-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - controlled trial; Some publications reported data from the same study. … RCT=Randomized Control Trial; NRCS=Nonrandomized Comparative Trial; CI=Confidence Interval
The forest … Network of treatment comparisons (RCTs)
RCT= Randomized Control Trial; PO=Oral The network plot consists … clinical trial. … Water
precautions and tympanostomy tubes: a randomized, controlled
trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
July 01, 2009 - For these outcomes, if randomized trial data are available, EPCs may choose to start with a rating
of … EPC, Evidence-based Practice Center; RCT, randomized controlled trial.
14
Table 2. … controlled trial; SOE, strength of evidence. … Required domains and their definitions
EPC, Evidence-based Practice Center; RCT, randomized controlled … trial.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-appendix-table-b-1-version-1.xlsx
April 09, 2020 - Randomized controlled trials of mask use
Author
Registry # Publication Year Title Date Retrieved Source … trial April 9 2020 PloS One. 2010;5(11):e13998. … /744899/facemasks-hand-hygiene-prevent-influenza-transmission-households-cluster-randomized-trial Cluster … trial April 9 2020 JAMA. 2009;302(17):1865-71. … controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand
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effectivehealthcare.ahrq.gov/sites/default/files/masks-surveillance-2-appendix-table-a-1.xlsx
April 09, 2020 - Randomized controlled trials of mask use
Author
Registry # Publication Year Title Date Retrieved Source … trial April 9 2020 PloS One. 2010;5(11):e13998. … /744899/facemasks-hand-hygiene-prevent-influenza-transmission-households-cluster-randomized-trial Cluster … trial April 9 2020 JAMA. 2009;302(17):1865-71. … controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand
-
effectivehealthcare.ahrq.gov/sites/default/files/masks-appendix-table-b-1-version-2.xlsx
April 09, 2020 - Randomized controlled trials of mask use
Author
Registry # Publication Year Title Date Retrieved Source … trial April 9 2020 PloS One. 2010;5(11):e13998. … /744899/facemasks-hand-hygiene-prevent-influenza-transmission-households-cluster-randomized-trial Cluster … trial April 9 2020 JAMA. 2009;302(17):1865-71. … controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand
-
effectivehealthcare.ahrq.gov/sites/default/files/Masks-appendix-table-b-1-surveillance-report.xlsx
April 09, 2020 - Randomized controlled trials of mask use
Author
Registry # Publication Year Title Date Retrieved Source … trial April 9 2020 PloS One. 2010;5(11):e13998. … /744899/facemasks-hand-hygiene-prevent-influenza-transmission-households-cluster-randomized-trial Cluster … trial April 9 2020 JAMA. 2009;302(17):1865-71. … controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
March 26, 2013 - tool for randomized controlled trials.23 For nonrandomized comparative studies and
single-group studies … Thus, randomized controlled trials will be
graded as having a high, medium, or low risk of bias, and … Single-blinded randomized trial of mechanical
bowel preparation for colon surgery with primary intraperitoneal … trial. … A generalized linear modeling framework for pairwise
and network meta-analysis of randomized controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cell-free-dna-executive-summary.pdf
May 01, 2025 - We found no
controlled studies that reported the effectiveness of screening with MCSTs, though some … This
includes the NHS-Galleri trial, a randomized trial among 140,000 persons in the United
Kingdom … larger trial of screening with
MCSTs. … trial. … Cancer
stage compared with mortality as end points
in randomized clinical trials of cancer
screening
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
January 01, 2017 - ACTH = adrenocorticotropic hormone; N = number; NSAIDs = nonsteroidal anti-inflammatory drugs; RCT = randomized … controlled trial; SOE = strength of evidence
† The known anti-inflammatory action of these agents was … controlled trial; SOE = strength of evidence;
ULT = urate-lowering therapy
Table 4: Adverse Effects … should minimize
clinical gout sequelae, the exact target level has yet to be
formally evaluated in randomized … controlled trials, and
guidelines vary in the recommended target levels.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - A scoping literature search suggests that no randomized
controlled trials have been published since … trials (randomized and
non-randomized)
• Observational studies
o Prospective and retrospective … Table 2: Criteria to assess risk of bias within included studies
Criteria Randomized
Controlled
trials … controlled trials
• Nonrandomized controlled/comparative trials
• Prospective cohort studies
• … Terbutaline pump maintenance therapy for prevention of preterm delivery: a double-blind trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-the-risk-of-bias_draft-report.pdf
