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Total Results: 1,523 records

Showing results for "randomized controlled trial".

341. Grading_didactic_faculty_approved (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
     January 01, 2013 - Guiding Principles: Risk of Bias Example Drug comparisons in randomized controlled trials (RCTs), with … controlled trial Outcome Strength of Evidence (SOE) Number of Studies (Subjects) SOE Domain Risk … controlled trial Outcome Strength of Evidence (SOE) Number of Studies (Subjects) SOE Domain Risk … For example, for mortality, randomized controlled trials are separate from retrospective cohort studies … This table shows that one fair-quality randomized controlled trial (RCT) with 80 subjects reported mortality

342. Transparency of Reporting Requirements: Tympanostomy Tubes (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-tympanostomy_research-protocol.pdf
     September 02, 2016 - A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints. … Empirical evidence for selective reporting of outcomes in randomized trials: comparison of protocols … Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research. … controlled trials • Nonrandomized comparative studies, prospective or retrospective • Observational … controlled trials.

343. Rapid Evidence Product: Adverse Events Associated With COVID-19 Pharmaceutical Treatments (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments-rapid-review.pdf
     March 01, 2024 - Thirty-one randomized controlled trials (RCTs) and 23 controlled observational studies met inclusion … Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial … A randomized double-blind controlled trial of convalescent plasma in adults with severe COVID-19. … , Placebo-Controlled Trial. … Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma

344. Comparative Effectiveness and Safety of Analgesics for Osteoarthritis—An Update of the 2006 Report. (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain-disposition-120516.pdf
     October 01, 2011 - Chondroitins 4 and 6 sulfate in osteoarthritis of the knee: a randomized, controlled trial. … trial. … clinical trial. … The trial we performed was designed as a randomized, double-blind, placebo controlled clinical trial … We performed a pilot, multicentre, randomized, double-blind, controlled trial in knee OA patients with

345. Layout 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_executive.pdf
     July 01, 2009 - Data from three fair quality RCTs with fewer than 100 patients in each trial did not show significant … trial has examined the effect of catheter ablation on the risk of stroke or death. … Only one small RCT suggested that first-line RFA (prior to a trial of AADs) may be of benefit for patients … Only randomized controlled trials could receive a “good” grade. … controlled trial; RFA=radiofrequency catheter ablation; WACA=wide area circumferential ablation.

346. Microsoft Word - Comp Eff 10.doc (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
     January 01, 2007 - controlled trial. … controlled trial(s) 45 Table 12. … External validity of randomised controlled trials: "to whom do the results of this trial apply?". … A randomized, double-blind, controlled, parallel- group comparison of perindopril and candesartan in … Eprosartan versus enalapril in elderly patients with hypertension: a double-blind, randomized trial

347. Transparency of Reporting Requirements: Management of Infertility (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research-protocol.pdf
     September 02, 2016 - Matching Studies We will match randomized controlled trials (RCTs) identified in CT.gov with those … Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled … screening”[tiab] OR “preimplantation testing”[tiab] OR “preimplantation genetic testing”[tiab] #3 (randomized … controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab] OR randomised[tiab] OR randomization … [tiab] OR randomisation[tiab] OR randomly[tiab] OR Clinical trial[pt] OR “clinical trial”[tiab] OR “

348. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
     February 10, 2010 - controlled trials  Controlled clinical trials  Comparative observational studies (prospective … controlled trials  Controlled clinical trials  Comparative observational studies (prospective … controlled trials  Controlled clinical trials KQ 1, KQ 2, and KQ 3:  Editorials, letters, nonsystematic … Administration Medical and Statistical Reviews and Authorized Medicines for the European Union), clinical trial … Such criteria include: adequate randomization methods (for randomized controlled trials [RCTs]), consideration

349. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation-ablation_disposition-comments.pdf
     October 01, 2010 - In November, results from a randomized trial of a similar patient population were presented at the AHA … To this end, even though it is statistically flawed, it may be reasonable to compare published controlled … The randomized trial recently reported to the FDA measured the same QoL endpoints, and produced similar … quality of life after circumferential pulmonary vein ablation for atrial fibrillation: outcomes from a controlled … Discussion In November, results from a randomized trial on the use of the NAVISTAR THERMOCOOL Catheter

350. Cervical Degenerative Disease Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cervical-degenerative-protocol.pdf
     January 12, 2022 - controlled trial; QOL = quality of life; SF = short form health survey (12 or 36 items); VAS = visual … Study Designs: Randomized controlled trials (RCTs) will be included for all key questions. … controlled trials. … controlled clinical trial[pt])) OR (randomized controlled trial[pt]) Clinical Trials (specific) … "Controlled Clinical Trial"[Publication Type]) OR "Case-Control Studies"[Mesh])) OR (("Evaluation Studies

351. Antipsychotics-Adults Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-adults_executive.pdf
     August 01, 2012 - We included studies if they: were randomized (RCTs) or nonrandomized controlled trials (nRCTs), or prospective … controlled trial; SANS = Scale for the Assessment of Negative Symptoms; SAPS = Scale for the Assessment … KQ = Key Question; RCT = randomized controlled trial KQ3: Medication-Associated AEs and Safety The findings … KQ = Key Question; RCT = randomized controlled trial; SoE = strength of evidence 10 We were unable … controlled trial aResponse rates were defined by authors of the primary studies and may have varied

