-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/thromboembolism-update_research-protocol.pdf
February 17, 2016 - comparison to placebo or no
prophylaxis); however, because of rarity of postoperative PE, the body of randomized … controlled trial (RCT) evidence is not adequately powered to demonstrate the effect of
prophylaxis … Source: www.effectivehealthcare.ahrq.gov
Published online: February 17, 2016 6
Study design
• Randomized … controlled trials and indirect
comparisons across trials. … method OR single-blind method OR
random* OR ((clinical OR controlled) and trial*) OR ((singl* or doubl
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - TEP 1 Results Clinical trial should be clearly defined as "randomized
trials" because many consider … We
included both randomized and nonrandomized
trials; our added definition of a nonrandomized
trial … will help clarify this and differentiate them
from controlled observational studies. … contrary to the fact that observational studies, by
definition, are subject to more biases than
randomized … We are happy our interpretations were correct
for the controlled phase.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - TEP 1 Results Clinical trial should be clearly defined as "randomized
trials" because many consider … We
included both randomized and nonrandomized
trials; our added definition of a nonrandomized
trial … will help clarify this and differentiate them
from controlled observational studies. … contrary to the fact that observational studies, by
definition, are subject to more biases than
randomized … We are happy our interpretations were correct
for the controlled phase.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
January 01, 2019 - controlled
trial suggested there was no difference in treatment failure between admission and outpatient … For randomized controlled trials, we will adapt the Cochrane Risk of Bias tool,49 focusing on
issues … Randomized clinical trial of antibiotics in acute
uncomplicated diverticulitis. … Mesalazine for People with Diverticular Disease: A
Systematic Review of Randomized Controlled Trials … KQ Key Question
NRCS nonrandomized comparative study
RCT randomized controlled trial
SoE strength
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stem-cell-children-future_research.pdf
February 01, 2012 - For the assessment of study designs, EPC staff evaluated the appropriateness
of a randomized trial, … Resource use would be
similar to randomized trial. … , Editorial, Practice Guideline, Randomized
Controlled Trial, Case Reports, Comparative Study, Controlled … , Editorial, Practice Guideline, Randomized Controlled Trial, Case Reports, Comparative
Study, Controlled … , Editorial, Practice Guideline, Randomized
Controlled Trial, Case Reports, Comparative Study, Controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement_research.pdf
September 01, 2011 - Placebo
Placebo-
Controlled
Trial—
Raloxifene vs. … Placebo
Placebo-
Controlled
Trial—
Tibolone vs. … Placebo
Placebo-
Controlled
Trial—
Raloxifene vs. … Placebo
Placebo-
Controlled
Trial—
Tibolone vs. … • What can we learn from evidence that falls short of a randomized controlled trial?
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_disposition-comments.pdf
March 01, 2012 - clinical trial. … AHRQ Report Reference: AHRQ Report Page 87: “One
randomized trial reported data on dizziness when levetiracetam … We have made the following change:
One randomized controlled trial reported data on
dizziness when … AHRQ Report Page 84: "One randomized controlled trial
reported data on somnolence while patients were … AHRQ Report Page 84: “One randomized controlled trial
reported data on nausea while patients were receiving
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-quality.ppt
January 01, 2010 - quality of an individual study, the first step is to evaluate the study design and classify studies as randomized … Predefined Criteria for All Study Types (I)
Commonly used tools can be found in the following publications:
Randomized … controlled trials quality rating tools
West S, King V, Carey TS, et al. … Collaborative Group and the European Carotid Surgery Trial Collaborative Group. … Collaborative Group and the European Carotid Surgery Trial Collaborative Group.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
January 10, 2012 - A recent update of a Cochrane
Collaboration review
13
found only one randomized clinical trial
14 … A systematic review published in 2006 found that 51 of 59 included randomized controlled
trials assessed … or comparative randomized and nonrandomized trials and controlled or
comparative observational studies … • KQ 2: studies of predictive validity
• KQ 3: controlled or comparative randomized and nonrandomized … trials and controlled or
comparative observational studies
• KQ 4: randomized trials, cohort studies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-pharmacologic-treatment_research-protocol.pdf
December 27, 2016 - Category Inclusion Criteria Exclusion Criteria
Setting All settings will be included None
Study Design Randomized-controlled … If data cannot
be abstracted after the first period, the trial will be included based on the following … Efficacy and safety
of budesonide/formoterol pressurized metered-dose inhaler: randomized controlled … trial comparing once- and twice-daily dosing in patients with asthma. … The ROBINS-I tool (Risk of Bias in
Non-randomized Studies – of Interventions), Version 7 March 2016.