June 02, 2011 - controlled trials a high grade. … Scales to assess the quality of randomized controlled
trials: a systematic review. … and non-
randomized studies). … controlled trial, or an observational
study with a clear pre-defined inception cohort
0: study … Scales to assess the quality of randomized
controlled trials: a systematic review.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01_0.pdf
May 01, 2005 - o Do not rely solely on study design label (e.g., randomized controlled trial [RCT] or
cohort, case-control … is a hypothetical randomized controlled trial of the intervention; feasibility or ethics do not play … A target
trial is a hypothetical randomized controlled trial of the intervention; feasibility or ethics … Published methodological quality of randomized
controlled trials does not reflect the actual quality … Scales to
assess the quality of randomized controlled trials:
a systematic review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-g-surv-report-1-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Quality assessments of included randomized controlled trials
Author, Year Randomization Adequate Allocation
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
July 01, 2013 - ,
double-blind, placebo-controlled multicenter phase III trial (CONQUER) that evaluated the changes … controlled trial, SCALE™ (Satiety and Clinical Adiposity-Liraglutide Evidence in Non-
diabetic and … Multicenter, placebo-controlled trial of lorcaserin
for weight management. … Randomized placebo-controlled clinical trial of
lorcaserin for weight loss in type 2 diabetes
mellitus … A one-
year randomized trial of lorcaserin for weight loss
in obese and overweight adults: the BLOSSOM
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
April 06, 2010 - controlled trials (RCTs) and
observational studies. … controlled design; a clear description of the population,
setting, interventions, and comparison groups … to the risk of development and progression
of retinopathy in the diabetes control and complications trial … Assessing the quality of reports of randomized
clinical trials: is blinding necessary? … controlled trial; TG = triglycerides
http://www.effectivehealthcare.ahrq.gov/�
Evidence-based
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ischemic-stroke-treatment_executive.pdf
January 01, 2011 - Seven of these studies have
randomized, controlled designs with projected
enrollment ranging from 20 … Six of the
seven randomized controlled trials are allowing the use
of multiple neurothrombectomy devices … It would seem reasonable to conduct
studies to answer such research gaps using a
randomized controlled … trial design, powered to show
equivalency or non-inferiority of devices. … There remains a need for
further research on the topic, including randomized
controlled trials to determine
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
May 01, 2005 - o Do not rely solely on study design label (e.g., randomized controlled trial [RCT] or
cohort, case-control … is a hypothetical randomized controlled trial of the intervention; feasibility or ethics do not play … A target
trial is a hypothetical randomized controlled trial of the intervention; feasibility or ethics … Published methodological quality of randomized
controlled trials does not reflect the actual quality … Scales to
assess the quality of randomized controlled trials:
a systematic review.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - Controlled vocabulary terms
served as the foundation of our search, complemented by
additional keyword … One unique
indication, asymptomatic short cervix, had a randomized
trial of progesterone vaginal gel … The largest trial, which
used vaginal gel, found no evidence of effectiveness. … , double-blind, placebo-controlled trial. … trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
January 01, 2011 - experimental or
quasi-experimental designs, such as interrupted time
series,1 designed delays,2 cluster randomized … trials,
individually randomized trials, pragmatic trials, or
adaptive trials. … The limited generalizability of
findings from randomized controlled trials (RCTs),
such as to older … A two-stage trial design for testing
treatment, self-selection and treatment preference
effects. … Why do
we need some large, simple randomized trials?
Statistics in Medicine. 1984;3:409–20.
8.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
February 01, 2012 - Randomized Controlled Trials
Any future trials of CPAP or MAD should study clinical outcomes. … Randomized Controlled Trials
In general, there is limited or no need for future randomized controlled … Randomized Controlled Trials
Value of Study Design
Only one of 89 trials studied clinical outcomes … The required total sample size (1:1 ratio in a
two-arm randomized controlled trial [RCT]) for each value … controlled trial
A-1
Appendix A.