Results

Total Results: 1,523 records

Showing results for "randomized controlled trial".

401. VU EPC DBD Protocol_AHRQ comments_revised_clean (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/disruptive-behavior-disorder_research-protocol.pdf
     January 30, 2014 - Study characteristics Ideally, randomized controlled trials will be used to assess effectiveness of … We will use the Cochrane Risk of Bias Tool72 to assess risk of bias for randomized controlled trials … controlled trial[pt] OR controlled clinical trial[pt] OR clinical trial[pt] OR clinical trial[tiab] … controlled trial[pt] OR controlled clinical trial[pt] OR clinical trial[pt] OR comparative study[pt … controlled trial[pt] OR controlled clinical trial[pt] OR clinical trial[pt] OR comparative study[pt

402. Arthritis-Knee-Physical-Therapy Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
     April 01, 2010 - Original epidemiologic studies, including randomized controlled clinical trials, nonrandomized multicenter … We will include observational studies when trial data are insufficient to estimate the benefits and … • Published nonrandomized controlled trials. • Observational studies. … clinical trial or nonrandomized uncontrolled clinical trial) or observational (cohort or case-control … Controlled Trial TEP Technical Expert Panel TOO Task Order Officer VAS Visual Analogue Scale

403. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
     September 01, 2011 - reliability, validity, and responsiveness of these instruments will facilitate interpretation of clinical trial … childhood fair-quality cross-sectional or longitudinal JIA that are commonly used in clinical nonrandomized controlled … controlled trial; RR = risk ratio. 8 Remaining Issues Despite the importance of DMARDs for the … Study designs other than randomized controlled trials (RCTs) will be important in understanding the role … Randomized discontinuation trials have helped to define the risk of flare in patients who respond to

404. Research Protocol: Diabetes Medications for Adults With Type 2 Diabetes: An Update Focused on Monotherapy and Add-On Therapy to Metformin (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
     January 01, 2015 - However, in 2013, a re- analysis of the pivotal trial substantially reduced the FDA’s concern leading … ESLD = end-stage liver disease; ESRD = end-stage renal disease; KQ = Key Question; RCT = randomized controlled … trial * Of note, some outcomes could be classified as either safety or long-term clinical outcomes … Results of a reevaluation of cardiovascular outcomes in the RECORD trial. … controlled trial SGLT-2 inhibitor = sodium-glucose co-transporter 2 inhibitor VII.

405. Template for Draft Reports (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
     February 01, 2013 - Randomized controlled trials (RCTs) are the best approach. … Randomized controlled trials (RCTs) are the best approach. … A randomized controlled trial to investigate the effects of water-based exercise to improve falls risk … , controlled trial. … Controlled Trial Other: Patient education programme NCT00988468 Manual Therapy Versus Exercise on

406. EHC Research Protocol: Management of Colonic Diverticulitis (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
     January 01, 2019 - controlled trial suggested there was no difference in treatment failure between admission and outpatient … For randomized controlled trials, we will adapt the Cochrane Risk of Bias tool,49 focusing on issues … Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. … Mesalazine for People with Diverticular Disease: A Systematic Review of Randomized Controlled Trials … KQ Key Question NRCS nonrandomized comparative study RCT randomized controlled trial SoE strength

407. Stakeholder Involvement in Improving Comparative Effectiveness Reviews: AHRQ and the Effective Health Care Program (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stakeholder-engagement_research.pdf
     September 01, 2011 - Placebo Placebo- Controlled Trial— Raloxifene vs. … Placebo Placebo- Controlled Trial— Tibolone vs. … Placebo Placebo- Controlled Trial— Raloxifene vs. … Placebo Placebo- Controlled Trial— Tibolone vs. … • What can we learn from evidence that falls short of a randomized controlled trial?

408. uterine-fibroids-protocol-160301 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
     March 01, 2016 - Randomized controlled trials are best suited to provide data for comparative effectiveness and there …  controlled  trial  (KQs  1,  2)   •   Any  (KQs  3,  4)   Other   •   Original  research  (KQs  1 … controlled trials. … We will assess reporting bias of randomized controlled trials by examining outcomes of trials as reported …  controlled  trial   SERM   Selective  estrogen  receptor  modulator   SPRM   Selective  progesterone

409. RESPONSE TO REQUEST FOR WORK ASSIGNMENT (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
     December 01, 2009 - Sixth, we controlled for baseline cardiovascular medication use in regression models. … This was a four year, multinational, randomized controlled trial that compared tiotropium to placebo … The strength of the present study is that, compared with a randomized trial, we evaluated effects of … External validity of randomized controlled trials in COPD. … trial.

410. GRADING THE STRENGTH OF A BODY OF EVIDENCE (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-strength_methods.pdf
     July 01, 2009 - For these outcomes, if randomized trial data are available, EPCs may choose to start with a rating of … EPC, Evidence-based Practice Center; RCT, randomized controlled trial. 14 Table 2. … controlled trial; SOE, strength of evidence. … Required domains and their definitions EPC, Evidence-based Practice Center; RCT, randomized controlled … trial.

411. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
     December 09, 2009 - Inclusion criteria Study design* Randomized controlled trials, nonrandomized controlled trials, cohort … acute care to subacute care) Outcomes None of the aforementioned outcomes are available from the trial … We will also search online trial registers (e.g. … Randomized controlled trials, nonrandomized controlled trials, cohort studies (prospective or retrospective … Randomized controlled trials, nonrandomized controlled trials, cohort studies (prospective or retrospective

412. Colorectal-Surgery-Preparation Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
     March 26, 2013 - tool for randomized controlled trials.23 For nonrandomized comparative studies and single-group studies … Thus, randomized controlled trials will be graded as having a high, medium, or low risk of bias, and … Single-blinded randomized trial of mechanical bowel preparation for colon surgery with primary intraperitoneal … trial. … A generalized linear modeling framework for pairwise and network meta-analysis of randomized controlled

413. Topic-Brief2-Opioid-Withdrawal (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief2-opioid-withdrawal.pdf
     April 01, 2021 - It included 49 studies (the Frank et al systematic review, 5 randomized trials, 10 controlled observational … One small (n=35) randomized trial compared a tapering schedule of 10 percent per week versus usual … controlled trial. … Prescription opioid taper support for outpatients with chronic pain: a randomized controlled trial. … Randomized Controlled Trial With 12 Months Follow up (TOPIO). In: ClinicalTrials.gov.

414. Topic-Brief2-Opioid-Withdrawal (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief2-opioid-withdrawal.pdf
     April 01, 2021 - It included 49 studies (the Frank et al systematic review, 5 randomized trials, 10 controlled observational … One small (n=35) randomized trial compared a tapering schedule of 10 percent per week versus usual … controlled trial. … Prescription opioid taper support for outpatients with chronic pain: a randomized controlled trial. … Randomized Controlled Trial With 12 Months Follow up (TOPIO). In: ClinicalTrials.gov.

415. S143 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s143.pdf
     October 01, 2007 - In a randomized drug trial, the allocation of subjects to treatment and control groups at random leads … The result closer to the randomized trials was achieved through close matching on the propensity score … Sacks FM, Pfeffer MA, Moye LA, et al; Cholesterol and Recurrent Events Trial Investigators. … Study of cholesterol lowering with simvastatin in 20,536 high-risk individ- uals: a randomised placebo-controlled … trial.

416. Diagnosis and Management of Gout: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/gout_clinician.pdf
     January 01, 2017 - ACTH = adrenocorticotropic hormone; N = number; NSAIDs = nonsteroidal anti-inflammatory drugs; RCT = randomized … controlled trial; SOE = strength of evidence † The known anti-inflammatory action of these agents was … controlled trial; SOE = strength of evidence; ULT = urate-lowering therapy Table 4: Adverse Effects … should minimize clinical gout sequelae, the exact target level has yet to be formally evaluated in randomized … controlled trials, and guidelines vary in the recommended target levels.

417. Noninvasive, Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
     September 20, 2017 - controlled trials (RCTs) for specific interventions and conditions. … standards for a randomized controlled trial. … controlled trials or high quality systematic reviews of randomized controlled trials published in … controlled trial or systematic reviews) 29 27 and (random* or systematic or meta*).ti,ab. 30 28 or … controlled trial or systematic reviews) 35 33 and (random* or systematic or meta*).ti,ab.

418. Obesity (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1306.pdf
     July 01, 2013 - , double-blind, placebo-controlled multicenter phase III trial (CONQUER) that evaluated the changes … controlled trial, SCALE™ (Satiety and Clinical Adiposity-Liraglutide Evidence in Non- diabetic and … Multicenter, placebo-controlled trial of lorcaserin for weight management. … Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus … A one- year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM

419. AHRQ Evidence-based Practice Center Program Research Gaps Summary: Primary Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
     March 01, 2022 - • Large high-quality randomized controlled trials to evaluate new treatment options of whole-body … • Large high-quality randomized controlled trials to evaluate new treatment options of whole-body … • Multisite trial-based studies, where patients are randomized to standard management, telehealth … • Randomized controlled trials with adequate power to compare risk of clinical fracture endpoints … • Randomized controlled trials with adequate power to compare risk of clinical fracture endpoints

420. Primary Hypofractionated Radiation Therapy for Localized Prostate Cancer: Research Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
     April 17, 2024 - Several major randomized controlled trials (RCTs) have compared active treatments to active surveillance … , such as the Prostate Cancer Intervention Versus Observation Trial (PIVOT),8 which indicated the potential … The study designs considered are randomized controlled trials and comparative cohort studies that adequately … Randomized controlled trials KQs 3–5. Randomized controlled trials. … controlled trial comparing radical prostatectomy to watchful waiting for men with clinically localized