352. Dietary-Supplements Surveillance (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_surveillance.pdf
     January 01, 2013 - One pragmatic trial in 19,934 women randomized to vitamin E plus aspirin versus aspirin alone for 10 … controlled trial; SCEPC: Southern California Evidence-based Practice Center; TG triglyceride; VLDL … , randomized trial. … Bays 201210 12-week multi-center randomized controlled double blinded trial of Icosapent ethyl( … One pragmatic trial in 19,934 women randomized to vitamin E plus aspirin versus aspirin alone for 10

353. Disposition of Comments for Evidence Report 224 Omega-3 Fatty Acids (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
     October 12, 2016 - Four-year follow-up of children born to women in a randomized trial of prenatal DHA supplementation … A randomized trial of docosahexaenoic acid supplementation during the third trimester of pregnancy. … A randomized controlled trial of long-chain polyunsaturated fatty acid supplementation of formula in … A randomized trial of visual attention of preterm infants fed docosahexaenoic acid until two months … controlled trial.

354. Kidney-Stone-Prevention Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/kidney-stone-prevention_research-protocol.pdf
     June 15, 2011 - Prevention of Recurrent Stone Disease Many randomized controlled trials (RCTs) have studied dietary … Grey literature searching may include searches of regulatory data, trial registries, and abstracts … clinical trial or meta analysis or randomized controlled trial) 12 limit 10 to systematic reviews … 13 11 or 12 14 exp meta-analysis/ 15 exp randomized controlled trials/ or systematic review.mp … . 16 exp controlled clinical trial/ 17 or/14-16 18 10 and 17 19 13 or 18 20 limit 19 to

355. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
     February 01, 2013 - One review included both randomized and “quasi-randomized controlled trials,” while the other review … included randomized controlled trials with at least 10 subjects per arm published in a variety of languages … controlled trial Population Inclusion criteria for the population(s) of interest should be defined … Food and Drug Administration; RCT = randomized controlled trial; SIP = scientific information packet … For example, when the evidence from randomized controlled trials that directly compare interventions

356. Management of Suspected Opioid Overdose With Naloxone by Emergency Medical Services Personnel - Executive Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-193-naloxone-executive-summary.pdf
     November 01, 2017 - controlled trials (RCTs) conducted in field settings … Randomized controlled trials in U.S. field settings that compare the FDA-approved IN formulations of … Randomized controlled trials could pose ethical and logistical challenges in field settings, such as … Randomized controlled trial comparing the effectiveness and safety of intranasal and intramuscular … a randomized clinical trial.

357. Contrast-Induced Nephropathy (CIN): Current State of the Evidence on Contrast Media and Prevention of CIN (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
     August 01, 2016 - The former systematic review included 29 randomized controlled trials (RCTs) and 10 observational studies … medium; IV = intravenous; LOCM = low-osmolar contrast medium; NR = not reported; No. = number; RCT = randomized … controlled trial; SOE = strength of evidence a Based on statistical significance for meta-analysis … LOCM = low-osmolar contrast medium; NR = not reported; NAC = n-acetylcysteine; No. = number; RCT = randomized … controlled trial; SOE = strength of evidence a Based on statistical significance for meta-analysis

358. The series of articles beginning with this issue of the Journal form the most up-to-date version of the Guide for Conducting Comparative Effectiveness Reviews (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-principles_methods.pdf
     August 01, 2009 - Centralization at the SRC of activities where EPC proficiency and skill vary, such as searching clinical trial … controlled trials (RCTs) to case reports. … of bias from confounding by indication and other threats to internal validity.40,42–47 The ideal trial … The evolution of the randomized controlled trial and its role in evidence-based decision making. … Should meta-analyses of interventions include observational studies in addition to randomized controlled

359. Methods Guide for Comparative Effectiveness Reviews - Expanded Guidance on Selected Quantitative Synthesis Topics (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
     March 01, 2013 - Although the use of a composite outcome as the primary outcome in a clinical trial can reduce sample … For example, Hansen et al.33 combined functional outcomes measured on different scales in placebo-controlled … Composite outcomes in randomized trials: greater precision but with greater uncertainty? … Testing for heterogeneity among the components of a binary composite outcome in a clinical trial. … Problems with use of composite end points in cardiovascular trials: systematic review of randomised controlled

360. Omega-3 Fatty Acids and Cardiovascular Disease: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/fatty-acids-cardiovascular-disease_clinician.pdf
     July 01, 2017 - update the evidence in light of the more recent literature published on the topic and included both randomized … controlled trials (RCTs) and observational studies. … low-density lipoprotein cholesterol; FA = fatty acid; NA = not available; Obs = observational study; RCT = randomized … controlled trial; SBP = systolic blood pressure a Studies that reported combined EPA and DHA were analyzed … controlled trial; SBP = systolic blood pressure Gaps in Knowledge and Limitations of the Evidence