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effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-g-surv-report-2-nonopioid-pharmacol-chronic-pain.xlsx
October 08, 2025 - Quality assessments of included randomized controlled trials
Author, Year Randomization Adequate Allocation … Quality Assessment of Included Randomized, Controlled Trials
image1.jpeg
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-draft-report-appendix-e.xlsx
January 01, 2023 - Risk of bias assessments for randomized controlled trials (RCTs) evaluating fusion procedures for degenerative … Unclear Unclear Yes High
9085/4824/4988/5532 Friedly, 2014, 2019; Kolodge 2023; Makris 2017 (LESS/LESSER trial … Yes Yes (through 12 years) Yes Yes Yes Moderate
3632 Kang, 2012 3 Yes Unclear Unclear, data for all randomized … Quality Rating
Low/Moderate/High
9290
2229 Abdu, 2009
Abdu, 2018 2 Original sample randomized No Yes … controlled trial
RFA radiofrequency ablation
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research.pdf
June 01, 2017 - Matching Studies
We matched randomized controlled trials (RCTs) identified in CT.gov with those identified … randomized trial. … , controlled trial. … PCOSMIC: a multi-centre randomized trial
in women with PolyCystic Ovary Syndrome
evaluating Metformin … controlled trial.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb_surveillance.pdf
July 06, 2015 - controlled or observational trial, not a comparison of
ACE inhibitor, ARB or their combination versus … controlled trial (RCT) or 1000 (observational study) patients,
or was not at least 6 months duration … controlled or observational trial,
not a comparison of ACE inhibitor, ARB or their combination versus … Disease) trial was the only placebo-
controlled trial available to evaluate major efficacy
outcomes … was the
only placebo-controlled trial
available to evaluate major efficacy
Possibly out of date
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_surveillance.pdf
August 01, 2012 - In a randomized,
controlled trial presented at a conference but not
yet published, the risk difference … Quality of life was
reported in one randomized, controlled trial and
two observational studies and … The single randomized,
controlled trial had too small of a sample size and
too short of a follow up … In a randomized, controlled
trial presented at a conference but not yet published,
the risk difference … The single randomized, controlled
trial had too small of a sample size and too short of a
followup
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-app-f.xlsx
January 01, 2019 - Quality assessments for randomized controlled trials evaluating external beam radiation therapy for the … Unclear Unclear Yes Fair
Badzio, 2003 Yes Yes Yes No No No Yes Yes Yes Unclear Yes Fair
Bone Pain Trial … 1994 Unclear Unclear No Yes (CROs)
No (PROs) Yes No No Unclear Unclear Unclear Yes Poor
Sprave, 2018 Randomized … NRSI nonrandomized study of interventions
PRO patient-reported outcome
QA quality assessment
RCT randomized … controlled trial
RT radiation therapy
SBRT stereotactic body radiation therapy
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-presentation-format_research.pdf
January 01, 2019 - In 20 out of these 23 papers the recommendation was that more randomized controlled
trials are necessary … Overall, the frequency of recommending further randomized controlled trials was
significantly different … For example, if it is deemed that a randomized trial is important, one could do a
power analysis under … controlled trial
VOI Value of information
A-1
7BAppendix A. … Year Journal
20133502 Economic evaluation of the DiAMOND randomized trial: cost
and outcomes of 2
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - controlled trial
B. … (COMET): randomised controlled trial. … controlled trial. … Surgical Maze procedure as a treatment for atrial
fibrillation: a meta-analysis of randomized controlled … controlled trial(s)
WHO World Health Organization
VII.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - We will search
MEDLINE® for randomized controlled trials, non-randomized comparative studies, … We will search EMBASE® for randomized controlled trials, non-randomized
comparative studies, and case … Intention-to-treat analysis is done for randomized, controlled trials. … analysis
↑ Randomized trial, post-hoc multivariate subgroup analysis
Continuum Randomized trial … The most informative
scenario would be a trial in which randomized assignment to treatment groups
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - Additionally, randomized controlled trials will be assessed for randomization
technique and allocation … A multicenter, randomized, double-blind,
placebo-controlled trial to evaluate the metabolic and respiratory … controlled trial. … controlled trial.pt.
15. controlled clinical trial.pt.
16. randomized.ab.
17. placebo.ab.
18. drug … controlled trial.pt.
15. controlled clinical trial.pt.
16. randomized.ab.
17. placebo.ab.
