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effectivehealthcare.ahrq.gov/sites/default/files/pdf/stroke-afib-update_research-protocol-amended.pdf
October 27, 2017 - controlled trial; TIA = transient ischemic attack; VKA = Vitamin K antagonists. … controlled trial
SRDR Systematic Review Data Repository
TIA transient ischemic attack
TEE transthoracic … controlled trial[Publication Type] OR controlled clinical trial[Publication Type] OR
randomized[tiab … Controlled Trial"[Publication Type] OR "Controlled Clinical Trial"[Publication Type]
OR randomized … Controlled Trial"[Publication Type] OR "Controlled Clinical Trial"[Publication Type]
OR randomized
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
March 01, 2024 - Thirty-one randomized controlled trials (RCTs) and 23 controlled observational studies met
inclusion … Convalescent
plasma for hospitalized patients with COVID-19:
an open-label, randomized controlled trial … A randomized double-blind controlled trial of
convalescent plasma in adults with severe
COVID-19. … , Placebo-Controlled Trial. … Randomized Controlled Trial of Early Outpatient
COVID-19 Treatment with High-Titer
Convalescent Plasma
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR
randomised[tiab] OR randomization … controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR
randomised[tiab] OR randomization … controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR
randomised[tiab] OR randomization … Nonpharmacological interventions for
ADHD: systematic review and meta-analyses of randomized controlled … controlled trial
VII.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
December 14, 2010 - number of patients excluded from
efficacy analyses, expressed as a proportion of the number of patients randomized … Playfair J et al. (2008) Adjustable gastric banding and
conventional therapy for type 2 diabetes: a randomized … controlled trial. … Adjustable Gastric
Banding versus Laparoscopic Roux-en-Y Gastric Bypass: 5 years results of a
prospective randomized … trial.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/rt-bone-metatases-final-protocol-amendment.pdf
August 10, 2022 - controlled
trial; RT = radiation therapy; SBRT = stereotactic radiation therapy. … Study Designs: We will use a best evidence approach29 and randomized controlled trials
(RCTs) will be … ) : First results of
a randomized controlled trial. … controlled trial; RT = radiation therapy; SBRT = stereotactic radiation
therapy. … controlled clinical
trial[pt])) OR (randomized controlled trial[pt])
NSRI hedge: ((((("Cohort Studies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/osteoarthritis-knee-future_research.pdf
February 01, 2013 - Randomized controlled trials (RCTs) are the best approach. … Randomized controlled trials (RCTs) are the best approach. … A randomized controlled trial to investigate the effects of
water-based exercise to improve falls risk … , controlled
trial. … Controlled Trial
Other: Patient education programme
NCT00988468 Manual Therapy Versus Exercise on
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
March 01, 2016 - Randomized controlled trials are best suited to provide data for comparative effectiveness
and there … controlled trial (KQs 1, 2)
• Any (KQs 3, 4)
Other • Original research (KQs 1 … controlled trials. … We will assess reporting bias of randomized
controlled trials by examining outcomes of trials as reported … controlled trial
SERM Selective estrogen receptor modulator
SPRM Selective progesterone
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
August 01, 2016 - The former systematic review
included 29 randomized controlled trials (RCTs) and 10 observational studies … medium;
IV = intravenous; LOCM = low-osmolar contrast medium;
NR = not reported; No. = number; RCT = randomized … controlled trial;
SOE = strength of evidence
a Based on statistical significance for meta-analysis … LOCM = low-osmolar contrast medium;
NR = not reported; NAC = n-acetylcysteine; No. = number;
RCT = randomized … controlled trial; SOE = strength of evidence
a Based on statistical significance for meta-analysis
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pelvic-pain-therapies-future_research.pdf
January 01, 2015 - controlled trial. … Botulinum toxin type A for chronic pain and
pelvic floor spasm in women: a randomized
controlled trial … Randomized controlled trial of
depot leuprolide in patients with chronic
pelvic pain and clinically … A
randomized clinical trial to compare two
different approaches in women with chronic
pelvic pain. … A controlled trial of arthroscopic surgery for
osteoarthritis of the knee.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
January 12, 2022 - controlled trial; QOL = quality of
life; SF = short form health survey (12 or 36 items); VAS = visual … Study Designs: Randomized controlled trials (RCTs) will be included for all key
questions. … controlled trials. … controlled clinical trial[pt])) OR
(randomized controlled trial[pt])
Clinical Trials (specific) … "Controlled Clinical Trial"[Publication Type]) OR
"Case-Control Studies"[Mesh])) OR (("Evaluation Studies
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_clinician.pdf
July 01, 2017 - update the evidence
in light of the more recent literature published on the topic
and included both randomized … controlled trials (RCTs) and
observational studies. … low-density lipoprotein cholesterol;
FA = fatty acid; NA = not available; Obs = observational study; RCT = randomized … controlled trial; SBP = systolic blood pressure
a Studies that reported combined EPA and DHA were analyzed … controlled trial; SBP = systolic blood pressure
Gaps in Knowledge and Limitations of the
Evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
June 15, 2011 - Prevention of Recurrent Stone Disease
Many randomized controlled trials (RCTs) have studied dietary … Grey literature searching may include searches of regulatory data, trial registries, and
abstracts … clinical trial or meta analysis or randomized controlled trial)
12 limit 10 to systematic reviews … 13 11 or 12
14 exp meta-analysis/
15 exp randomized controlled trials/ or systematic review.mp … .
