-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/mhs-IV-rapid-response-deprescribing.pdf
February 01, 2024 - All but one of the original research
studies was a randomized trial. … controlled trial
Outpatient
clinics
(Primary
care)
Age ≥65 years
prescribed
anticholinergics … Deprescribing in the Pharmacologic
Management of Delirium: A Randomized
Trial in the Intensive Care … controlled trial
in older adults in a preoperative setting. … randomised controlled trial-outcomes of
the Opti-med study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
April 23, 2019 - blinded
phase 2 clinical trial. … blinded
phase 2 clinical trial. … Vertebral fractures
after discontinuation of denosumab: A post hoc analysis of the
randomized placebo-controlled … However, it is
unrealistic to consider a new long-term placebo-
controlled, fracture end point trial … placebo-controlled FREEDOM
Trial and its extension.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
November 30, 2011 - Controlled Trials, Clinical Trial Results, WHO Trial Registries), grants databases
(NIHRePORTER, … telaprevir.mp OR boceprevir.mp
Hepatitis C and
treatment
1 AND 2 15019
Methods Limit (randomized … controlled trial or controlled clinical trial or meta analysis or
review).pt. or clinical trials as … sustained virological response than peginterferon alpha-2b in chronic
hepatitis C: systematic review of randomized … Evaluating non-randomized intervention studies.
Health Technol Assess. 2003;7(27):iii-x, 1-173.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/structured-handoff-rapid-research.pdf
January 01, 2025 - Two
systematic reviews and two new original research studies (one a randomized
controlled trial) provided … RCT = randomized controlled trial. SBAR = situation, background, assessment, recommendation. … RCT = randomized controlled trial. SIGNOUT? = sick or DNR? … A randomized controlled pilot study. … Controlled
trial to improve resident sign-out in a
medical intensive care unit.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-247-interventional-treatments-acute-chronic-pain-evidence-summary_0.pdf
September 01, 2021 - Benefits are smaller in
sham compared with usual care controlled trials and larger in trials of patients … Methods
Electronic databases (Ovid® MEDLINE®, PsycINFO®, the Cochrane Central Register
of Controlled … Randomized controlled trials (RCTs) of populations undergoing the designated
interventional procedures … Effects
of vertebroplasty were reduced in sham versus usual care controlled trials and larger in
trials … However, an important limitation of the evidence is the absence of
sham-controlled trials of kyphoplasty
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/long-term-care-adults_research-protocol.pdf
December 20, 2011 - Criteria for Inclusion/Exclusion of Studies in the Review
Inclusion Criteria
Randomized controlled … controlled trials as topic/ (77322)
28 randomized controlled trial/ (319749)
29 random allocation … / (469154)
33 clinical trial, phase i.pt. (11784)
34 clinical trial, phase ii.pt. (18612) … 35 clinical trial, phase iii.pt. (6631)
36 clinical trial, phase iv.pt. (654)
37 controlled … clinical trial.pt. (83741)
38 randomized controlled trial.pt. (319749)
39 multicenter study.pt
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-apbi-breast-cancer.pdf
April 01, 2017 - , 1184 patients were enrolled
in a phase 3, noninferiority trial and were randomized to
WBI plus a tumor … Breast and Bowel Project B39/Radiation Therapy Oncology
Group (RTOG) 0413 trial5 and Randomized Trial … The RTOG 9804 randomized clinical trial included
women with screen-detected DCIS, low to intermediate … Most important,
the Randomized Trial of Accelerated Partial Breast
Irradiation trial randomized 2135 … RTOG 9804: a prospective
randomized trial for good-risk ductal carcinoma in situ comparing
radiotherapy
-
effectivehealthcare.ahrq.gov/sites/default/files/study-eligibility-criteria.ppt
January 01, 2000 - Types of Studies To Be Included
Limit to randomized controlled trials? … Types of Studies To Be Included
Limiting a review to randomized controlled trials is appropriate for … Notice that the question focuses on “efficacy” (which suggests the inclusion of randomized controlled … Exercise 2: Implications of a Question That Requires Narrow Criteria
Efficacy: randomized controlled … Only 3 of 169 studies were randomized controlled trials; 122 were case series.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
October 27, 2017 - controlled trial; TIA = transient ischemic attack; VKA = Vitamin K antagonists. … controlled trial
SRDR Systematic Review Data Repository
TIA transient ischemic attack
TEE transthoracic … controlled trial[Publication Type] OR controlled clinical trial[Publication Type] OR
randomized[tiab … Controlled Trial"[Publication Type] OR "Controlled Clinical Trial"[Publication Type]
OR randomized … Controlled Trial"[Publication Type] OR "Controlled Clinical Trial"[Publication Type]
OR randomized
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/asthma-treatment_executive.pdf
May 01, 2011 - controlled trials (RCTs) except one, which was
a randomized crossover trial.22 We excluded the remaining … Buteyko breathing techniques in
asthma: a blinded randomised controlled trial. … Randomized trial of the effect