18. drug
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-nonpharmacologic-treatment_research-protocol.pdf
October 04, 2016 - Study Design Criteria
Systematic reviews, meta-analyses, and randomized controlled trials (RCTs) will … study filter
(Key Question 1)
9 AND ('randomized controlled trial'/exp OR 'randomized controlled … study'/exp OR 'controlled study' OR 'clinical trial'/exp OR 'clinical trial' OR
'comparative study … study filter plus case
reports (Key Question
2)
13 AND ('randomized controlled trial'/exp OR 'randomized … study'/exp OR 'controlled study' OR 'clinical trial'/exp OR 'clinical trial' OR
'comparative study
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/fibromyalgia_research-protocol.pdf
April 03, 2014 - Study designs • Randomized clinical trials (RCTs), nonrandomized controlled trials, and
prospective … KQ = key question; RCT = randomized controlled trial
B. … controlled trials. … Adverse events attributable to nocebo in
randomized controlled drug trials in fibromyalgia syndrome … controlled
trials
as
topic/
(102691)
34
randomized
controlled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/procalcitonin_executive.pdf
October 01, 2012 - controlled trial. … ): a multicentre randomised controlled trial. … controlled trial. … Antibiotic treatment
of exacerbations of COPD: a randomized, controlled trial
comparing procalcitonin-guidance … controlled trial.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/back-pain-treatment_clinician.pdf
November 01, 2016 - ; ↔ = no difference between the interventions; NSAID = nonsteroidal anti-inflammatory drug;
RCT = randomized … controlled trial; SOE = strength of evidence; SR = systematic review
+ = small effect favoring the … controlled trial; SOE = strength of evidence; SR = systematic review
Archived: This report is greater … controlled trial; SOE = strength of evidence; SR = systematic review
** A retraining program to improve … ,
controlled trial suggests that acetaminophen is ineffective
in treating acute low back pain (low
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-g-surv-report-3-nonopioid-pharmacol-chronic-pain.xlsx
October 08, 2025 - Quality assessments of included randomized controlled trials
Author, Year Randomization Adequate Allocation … Quality Assessment of Included Randomized, Controlled Trials
image1.jpeg
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/rotator-cuff-tear-surveillance-140925.pdf
February 01, 2014 - More, specifically, one systematic review and
one randomized controlled trial (RCT) suggest that surgical … Platelet-rich plasma augmentation for
arthroscopic rotator cuff repair: a
randomized controlled trial … controlled trial/ or exp "randomized controlled trial (topic)"/ (681874)
77 exp randomization/ (155079 … =versus RCT=randomized controlled trial; CER=comparative effectiveness review; SLAP=
superior labral … CER=comparative effectiveness review; RCT=randomized controlled trial; IQR=interquartile range
79
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adult-treatment_executive.pdf
April 01, 2013 - We included randomized
controlled trials (RCTs) of at least 4 weeks in duration
for KQs 1 through 5 … controlled trial. … A randomized, controlled
proof-of-concept trial of an Internet-based, therapist-assisted self-
management … A multisite randomized
controlled effectiveness trial of cognitive processing therapy for
military-related … A randomized,
double-blind, placebo-controlled trial on the efficacy and
tolerability of sertraline
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/carbohydrate-intake-executive-summary.pdf
May 01, 2025 - • During infancy:
o One trial that was not large or rigorous enough to support a conclusion was … We included randomized controlled trials,
nonrandomized intervention studies, and observational studies … Of the eight studies, two were randomized controlled trials, one rated low and the
other rated high … Trial. … controlled trial.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/pharma-nonpharma-ptsd-2023-update-executive-summ.pdf
January 01, 2023 - Repository
Executive Summary
Main Points
• This update adds 60 newly published randomized … controlled trials (RCTs) on
posttraumatic stress disorder (PTSD) and comorbid PTSD/substance use disorder … • This update also includes risk of bias (RoB) using the updated Cochrane RoB 2
tool for randomized … Controlled Trial Data. … Development of the PTSD-Repository: a
publicly available repository of randomized
controlled trials
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_surveillance.pdf
October 01, 2012 - controlled trial. … Sulodexide for kidney protection in type 2
diabetes patients with microalbuminuria: a
randomized controlled … (randomized controlled trial or controlled clinical trial).pt. or random*.ti,ab. or
placebo.ab. or … (randomized controlled trial or controlled clinical trial).pt. or random*.ti,ab. or
placebo.ab. or exp … (randomized controlled trial or controlled clinical trial).pt. or random*.ti,ab. or
placebo.ab. or