-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
January 01, 2020 - and non-randomized controlled clinical trials;
prospective cohort studies with concurrent control … , time frames, country settings, study design; RCT = randomized
controlled trial; WIC = Special Supplemental … controlled trial. … ]) OR (controlled[title/abstract] AND
trial[title/abstract]) OR "controlled clinical trial"[publication … type] OR "Randomized Controlled
Trial"[Publication Type] OR "Single-Blind Method"[MeSH] OR "Double-Blind
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - part of
the conclusions of the original report might be out of date:
• New studies, especially new randomized … number of patients excluded from
efficacy analyses, expressed as a proportion of the number of patients randomized … outcomes without a minimum trial length. … The individual trial mean differences are weighted by both within-study variation and between-
study … Assessing the quality of reports of randomized
clinical trials: is blinding necessary?
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-learning-objectives-recommendations.pdf
July 01, 2019 - ► Data from clustered randomized trials should be adjusted for the design effect. … Meta-analysis of clinical trial safety data in a drug development program: Answers to frequently asked … Controlled Trials. … The results of direct and indirect treatment comparisons in meta-analysis of randomized controlled trials … Evaluation of networks of randomized trials. Stat Methods Med Res. 2008;17(3):279-301.
-
effectivehealthcare.ahrq.gov/sites/default/files/s5.pdf
October 01, 2007 - controlled trials (RCTs, using experimental de-
signs that may limit generalizability) or purely observational … Cluster randomized trials are especially valuable for
evaluating outcomes under conditions of actual … “Delayed de-
sign” approaches invoke randomized communities and clus-
ters of physician practices (such … Cluster randomized trials:
opportunities and barriers identified by leaders of eight health plans. … trial results.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glaucoma-screening_research-protocol.pdf
November 16, 2010 - controlled trials (RCTs), quasi-randomized
controlled trials, and observational studies (to include … If an outcome is
evaluated by at least one randomized controlled trial and by observational studies … , our evidence grade
will be based firstly on the randomized controlled trials and secondly on the … If an outcome is evaluated by one or no randomized controlled trials, our evidence grade will be
based … on the single randomized controlled trial and the best available observational study.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/sleep-apnea_surveillance.pdf
April 01, 2012 - controlled
trial. … Randomized
controlled trial comparing flexible and continuous
positive airway pressure delivery: effects … controlled trial. … ,
controlled trial. … or/1-6
randomized controlled trial.pt.
controlled clinical trial.pt.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/COVID-19-pharmaceutical-treatments.pdf
December 23, 2023 - non-serious
adverse events,
effectiveness outcomes,
Timing No restriction NA
Study
Design
Randomized … controlled trials, controlled
clinical trials, observational studies with
a comparison group, case-control … reported in
abbreviated format only
(e.g., conference abstract
rather than in a journal
publication, trial … following data will be abstracted
• Study identifier (author) and publication year
• Study design
Randomized … Controlled Trial (RCT)
Controlled Clinical Trial
Retrospective cohort
Prospective cohort
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
January 01, 2014 - The other trial (NCT01567150)
is an ongoing randomized controlled trial that evaluates wound protease … • Study Design: A randomized controlled trial would be best to minimize bias and
strengthen internal … • Study Design: The best design would be a prospective, randomized, double-blind
controlled trial. … • Study design: The best design is a randomized controlled trial. … The other trial
(NCT01567150) is an ongoing randomized controlled trial that evaluates wound protease
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/wheelchair-users-amended-protocol.pdf
June 21, 2019 - • Non-U.S. applicable
studies (See Appendix
B, Table B-1)
Study
designs
• Randomized controlled … trial versus
observational study, study location). … controlled trial
29. 27 and (random* or control* or trial or cohort or group* or arm*).ti,ab.
30 … controlled trial
39. 37 and (random* or control* or trial or cohort or group* or arm*).ti,ab.
40 … controlled trial
29. 27 and (random* or control* or trial or cohort or group* or arm*).ti,ab.
30
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-239-episodic-migraine-comments.pdf
December 29, 2020 - “Intranasal lidocaine for
acute migraine: A meta-analysis of
randomized controlled trials.” … Effects of Intravenous and Oral Magnesium
on Reducing Migraine: A Meta-analysis of
Randomized Controlled … A randomized, double-
blind, placebo-controlled study. … Solution, 25 Mg/ml)
in the Acute Treatment of Episodic Migraine:
Efficacy Results from Two Phase III
Randomized … , Double-blind, Placebo-
controlled Studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/atypical-antipsychotics-off-label-update_disposition-comments.pdf
September 01, 2011 - , placebo-controlled trial. … Quetiapine monotherapy in
chronic posttraumatic stress disorder: A randomized, double-blind, placebo-controlled … A randomized, double-blind,
placebocontrolled add-on trial of quetiapine in outpatients with bipolar … A randomized, double-blind, placebo-controlled pilot
study of quetiapine in outpatients with bipolar … , placebo-controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - controlled trials
• Nonrandomized controlled trials,
including quasi-experimental and
controlled … controlled trial; TC = total cholesterol; U.S. = United States
B. … controlled trials. … trial. … Risk Of Bias In Non-
randomized Studies - of Exposure (ROBINS-E). ROBINS-E tool; 2023.