of an integrative medicine approach to the management of asthma
in adults … controlled trial. … Breathing retraining
for dysfunctional breathing in asthma: a randomised controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/obesity-horizon-scan-high-impact-1406.pdf
June 01, 2014 - controlled trial, SCALE™ (Satiety and Clinical Adiposity-Liraglutide Evidence in Non-
diabetic and … Controlled-release phentermine/topiramate in
severely obese adults: a randomized controlled
trial … Multicenter, placebo-controlled trial of
lorcaserin for weight management. … A one-
year randomized trial of lorcaserin for weight
loss in obese and overweight adults: the
BLOSSOM … Randomized placebo-controlled clinical trial of
lorcaserin for weight loss in type 2 diabetes
mellitus
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-2006_appendixes.pdf
January 01, 2006 - (TARGET),
cardiovascular outcomes: randomised controlled
trial. … patients per
trial was 95,
with a range
from 9 to 455. … Trial duration 4
weeks to 13 months. … placebo arms, 2
randomized parallel-
group double-blinded
trials, 2 randomized
crossover trials, … and 1
randomized placebo-
controlled double-blinded
trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-202-thermoplasty-comments.pdf
December 14, 2017 - to be
weak, and agree that a blinded and
randomized trial was appropriate for
assessing impact on … treatment effect and safety can be made based on
five-year follow-up from all three randomized controlled … Six trials, including three randomized
controlled trials (RCTs) (n=432)18-20
and their 5-year, single-arm … Both the comparisons with standard of care and the sham
controlled trial were done well and all have … As noted above, only one sham-controlled trial of BT
has been conducted thus far.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-256-telehealth-women-preventive-services-executive-summary.pdf
June 01, 2022 - Across all Key Questions, eight randomized controlled trials, one nonrandomized
trial, and seven observational … contraceptive pills; PTSD=post-traumatic stress
disorder; STI=sexually transmitted infection; RCT=randomized … controlled trial
6
Strengths and Limitations
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
January 01, 2015 - controlled trial. … HARMONY 3:
104-week randomized, double-blind, placebo- and active-controlled
trial assessing the efficacy … In macroVascular Events): a randomised controlled trial. … United Kingdom
Prospective Diabetes Study 24: a 6-year, randomized, controlled
trial comparing sulfonylurea … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/dental-post-transplant-complications-rapid-research.pdf
May 01, 2025 - ROBINS-I gave non-randomized controlled interventional studies a score of low,
moderate, serious, or … A Pilot Randomized Controlled
Trial of an Oral Care Intervention to Reduce
Mucositis Severity in Stem … , Placebo-Controlled
Trial. … controlled trial
RoB Risk of bias
SME Subject matter expert
SR Systematic review
USPSTF United … controlled trial of an oral care intervention
to reduce mucositis severity in stem cell transplant
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
September 19, 2014 - We rated the quality of each randomized
trial based on the methods used for randomization,
allocation … One randomized trial found no
difference between more liberal dose escalation versus
maintenance of … Abuse, addiction Low
No randomized trial evaluated risk of opioid abuse,
addiction, and related outcomes … Nonetheless, pragmatic and other non-traditional
randomized trial approaches could be used to address … A randomized trial
of 2 prescription strategies for opioid treatment of chronic
nonmalignant pain.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - controlled trials (RCTs) and
controlled clinical trials (CCTs) of screening for and
monitoring and … However, we identified no RCTs that randomized
individuals without known CKD to CKD screening,
or randomized … Angiotensin converting enzyme inhibitor
AKI Acute kidney injury
ARB Angiotensin receptor blocker
CCT Controlled … controlled trial
18
References
1. … Statins and all-cause mortality
in high-risk primary prevention: a meta-analysis of 11 randomized
controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
August 01, 2012 - controlled trial; rhGH recombinant human growth hormone
31
References
1. … A multi-center controlled trial of growth
hormone treatment in children with cystic
fibrosis. … controlled trial[pt] OR controlled clinical trial[pt] OR
randomized[tiab] OR placebo[tiab] OR drug … controlled trial[pt] OR controlled clinical trial[pt] OR
randomized[tiab] OR placebo[tiab] OR drug … clinical trial
randomized 68
participants to
receive rhGH 12
months, followed by
6 months followup
-
effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_disposition-comments.pdf
January 01, 2015 - Also, losses to followup were at least
twice as high in ADOPT vs. the other
randomized controlled trial … and also provide risk
differences from the randomized controlled
trials. … endpoint results from a randomized, double-blind,
placebo-controlled, trial in patients with type … on metformin alone:
long-term (52-week) extension of a 52-week
randomised controlled trial. … We have added
discussion of the three placebo-controlled
randomized controlled trials (EXAMINE,
TECOS