-
effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - epidemiologic methods, propensity score
calibration, research design
(Med Care 2007;45: S158–S165)
Randomized … controlled trials are often regarded as the most
accurate method to assess treatment effects. … trials who are healthier and
want to pursue a more healthful life style, the long time
required from trial … erroneous because effect sizes, base-
line risks, and comorbidity have been shown to differ be-
tween trial … Principal results from the Women’s Health Initiative randomized con-
trolled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tech-brief-31-mobile-applications-self-mgmt.pdf
May 01, 2018 - controlled trial. … controlled trial. … WellDoc
mobile diabetes management randomized
controlled trial: change in clinical and behavioral … controlled trial. … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-2007_executive.pdf
January 01, 2007 - Of these, 89 were head-to-head randomized
controlled trials (RCTs) and 57 were placebo-controlled
RCTs … Evidence from six head-to-head trials and one
placebo-controlled trial (all fair quality) suggests that … Step
2 and Step 3 treatments were randomly assigned using
an equipoise stratified randomized design. … In this,
1,439 patients were randomized in Step 2, which
included seven possible treatment alternatives … Step 4 used only a single
randomization; 123 patients were randomized to
tranylcypromine or venlafaxine
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-radiation_technical-brief.pdf
November 01, 2009 - controlled trial [RCT] and nonrandomized
comparative study), type of cancer, patient eligibility criteria … controlled trial
Figure 6 shows histograms of study sample sizes per cancer category. … controlled trial [see
comment]. … A
randomized controlled trial of varying
radiation doses in the treatment of choroidal
melanoma. … A
prospective, randomized, dynamically
balanced trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-update_disposition-comments.pdf
August 16, 2016 - Of greatest importance is that the
update includes data from 3 randomized controlled trials
(RCT’s … and non-randomized comparative studies. … We have added that the STAR trial was the
only trial to explicitly include patients with
CHF (~10%) … controlled clinical trials, rather
than the results themselves, is refreshing and of crucial
importance … clinical trials - those with a moderate degree of stenosis,
blood pressure that can be controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/bipolar-disorder-treatment_research-protocol.pdf
June 23, 2014 - Trials (CENTRAL) to identify previous systematic
reviews, randomized controlled trials, and prospective … Relevant grey literature resources include trial registries and FDA
databases. … controlled trials as topic/
34 randomized controlled trial/
35 random allocation/
36 double blind … method/
37 single
blind method/
38 clinical trial/
39 clinical trial, phase i.pt.
40 clinical … trial, phase ii.pt.
41 clinical trial,
phase iii.pt.
42 clinical trial, phase iv.pt.
43 controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0710-140625.pdf
January 08, 2014 - .
§ A scan of the available literature identified a number relevant randomized controlled trials … (RCTs),
controlled clinical trials (CCTs), and other studies primarily focused on different techniques
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-safety-practices-rapid-protocol.pdf
September 09, 2022 - 7,
include any study with original
quantitative or qualitative data
• For Question 5, include
randomized … controlled trials,
non-randomized controlled
trials, and observational studies
with a comparison … the primary reviewer will
assess the risk of bias using Cochrane’s Risk of Bias 2 (ROB 2) tool3 for randomized … controlled
trials (focusing on the randomization process, deviations from intended interventions, … Studies of Interventions (ROBINS-I) tool for non-randomized studies (focusing on
biases due
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/renal-artery-stenosis_research-2007.pdf
January 01, 2007 - An analysis of a previously reported randomized trial that compared immediate
angioplasty and either … While evidence
from high quality randomized controlled trials (RCTs) was preferred, these data were … Among the RCTs of
angioplasty versus medical therapy, only the SNRASCG randomized trial (Webster 1998 … A meta-analysis of randomized
controlled trials. Am J Med. 2003;114:44-50.
26. … controlled trial
RI Resistive index
SBP Systolic blood pressure
SCr Serum creatinine
SNRASCG
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
February 01, 2012 - Randomized Controlled Trials (RCTs)
A randomized comparison of screening for OSA with extended anesthesia … Effectiveness or efficacy of
treatments can be most definitively addressed in randomized controlled … Randomized Controlled Trials
Value of Study Design
The CER found no trials of preoperative screening … controlled trial (RCT). … controlled trial
A-1
Appendix A.