-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
June 01, 2010 - controlled trials? … trial. … External validity of randomised
controlled trials: “to whom do the results of this
trial apply?” … controlled trial
13
Figure 1. … , controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/s50.pdf
October 01, 2007 - Results: PBE-CPI studies can uncover better practices more quickly
than randomized controlled trials … Although
randomized controlled trials (RCTs) are important to confirm
whether a new treatment causes … Comparison of Randomized Controlled Trials and Practice-Based Evidence for Clinical Practice Improvement … Studies
Variables Randomized Controlled Trials Clinical Practice Improvement
Patient variables Patient … It is impossible for a randomized
clinical trial to test all possible interactions among interven-
tions
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/acs-pci-adjunctive-devices_surveillance.pdf
April 01, 2013 - Eight of nine trials and one controlled
observational study found a nonsignificant
prolongation of … and aspiration
thrombectomy in patients with large anterior myocardial infarction: the INFUSE-AMI
randomized … trial. … Controlled Trial
Appendix C. … Eight of nine trials and one controlled observational study
found a nonsignificant prolongation of the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
February 01, 2018 - outcomes
• For rare binary events (e.g., adverse events), few or zero events may
occur in one or both trial … properties for meta-analyses
of rare binary outcome data.11
► This model assumes that outcomes of each trial … Decision Making 2: A Generalized Linear Modeling Framework for
Pairwise and Network Meta-analysis of Randomized … Controlled Trials. … Controlled Trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/trauma-interventions-maltreatment-child_executive.pdf
April 01, 2013 - trial; RCT = randomized controlled trial
From: Moher D, Liberati A, Tetzlaff J, Altman DG, The PRISMA … A multisite,
randomized controlled trial for children with sexual abuse-related
PTSD symptoms. … controlled trial. … Treating sexually abused
children: 1 year follow-up of a randomized controlled trial. … A follow-up study
of a multisite, randomized, controlled trial for children with
sexual abuse-related
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - Quantitative Analysis
Randomized controlled trials (RCTs) will be pooled separately from observational … To assess study design, we will
record if the study was a randomized controlled trial or an observational … controlled trial. … controlled trial. … Or/1-12
14. randomized controlled trial.pt.
15. controlled clinical trial.pt.
16. randomized.ab.
-
effectivehealthcare.ahrq.gov/sites/default/files/s29.pdf
October 01, 2007 - trials (CRTs) offer unique advan-
tages over standard randomized controlled clinical trials (RCTs) and … CRTs can offer unique advantages over standard
randomized controlled clinical trials (RCTs) and observa … Favor observational study or standard randomized
controlled trial. … Cluster randomized trial proposal should come from a reputable source. … A cluster randomized trial of a
sex education programme in Belize, Central America.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/topic-brief3-SUD.pdf
April 01, 2021 - A randomized trial of reduced versus full-dose buprenorphine/naloxone is
currently in progress (expected … • An analysis not included in the rapid review of a randomized trial of pregnant women
with opioid … Not included
in systematic
reviews
Abbreviations: N = number of subjects; RCT = randomized controlled … controlled trial. … controlled pilot
trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-brief3-SUD.pdf
April 01, 2021 - A randomized trial of reduced versus full-dose buprenorphine/naloxone is
currently in progress (expected … • An analysis not included in the rapid review of a randomized trial of pregnant women
with opioid … Not included
in systematic
reviews
Abbreviations: N = number of subjects; RCT = randomized controlled … controlled trial. … controlled pilot
trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - Controlled
Trials, Clinical Trial Results, WHO Trial Registries) and
grants databases (NIHRePORTER, … controlled trial comparing two doses of
peginterferon alpha-2b. … HCV-related
advanced fibrosis/cirrhosis: randomized controlled trial of
pegylated interferon alpha- … controlled trials. … controlled
trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-g-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
May 29, 2025 - Quality assessments of included randomized controlled trials
Author, Year Randomization Adequate Allocation … Quality Assessment of Included Randomized, Controlled Trials
image1.jpeg
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
March 01, 2009 - A1-2
12 exp Randomized Controlled Trials/
13 randomized controlled trial.pt.
