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effectivehealthcare.ahrq.gov/sites/default/files/related_files/tympanostomy-tubes-executive-170523.pdf
May 01, 2017 - controlled trial; Some publications reported data from the same study. … RCT=Randomized Control Trial; NRCS=Nonrandomized Comparative Trial; CI=Confidence Interval
The forest … Network of treatment comparisons (RCTs)
RCT= Randomized Control Trial; PO=Oral The network plot consists … clinical trial. … Water
precautions and tympanostomy tubes: a randomized, controlled
trial.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-4.pdf
July 01, 2019 - Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of
randomised controlled … Where:
wi = study weight (inverse variance)
xi = observed effect size of each trial
�𝑥𝑥𝑤𝑤 = summary … graphs the accumulation of evidence across
trials, incorporating information up to and including each trial … Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled
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effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - controlled trial, SCALE™ (Satiety and Clinical Adiposity-Liraglutide Evidence in Non-
diabetic and … Controlled-release phentermine/topiramate in
severely obese adults: a randomized controlled
trial … Multicenter, placebo-controlled trial of
lorcaserin for weight management. … A one-
year randomized trial of lorcaserin for weight
loss in obese and overweight adults: the
BLOSSOM … Randomized placebo-controlled clinical trial of
lorcaserin for weight loss in type 2 diabetes
mellitus
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - Scope
To inform clinical decisions about care we focused on
evidence from randomized controlled trials … Restricting the review to randomized controlled trials
limited ability to detect the full range of harms … Uterine artery embolization versus
surgery for symptomatic uterine fibroids: a randomized controlled … Midterm clinical and first reproductive results of a randomized
controlled trial comparing uterine fibroid … , and controlled clinical trial.
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effectivehealthcare.ahrq.gov/sites/default/files/masks-surveillance-2-appendix-table-a-1.xlsx
April 09, 2020 - Randomized controlled trials of mask use
Author
Registry # Publication Year Title Date Retrieved Source … trial April 9 2020 PloS One. 2010;5(11):e13998. … /744899/facemasks-hand-hygiene-prevent-influenza-transmission-households-cluster-randomized-trial Cluster … trial April 9 2020 JAMA. 2009;302(17):1865-71. … controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand
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effectivehealthcare.ahrq.gov/sites/default/files/Masks-appendix-table-b-1-surveillance-report.xlsx
April 09, 2020 - Randomized controlled trials of mask use
Author
Registry # Publication Year Title Date Retrieved Source … trial April 9 2020 PloS One. 2010;5(11):e13998. … /744899/facemasks-hand-hygiene-prevent-influenza-transmission-households-cluster-randomized-trial Cluster … trial April 9 2020 JAMA. 2009;302(17):1865-71. … controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand
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effectivehealthcare.ahrq.gov/sites/default/files/masks-appendix-table-b-1-version-2.xlsx
April 09, 2020 - Randomized controlled trials of mask use
Author
Registry # Publication Year Title Date Retrieved Source … trial April 9 2020 PloS One. 2010;5(11):e13998. … /744899/facemasks-hand-hygiene-prevent-influenza-transmission-households-cluster-randomized-trial Cluster … trial April 9 2020 JAMA. 2009;302(17):1865-71. … controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-appendix-table-b-1-version-1.xlsx
April 09, 2020 - Randomized controlled trials of mask use
Author
Registry # Publication Year Title Date Retrieved Source … trial April 9 2020 PloS One. 2010;5(11):e13998. … /744899/facemasks-hand-hygiene-prevent-influenza-transmission-households-cluster-randomized-trial Cluster … trial April 9 2020 JAMA. 2009;302(17):1865-71. … controlled trial of hand washing and face masks to reduce influenza transmission in Bangkok, Thailand
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effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
January 01, 2011 - experimental or
quasi-experimental designs, such as interrupted time
series,1 designed delays,2 cluster randomized … trials,
individually randomized trials, pragmatic trials, or
adaptive trials. … The limited generalizability of
findings from randomized controlled trials (RCTs),
such as to older … A two-stage trial design for testing
treatment, self-selection and treatment preference
effects. … Why do
we need some large, simple randomized trials?
Statistics in Medicine. 1984;3:409–20.