34.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay-future_research.pdf
September 01, 2012 - A randomized controlled trial (RCT) would be ideal in all three cases,
since RCTs inherently would yield … Abbreviations: PCD=plasma cell dyscrasia, RCT = randomized controlled trial, SFLC=serum free light chain … Abbreviations: PCD=plasma cell dyscrasia, RCT = randomized controlled trial, SFLC=serum free light chain … Abbreviations: PCD=plasma cell dyscrasia, RCT = randomized controlled trial, SFLC=serum free light chain … Abbreviations: PCD=plasma cell dyscrasia, RCT = randomized controlled trial, SFLC=serum free light chain
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
November 01, 2021 - controlled trial. … , controlled trial. … controlled trial[pt] OR controlled clinical
trial[pt] OR randomized[tiab] OR randomised[tiab] OR randomization … controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab]
OR randomised[tiab] OR randomization … controlled trial[pt] OR controlled clinical trial[pt] OR randomized[tiab]
OR randomised[tiab] OR randomization
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
June 24, 2022 - NAM 2018 Lack of alignment between randomized controlled trial (RCT) endpoints and RWE endpoints, noting … NAM2019 Replicating randomized clinical trial results with observational databases can help establish … NAM2019 The cost of the trial?
NAM2019 The risk/benefit ratio of trial participation? … CMS Design_bias For observational, and in some cases randomized controlled trials, the method in that … CMS Design_bias For observational, and in some cases randomized controlled trials, the method in that
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_surveillance.pdf
August 01, 2012 - Several markers of epilepsy control were used in
randomized controlled trials to compare newer
versus … Many of these
controlled clinical trials used a crossover design or
randomized patients to either an … randomized controlled trial.pt.
2. controlled clinical trial.pt.
3. randomized.ab.
4. … Several markers of epilepsy control were used in
randomized controlled trials to compare newer versus … Many of these controlled clinical trials used a
crossover design or randomized patients to either an
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/epilepsy-medicine_surveillance.pdf
August 01, 2012 - Several markers of epilepsy control were used in
randomized controlled trials to compare newer
versus … Many of these
controlled clinical trials used a crossover design or
randomized patients to either an … randomized controlled trial.pt.
2. controlled clinical trial.pt.
3. randomized.ab.
4. … Several markers of epilepsy control were used in
randomized controlled trials to compare newer versus … Many of these controlled clinical trials used a
crossover design or randomized patients to either an
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/fecal-incontinence_research-protocol.pdf
November 30, 2014 - Study designs • Published systematic reviews, randomized clinical trials (RCTs), nonrandomized
controlled … KQ = key question; RCT = randomized controlled trial
B. … controlled trial
TBI Traumatic brain injury
VII. … controlled trials as topic/ (91978)
34 randomized controlled trial/ (370164)
35 random allocation … (88103)
44 randomized controlled trial.pt. (370164)
45 multicenter study.pt. (169875)
46 clinical
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
December 01, 2011 - Randomized controlled trials (RCTs) of at least 6
weeks’ duration and in adult study populations were … Insomnia
Six head-to-head trials (all fair quality) and one
placebo-controlled trial provide limited … Results from one good placebo-controlled trial showed no
difference between fluoxetine and placebo. … Key Question
IR Immediate release
MDD Major depressive disorder
NNT Number needed to treat
RCT Randomized … controlled trial
SRC Scientific Resource Center
SR Sustained release
SSNRI Selective serotonin norepinephrine
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
January 01, 2020 - To identify currently
funded or recently completed randomized controlled trials intended to reduce use … controlled trial
Note: Numbers in circles represent the position of Key Questions in the intervention … controlled trial[pt] OR controlled clinical trial[pt] OR random allocation[mh] OR double-blind
method … [mh] OR single-blind method[mh] OR clinical trial[pt] OR "clinical trial"[tiab] OR random[tiab] OR
randomized … trial” OR random OR randomized OR randomly OR
controlled OR control OR controls OR “interrupted time