14 rct$.mp.
15 11 … Benefits among
population subgroups†
• Randomized, double-blind, placebo controlled trials
of tamoxifen … Harms among
population subgroups†
• Randomized, double-blind, placebo controlled trials
of tamoxifen … A controlled trial of raloxifene (LY139481)
HCl: impact on bone turnover and serum lipid profile in … Randomized, double-blind,
placebo-controlled study of the effects of raloxifene and conjugated equine
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/traumatic-brain-injury-rehabilitation-surveillance-160902.pdf
May 29, 2025 - .$(167821)$
10$$$$$randomized$controlled$trial/$(416302)$
11$$$$$clinical$trial/$(500056)$
12$$$$$ … $controlled$trial. … $controlled$trial. … $A$randomized$controlled$trial$of$emotion$
recognition$training$after$traumatic$brain$injury. … $controlled$trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/outcomes-dental-services-rapid-research.pdf
May 01, 2025 - ROBINS-I gave non-randomized controlled interventional studies a score of low,
moderate, serious, or … controlled trial; RoB: risk of bias; SUD: substance use disorder. … controlled trial; SUD: substance
use disorder.
3.3.1 Results, Key Question 2, Key Points
12 … A
Randomised Controlled Trial of a Smoking
Cessation Intervention Delivered by Dental
Hygienists: … controlled trial
RoB Risk of bias
RR Relative risk
SME Subject matter expert
SR Systematic review
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
December 01, 2024 - duration, treatment arms, dosage, number of participants randomized and
analyzed, study sites, and … Placebo-Controlled Versus Active-Controlled Trials: FDA reviews primarily focus
on placebo-controlled … Control type Placebo-
controlled trials
Active-controlled trials FDA reviews primarily focused on placebo … -
controlled but may include both. … clinical trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/c-difficile-future_research.pdf
October 26, 2012 - controlled trial
A-1
Appendix A. … CDI = Clostridium difficile infection; RCT = randomized controlled trial
B-1
Appendix B. … (randomized controlled trial*) OR (comparative study) OR (controlled clinical trial) OR
RCT[title] … OR randomized[tiab] OR placebo[tiab] OR trial[tiab]
4 … (randomized controlled trial*) OR (comparative study) OR (controlled clinical trial) OR
RCT[title]
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1406.pdf
June 01, 2014 - controlled trial; however, no such trials are planned. … controlled trial, patients (n=56) with unicompartmental osteoarthritis of the
knee and genu varum … controlled trial, patients (n=49) aged 40–50 years with early OA
and cartilage lesions less than 4 … controlled clinical
trial with 2 years' follow-up. … controlled trial.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
October 01, 2010 - Randomized controlled trials (RCT) of A vs. … In principle, studies from different randomized trial designs,
e.g. parallel, cross-over, factorial … The results of direct and indirect treatment
comparisons in meta-analysis of randomized
controlled … Randomized, controlled trials, observational
studies, and the hierarchy of research
designs. … A comparison of
observational studies and randomized,
controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
October 01, 2010 - Randomized controlled trials (RCT) of A vs. … In principle, studies from different randomized trial designs,
e.g. parallel, cross-over, factorial … The results of direct and indirect treatment
comparisons in meta-analysis of randomized
controlled … Randomized, controlled trials, observational
studies, and the hierarchy of research
designs. … A comparison of
observational studies and randomized,
controlled trials.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-d.xlsx
January 01, 2023 - No masking, but no indication of deviations due to trial context. … sample, unclear analysis plan
SAMIT OS Low Low Low Some concerns High High This is a factorial 2x2 randomized … controlled trial. … SAMIT Grade 3 to 5 AEs Low Low Low Some concerns High High This is a factorial 2x2 randomized controlled … trial.