8.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
June 01, 2022 - Across all Key Questions, eight randomized controlled trials, one nonrandomized
trial, and seven observational … contraceptive pills; PTSD=post-traumatic stress
disorder; STI=sexually transmitted infection; RCT=randomized … controlled trial
6
Strengths and Limitations
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-treatment-future_research.pdf
February 01, 2012 - Randomized Controlled Trials
Any future trials of CPAP or MAD should study clinical outcomes. … Randomized Controlled Trials
In general, there is limited or no need for future randomized controlled … Randomized Controlled Trials
Value of Study Design
Only one of 89 trials studied clinical outcomes … The required total sample size (1:1 ratio in a
two-arm randomized controlled trial [RCT]) for each value … controlled trial
A-1
Appendix A.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-225-substance-abuse-adolescents-comments.pdf
May 21, 2020 - APA Results In the first sentence on p. 81 did you mean “randomized
controlled trials”? … It is currently written as “randomized
comparative trials.”
Thank you. … We have changed to
“randomized controlled trials”.
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effectivehealthcare.ahrq.gov/sites/default/files/study-design-considerations-chapter-2.pptx
January 01, 2013 - Self-controlled designs include case-crossover, case-time-controlled, and self-controlled case series … The limited generalizability of findings from a randomized controlled trial, for example, to older adults … Cohort designs are easy to conceptualize and are readily compared to the randomized controlled trial, … Poor health, such as frailty, is also associated with nonadherence in randomized controlled trials; thus … , those adhering to randomized treatment will appear to have better outcomes, including those adhering
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/polyunsaturated-fatty-protocol.pdf
January 01, 2024 - Note that the term “effect” does not
necessarily imply restriction to randomized controlled trial evidence … Criteria Exclusion Criteria
Design Key Question 1
• Studies of adults
o Parallel or cross-over randomized … controlled trials (RCTs)
n ≥25/group*
• Studies of children
o Parallel or cross-over RCTs
… Search strategies will include filters to restrict to randomized controlled trials (RCTs) and
systematic … Controlled Trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
January 01, 2024 - Note that the term “effect” does not
necessarily imply restriction to randomized controlled trial evidence … Dietary cholesterol intake
None
Design Key Question 1
• Studies of adults
o Parallel or cross-over randomized … controlled trials (RCTs)
n ≥25/group*
• Studies of children
o Parallel or cross-over RCTs
… Search strategies will include filters to restrict to randomized controlled trials
and systematic reviews … Controlled Trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-screening_research-protocol.pdf
October 20, 2011 - to identify systematic reviews, we will search the Cochrane Databases of
Systematic Reviews and Controlled … Controlled Trials, Clinical Trial Results, WHO Trial Registries),
grants databases (NIH RePORTER, … Methodological Risk of Bias of Individual Studies
We will assess the risk of bias of systematic reviews, randomized … Carotid Surgery
Trial Collaborative Group. … Evaluating non-randomized intervention studies. Health Technol Assess 2003;7(27):iii-x, 1-173.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/calcineurin-inhibitor_research-protocol.pdf
October 08, 2014 - However, a recent publication reported that
pooled data from three large randomized controlled trials … The trial
will be rated as Moderate risk of bias if it does not meet the criteria for either Low or … not predict
the risk of acute rejection after renal
transplantation: a pooled analysis from three
randomized-controlled … study filter
('randomized controlled trial'/exp OR 'randomized controlled trial' OR
'randomization … study'/exp OR 'controlled study' OR 'clinical trial'/exp OR 'clinical trial' OR
'comparative study
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
November 02, 2018 - controlled trial, ROC = receiver operating characteristics, SAE = serious adverse
events, SPECT = single-photon … Trials (CENTRAL) to identify randomized controlled
trials, nonrandomized controlled clinical trials … or clinical study or clinical trial, all or clinical trial, phase i
or clinical trial, phase ii or … clinical trial, phase iii or clinical trial, phase iv or clinical trial or
controlled clinical trial … or randomized controlled trial) (587)
9 6 not 7 (3626)
10 8 or 9 (4213)
11 limit 10 to
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effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1312.pdf
December 01, 2013 - ,
double-blind, placebo-controlled, multicenter phase III trial (CONQUER) that evaluated the
changes … controlled trial, SCALE™ (Satiety and Clinical Adiposity-Liraglutide Evidence in Non-
diabetic and … Multicenter, placebo-controlled trial of lorcaserin
for weight management. … Randomized placebo-controlled clinical trial of
lorcaserin for weight loss in type 2 diabetes
mellitus … A one-
year randomized trial of lorcaserin for weight loss
in obese and overweight adults: the BLOSSOM
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
April 23, 2019 - blinded
phase 2 clinical trial. … blinded
phase 2 clinical trial. … Vertebral fractures
after discontinuation of denosumab: A post hoc analysis of the
randomized placebo-controlled … However, it is
unrealistic to consider a new long-term placebo-
controlled, fracture end point trial … placebo-controlled FREEDOM
Trial and its extension.