasty versus medical therapy, only the SNRASCG randomized trial (Webster 1998 … A meta-analysis of randomized
controlled trials. Am J Med. 2003;114:44-50.
26. … controlled trial
RI Resistive index
SBP Systolic blood pressure
SCr Serum creatinine
SNRASCG
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - ○ Randomized controlled trials of test-and-treat strategies
○ Nonrandomized comparative studies … Thus randomized controlled trials will be graded as having
a high, medium, or low risk of bias, and … Appropriate
methods will be used to account for crossover trial designs.
41
If performed, all meta … Various randomized designs can be used to evaluate medical
tests. … with ticagrelor versus clopidogrel for acute
coronary syndromes: a genetic substudy of the PLATO trial
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-quality.ppt
January 01, 2010 - quality of an individual study, the first step is to evaluate the study design and classify studies as randomized … Predefined Criteria for All Study Types (I)
Commonly used tools can be found in the following publications:
Randomized … controlled trials quality rating tools
West S, King V, Carey TS, et al. … Collaborative Group and the European Carotid Surgery Trial Collaborative Group. … Collaborative Group and the European Carotid Surgery Trial Collaborative Group.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - Trials (CENTRAL) to identify previous systematic
reviews, randomized controlled trials, and prospective … Relevant grey literature resources include trial registries and FDA
databases. … controlled trials as topic/
34 randomized controlled trial/
35 random allocation/
36 double blind … method/
37 single
blind method/
38 clinical trial/
39 clinical trial, phase i.pt.
40 clinical … trial, phase ii.pt.
41 clinical trial,
phase iii.pt.
42 clinical trial, phase iv.pt.
43 controlled
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effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - epidemiologic methods, propensity score
calibration, research design
(Med Care 2007;45: S158–S165)
Randomized … controlled trials are often regarded as the most
accurate method to assess treatment effects. … trials who are healthier and
want to pursue a more healthful life style, the long time
required from trial … erroneous because effect sizes, base-
line risks, and comorbidity have been shown to differ be-
tween trial … Principal results from the Women’s Health Initiative randomized con-
trolled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
December 27, 2016 - Category Inclusion Criteria Exclusion Criteria
Setting All settings will be included None
Study Design Randomized-controlled … If data cannot
be abstracted after the first period, the trial will be included based on the following … Efficacy and safety
of budesonide/formoterol pressurized metered-dose inhaler: randomized controlled … trial comparing once- and twice-daily dosing in patients with asthma. … The ROBINS-I tool (Risk of Bias in
Non-randomized Studies – of Interventions), Version 7 March 2016.