16 exp controlled clinical trial/
17 or/14-16
18 10 and 17
19 13 or 18
20 limit 19 to
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
January 01, 2007 - controlled trial. … controlled trial(s)
45
Table 12. … External validity of randomised
controlled trials: "to whom do the results of this trial
apply?". … A
randomized, double-blind, controlled, parallel-
group comparison of perindopril and candesartan in … Eprosartan versus
enalapril in elderly patients with hypertension: a
double-blind, randomized trial
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - However, in 2013, a re-
analysis of the pivotal trial substantially reduced the FDA’s concern leading … ESLD = end-stage liver disease; ESRD = end-stage renal disease; KQ = Key Question; RCT = randomized controlled … trial
* Of note, some outcomes could be classified as either safety or long-term clinical outcomes … Results of a
reevaluation of cardiovascular outcomes in the RECORD trial. … controlled trial
SGLT-2 inhibitor = sodium-glucose co-transporter 2 inhibitor
VII.
-
effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
January 01, 2013 - Guiding Principles: Risk of Bias Example
Drug comparisons in randomized controlled trials (RCTs), with … controlled trial
Outcome
Strength of Evidence (SOE) Number of Studies (Subjects)
SOE Domain
Risk … controlled trial
Outcome
Strength of Evidence (SOE) Number of Studies (Subjects)
SOE Domain
Risk … For example, for mortality, randomized controlled trials are separate from retrospective cohort studies … This table shows that one fair-quality randomized controlled trial (RCT) with 80 subjects reported mortality
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
October 01, 2011 - Chondroitins 4 and 6 sulfate in
osteoarthritis of the knee: a randomized,
controlled trial. … trial. … clinical trial. … The trial we performed was designed as a
randomized, double-blind, placebo controlled
clinical trial … We performed a pilot, multicentre, randomized,
double-blind, controlled trial in knee OA patients
with
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-2.pdf
February 01, 2018 - ► Data from clustered randomized trials should be adjusted for the design effect.*
*More information … Where:
N = total trial sample size
Ratio of means
• Ratio of means (RoM) is an alternative to the … Special topics:
Crossover trials
• In a crossover trial all participants receive both the treatment … errors.5
► Generally the correlation is positive, resulting in smaller SEs than in a
standard parallel trial … trial of the same size
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research-protocol.pdf
September 02, 2016 - Matching Studies
We will match randomized controlled trials (RCTs) identified in CT.gov with those … Recommendations for examining and
interpreting funnel plot asymmetry in meta-analyses of randomised controlled … screening”[tiab] OR “preimplantation testing”[tiab] OR “preimplantation genetic testing”[tiab]
#3 (randomized … controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR
randomised[tiab] OR randomization … [tiab] OR randomisation[tiab] OR randomly[tiab] OR
Clinical trial[pt] OR “clinical trial”[tiab] OR “
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rapid-social-isolation-older-adults-final.pdf
February 01, 2019 - controlled trial. … controlled trial. … controlled trial. … controlled trial. … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
April 17, 2024 - Several major randomized controlled trials (RCTs)
have compared active treatments to active surveillance … , such as the Prostate Cancer Intervention Versus
Observation Trial (PIVOT),8 which indicated the potential … The study
designs considered are randomized controlled trials and comparative cohort studies that
adequately … Randomized controlled trials
KQs 3–5. Randomized controlled trials. … controlled trial comparing radical prostatectomy to watchful waiting for men with
clinically localized